4L60A

Structure of c81r mutant pcna protein defective in mismatch repair
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
256
structure length
256
Chain Sequence
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRRGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFND
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Saccharomyces cerevisiae
molecule keywords Proliferating cell nuclear antigen
total genus 54
structure length 256
sequence length 256
ec nomenclature
pdb deposition date 2013-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4l60A00
2IO4A 1VYMA 3VKXA 1IZ5A 1ISQA 3GGRC 3A2FB 5H0TA 3F1WA 4L60A 3G65B 1B8HA 5HACA 2IX2B 5B7OA 3K4XA 2ZVVA 1U7BA 3A1JC 1PLQA 2ZVLA 3V61B 2NTIC 3A1JA 3U61F 1RXMA 2ZVWA 3AIZC 5DA7A 2IJXA 3AIZA 1RXZA 2HIKB 3LX2A 3WGWA 3U5ZF 3LX1A 2IZOB 1DMLA 3G65C 3P87A 3G65A 3FDSC 5CFKA 2Z0LA 4TR6A 2HIKA 3IFVA 2AVTA 3P91A 5AUJA 2OD8A 1T6LA 3FDSD 4HK1A 1YYPA 2IZOC 5E0TA 1SXJF 3I2MX 3V60B 1VYJA 2IX2C 5DAIA 2IX2A 4YHRA 1UL1A 5E0UA 5IY4A 4L6PA 1B77A 1IZ4A 1RWZA 3GGRB 2HIKC 3V62B 3AIXB 1PLRA 2NTIB 1AXCA 2ZVKA 3GPNA 1CZDA 3HI8A 2HIIB 4RJFA 1GE8A 5IXAA 2IO4B 3GGRA 3TBLA 5A6DA 1U76A 3P83A 3HSLX 3AIXA 3U60F 1W60A 5IWDA 2AWAA 4CS5A 2NTIA 5E0VA 4ZTDA 4D2GA 3GPMA 1UD9A 2ZVMA 2HIIC 5JNED 2HIIA 3A1JB
chains in the Genus database with same CATH superfamily
2IO4A 1VYMA 3VKXA 1IZ5A 1ISQA 3GGRC 3A2FB 5H0TA 3F1WA 4L60A 3G65B 1B8HA 5HACA 2IX2B 5B7OA 3K4XA 2ZVVA 1U7BA 3A1JC 1PLQA 2ZVLA 3V61B 2NTIC 3A1JA 3U61F 1RXMA 2ZVWA 3AIZC 5DA7A 2IJXA 3AIZA 1RXZA 2HIKB 3LX2A 3WGWA 3U5ZF 3LX1A 2IZOB 1DMLA 3G65C 3P87A 3G65A 3FDSC 5CFKA 2Z0LA 4TR6A 2HIKA 3IFVA 2AVTA 3P91A 5AUJA 2OD8A 1T6LA 3FDSD 4HK1A 1YYPA 2IZOC 5E0TA 1SXJF 3I2MX 3V60B 1VYJA 2IX2C 5DAIA 2IX2A 4YHRA 1UL1A 5E0UA 5IY4A 4L6PA 1B77A 1IZ4A 1RWZA 3GGRB 2HIKC 3V62B 3AIXB 1PLRA 2NTIB 1AXCA 2ZVKA 3GPNA 1CZDA 3HI8A 2HIIB 4RJFA 1GE8A 5IXAA 2IO4B 3GGRA 3TBLA 5A6DA 1U76A 3P83A 3HSLX 3AIXA 3U60F 1W60A 5IWDA 2AWAA 4CS5A 2NTIA 5E0VA 4ZTDA 4D2GA 3GPMA 1UD9A 2ZVMA 2HIIC 5JNED 2HIIA 3A1JB
