4NHAA

Structure of human dicer platform-paz-connector helix cassette in complex with 16-mer sirna having 5'-p and uu-3' ends (3.4 angstrom resolution)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
294
structure length
234
Chain Sequence
LYVIGMVLTTPLPDELRKLYPPEDTTRCFGILTAKPIPQIPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLSAYCVLPLNVTLDIDFKFMEDIEKSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 43
structure length 234
sequence length 294
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4nhaA02
4W5TA 3O3IX 4W5QA 5JS2A 4NGGA 4W5NA 4Z4FA 1T2SA 5KI6A 1SI3A 4NGBA 4Z4IA 4KREA 3MJ0A 2XFMA 4Z4GA 4NH3A 2QVWA 2L5CA 5T7BA 2FFLA 4NGCA 4Z4EA 4NGFA 1SI2A 3O7VX 4Z4HA 5JS1A 2L5DA 4F3TA 3O7XA 4NHAA 4KRFA 1R4KA 4OLAA 3QIRA 4Z4CA 4NGDA 1R6ZA 4W5OA 4NH6A 3O6EX 4OLBA 4NH5A 4W5RA 1VYNA 1T2RA
chains in the Genus database with same CATH superfamily
4W5TA 3O3IX 4W5QA 5JS2A 4NGGA 4W5NA 4Z4FA 1U04A 3DLHA 1T2SA 5KI6A 1SI3A 4L1UA 4NGBA 3HJFA 4Z4IA 4KREA 3MJ0A 2XFMA 3HO1A 3HVRA 3DLBA 4Z4GA 3HK2A 3DA5A 4NH3A 2QVWA 2L5CA 1Z25A 5T7BA 2FFLA 3F73A 4Z4EA 4NGFA 4NGCA 2DB9A 1SI2A 3O7VX 4Z4HA 5JS1A 3HM9A 2L5DA 4F3TA 3O7XA 4NHAA 1Z26A 4KRFA 1R4KA 4OLAA 3U1UA 3QIRA 4Z4CA 2BZEA 4NGDA 1R6ZA 4W5OA 4NH6A 4L1PA 3O6EX 4OLBA 4NH5A 4W5RA 1VYNA 1T2RA
chains in the Genus database with same CATH topology
4W5TA 3O3IX 4W5QA 5JS2A 4NGGA 4W5NA 4Z4FA 1U04A 3DLHA 1T2SA 5KI6A 1SI3A 4L1UA 4NGBA 3HJFA 4Z4IA 4KREA 3MJ0A 2XFMA 3HO1A 3HVRA 3DLBA 4Z4GA 3HK2A 3DA5A 4NH3A 2QVWA 2L5CA 1Z25A 5T7BA 2FFLA 3F73A 4Z4EA 4NGFA 4NGCA 2DB9A 1SI2A 3O7VX 4Z4HA 5JS1A 3HM9A 2L5DA 4F3TA 3O7XA 4NHAA 1Z26A 4KRFA 1R4KA 4OLAA 3U1UA 3QIRA 4Z4CA 2BZEA 4NGDA 1R6ZA 4W5OA 4NH6A 4L1PA 3O6EX 4OLBA 4NH5A 4W5RA 1VYNA 1T2RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4W5T A;  3O3I X;  4W5Q A;  5JS2 A;  4NGG A;  4W5N A;  4Z4F A;  1T2S A;  5KI6 A;  1SI3 A;  4NGB A;  4Z4I A;  4KRE A;  3MJ0 A;  2XFM A;  4Z4G A;  4NH3 A;  2QVW A;  2L5C A;  5T7B A;  2FFL A;  4NGC A;  4Z4E A;  4NGF A;  1SI2 A;  3O7V X;  4Z4H A;  5JS1 A;  2L5D A;  4F3T A;  3O7X A;  4NHA A;  4KRF A;  1R4K A;  4OLA A;  3QIR A;  4Z4C A;  4NGD A;  1R6Z A;  4W5O A;  4NH6 A;  3O6E X;  4OLB A;  4NH5 A;  4W5R A;  1VYN A;  1T2R A; 
#chains in the Genus database with same CATH topology
 4W5T A;  3O3I X;  4W5Q A;  5JS2 A;  4NGG A;  4W5N A;  4Z4F A;  1U04 A;  3DLH A;  1T2S A;  5KI6 A;  1SI3 A;  4L1U A;  4NGB A;  3HJF A;  4Z4I A;  4KRE A;  3MJ0 A;  2XFM A;  3HO1 A;  3HVR A;  3DLB A;  4Z4G A;  3HK2 A;  3DA5 A;  4NH3 A;  2QVW A;  2L5C A;  1Z25 A;  5T7B A;  2FFL A;  3F73 A;  4Z4E A;  4NGF A;  4NGC A;  2DB9 A;  1SI2 A;  3O7V X;  4Z4H A;  5JS1 A;  3HM9 A;  2L5D A;  4F3T A;  3O7X A;  4NHA A;  1Z26 A;  4KRF A;  1R4K A;  4OLA A;  3U1U A;  3QIR A;  4Z4C A;  2BZE A;  4NGD A;  1R6Z A;  4W5O A;  4NH6 A;  4L1P A;  3O6E X;  4OLB A;  4NH5 A;  4W5R A;  1VYN A;  1T2R A; 
#chains in the Genus database with same CATH homology
 4W5T A;  3O3I X;  4W5Q A;  5JS2 A;  4NGG A;  4W5N A;  4Z4F A;  1U04 A;  3DLH A;  1T2S A;  5KI6 A;  1SI3 A;  4L1U A;  4NGB A;  3HJF A;  4Z4I A;  4KRE A;  3MJ0 A;  2XFM A;  3HO1 A;  3HVR A;  3DLB A;  4Z4G A;  3HK2 A;  3DA5 A;  4NH3 A;  2QVW A;  2L5C A;  1Z25 A;  5T7B A;  2FFL A;  3F73 A;  4Z4E A;  4NGF A;  4NGC A;  2DB9 A;  1SI2 A;  3O7V X;  4Z4H A;  5JS1 A;  3HM9 A;  2L5D A;  4F3T A;  3O7X A;  4NHA A;  1Z26 A;  4KRF A;  1R4K A;  4OLA A;  3U1U A;  3QIR A;  4Z4C A;  2BZE A;  4NGD A;  1R6Z A;  4W5O A;  4NH6 A;  4L1P A;  3O6E X;  4OLB A;  4NH5 A;  4W5R A;  1VYN A;  1T2R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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