3O6EX

Crystal structure of human hiwi1 paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2'-och3 at its 3'-end
Total Genus 20
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
117
structure length
107
Chain Sequence
ETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKGPAMLIPELCYLTGLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords Piwi-like protein 1
total genus 20
structure length 107
sequence length 117
ec nomenclature
pdb deposition date 2010-07-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 3o6eX00
5JS2A 3O7XA 1SI2A 4NGFA 1T2SA 4W5OA 3O7VX 1SI3A 4NH6A 4NGDA 4W5TA 1T2RA 4KRFA 4W5RA 4Z4IA 1R6ZA 4OLBA 1R4KA 4OLAA 4F3TA 4W5NA 2XFMA 1VYNA 4Z4CA 2L5DA 4NGBA 3QIRA 5KI6A 4Z4GA 4NH3A 4NGGA 4NH5A 4NGCA 4Z4EA 3O6EX 5JS1A 5T7BA 4KREA 4W5QA 3O3IX 4Z4FA 2L5CA 2QVWA 2FFLA 4NHAA 4Z4HA 3MJ0A
chains in the Genus database with same CATH superfamily
3HM9A 5JS2A 3HJFA 3O7XA 1SI2A 3HK2A 4L1PA 4NGFA 1U04A 4W5OA 1T2SA 1Z26A 3F73A 1SI3A 4W5TA 1T2RA 3O7VX 4NH6A 4NGDA 3DA5A 4KRFA 4W5RA 4L1UA 4Z4IA 2DB9A 1R6ZA 4OLBA 1R4KA 4OLAA 3U1UA 3HO1A 4F3TA 4W5NA 2XFMA 1VYNA 4Z4CA 2BZEA 2L5DA 3QIRA 5KI6A 4NGBA 4Z4GA 4NH3A 4NGGA 4NH5A 4NGCA 4Z4EA 3O6EX 3HVRA 5JS1A 5T7BA 4KREA 4W5QA 3O3IX 3DLBA 4Z4FA 2L5CA 2QVWA 1Z25A 2FFLA 4NHAA 3DLHA 4Z4HA 3MJ0A
chains in the Genus database with same CATH topology
3HM9A 5JS2A 3HJFA 3O7XA 1SI2A 3HK2A 4L1PA 4NGFA 1U04A 4W5OA 1T2SA 1Z26A 3F73A 1SI3A 4W5TA 1T2RA 3O7VX 4NH6A 4NGDA 3DA5A 4KRFA 4W5RA 4L1UA 4Z4IA 2DB9A 1R6ZA 4OLBA 1R4KA 4OLAA 3U1UA 3HO1A 4F3TA 4W5NA 2XFMA 1VYNA 4Z4CA 2BZEA 2L5DA 3QIRA 5KI6A 4NGBA 4Z4GA 4NH3A 4NGGA 4NH5A 4NGCA 4Z4EA 3O6EX 3HVRA 5JS1A 5T7BA 4KREA 4W5QA 3O3IX 3DLBA 4Z4FA 2L5CA 2QVWA 1Z25A 2FFLA 4NHAA 3DLHA 4Z4HA 3MJ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JS2 A;  3O7X A;  1SI2 A;  4NGF A;  1T2S A;  4W5O A;  3O7V X;  1SI3 A;  4NH6 A;  4NGD A;  4W5T A;  1T2R A;  4KRF A;  4W5R A;  4Z4I A;  1R6Z A;  4OLB A;  1R4K A;  4OLA A;  4F3T A;  4W5N A;  2XFM A;  1VYN A;  4Z4C A;  2L5D A;  4NGB A;  3QIR A;  5KI6 A;  4Z4G A;  4NH3 A;  4NGG A;  4NH5 A;  4NGC A;  4Z4E A;  3O6E X;  5JS1 A;  5T7B A;  4KRE A;  4W5Q A;  3O3I X;  4Z4F A;  2L5C A;  2QVW A;  2FFL A;  4NHA A;  4Z4H A;  3MJ0 A; 
#chains in the Genus database with same CATH topology
 3HM9 A;  5JS2 A;  3HJF A;  3O7X A;  1SI2 A;  3HK2 A;  4L1P A;  4NGF A;  1U04 A;  4W5O A;  1T2S A;  1Z26 A;  3F73 A;  1SI3 A;  4W5T A;  1T2R A;  3O7V X;  4NH6 A;  4NGD A;  3DA5 A;  4KRF A;  4W5R A;  4L1U A;  4Z4I A;  2DB9 A;  1R6Z A;  4OLB A;  1R4K A;  4OLA A;  3U1U A;  3HO1 A;  4F3T A;  4W5N A;  2XFM A;  1VYN A;  4Z4C A;  2BZE A;  2L5D A;  3QIR A;  5KI6 A;  4NGB A;  4Z4G A;  4NH3 A;  4NGG A;  4NH5 A;  4NGC A;  4Z4E A;  3O6E X;  3HVR A;  5JS1 A;  5T7B A;  4KRE A;  4W5Q A;  3O3I X;  3DLB A;  4Z4F A;  2L5C A;  2QVW A;  1Z25 A;  2FFL A;  4NHA A;  3DLH A;  4Z4H A;  3MJ0 A; 
#chains in the Genus database with same CATH homology
 3HM9 A;  5JS2 A;  3HJF A;  3O7X A;  1SI2 A;  3HK2 A;  4L1P A;  4NGF A;  1U04 A;  4W5O A;  1T2S A;  1Z26 A;  3F73 A;  1SI3 A;  4W5T A;  1T2R A;  3O7V X;  4NH6 A;  4NGD A;  3DA5 A;  4KRF A;  4W5R A;  4L1U A;  4Z4I A;  2DB9 A;  1R6Z A;  4OLB A;  1R4K A;  4OLA A;  3U1U A;  3HO1 A;  4F3T A;  4W5N A;  2XFM A;  1VYN A;  4Z4C A;  2BZE A;  2L5D A;  3QIR A;  5KI6 A;  4NGB A;  4Z4G A;  4NH3 A;  4NGG A;  4NH5 A;  4NGC A;  4Z4E A;  3O6E X;  3HVR A;  5JS1 A;  5T7B A;  4KRE A;  4W5Q A;  3O3I X;  3DLB A;  4Z4F A;  2L5C A;  2QVW A;  1Z25 A;  2FFL A;  4NHA A;  3DLH A;  4Z4H A;  3MJ0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...