chains in the Genus database with same CATH topology
2IO4A 1VYMA 3VKXA 1IZ5A 1ISQA 3GGRC 3A2FB 5H0TA 3F1WA 4L60A 3G65B 1B8HA 5HACA 2IX2B 5B7OA 3K4XA 2ZVVA 1U7BA 3A1JC 1PLQA 2ZVLA 3V61B 2NTIC 3A1JA 3U61F 1RXMA 2ZVWA 3AIZC 5DA7A 2IJXA 3AIZA 1RXZA 2HIKB 3LX2A 3WGWA 3U5ZF 3LX1A 2IZOB 1DMLA 3G65C 3P87A 3G65A 3FDSC 5CFKA 2Z0LA 4TR6A 2HIKA 3IFVA 2AVTA 3P91A 5AUJA 2OD8A 1T6LA 3FDSD 4HK1A 1YYPA 2IZOC 5E0TA 1SXJF 3I2MX 3V60B 1VYJA 2IX2C 5DAIA 2IX2A 4YHRA 1UL1A 5E0UA 5IY4A 4L6PA 1B77A 1IZ4A 1RWZA 3GGRB 2HIKC 3V62B 3AIXB 1PLRA 2NTIB 1AXCA 2ZVKA 3GPNA 1CZDA 3HI8A 2HIIB 4RJFA 1GE8A 5IXAA 2IO4B 3GGRA 3TBLA 5A6DA 1U76A 3P83A 3HSLX 3AIXA 3U60F 1W60A 5IWDA 2AWAA 4CS5A 2NTIA 5E0VA 4ZTDA 4D2GA 3GPMA 1UD9A 2ZVMA 2HIIC 5JNED 2HIIA 3A1JB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IO4 A;  1VYM A;  3VKX A;  1IZ5 A;  1ISQ A;  3GGR C;  3A2F B;  5H0T A;  3F1W A;  4L60 A;  3G65 B;  1B8H A;  5HAC A;  2IX2 B;  5B7O A;  3K4X A;  2ZVV A;  1U7B A;  3A1J C;  1PLQ A;  2ZVL A;  3V61 B;  2NTI C;  3A1J A;  3U61 F;  1RXM A;  2ZVW A;  3AIZ C;  5DA7 A;  2IJX A;  3AIZ A;  1RXZ A;  2HIK B;  3LX2 A;  3WGW A;  3U5Z F;  3LX1 A;  2IZO B;  1DML A;  3G65 C;  3P87 A;  3G65 A;  3FDS C;  5CFK A;  2Z0L A;  4TR6 A;  2HIK A;  3IFV A;  2AVT A;  3P91 A;  5AUJ A;  2OD8 A;  1T6L A;  3FDS D;  4HK1 A;  1YYP A;  2IZO C;  5E0T A;  1SXJ F;  3I2M X;  3V60 B;  1VYJ A;  2IX2 C;  5DAI A;  2IX2 A;  4YHR A;  1UL1 A;  5E0U A;  5IY4 A;  4L6P A;  1B77 A;  1IZ4 A;  1RWZ A;  3GGR B;  2HIK C;  3V62 B;  3AIX B;  1PLR A;  2NTI B;  1AXC A;  2ZVK A;  3GPN A;  1CZD A;  3HI8 A;  2HII B;  4RJF A;  1GE8 A;  5IXA A;  2IO4 B;  3GGR A;  3TBL A;  5A6D A;  1U76 A;  3P83 A;  3HSL X;  3AIX A;  3U60 F;  1W60 A;  5IWD A;  2AWA A;  4CS5 A;  2NTI A;  5E0V A;  4ZTD A;  4D2G A;  3GPM A;  1UD9 A;  2ZVM A;  2HII C;  5JNE D;  2HII A;  3A1J B; 
#chains in the Genus database with same CATH topology
