3O3IX

Crystal structure of human hiwi1 paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2'-oh at its 3'-end
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
118
structure length
108
Chain Sequence
SETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKGPAMLIPELCYLTGLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
pubmed doi rcsb
molecule tags Rna binding protein
source organism Homo sapiens
molecule keywords Piwi-like protein 1
total genus 21
structure length 108
sequence length 118
ec nomenclature
pdb deposition date 2010-07-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 3o3iX00
4OLBA 2XFMA 4NGFA 1R4KA 4W5QA 3O7VX 4W5NA 4NGDA 4Z4IA 2L5CA 5T7BA 4Z4HA 3O6EX 4KREA 1VYNA 4OLAA 2QVWA 1T2RA 4W5OA 5KI6A 4Z4CA 4NGGA 1SI3A 4W5RA 5JS2A 4NGCA 3O3IX 3QIRA 4NH3A 4KRFA 4W5TA 1T2SA 4Z4EA 4NHAA 5JS1A 4NGBA 2FFLA 3MJ0A 3O7XA 1R6ZA 2L5DA 4Z4FA 4F3TA 4NH6A 4Z4GA 1SI2A 4NH5A
chains in the Genus database with same CATH superfamily
3U1UA 4OLBA 2XFMA 4NGFA 3DA5A 3HJFA 1R4KA 4W5QA 3O7VX 4W5NA 4NGDA 4Z4IA 2L5CA 1U04A 3HM9A 3HK2A 2BZEA 5T7BA 4Z4HA 3O6EX 3HO1A 4KREA 1VYNA 4OLAA 2QVWA 1T2RA 4W5OA 5KI6A 4Z4CA 4NGGA 1Z25A 1SI3A 4W5RA 4L1PA 5JS2A 3HVRA 3O3IX 3QIRA 3F73A 4NGCA 4NH3A 4KRFA 4W5TA 1T2SA 4Z4EA 3DLHA 4NHAA 4NGBA 5JS1A 2FFLA 3MJ0A 3O7XA 1R6ZA 2DB9A 1Z26A 2L5DA 4Z4FA 4F3TA 4L1UA 4NH6A 4Z4GA 1SI2A 3DLBA 4NH5A
chains in the Genus database with same CATH topology
3U1UA 4OLBA 2XFMA 4NGFA 3DA5A 3HJFA 1R4KA 4W5QA 3O7VX 4W5NA 4NGDA 4Z4IA 2L5CA 1U04A 3HM9A 3HK2A 2BZEA 5T7BA 4Z4HA 3O6EX 3HO1A 4KREA 1VYNA 4OLAA 2QVWA 1T2RA 4W5OA 5KI6A 4Z4CA 4NGGA 1Z25A 1SI3A 4W5RA 4L1PA 5JS2A 3HVRA 3O3IX 3QIRA 3F73A 4NGCA 4NH3A 4KRFA 4W5TA 1T2SA 4Z4EA 3DLHA 4NHAA 4NGBA 5JS1A 2FFLA 3MJ0A 3O7XA 1R6ZA 2DB9A 1Z26A 2L5DA 4Z4FA 4F3TA 4L1UA 4NH6A 4Z4GA 1SI2A 3DLBA 4NH5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OLB A;  2XFM A;  4NGF A;  1R4K A;  4W5Q A;  3O7V X;  4W5N A;  4NGD A;  4Z4I A;  2L5C A;  5T7B A;  4Z4H A;  3O6E X;  4KRE A;  1VYN A;  4OLA A;  2QVW A;  1T2R A;  4W5O A;  5KI6 A;  4Z4C A;  4NGG A;  1SI3 A;  4W5R A;  5JS2 A;  4NGC A;  3O3I X;  3QIR A;  4NH3 A;  4KRF A;  4W5T A;  1T2S A;  4Z4E A;  4NHA A;  5JS1 A;  4NGB A;  2FFL A;  3MJ0 A;  3O7X A;  1R6Z A;  2L5D A;  4Z4F A;  4F3T A;  4NH6 A;  4Z4G A;  1SI2 A;  4NH5 A; 
#chains in the Genus database with same CATH topology
 3U1U A;  4OLB A;  2XFM A;  4NGF A;  3DA5 A;  3HJF A;  1R4K A;  4W5Q A;  3O7V X;  4W5N A;  4NGD A;  4Z4I A;  2L5C A;  1U04 A;  3HM9 A;  3HK2 A;  2BZE A;  5T7B A;  4Z4H A;  3O6E X;  3HO1 A;  4KRE A;  1VYN A;  4OLA A;  2QVW A;  1T2R A;  4W5O A;  5KI6 A;  4Z4C A;  4NGG A;  1Z25 A;  1SI3 A;  4W5R A;  4L1P A;  5JS2 A;  3HVR A;  3O3I X;  3QIR A;  3F73 A;  4NGC A;  4NH3 A;  4KRF A;  4W5T A;  1T2S A;  4Z4E A;  3DLH A;  4NHA A;  4NGB A;  5JS1 A;  2FFL A;  3MJ0 A;  3O7X A;  1R6Z A;  2DB9 A;  1Z26 A;  2L5D A;  4Z4F A;  4F3T A;  4L1U A;  4NH6 A;  4Z4G A;  1SI2 A;  3DLB A;  4NH5 A; 
#chains in the Genus database with same CATH homology
 3U1U A;  4OLB A;  2XFM A;  4NGF A;  3DA5 A;  3HJF A;  1R4K A;  4W5Q A;  3O7V X;  4W5N A;  4NGD A;  4Z4I A;  2L5C A;  1U04 A;  3HM9 A;  3HK2 A;  2BZE A;  5T7B A;  4Z4H A;  3O6E X;  3HO1 A;  4KRE A;  1VYN A;  4OLA A;  2QVW A;  1T2R A;  4W5O A;  5KI6 A;  4Z4C A;  4NGG A;  1Z25 A;  1SI3 A;  4W5R A;  4L1P A;  5JS2 A;  3HVR A;  3O3I X;  3QIR A;  3F73 A;  4NGC A;  4NH3 A;  4KRF A;  4W5T A;  1T2S A;  4Z4E A;  3DLH A;  4NHA A;  4NGB A;  5JS1 A;  2FFL A;  3MJ0 A;  3O7X A;  1R6Z A;  2DB9 A;  1Z26 A;  2L5D A;  4Z4F A;  4F3T A;  4L1U A;  4NH6 A;  4Z4G A;  1SI2 A;  3DLB A;  4NH5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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