4D2GA

Crystal structure of human pcna in complex with p15 peptide
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
258
structure length
258
Chain Sequence
GPHMFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
pubmed doi rcsb
molecule keywords PROLIFERATING CELL NUCLEAR ANTIGEN
molecule tags Transcription
source organism Homo sapiens
total genus 60
structure length 258
sequence length 258
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4d2gA00
5DAIA 3LX1A 5AUJA 1UD9A 1U76A 2IX2A 2OD8A 1B8HA 3A1JB 3VKXA 3V60B 3GPNA 2HIKB 3HSLX 3GGRC 1UL1A 3HI8A 3P83A 1DMLA 3WGWA 2IO4B 3G65C 5IWDA 2ZVWA 5DA7A 1VYMA 2ZVKA 2NTIC 3A2FB 5HACA 3K4XA 3GPMA 2IX2C 1U7BA 1RXMA 3IFVA 1RXZA 1AXCA 1SXJF 1RWZA 4HK1A 5E0TA 4D2GA 1T6LA 2HIKA 3I2MX 1GE8A 4CS5A 5H0TA 3U5ZF 1PLRA 3V62B 1IZ5A 3GGRB 3AIXB 2IJXA 3G65B 1YYPA 3P87A 2HIIB 3FDSD 2IZOC 1W60A 2NTIB 2ZVVA 3A1JA 1PLQA 1ISQA 5B7OA 5IXAA 4YHRA 3U61F 5JNED 2IO4A 5E0VA 5A6DA 5IY4A 3AIXA 1B77A 3LX2A 2AWAA 3FDSC 3U60F 2ZVMA 2HIIA 5E0UA 5CFKA 4L6PA 2NTIA 4RJFA 3AIZA 4L60A 3A1JC 1CZDA 3V61B 2Z0LA 2HIKC 2IZOB 2IX2B 4ZTDA 1VYJA 2ZVLA 4TR6A 2AVTA 1IZ4A 3P91A 3TBLA 3GGRA 2HIIC 3F1WA 3G65A 3AIZC
chains in the Genus database with same CATH superfamily
5DAIA 3LX1A 5AUJA 1UD9A 1U76A 2IX2A 2OD8A 1B8HA 3A1JB 3VKXA 3V60B 3GPNA 2HIKB 3HSLX 3GGRC 1UL1A 3HI8A 3P83A 1DMLA 3WGWA 2IO4B 3G65C 5IWDA 2ZVWA 5DA7A 1VYMA 2ZVKA 2NTIC 3A2FB 5HACA 3K4XA 3GPMA 2IX2C 1U7BA 1RXMA 3IFVA 1RXZA 1AXCA 1SXJF 1RWZA 4HK1A 5E0TA 4D2GA 1T6LA 2HIKA 3I2MX 1GE8A 4CS5A 5H0TA 3U5ZF 1PLRA 3V62B 1IZ5A 3GGRB 3AIXB 2IJXA 3G65B 1YYPA 3P87A 2HIIB 3FDSD 2IZOC 1W60A 2NTIB 2ZVVA 3A1JA 1PLQA 1ISQA 5B7OA 5IXAA 4YHRA 3U61F 5JNED 2IO4A 5E0VA 5A6DA 5IY4A 3AIXA 1B77A 3LX2A 2AWAA 3FDSC 3U60F 2ZVMA 2HIIA 5E0UA 5CFKA 4L6PA 2NTIA 4RJFA 3AIZA 4L60A 3A1JC 1CZDA 3V61B 2Z0LA 2HIKC 2IZOB 2IX2B 4ZTDA 1VYJA 2ZVLA 4TR6A 2AVTA 1IZ4A 3P91A 3TBLA 3GGRA 2HIIC 3F1WA 3G65A 3AIZC
chains in the Genus database with same CATH topology
