4WLWA

Crystal structure of the ag(i) (activator) form of e. coli cuer, a copper efflux regulator, bound to copa promoter dna
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
130
structure length
130
Chain Sequence
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/dna
source organism Escherichia coli
publication title TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
pubmed doi rcsb
molecule keywords HTH-type transcriptional regulator CueR
total genus 46
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 4wlwA00
1Q07A 1Q06A 4R4EA 1JBGA 3D71A 3Q5RA 2JMLA 5D8CA 3GP4A 2ZHGA 3Q1MA 2DG6A 3GPVA 5I44A 1Q05A 5D90A 4J2NA 2VZ4A 3QAOA 3Q5PA 4R24B 3IAOA 5E01A 4R22B 3Q3DA 1Q08A 3D6ZA 1EXIA 3Q2YA 3UCSA 4WLWA 4WLSA 2ZHHA 1R8EA 1R8DA 1Q0AA 1Q09A 3D6YA 3Q5SA 3D70A 1EXJA 5I41B 3HH0A
chains in the Genus database with same CATH superfamily
1Q07A 1Q06A 4R4EA 1PM6A 1JBGA 3D71A 3Q5RA 2JMLA 1LX8A 5D8CA 3GP4A 3EZ7A 2ZHGA 3Q1MA 2IEFA 1Y6UA 2DG6A 3GPVA 5I44A 1Q05A 5D90A 4J2NA 2VZ4A 3QAOA 3Q5PA 4R24B 3IAOA 5E01A 3HH0A 4R22B 3EZ9A 4DCZA 3Q3DA 1Q08A 3D6ZA 3EZ6A 1EXIA 3Q2YA 3EZFA 3UCSA 4WLWA 1RH6A 4WLSA 2ZHHA 1R8EA 1R8DA 1Q0AA 1Q09A 3D6YA 3Q5SA 3EZ2A 3D70A 4LHFA 1EXJA 2OG0A 5I41B 2KVVA
chains in the Genus database with same CATH topology
1Q07A 1Q06A 4R4EA 1PM6A 1JBGA 3D71A 3Q5RA 2JMLA 1LX8A 5D8CA 3GP4A 3EZ7A 2ZHGA 3Q1MA 2IEFA 1Y6UA 2DG6A 3GPVA 5I44A 1Q05A 5D90A 4J2NA 2VZ4A 3QAOA 3Q5PA 4R24B 3IAOA 5E01A 3HH0A 4R22B 3EZ9A 4DCZA 3Q3DA 1Q08A 3D6ZA 3EZ6A 1EXIA 3Q2YA 3EZFA 3UCSA 4WLWA 1RH6A 4WLSA 2ZHHA 1R8EA 1R8DA 1Q0AA 1Q09A 3D6YA 3Q5SA 3EZ2A 3D70A 4LHFA 1EXJA 2OG0A 5I41B 2KVVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Q07 A;  1Q06 A;  4R4E A;  1JBG A;  3D71 A;  3Q5R A;  2JML A;  5D8C A;  3GP4 A;  2ZHG A;  3Q1M A;  2DG6 A;  3GPV A;  5I44 A;  1Q05 A;  5D90 A;  4J2N A;  2VZ4 A;  3QAO A;  3Q5P A;  4R24 B;  3IAO A;  5E01 A;  4R22 B;  3Q3D A;  1Q08 A;  3D6Z A;  1EXI A;  3Q2Y A;  3UCS A;  4WLW A;  4WLS A;  2ZHH A;  1R8E A;  1R8D A;  1Q0A A;  1Q09 A;  3D6Y A;  3Q5S A;  3D70 A;  1EXJ A;  5I41 B;  3HH0 A; 
#chains in the Genus database with same CATH topology
 1Q07 A;  1Q06 A;  4R4E A;  1PM6 A;  1JBG A;  3D71 A;  3Q5R A;  2JML A;  1LX8 A;  5D8C A;  3GP4 A;  3EZ7 A;  2ZHG A;  3Q1M A;  2IEF A;  1Y6U A;  2DG6 A;  3GPV A;  5I44 A;  1Q05 A;  5D90 A;  4J2N A;  2VZ4 A;  3QAO A;  3Q5P A;  4R24 B;  3IAO A;  5E01 A;  3HH0 A;  4R22 B;  3EZ9 A;  4DCZ A;  3Q3D A;  1Q08 A;  3D6Z A;  3EZ6 A;  1EXI A;  3Q2Y A;  3EZF A;  3UCS A;  4WLW A;  1RH6 A;  4WLS A;  2ZHH A;  1R8E A;  1R8D A;  1Q0A A;  1Q09 A;  3D6Y A;  3Q5S A;  3EZ2 A;  3D70 A;  4LHF A;  1EXJ A;  2OG0 A;  5I41 B;  2KVV A; 
#chains in the Genus database with same CATH homology
 1Q07 A;  1Q06 A;  4R4E A;  1PM6 A;  1JBG A;  3D71 A;  3Q5R A;  2JML A;  1LX8 A;  5D8C A;  3GP4 A;  3EZ7 A;  2ZHG A;  3Q1M A;  2IEF A;  1Y6U A;  2DG6 A;  3GPV A;  5I44 A;  1Q05 A;  5D90 A;  4J2N A;  2VZ4 A;  3QAO A;  3Q5P A;  4R24 B;  3IAO A;  5E01 A;  3HH0 A;  4R22 B;  3EZ9 A;  4DCZ A;  3Q3D A;  1Q08 A;  3D6Z A;  3EZ6 A;  1EXI A;  3Q2Y A;  3EZF A;  3UCS A;  4WLW A;  1RH6 A;  4WLS A;  2ZHH A;  1R8E A;  1R8D A;  1Q0A A;  1Q09 A;  3D6Y A;  3Q5S A;  3EZ2 A;  3D70 A;  4LHF A;  1EXJ A;  2OG0 A;  5I41 B;  2KVV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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