4WLWA

Crystal structure of the ag(i) (activator) form of e. coli cuer, a copper efflux regulator, bound to copa promoter dna
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
130
structure length
130
Chain Sequence
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Escherichia coli
molecule keywords HTH-type transcriptional regulator CueR
total genus 46
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 4wlwA00
2ZHHA 2DG6A 5I44A 5D90A 3D71A 1Q06A 3D70A 1R8EA 1Q09A 5D8CA 3Q3DA 3Q5PA 5E01A 1EXJA 4J2NA 4WLWA 4R24B 3Q1MA 4R4EA 4WLSA 3UCSA 1EXIA 2VZ4A 3Q5RA 4R22B 1R8DA 3D6ZA 1Q08A 3HH0A 2JMLA 3GPVA 3Q2YA 3Q5SA 1Q07A 3D6YA 2ZHGA 1JBGA 1Q05A 3IAOA 5I41B 3QAOA 3GP4A 1Q0AA
chains in the Genus database with same CATH superfamily
2ZHHA 1Y6UA 2KVVA 4LHFA 2DG6A 5I44A 1LX8A 5D90A 3D71A 2OG0A 1Q06A 3EZ9A 3D70A 1R8EA 1Q09A 5D8CA 3Q3DA 3Q5PA 3EZ7A 5E01A 1PM6A 1EXJA 4J2NA 3EZ6A 4WLWA 4R24B 3Q1MA 4R4EA 4WLSA 3UCSA 4DCZA 1EXIA 3EZFA 2VZ4A 3Q5RA 4R22B 1R8DA 3D6ZA 2IEFA 1Q08A 3HH0A 2JMLA 3GPVA 3Q2YA 3Q5SA 1Q07A 1RH6A 2ZHGA 3D6YA 1JBGA 1Q05A 3IAOA 5I41B 3QAOA 3EZ2A 3GP4A 1Q0AA
chains in the Genus database with same CATH topology
2ZHHA 1Y6UA 2KVVA 4LHFA 2DG6A 5I44A 1LX8A 5D90A 3D71A 2OG0A 1Q06A 3EZ9A 3D70A 1R8EA 1Q09A 5D8CA 3Q3DA 3Q5PA 3EZ7A 5E01A 1PM6A 1EXJA 4J2NA 3EZ6A 4WLWA 4R24B 3Q1MA 4R4EA 4WLSA 3UCSA 4DCZA 1EXIA 3EZFA 2VZ4A 3Q5RA 4R22B 1R8DA 3D6ZA 2IEFA 1Q08A 3HH0A 2JMLA 3GPVA 3Q2YA 3Q5SA 1Q07A 1RH6A 2ZHGA 3D6YA 1JBGA 1Q05A 3IAOA 5I41B 3QAOA 3EZ2A 3GP4A 1Q0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZHH A;  2DG6 A;  5I44 A;  5D90 A;  3D71 A;  1Q06 A;  3D70 A;  1R8E A;  1Q09 A;  5D8C A;  3Q3D A;  3Q5P A;  5E01 A;  1EXJ A;  4J2N A;  4WLW A;  4R24 B;  3Q1M A;  4R4E A;  4WLS A;  3UCS A;  1EXI A;  2VZ4 A;  3Q5R A;  4R22 B;  1R8D A;  3D6Z A;  1Q08 A;  3HH0 A;  2JML A;  3GPV A;  3Q2Y A;  3Q5S A;  1Q07 A;  3D6Y A;  2ZHG A;  1JBG A;  1Q05 A;  3IAO A;  5I41 B;  3QAO A;  3GP4 A;  1Q0A A; 
#chains in the Genus database with same CATH topology
 2ZHH A;  1Y6U A;  2KVV A;  4LHF A;  2DG6 A;  5I44 A;  1LX8 A;  5D90 A;  3D71 A;  2OG0 A;  1Q06 A;  3EZ9 A;  3D70 A;  1R8E A;  1Q09 A;  5D8C A;  3Q3D A;  3Q5P A;  3EZ7 A;  5E01 A;  1PM6 A;  1EXJ A;  4J2N A;  3EZ6 A;  4WLW A;  4R24 B;  3Q1M A;  4R4E A;  4WLS A;  3UCS A;  4DCZ A;  1EXI A;  3EZF A;  2VZ4 A;  3Q5R A;  4R22 B;  1R8D A;  3D6Z A;  2IEF A;  1Q08 A;  3HH0 A;  2JML A;  3GPV A;  3Q2Y A;  3Q5S A;  1Q07 A;  1RH6 A;  2ZHG A;  3D6Y A;  1JBG A;  1Q05 A;  3IAO A;  5I41 B;  3QAO A;  3EZ2 A;  3GP4 A;  1Q0A A; 
#chains in the Genus database with same CATH homology
 2ZHH A;  1Y6U A;  2KVV A;  4LHF A;  2DG6 A;  5I44 A;  1LX8 A;  5D90 A;  3D71 A;  2OG0 A;  1Q06 A;  3EZ9 A;  3D70 A;  1R8E A;  1Q09 A;  5D8C A;  3Q3D A;  3Q5P A;  3EZ7 A;  5E01 A;  1PM6 A;  1EXJ A;  4J2N A;  3EZ6 A;  4WLW A;  4R24 B;  3Q1M A;  4R4E A;  4WLS A;  3UCS A;  4DCZ A;  1EXI A;  3EZF A;  2VZ4 A;  3Q5R A;  4R22 B;  1R8D A;  3D6Z A;  2IEF A;  1Q08 A;  3HH0 A;  2JML A;  3GPV A;  3Q2Y A;  3Q5S A;  1Q07 A;  1RH6 A;  2ZHG A;  3D6Y A;  1JBG A;  1Q05 A;  3IAO A;  5I41 B;  3QAO A;  3EZ2 A;  3GP4 A;  1Q0A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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