3TBLA

Structure of mono-ubiquitinated pcna: implications for dna polymerase switching and okazaki fragment maturation
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
256
structure length
250
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation.
pubmed doi rcsb
molecule tags Replication
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 59
structure length 250
sequence length 256
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2011-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 3tblA00
2AWAA 2IO4B 3G65B 2HIKC 3LX1A 3U60F 2IZOB 2IX2C 2NTIC 2HIIB 3GGRA 5AUJA 3P83A 3P87A 5JNED 4TR6A 2ZVMA 5DA7A 2ZVKA 3AIZA 1T6LA 3I2MX 2HIKB 1PLQA 2OD8A 2IX2B 2NTIB 3FDSD 4ZTDA 4HK1A 3AIXB 1IZ5A 3F1WA 1RWZA 5E0VA 1U7BA 2ZVLA 1ISQA 2Z0LA 5E0UA 3A1JA 3P91A 3V62B 3VKXA 3U61F 3GGRC 1PLRA 4L6PA 1VYJA 3GPNA 1RXZA 3U5ZF 1AXCA 4YHRA 2ZVVA 5HACA 3GGRB 5DAIA 1UL1A 2IO4A 2ZVWA 5E0TA 3V61B 3G65A 3GPMA 1B77A 1CZDA 2HIIA 2IJXA 3K4XA 3A1JC 3TBLA 1VYMA 1RXMA 5A6DA 3HSLX 1IZ4A 3IFVA 3HI8A 1UD9A 3AIZC 2HIKA 3FDSC 1YYPA 5IWDA 2IX2A 3WGWA 2NTIA 3LX2A 5B7OA 5CFKA 3V60B 3A1JB 3AIXA 1W60A 3A2FB 1B8HA 4RJFA 4CS5A 1U76A 3G65C 5IXAA 5IY4A 5H0TA 4D2GA 2IZOC 2AVTA 1SXJF 1GE8A 2HIIC 1DMLA 4L60A
chains in the Genus database with same CATH superfamily
2AWAA 2IO4B 3G65B 2HIKC 3LX1A 3U60F 2IZOB 2IX2C 2NTIC 2HIIB 3GGRA 5AUJA 3P83A 3P87A 5JNED 4TR6A 2ZVMA 5DA7A 2ZVKA 3AIZA 1T6LA 3I2MX 2HIKB 1PLQA 2OD8A 2IX2B 2NTIB 3FDSD 4ZTDA 4HK1A 3AIXB 1IZ5A 3F1WA 1RWZA 5E0VA 1U7BA 2ZVLA 1ISQA 2Z0LA 5E0UA 3A1JA 3P91A 3V62B 3VKXA 3U61F 3GGRC 1PLRA 4L6PA 1VYJA 3GPNA 1RXZA 3U5ZF 1AXCA 4YHRA 2ZVVA 5HACA 3GGRB 5DAIA 1UL1A 2IO4A 2ZVWA 5E0TA 3V61B 3G65A 3GPMA 1B77A 1CZDA 2HIIA 2IJXA 3K4XA 3A1JC 3TBLA 1VYMA 1RXMA 5A6DA 3HSLX 1IZ4A 3IFVA 3HI8A 1UD9A 3AIZC 2HIKA 3FDSC 1YYPA 5IWDA 2IX2A 3WGWA 2NTIA 3LX2A 5B7OA 5CFKA 3V60B 3A1JB 3AIXA 1W60A 3A2FB 1B8HA 4RJFA 4CS5A 1U76A 3G65C 5IXAA 5IY4A 5H0TA 4D2GA 2IZOC 2AVTA 1SXJF 1GE8A 2HIIC 1DMLA 4L60A
chains in the Genus database with same CATH topology
