4NH6A

Structure of human dicer platform-paz-connector helix cassette in complex with 15-mer sirna having 5'-puuu and uu-3' ends (2.55 angstrom resolution)
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
299
structure length
272
Chain Sequence
DQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEAYCVLPLNVVTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/rna
source organism Homo sapiens
publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule keywords Endoribonuclease Dicer
total genus 68
structure length 272
sequence length 299
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4nh6A02
2L5DA 4F3TA 3QIRA 2XFMA 2L5CA 1SI2A 4OLAA 4Z4FA 3O3IX 3O7VX 4NH6A 4W5TA 3O7XA 4KRFA 1T2SA 5JS1A 4KREA 4NH3A 2QVWA 1R4KA 1VYNA 4W5RA 5T7BA 2FFLA 4W5QA 5KI6A 1T2RA 4Z4CA 4Z4IA 1SI3A 4NGFA 5JS2A 4W5NA 3O6EX 4Z4EA 3MJ0A 4NGGA 4NGDA 4NHAA 4NH5A 4NGBA 4W5OA 4OLBA 1R6ZA 4Z4HA 4Z4GA 4NGCA
chains in the Genus database with same CATH superfamily
2L5DA 4F3TA 3QIRA 2XFMA 2L5CA 1SI2A 4OLAA 3HM9A 4Z4FA 3O3IX 3O7VX 3DA5A 4L1UA 4NH6A 3HJFA 4W5TA 3O7XA 4KRFA 1T2SA 5JS1A 3HVRA 4KREA 3F73A 4NH3A 2QVWA 1R4KA 4Z4GA 3U1UA 3DLHA 1VYNA 3HK2A 1Z26A 2BZEA 4W5RA 5T7BA 2FFLA 4W5QA 5KI6A 1T2RA 4Z4CA 4Z4IA 1SI3A 4NGFA 5JS2A 4W5NA 3O6EX 4Z4EA 3MJ0A 4L1PA 3HO1A 4NHAA 4NGGA 1Z25A 4NH5A 4NGDA 4NGBA 4W5OA 1U04A 2DB9A 4OLBA 1R6ZA 4Z4HA 3DLBA 4NGCA
chains in the Genus database with same CATH topology
2L5DA 4F3TA 3QIRA 2XFMA 2L5CA 1SI2A 4OLAA 3HM9A 4Z4FA 3O3IX 3O7VX 3DA5A 4L1UA 4NH6A 3HJFA 4W5TA 3O7XA 4KRFA 1T2SA 5JS1A 3HVRA 4KREA 3F73A 4NH3A 2QVWA 1R4KA 4Z4GA 3U1UA 3DLHA 1VYNA 3HK2A 1Z26A 2BZEA 4W5RA 5T7BA 2FFLA 4W5QA 5KI6A 1T2RA 4Z4CA 4Z4IA 1SI3A 4NGFA 5JS2A 4W5NA 3O6EX 4Z4EA 3MJ0A 4L1PA 3HO1A 4NHAA 4NGGA 1Z25A 4NH5A 4NGDA 4NGBA 4W5OA 1U04A 2DB9A 4OLBA 1R6ZA 4Z4HA 3DLBA 4NGCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L5D A;  4F3T A;  3QIR A;  2XFM A;  2L5C A;  1SI2 A;  4OLA A;  4Z4F A;  3O3I X;  3O7V X;  4NH6 A;  4W5T A;  3O7X A;  4KRF A;  1T2S A;  5JS1 A;  4KRE A;  4NH3 A;  2QVW A;  1R4K A;  1VYN A;  4W5R A;  5T7B A;  2FFL A;  4W5Q A;  5KI6 A;  1T2R A;  4Z4C A;  4Z4I A;  1SI3 A;  4NGF A;  5JS2 A;  4W5N A;  3O6E X;  4Z4E A;  3MJ0 A;  4NGG A;  4NGD A;  4NHA A;  4NH5 A;  4NGB A;  4W5O A;  4OLB A;  1R6Z A;  4Z4H A;  4Z4G A;  4NGC A; 
#chains in the Genus database with same CATH topology
 2L5D A;  4F3T A;  3QIR A;  2XFM A;  2L5C A;  1SI2 A;  4OLA A;  3HM9 A;  4Z4F A;  3O3I X;  3O7V X;  3DA5 A;  4L1U A;  4NH6 A;  3HJF A;  4W5T A;  3O7X A;  4KRF A;  1T2S A;  5JS1 A;  3HVR A;  4KRE A;  3F73 A;  4NH3 A;  2QVW A;  1R4K A;  4Z4G A;  3U1U A;  3DLH A;  1VYN A;  3HK2 A;  1Z26 A;  2BZE A;  4W5R A;  5T7B A;  2FFL A;  4W5Q A;  5KI6 A;  1T2R A;  4Z4C A;  4Z4I A;  1SI3 A;  4NGF A;  5JS2 A;  4W5N A;  3O6E X;  4Z4E A;  3MJ0 A;  4L1P A;  3HO1 A;  4NHA A;  4NGG A;  1Z25 A;  4NH5 A;  4NGD A;  4NGB A;  4W5O A;  1U04 A;  2DB9 A;  4OLB A;  1R6Z A;  4Z4H A;  3DLB A;  4NGC A; 
#chains in the Genus database with same CATH homology
 2L5D A;  4F3T A;  3QIR A;  2XFM A;  2L5C A;  1SI2 A;  4OLA A;  3HM9 A;  4Z4F A;  3O3I X;  3O7V X;  3DA5 A;  4L1U A;  4NH6 A;  3HJF A;  4W5T A;  3O7X A;  4KRF A;  1T2S A;  5JS1 A;  3HVR A;  4KRE A;  3F73 A;  4NH3 A;  2QVW A;  1R4K A;  4Z4G A;  3U1U A;  3DLH A;  1VYN A;  3HK2 A;  1Z26 A;  2BZE A;  4W5R A;  5T7B A;  2FFL A;  4W5Q A;  5KI6 A;  1T2R A;  4Z4C A;  4Z4I A;  1SI3 A;  4NGF A;  5JS2 A;  4W5N A;  3O6E X;  4Z4E A;  3MJ0 A;  4L1P A;  3HO1 A;  4NHA A;  4NGG A;  1Z25 A;  4NH5 A;  4NGD A;  4NGB A;  4W5O A;  1U04 A;  2DB9 A;  4OLB A;  1R6Z A;  4Z4H A;  3DLB A;  4NGC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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