4WLWA

Crystal structure of the ag(i) (activator) form of e. coli cuer, a copper efflux regulator, bound to copa promoter dna
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
130
structure length
130
Chain Sequence
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANACPGDDSADCPIIENLSGCC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title TRANSCRIPTION. Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
pubmed doi rcsb
molecule keywords HTH-type transcriptional regulator CueR
molecule tags Transcription/dna
source organism Escherichia coli
total genus 46
structure length 130
sequence length 130
ec nomenclature
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 4wlwA00
3HH0A 4R4EA 2ZHGA 1R8EA 4WLSA 3D6ZA 3GP4A 3Q5PA 5D90A 3Q5RA 1Q07A 4R22B 3D6YA 4R24B 5I44A 1Q0AA 1Q06A 5D8CA 3Q1MA 1EXJA 3QAOA 3Q3DA 3D71A 2DG6A 1EXIA 1Q08A 2ZHHA 4J2NA 3GPVA 3UCSA 3IAOA 5E01A 3Q2YA 1Q09A 3Q5SA 1Q05A 4WLWA 1JBGA 5I41B 2JMLA 2VZ4A 1R8DA 3D70A
chains in the Genus database with same CATH superfamily
4LHFA 3HH0A 1RH6A 1PM6A 4R4EA 2ZHGA 2KVVA 1R8EA 4WLSA 3D6ZA 3GP4A 3Q5PA 5D90A 3Q5RA 1Q07A 4R22B 3D6YA 3EZ9A 3EZFA 4R24B 5I44A 1Q0AA 1Q06A 5D8CA 3Q1MA 1EXJA 3QAOA 3Q3DA 3D71A 4DCZA 2DG6A 1EXIA 2OG0A 1Q08A 2ZHHA 1Y6UA 3GPVA 4J2NA 3UCSA 1LX8A 3IAOA 5E01A 3Q2YA 1Q09A 3Q5SA 1Q05A 3EZ6A 1JBGA 4WLWA 2IEFA 3EZ7A 5I41B 2JMLA 2VZ4A 1R8DA 3D70A 3EZ2A
chains in the Genus database with same CATH topology
4LHFA 3HH0A 1RH6A 1PM6A 4R4EA 2ZHGA 2KVVA 1R8EA 4WLSA 3D6ZA 3GP4A 3Q5PA 5D90A 3Q5RA 1Q07A 4R22B 3D6YA 3EZ9A 3EZFA 4R24B 5I44A 1Q0AA 1Q06A 5D8CA 3Q1MA 1EXJA 3QAOA 3Q3DA 3D71A 4DCZA 2DG6A 1EXIA 2OG0A 1Q08A 2ZHHA 1Y6UA 3GPVA 4J2NA 3UCSA 1LX8A 3IAOA 5E01A 3Q2YA 1Q09A 3Q5SA 1Q05A 3EZ6A 1JBGA 4WLWA 2IEFA 3EZ7A 5I41B 2JMLA 2VZ4A 1R8DA 3D70A 3EZ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HH0 A;  4R4E A;  2ZHG A;  1R8E A;  4WLS A;  3D6Z A;  3GP4 A;  3Q5P A;  5D90 A;  3Q5R A;  1Q07 A;  4R22 B;  3D6Y A;  4R24 B;  5I44 A;  1Q0A A;  1Q06 A;  5D8C A;  3Q1M A;  1EXJ A;  3QAO A;  3Q3D A;  3D71 A;  2DG6 A;  1EXI A;  1Q08 A;  2ZHH A;  4J2N A;  3GPV A;  3UCS A;  3IAO A;  5E01 A;  3Q2Y A;  1Q09 A;  3Q5S A;  1Q05 A;  4WLW A;  1JBG A;  5I41 B;  2JML A;  2VZ4 A;  1R8D A;  3D70 A; 
#chains in the Genus database with same CATH topology
 4LHF A;  3HH0 A;  1RH6 A;  1PM6 A;  4R4E A;  2ZHG A;  2KVV A;  1R8E A;  4WLS A;  3D6Z A;  3GP4 A;  3Q5P A;  5D90 A;  3Q5R A;  1Q07 A;  4R22 B;  3D6Y A;  3EZ9 A;  3EZF A;  4R24 B;  5I44 A;  1Q0A A;  1Q06 A;  5D8C A;  3Q1M A;  1EXJ A;  3QAO A;  3Q3D A;  3D71 A;  4DCZ A;  2DG6 A;  1EXI A;  2OG0 A;  1Q08 A;  2ZHH A;  1Y6U A;  3GPV A;  4J2N A;  3UCS A;  1LX8 A;  3IAO A;  5E01 A;  3Q2Y A;  1Q09 A;  3Q5S A;  1Q05 A;  3EZ6 A;  1JBG A;  4WLW A;  2IEF A;  3EZ7 A;  5I41 B;  2JML A;  2VZ4 A;  1R8D A;  3D70 A;  3EZ2 A; 
#chains in the Genus database with same CATH homology
 4LHF A;  3HH0 A;  1RH6 A;  1PM6 A;  4R4E A;  2ZHG A;  2KVV A;  1R8E A;  4WLS A;  3D6Z A;  3GP4 A;  3Q5P A;  5D90 A;  3Q5R A;  1Q07 A;  4R22 B;  3D6Y A;  3EZ9 A;  3EZF A;  4R24 B;  5I44 A;  1Q0A A;  1Q06 A;  5D8C A;  3Q1M A;  1EXJ A;  3QAO A;  3Q3D A;  3D71 A;  4DCZ A;  2DG6 A;  1EXI A;  2OG0 A;  1Q08 A;  2ZHH A;  1Y6U A;  3GPV A;  4J2N A;  3UCS A;  1LX8 A;  3IAO A;  5E01 A;  3Q2Y A;  1Q09 A;  3Q5S A;  1Q05 A;  3EZ6 A;  1JBG A;  4WLW A;  2IEF A;  3EZ7 A;  5I41 B;  2JML A;  2VZ4 A;  1R8D A;  3D70 A;  3EZ2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...