2AWAA 2IO4B 3G65B 2HIKC 3LX1A 3U60F 2IZOB 2IX2C 2NTIC 2HIIB 3GGRA 5AUJA 3P83A 3P87A 5JNED 4TR6A 2ZVMA 5DA7A 2ZVKA 3AIZA 1T6LA 3I2MX 2HIKB 1PLQA 2OD8A 2IX2B 2NTIB 3FDSD 4ZTDA 4HK1A 3AIXB 1IZ5A 3F1WA 1RWZA 5E0VA 1U7BA 2ZVLA 1ISQA 2Z0LA 5E0UA 3A1JA 3P91A 3V62B 3VKXA 3U61F 3GGRC 1PLRA 4L6PA 1VYJA 3GPNA 1RXZA 3U5ZF 1AXCA 4YHRA 2ZVVA 5HACA 3GGRB 5DAIA 1UL1A 2IO4A 2ZVWA 5E0TA 3V61B 3G65A 3GPMA 1B77A 1CZDA 2HIIA 2IJXA 3K4XA 3A1JC 3TBLA 1VYMA 1RXMA 5A6DA 3HSLX 1IZ4A 3IFVA 3HI8A 1UD9A 3AIZC 2HIKA 3FDSC 1YYPA 5IWDA 2IX2A 3WGWA 2NTIA 3LX2A 5B7OA 5CFKA 3V60B 3A1JB 3AIXA 1W60A 3A2FB 1B8HA 4RJFA 4CS5A 1U76A 3G65C 5IXAA 5IY4A 5H0TA 4D2GA 2IZOC 2AVTA 1SXJF 1GE8A 2HIIC 1DMLA 4L60A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AWA A;  2IO4 B;  3G65 B;  2HIK C;  3LX1 A;  3U60 F;  2IZO B;  2IX2 C;  2NTI C;  2HII B;  3GGR A;  5AUJ A;  3P83 A;  3P87 A;  5JNE D;  4TR6 A;  2ZVM A;  5DA7 A;  2ZVK A;  3AIZ A;  1T6L A;  3I2M X;  2HIK B;  1PLQ A;  2OD8 A;  2IX2 B;  2NTI B;  3FDS D;  4ZTD A;  4HK1 A;  3AIX B;  1IZ5 A;  3F1W A;  1RWZ A;  5E0V A;  1U7B A;  2ZVL A;  1ISQ A;  2Z0L A;  5E0U A;  3A1J A;  3P91 A;  3V62 B;  3VKX A;  3U61 F;  3GGR C;  1PLR A;  4L6P A;  1VYJ A;  3GPN A;  1RXZ A;  3U5Z F;  1AXC A;  4YHR A;  2ZVV A;  5HAC A;  3GGR B;  5DAI A;  1UL1 A;  2IO4 A;  2ZVW A;  5E0T A;  3V61 B;  3G65 A;  3GPM A;  1B77 A;  1CZD A;  2HII A;  2IJX A;  3K4X A;  3A1J C;  3TBL A;  1VYM A;  1RXM A;  5A6D A;  3HSL X;  1IZ4 A;  3IFV A;  3HI8 A;  1UD9 A;  3AIZ C;  2HIK A;  3FDS C;  1YYP A;  5IWD A;  2IX2 A;  3WGW A;  2NTI A;  3LX2 A;  5B7O A;  5CFK A;  3V60 B;  3A1J B;  3AIX A;  1W60 A;  3A2F B;  1B8H A;  4RJF A;  4CS5 A;  1U76 A;  3G65 C;  5IXA A;  5IY4 A;  5H0T A;  4D2G A;  2IZO C;  2AVT A;  1SXJ F;  1GE8 A;  2HII C;  1DML A;  4L60 A; 
#chains in the Genus database with same CATH topology