5DAIA 3LX1A 5AUJA 1UD9A 1U76A 2IX2A 2OD8A 1B8HA 3A1JB 3VKXA 3V60B 3GPNA 2HIKB 3HSLX 3GGRC 1UL1A 3HI8A 3P83A 1DMLA 3WGWA 2IO4B 3G65C 5IWDA 2ZVWA 5DA7A 1VYMA 2ZVKA 2NTIC 3A2FB 5HACA 3K4XA 3GPMA 2IX2C 1U7BA 1RXMA 3IFVA 1RXZA 1AXCA 1SXJF 1RWZA 4HK1A 5E0TA 4D2GA 1T6LA 2HIKA 3I2MX 1GE8A 4CS5A 5H0TA 3U5ZF 1PLRA 3V62B 1IZ5A 3GGRB 3AIXB 2IJXA 3G65B 1YYPA 3P87A 2HIIB 3FDSD 2IZOC 1W60A 2NTIB 2ZVVA 3A1JA 1PLQA 1ISQA 5B7OA 5IXAA 4YHRA 3U61F 5JNED 2IO4A 5E0VA 5A6DA 5IY4A 3AIXA 1B77A 3LX2A 2AWAA 3FDSC 3U60F 2ZVMA 2HIIA 5E0UA 5CFKA 4L6PA 2NTIA 4RJFA 3AIZA 4L60A 3A1JC 1CZDA 3V61B 2Z0LA 2HIKC 2IZOB 2IX2B 4ZTDA 1VYJA 2ZVLA 4TR6A 2AVTA 1IZ4A 3P91A 3TBLA 3GGRA 2HIIC 3F1WA 3G65A 3AIZC
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5DAI A;  3LX1 A;  5AUJ A;  1UD9 A;  1U76 A;  2IX2 A;  2OD8 A;  1B8H A;  3A1J B;  3VKX A;  3V60 B;  3GPN A;  2HIK B;  3HSL X;  3GGR C;  1UL1 A;  3HI8 A;  3P83 A;  1DML A;  3WGW A;  2IO4 B;  3G65 C;  5IWD A;  2ZVW A;  5DA7 A;  1VYM A;  2ZVK A;  2NTI C;  3A2F B;  5HAC A;  3K4X A;  3GPM A;  2IX2 C;  1U7B A;  1RXM A;  3IFV A;  1RXZ A;  1AXC A;  1SXJ F;  1RWZ A;  4HK1 A;  5E0T A;  4D2G A;  1T6L A;  2HIK A;  3I2M X;  1GE8 A;  4CS5 A;  5H0T A;  3U5Z F;  1PLR A;  3V62 B;  1IZ5 A;  3GGR B;  3AIX B;  2IJX A;  3G65 B;  1YYP A;  3P87 A;  2HII B;  3FDS D;  2IZO C;  1W60 A;  2NTI B;  2ZVV A;  3A1J A;  1PLQ A;  1ISQ A;  5B7O A;  5IXA A;  4YHR A;  3U61 F;  5JNE D;  2IO4 A;  5E0V A;  5A6D A;  5IY4 A;  3AIX A;  1B77 A;  3LX2 A;  2AWA A;  3FDS C;  3U60 F;  2ZVM A;  2HII A;  5E0U A;  5CFK A;  4L6P A;  2NTI A;  4RJF A;  3AIZ A;  4L60 A;  3A1J C;  1CZD A;  3V61 B;  2Z0L A;  2HIK C;  2IZO B;  2IX2 B;  4ZTD A;  1VYJ A;  2ZVL A;  4TR6 A;  2AVT A;  1IZ4 A;  3P91 A;  3TBL A;  3GGR A;  2HII C;  3F1W A;  3G65 A;  3AIZ C; 
#chains in the Genus database with same CATH topology
