3O7VX

Crystal structure of human hiwi1 (v361m) paz domain (residues 277-399) in complex with 14-mer rna (12-bp + 2-nt overhang) containing 2'-och3 at its 3'-end
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
117
structure length
107
Chain Sequence
ETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDLKQPMLVSQPKGPAMLIPELCYLTGLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Inaugural Article: Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
pubmed doi rcsb
molecule tags Rna binding protein/rna
source organism Homo sapiens
molecule keywords Piwi-like protein 1
total genus 22
structure length 107
sequence length 117
ec nomenclature
pdb deposition date 2010-08-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 3o7vX00
4Z4CA 1T2SA 1R4KA 4W5QA 3O3IX 4Z4IA 4NGCA 3O7XA 5T7BA 4Z4GA 2QVWA 1SI2A 4NH5A 4KREA 4W5TA 2L5DA 4W5NA 3O6EX 4NHAA 4NGFA 4NGDA 3MJ0A 5JS2A 3QIRA 4Z4HA 1SI3A 2XFMA 1VYNA 4KRFA 1R6ZA 4OLBA 4Z4FA 4NGBA 4OLAA 4W5RA 3O7VX 2L5CA 2FFLA 4NH3A 4Z4EA 5KI6A 4NGGA 1T2RA 5JS1A 4W5OA 4NH6A 4F3TA
chains in the Genus database with same CATH superfamily
4Z4CA 1T2SA 1R4KA 4W5QA 3U1UA 3O3IX 3DLHA 4Z4IA 3F73A 4NGCA 3O7XA 5T7BA 4Z4GA 2DB9A 2QVWA 1SI2A 4NH5A 4W5TA 2L5DA 4KREA 4W5NA 3O6EX 4NHAA 4NGFA 3DA5A 3MJ0A 4NGDA 5JS2A 3HM9A 1Z26A 4F3TA 3HO1A 3QIRA 3HK2A 4Z4HA 1SI3A 2XFMA 1Z25A 1VYNA 4KRFA 1R6ZA 4OLBA 4Z4FA 4NGBA 4OLAA 3DLBA 4W5RA 3O7VX 2L5CA 2FFLA 4NH3A 2BZEA 3HVRA 4Z4EA 5KI6A 4NGGA 1T2RA 5JS1A 4W5OA 4L1PA 4L1UA 4NH6A 3HJFA 1U04A
chains in the Genus database with same CATH topology
4Z4CA 1T2SA 1R4KA 4W5QA 3U1UA 3O3IX 3DLHA 4Z4IA 3F73A 4NGCA 3O7XA 5T7BA 4Z4GA 2DB9A 2QVWA 1SI2A 4NH5A 4W5TA 2L5DA 4KREA 4W5NA 3O6EX 4NHAA 4NGFA 3DA5A 3MJ0A 4NGDA 5JS2A 3HM9A 1Z26A 4F3TA 3HO1A 3QIRA 3HK2A 4Z4HA 1SI3A 2XFMA 1Z25A 1VYNA 4KRFA 1R6ZA 4OLBA 4Z4FA 4NGBA 4OLAA 3DLBA 4W5RA 3O7VX 2L5CA 2FFLA 4NH3A 2BZEA 3HVRA 4Z4EA 5KI6A 4NGGA 1T2RA 5JS1A 4W5OA 4L1PA 4L1UA 4NH6A 3HJFA 1U04A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z4C A;  1T2S A;  1R4K A;  4W5Q A;  3O3I X;  4Z4I A;  4NGC A;  3O7X A;  5T7B A;  4Z4G A;  2QVW A;  1SI2 A;  4NH5 A;  4KRE A;  4W5T A;  2L5D A;  4W5N A;  3O6E X;  4NHA A;  4NGF A;  4NGD A;  3MJ0 A;  5JS2 A;  3QIR A;  4Z4H A;  1SI3 A;  2XFM A;  1VYN A;  4KRF A;  1R6Z A;  4OLB A;  4Z4F A;  4NGB A;  4OLA A;  4W5R A;  3O7V X;  2L5C A;  2FFL A;  4NH3 A;  4Z4E A;  5KI6 A;  4NGG A;  1T2R A;  5JS1 A;  4W5O A;  4NH6 A;  4F3T A; 
#chains in the Genus database with same CATH topology
 4Z4C A;  1T2S A;  1R4K A;  4W5Q A;  3U1U A;  3O3I X;  3DLH A;  4Z4I A;  3F73 A;  4NGC A;  3O7X A;  5T7B A;  4Z4G A;  2DB9 A;  2QVW A;  1SI2 A;  4NH5 A;  4W5T A;  2L5D A;  4KRE A;  4W5N A;  3O6E X;  4NHA A;  4NGF A;  3DA5 A;  3MJ0 A;  4NGD A;  5JS2 A;  3HM9 A;  1Z26 A;  4F3T A;  3HO1 A;  3QIR A;  3HK2 A;  4Z4H A;  1SI3 A;  2XFM A;  1Z25 A;  1VYN A;  4KRF A;  1R6Z A;  4OLB A;  4Z4F A;  4NGB A;  4OLA A;  3DLB A;  4W5R A;  3O7V X;  2L5C A;  2FFL A;  4NH3 A;  2BZE A;  3HVR A;  4Z4E A;  5KI6 A;  4NGG A;  1T2R A;  5JS1 A;  4W5O A;  4L1P A;  4L1U A;  4NH6 A;  3HJF A;  1U04 A; 
#chains in the Genus database with same CATH homology
 4Z4C A;  1T2S A;  1R4K A;  4W5Q A;  3U1U A;  3O3I X;  3DLH A;  4Z4I A;  3F73 A;  4NGC A;  3O7X A;  5T7B A;  4Z4G A;  2DB9 A;  2QVW A;  1SI2 A;  4NH5 A;  4W5T A;  2L5D A;  4KRE A;  4W5N A;  3O6E X;  4NHA A;  4NGF A;  3DA5 A;  3MJ0 A;  4NGD A;  5JS2 A;  3HM9 A;  1Z26 A;  4F3T A;  3HO1 A;  3QIR A;  3HK2 A;  4Z4H A;  1SI3 A;  2XFM A;  1Z25 A;  1VYN A;  4KRF A;  1R6Z A;  4OLB A;  4Z4F A;  4NGB A;  4OLA A;  3DLB A;  4W5R A;  3O7V X;  2L5C A;  2FFL A;  4NH3 A;  2BZE A;  3HVR A;  4Z4E A;  5KI6 A;  4NGG A;  1T2R A;  5JS1 A;  4W5O A;  4L1P A;  4L1U A;  4NH6 A;  3HJF A;  1U04 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...