 2IO4 A;  1VYM A;  3VKX A;  1IZ5 A;  1ISQ A;  3GGR C;  3A2F B;  5H0T A;  3F1W A;  4L60 A;  3G65 B;  1B8H A;  5HAC A;  2IX2 B;  5B7O A;  3K4X A;  2ZVV A;  1U7B A;  3A1J C;  1PLQ A;  2ZVL A;  3V61 B;  2NTI C;  3A1J A;  3U61 F;  1RXM A;  2ZVW A;  3AIZ C;  5DA7 A;  2IJX A;  3AIZ A;  1RXZ A;  2HIK B;  3LX2 A;  3WGW A;  3U5Z F;  3LX1 A;  2IZO B;  1DML A;  3G65 C;  3P87 A;  3G65 A;  3FDS C;  5CFK A;  2Z0L A;  4TR6 A;  2HIK A;  3IFV A;  2AVT A;  3P91 A;  5AUJ A;  2OD8 A;  1T6L A;  3FDS D;  4HK1 A;  1YYP A;  2IZO C;  5E0T A;  1SXJ F;  3I2M X;  3V60 B;  1VYJ A;  2IX2 C;  5DAI A;  2IX2 A;  4YHR A;  1UL1 A;  5E0U A;  5IY4 A;  4L6P A;  1B77 A;  1IZ4 A;  1RWZ A;  3GGR B;  2HIK C;  3V62 B;  3AIX B;  1PLR A;  2NTI B;  1AXC A;  2ZVK A;  3GPN A;  1CZD A;  3HI8 A;  2HII B;  4RJF A;  1GE8 A;  5IXA A;  2IO4 B;  3GGR A;  3TBL A;  5A6D A;  1U76 A;  3P83 A;  3HSL X;  3AIX A;  3U60 F;  1W60 A;  5IWD A;  2AWA A;  4CS5 A;  2NTI A;  5E0V A;  4ZTD A;  4D2G A;  3GPM A;  1UD9 A;  2ZVM A;  2HII C;  5JNE D;  2HII A;  3A1J B; 
#chains in the Genus database with same CATH homology
 2IO4 A;  1VYM A;  3VKX A;  1IZ5 A;  1ISQ A;  3GGR C;  3A2F B;  5H0T A;  3F1W A;  4L60 A;  3G65 B;  1B8H A;  5HAC A;  2IX2 B;  5B7O A;  3K4X A;  2ZVV A;  1U7B A;  3A1J C;  1PLQ A;  2ZVL A;  3V61 B;  2NTI C;  3A1J A;  3U61 F;  1RXM A;  2ZVW A;  3AIZ C;  5DA7 A;  2IJX A;  3AIZ A;  1RXZ A;  2HIK B;  3LX2 A;  3WGW A;  3U5Z F;  3LX1 A;  2IZO B;  1DML A;  3G65 C;  3P87 A;  3G65 A;  3FDS C;  5CFK A;  2Z0L A;  4TR6 A;  2HIK A;  3IFV A;  2AVT A;  3P91 A;  5AUJ A;  2OD8 A;  1T6L A;  3FDS D;  4HK1 A;  1YYP A;  2IZO C;  5E0T A;  1SXJ F;  3I2M X;  3V60 B;  1VYJ A;  2IX2 C;  5DAI A;  2IX2 A;  4YHR A;  1UL1 A;  5E0U A;  5IY4 A;  4L6P A;  1B77 A;  1IZ4 A;  1RWZ A;  3GGR B;  2HIK C;  3V62 B;  3AIX B;  1PLR A;  2NTI B;  1AXC A;  2ZVK A;  3GPN A;  1CZD A;  3HI8 A;  2HII B;  4RJF A;  1GE8 A;  5IXA A;  2IO4 B;  3GGR A;  3TBL A;  5A6D A;  1U76 A;  3P83 A;  3HSL X;  3AIX A;  3U60 F;  1W60 A;  5IWD A;  2AWA A;  4CS5 A;  2NTI A;  5E0V A;  4ZTD A;  4D2G A;  3GPM A;  1UD9 A;  2ZVM A;  2HII C;  5JNE D;  2HII A;  3A1J B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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