 5DAI A;  3LX1 A;  5AUJ A;  1UD9 A;  1U76 A;  2IX2 A;  2OD8 A;  1B8H A;  3A1J B;  3VKX A;  3V60 B;  3GPN A;  2HIK B;  3HSL X;  3GGR C;  1UL1 A;  3HI8 A;  3P83 A;  1DML A;  3WGW A;  2IO4 B;  3G65 C;  5IWD A;  2ZVW A;  5DA7 A;  1VYM A;  2ZVK A;  2NTI C;  3A2F B;  5HAC A;  3K4X A;  3GPM A;  2IX2 C;  1U7B A;  1RXM A;  3IFV A;  1RXZ A;  1AXC A;  1SXJ F;  1RWZ A;  4HK1 A;  5E0T A;  4D2G A;  1T6L A;  2HIK A;  3I2M X;  1GE8 A;  4CS5 A;  5H0T A;  3U5Z F;  1PLR A;  3V62 B;  1IZ5 A;  3GGR B;  3AIX B;  2IJX A;  3G65 B;  1YYP A;  3P87 A;  2HII B;  3FDS D;  2IZO C;  1W60 A;  2NTI B;  2ZVV A;  3A1J A;  1PLQ A;  1ISQ A;  5B7O A;  5IXA A;  4YHR A;  3U61 F;  5JNE D;  2IO4 A;  5E0V A;  5A6D A;  5IY4 A;  3AIX A;  1B77 A;  3LX2 A;  2AWA A;  3FDS C;  3U60 F;  2ZVM A;  2HII A;  5E0U A;  5CFK A;  4L6P A;  2NTI A;  4RJF A;  3AIZ A;  4L60 A;  3A1J C;  1CZD A;  3V61 B;  2Z0L A;  2HIK C;  2IZO B;  2IX2 B;  4ZTD A;  1VYJ A;  2ZVL A;  4TR6 A;  2AVT A;  1IZ4 A;  3P91 A;  3TBL A;  3GGR A;  2HII C;  3F1W A;  3G65 A;  3AIZ C; 
#chains in the Genus database with same CATH homology
 5DAI A;  3LX1 A;  5AUJ A;  1UD9 A;  1U76 A;  2IX2 A;  2OD8 A;  1B8H A;  3A1J B;  3VKX A;  3V60 B;  3GPN A;  2HIK B;  3HSL X;  3GGR C;  1UL1 A;  3HI8 A;  3P83 A;  1DML A;  3WGW A;  2IO4 B;  3G65 C;  5IWD A;  2ZVW A;  5DA7 A;  1VYM A;  2ZVK A;  2NTI C;  3A2F B;  5HAC A;  3K4X A;  3GPM A;  2IX2 C;  1U7B A;  1RXM A;  3IFV A;  1RXZ A;  1AXC A;  1SXJ F;  1RWZ A;  4HK1 A;  5E0T A;  4D2G A;  1T6L A;  2HIK A;  3I2M X;  1GE8 A;  4CS5 A;  5H0T A;  3U5Z F;  1PLR A;  3V62 B;  1IZ5 A;  3GGR B;  3AIX B;  2IJX A;  3G65 B;  1YYP A;  3P87 A;  2HII B;  3FDS D;  2IZO C;  1W60 A;  2NTI B;  2ZVV A;  3A1J A;  1PLQ A;  1ISQ A;  5B7O A;  5IXA A;  4YHR A;  3U61 F;  5JNE D;  2IO4 A;  5E0V A;  5A6D A;  5IY4 A;  3AIX A;  1B77 A;  3LX2 A;  2AWA A;  3FDS C;  3U60 F;  2ZVM A;  2HII A;  5E0U A;  5CFK A;  4L6P A;  2NTI A;  4RJF A;  3AIZ A;  4L60 A;  3A1J C;  1CZD A;  3V61 B;  2Z0L A;  2HIK C;  2IZO B;  2IX2 B;  4ZTD A;  1VYJ A;  2ZVL A;  4TR6 A;  2AVT A;  1IZ4 A;  3P91 A;  3TBL A;  3GGR A;  2HII C;  3F1W A;  3G65 A;  3AIZ C;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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