4NGDA

Structure of human dicer platform-paz-connector helix cassette in complex with 12-mer sirna having 5'-p and uu-3' ends (1.95 angstrom resolution)
Total Genus 69
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
298
structure length
280
Chain Sequence
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKPALAYCVLPLNVVSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 69
structure length 280
sequence length 298
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4ngdA02
4Z4FA 4NH6A 3O3IX 2FFLA 4NH3A 4W5NA 4W5OA 4W5QA 2XFMA 3O6EX 5T7BA 2L5DA 4NGBA 4NH5A 4W5RA 3QIRA 4Z4CA 4NHAA 4NGDA 4OLAA 4Z4GA 4KREA 3O7XA 1SI3A 1T2SA 4Z4IA 4F3TA 1R6ZA 4Z4EA 5JS2A 4Z4HA 1R4KA 1VYNA 5JS1A 4NGGA 1T2RA 4NGCA 4NGFA 4KRFA 2QVWA 4OLBA 3O7VX 3MJ0A 4W5TA 1SI2A 2L5CA 5KI6A
chains in the Genus database with same CATH superfamily
4Z4FA 4NH6A 3O3IX 2FFLA 4NH3A 3HJFA 4W5NA 4W5OA 4W5QA 2XFMA 3O6EX 5T7BA 2L5DA 4NGBA 4NH5A 4L1PA 1Z25A 4W5RA 3QIRA 4Z4CA 4NHAA 4NGDA 3DA5A 4OLAA 2DB9A 4Z4GA 3DLHA 4KREA 3O7XA 1Z26A 1SI3A 1T2SA 3F73A 4Z4IA 3HM9A 3HO1A 1R6ZA 4F3TA 3HVRA 2BZEA 4Z4EA 5JS2A 4Z4HA 1R4KA 1VYNA 3DLBA 4L1UA 4NGGA 1T2RA 5JS1A 4NGCA 4NGFA 4KRFA 3HK2A 2QVWA 4OLBA 3O7VX 3U1UA 3MJ0A 4W5TA 1U04A 1SI2A 2L5CA 5KI6A
chains in the Genus database with same CATH topology
4Z4FA 4NH6A 3O3IX 2FFLA 4NH3A 3HJFA 4W5NA 4W5OA 4W5QA 2XFMA 3O6EX 5T7BA 2L5DA 4NGBA 4NH5A 4L1PA 1Z25A 4W5RA 3QIRA 4Z4CA 4NHAA 4NGDA 3DA5A 4OLAA 2DB9A 4Z4GA 3DLHA 4KREA 3O7XA 1Z26A 1SI3A 1T2SA 3F73A 4Z4IA 3HM9A 3HO1A 1R6ZA 4F3TA 3HVRA 2BZEA 4Z4EA 5JS2A 4Z4HA 1R4KA 1VYNA 3DLBA 4L1UA 4NGGA 1T2RA 5JS1A 4NGCA 4NGFA 4KRFA 3HK2A 2QVWA 4OLBA 3O7VX 3U1UA 3MJ0A 4W5TA 1U04A 1SI2A 2L5CA 5KI6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z4F A;  4NH6 A;  3O3I X;  2FFL A;  4NH3 A;  4W5N A;  4W5O A;  4W5Q A;  2XFM A;  3O6E X;  5T7B A;  2L5D A;  4NGB A;  4NH5 A;  4W5R A;  3QIR A;  4Z4C A;  4NHA A;  4NGD A;  4OLA A;  4Z4G A;  4KRE A;  3O7X A;  1SI3 A;  1T2S A;  4Z4I A;  4F3T A;  1R6Z A;  4Z4E A;  5JS2 A;  4Z4H A;  1R4K A;  1VYN A;  5JS1 A;  4NGG A;  1T2R A;  4NGC A;  4NGF A;  4KRF A;  2QVW A;  4OLB A;  3O7V X;  3MJ0 A;  4W5T A;  1SI2 A;  2L5C A;  5KI6 A; 
#chains in the Genus database with same CATH topology
 4Z4F A;  4NH6 A;  3O3I X;  2FFL A;  4NH3 A;  3HJF A;  4W5N A;  4W5O A;  4W5Q A;  2XFM A;  3O6E X;  5T7B A;  2L5D A;  4NGB A;  4NH5 A;  4L1P A;  1Z25 A;  4W5R A;  3QIR A;  4Z4C A;  4NHA A;  4NGD A;  3DA5 A;  4OLA A;  2DB9 A;  4Z4G A;  3DLH A;  4KRE A;  3O7X A;  1Z26 A;  1SI3 A;  1T2S A;  3F73 A;  4Z4I A;  3HM9 A;  3HO1 A;  1R6Z A;  4F3T A;  3HVR A;  2BZE A;  4Z4E A;  5JS2 A;  4Z4H A;  1R4K A;  1VYN A;  3DLB A;  4L1U A;  4NGG A;  1T2R A;  5JS1 A;  4NGC A;  4NGF A;  4KRF A;  3HK2 A;  2QVW A;  4OLB A;  3O7V X;  3U1U A;  3MJ0 A;  4W5T A;  1U04 A;  1SI2 A;  2L5C A;  5KI6 A; 
#chains in the Genus database with same CATH homology
 4Z4F A;  4NH6 A;  3O3I X;  2FFL A;  4NH3 A;  3HJF A;  4W5N A;  4W5O A;  4W5Q A;  2XFM A;  3O6E X;  5T7B A;  2L5D A;  4NGB A;  4NH5 A;  4L1P A;  1Z25 A;  4W5R A;  3QIR A;  4Z4C A;  4NHA A;  4NGD A;  3DA5 A;  4OLA A;  2DB9 A;  4Z4G A;  3DLH A;  4KRE A;  3O7X A;  1Z26 A;  1SI3 A;  1T2S A;  3F73 A;  4Z4I A;  3HM9 A;  3HO1 A;  1R6Z A;  4F3T A;  3HVR A;  2BZE A;  4Z4E A;  5JS2 A;  4Z4H A;  1R4K A;  1VYN A;  3DLB A;  4L1U A;  4NGG A;  1T2R A;  5JS1 A;  4NGC A;  4NGF A;  4KRF A;  3HK2 A;  2QVW A;  4OLB A;  3O7V X;  3U1U A;  3MJ0 A;  4W5T A;  1U04 A;  1SI2 A;  2L5C A;  5KI6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...