 2AWA A;  2IO4 B;  3G65 B;  2HIK C;  3LX1 A;  3U60 F;  2IZO B;  2IX2 C;  2NTI C;  2HII B;  3GGR A;  5AUJ A;  3P83 A;  3P87 A;  5JNE D;  4TR6 A;  2ZVM A;  5DA7 A;  2ZVK A;  3AIZ A;  1T6L A;  3I2M X;  2HIK B;  1PLQ A;  2OD8 A;  2IX2 B;  2NTI B;  3FDS D;  4ZTD A;  4HK1 A;  3AIX B;  1IZ5 A;  3F1W A;  1RWZ A;  5E0V A;  1U7B A;  2ZVL A;  1ISQ A;  2Z0L A;  5E0U A;  3A1J A;  3P91 A;  3V62 B;  3VKX A;  3U61 F;  3GGR C;  1PLR A;  4L6P A;  1VYJ A;  3GPN A;  1RXZ A;  3U5Z F;  1AXC A;  4YHR A;  2ZVV A;  5HAC A;  3GGR B;  5DAI A;  1UL1 A;  2IO4 A;  2ZVW A;  5E0T A;  3V61 B;  3G65 A;  3GPM A;  1B77 A;  1CZD A;  2HII A;  2IJX A;  3K4X A;  3A1J C;  3TBL A;  1VYM A;  1RXM A;  5A6D A;  3HSL X;  1IZ4 A;  3IFV A;  3HI8 A;  1UD9 A;  3AIZ C;  2HIK A;  3FDS C;  1YYP A;  5IWD A;  2IX2 A;  3WGW A;  2NTI A;  3LX2 A;  5B7O A;  5CFK A;  3V60 B;  3A1J B;  3AIX A;  1W60 A;  3A2F B;  1B8H A;  4RJF A;  4CS5 A;  1U76 A;  3G65 C;  5IXA A;  5IY4 A;  5H0T A;  4D2G A;  2IZO C;  2AVT A;  1SXJ F;  1GE8 A;  2HII C;  1DML A;  4L60 A; 
#chains in the Genus database with same CATH homology
 2AWA A;  2IO4 B;  3G65 B;  2HIK C;  3LX1 A;  3U60 F;  2IZO B;  2IX2 C;  2NTI C;  2HII B;  3GGR A;  5AUJ A;  3P83 A;  3P87 A;  5JNE D;  4TR6 A;  2ZVM A;  5DA7 A;  2ZVK A;  3AIZ A;  1T6L A;  3I2M X;  2HIK B;  1PLQ A;  2OD8 A;  2IX2 B;  2NTI B;  3FDS D;  4ZTD A;  4HK1 A;  3AIX B;  1IZ5 A;  3F1W A;  1RWZ A;  5E0V A;  1U7B A;  2ZVL A;  1ISQ A;  2Z0L A;  5E0U A;  3A1J A;  3P91 A;  3V62 B;  3VKX A;  3U61 F;  3GGR C;  1PLR A;  4L6P A;  1VYJ A;  3GPN A;  1RXZ A;  3U5Z F;  1AXC A;  4YHR A;  2ZVV A;  5HAC A;  3GGR B;  5DAI A;  1UL1 A;  2IO4 A;  2ZVW A;  5E0T A;  3V61 B;  3G65 A;  3GPM A;  1B77 A;  1CZD A;  2HII A;  2IJX A;  3K4X A;  3A1J C;  3TBL A;  1VYM A;  1RXM A;  5A6D A;  3HSL X;  1IZ4 A;  3IFV A;  3HI8 A;  1UD9 A;  3AIZ C;  2HIK A;  3FDS C;  1YYP A;  5IWD A;  2IX2 A;  3WGW A;  2NTI A;  3LX2 A;  5B7O A;  5CFK A;  3V60 B;  3A1J B;  3AIX A;  1W60 A;  3A2F B;  1B8H A;  4RJF A;  4CS5 A;  1U76 A;  3G65 C;  5IXA A;  5IY4 A;  5H0T A;  4D2G A;  2IZO C;  2AVT A;  1SXJ F;  1GE8 A;  2HII C;  1DML A;  4L60 A; 
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