4NGCA

Structure of human dicer platform-paz-connector helix cassette in complex with 12-mer sirna having ua-3' ends (2.1 angstrom resolution)
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
299
structure length
276
Chain Sequence
DQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKPALYCVLPLNVVSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 71
structure length 276
sequence length 299
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4ngcA02
4KRFA 4W5QA 5JS2A 4NHAA 4W5OA 1T2RA 4NGDA 4F3TA 3MJ0A 4Z4FA 4W5TA 1SI3A 4OLBA 3O6EX 2FFLA 5KI6A 4NGGA 5JS1A 4OLAA 1R4KA 2QVWA 1VYNA 4Z4IA 4W5RA 1SI2A 4NGBA 4NH3A 1T2SA 4Z4EA 4NH6A 4NGFA 4Z4HA 4NH5A 4Z4CA 3QIRA 1R6ZA 5T7BA 4NGCA 3O7XA 2L5DA 2XFMA 4Z4GA 4KREA 3O3IX 4W5NA 3O7VX 2L5CA
chains in the Genus database with same CATH superfamily
4KRFA 3DLBA 4W5QA 5JS2A 4NHAA 4W5OA 1U04A 1T2RA 3F73A 3HO1A 4NGDA 4F3TA 3MJ0A 4Z4FA 4W5TA 1SI3A 3HK2A 1Z25A 4OLBA 3O6EX 2FFLA 3DLHA 3HVRA 5KI6A 1Z26A 4NGGA 4OLAA 5JS1A 1R4KA 2QVWA 1VYNA 4Z4IA 4W5RA 1SI2A 4NGBA 4NH3A 1T2SA 4L1UA 3U1UA 4Z4EA 3HJFA 4NH6A 2DB9A 4NGFA 4L1PA 4Z4HA 4NH5A 4Z4CA 2BZEA 3DA5A 1R6ZA 3QIRA 5T7BA 3O7XA 2L5DA 2XFMA 4Z4GA 3O7VX 4NGCA 4KREA 3O3IX 4W5NA 3HM9A 2L5CA
chains in the Genus database with same CATH topology
4KRFA 3DLBA 4W5QA 5JS2A 4NHAA 4W5OA 1U04A 1T2RA 3F73A 3HO1A 4NGDA 4F3TA 3MJ0A 4Z4FA 4W5TA 1SI3A 3HK2A 1Z25A 4OLBA 3O6EX 2FFLA 3DLHA 3HVRA 5KI6A 1Z26A 4NGGA 4OLAA 5JS1A 1R4KA 2QVWA 1VYNA 4Z4IA 4W5RA 1SI2A 4NGBA 4NH3A 1T2SA 4L1UA 3U1UA 4Z4EA 3HJFA 4NH6A 2DB9A 4NGFA 4L1PA 4Z4HA 4NH5A 4Z4CA 2BZEA 3DA5A 1R6ZA 3QIRA 5T7BA 3O7XA 2L5DA 2XFMA 4Z4GA 3O7VX 4NGCA 4KREA 3O3IX 4W5NA 3HM9A 2L5CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KRF A;  4W5Q A;  5JS2 A;  4NHA A;  4W5O A;  1T2R A;  4NGD A;  4F3T A;  3MJ0 A;  4Z4F A;  4W5T A;  1SI3 A;  4OLB A;  3O6E X;  2FFL A;  5KI6 A;  4NGG A;  5JS1 A;  4OLA A;  1R4K A;  2QVW A;  1VYN A;  4Z4I A;  4W5R A;  1SI2 A;  4NGB A;  4NH3 A;  1T2S A;  4Z4E A;  4NH6 A;  4NGF A;  4Z4H A;  4NH5 A;  4Z4C A;  3QIR A;  1R6Z A;  5T7B A;  4NGC A;  3O7X A;  2L5D A;  2XFM A;  4Z4G A;  4KRE A;  3O3I X;  4W5N A;  3O7V X;  2L5C A; 
#chains in the Genus database with same CATH topology
 4KRF A;  3DLB A;  4W5Q A;  5JS2 A;  4NHA A;  4W5O A;  1U04 A;  1T2R A;  3F73 A;  3HO1 A;  4NGD A;  4F3T A;  3MJ0 A;  4Z4F A;  4W5T A;  1SI3 A;  3HK2 A;  1Z25 A;  4OLB A;  3O6E X;  2FFL A;  3DLH A;  3HVR A;  5KI6 A;  1Z26 A;  4NGG A;  4OLA A;  5JS1 A;  1R4K A;  2QVW A;  1VYN A;  4Z4I A;  4W5R A;  1SI2 A;  4NGB A;  4NH3 A;  1T2S A;  4L1U A;  3U1U A;  4Z4E A;  3HJF A;  4NH6 A;  2DB9 A;  4NGF A;  4L1P A;  4Z4H A;  4NH5 A;  4Z4C A;  2BZE A;  3DA5 A;  1R6Z A;  3QIR A;  5T7B A;  3O7X A;  2L5D A;  2XFM A;  4Z4G A;  3O7V X;  4NGC A;  4KRE A;  3O3I X;  4W5N A;  3HM9 A;  2L5C A; 
#chains in the Genus database with same CATH homology
 4KRF A;  3DLB A;  4W5Q A;  5JS2 A;  4NHA A;  4W5O A;  1U04 A;  1T2R A;  3F73 A;  3HO1 A;  4NGD A;  4F3T A;  3MJ0 A;  4Z4F A;  4W5T A;  1SI3 A;  3HK2 A;  1Z25 A;  4OLB A;  3O6E X;  2FFL A;  3DLH A;  3HVR A;  5KI6 A;  1Z26 A;  4NGG A;  4OLA A;  5JS1 A;  1R4K A;  2QVW A;  1VYN A;  4Z4I A;  4W5R A;  1SI2 A;  4NGB A;  4NH3 A;  1T2S A;  4L1U A;  3U1U A;  4Z4E A;  3HJF A;  4NH6 A;  2DB9 A;  4NGF A;  4L1P A;  4Z4H A;  4NH5 A;  4Z4C A;  2BZE A;  3DA5 A;  1R6Z A;  3QIR A;  5T7B A;  3O7X A;  2L5D A;  2XFM A;  4Z4G A;  3O7V X;  4NGC A;  4KRE A;  3O3I X;  4W5N A;  3HM9 A;  2L5C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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