4D2GA

Crystal structure of human pcna in complex with p15 peptide
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
258
structure length
258
Chain Sequence
GPHMFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transcription
molecule keywords PROLIFERATING CELL NUCLEAR ANTIGEN
publication title Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
pubmed doi rcsb
source organism Homo sapiens
total genus 60
structure length 258
sequence length 258
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4d2gA00
4HK1A 5H0TA 2HIKC 3GPNA 3GGRC 5CFKA 5E0UA 2HIIB 3AIZC 3LX2A 3WGWA 2IZOC 3F1WA 3G65A 3P83A 2ZVKA 5B7OA 2Z0LA 3U5ZF 3A1JA 3A1JB 1YYPA 3GPMA 1U76A 3P87A 5IY4A 2IO4A 1RWZA 2NTIA 3LX1A 2IX2A 5HACA 2ZVLA 2ZVMA 4RJFA 1T6LA 3U60F 4CS5A 2HIIC 3A2FB 1PLRA 5IWDA 1CZDA 3G65B 5E0TA 3AIXA 3FDSC 2ZVVA 1UD9A 2ZVWA 3A1JC 5AUJA 2AVTA 2IO4B 1UL1A 1IZ4A 2NTIB 2IX2B 1IZ5A 3AIZA 1U7BA 1B77A 4D2GA 3P91A 5JNED 1RXZA 3U61F 4TR6A 3VKXA 1W60A 2OD8A 5E0VA 3TBLA 1GE8A 3AIXB 3G65C 1B8HA 1PLQA 3HSLX 2HIKA 3FDSD 2HIKB 1ISQA 3V61B 4ZTDA 3GGRA 3GGRB 3I2MX 3V60B 4YHRA 3V62B 1SXJF 1DMLA 2NTIC 2IX2C 2HIIA 3HI8A 1VYJA 3K4XA 1RXMA 1AXCA 2IZOB 2AWAA 5DA7A 5A6DA 5IXAA 5DAIA 3IFVA 4L6PA 2IJXA 1VYMA 4L60A
chains in the Genus database with same CATH superfamily
4HK1A 5H0TA 2HIKC 3GPNA 3GGRC 5CFKA 5E0UA 2HIIB 3AIZC 3LX2A 3WGWA 2IZOC 3F1WA 3G65A 3P83A 2ZVKA 5B7OA 2Z0LA 3U5ZF 3A1JA 3A1JB 1YYPA 3GPMA 1U76A 3P87A 5IY4A 2IO4A 1RWZA 2NTIA 3LX1A 2IX2A 5HACA 2ZVLA 2ZVMA 4RJFA 1T6LA 3U60F 4CS5A 2HIIC 3A2FB 1PLRA 5IWDA 1CZDA 3G65B 5E0TA 3AIXA 3FDSC 2ZVVA 1UD9A 2ZVWA 3A1JC 5AUJA 2AVTA 2IO4B 1UL1A 1IZ4A 2NTIB 2IX2B 1IZ5A 3AIZA 1U7BA 1B77A 4D2GA 3P91A 5JNED 1RXZA 3U61F 4TR6A 3VKXA 1W60A 2OD8A 5E0VA 3TBLA 1GE8A 3AIXB 3G65C 1B8HA 1PLQA 3HSLX 2HIKA 3FDSD 2HIKB 1ISQA 3V61B 4ZTDA 3GGRA 3GGRB 3I2MX 3V60B 4YHRA 3V62B 1SXJF 1DMLA 2NTIC 2IX2C 2HIIA 3HI8A 1VYJA 3K4XA 1RXMA 1AXCA 2IZOB 2AWAA 5DA7A 5A6DA 5IXAA 5DAIA 3IFVA 4L6PA 2IJXA 1VYMA 4L60A
chains in the Genus database with same CATH topology
4HK1A 5H0TA 2HIKC 3GPNA 3GGRC 5CFKA 5E0UA 2HIIB 3AIZC 3LX2A 3WGWA 2IZOC 3F1WA 3G65A 3P83A 2ZVKA 5B7OA 2Z0LA 3U5ZF 3A1JA 3A1JB 1YYPA 3GPMA 1U76A 3P87A 5IY4A 2IO4A 1RWZA 2NTIA 3LX1A 2IX2A 5HACA 2ZVLA 2ZVMA 4RJFA 1T6LA 3U60F 4CS5A 2HIIC 3A2FB 1PLRA 5IWDA 1CZDA 3G65B 5E0TA 3AIXA 3FDSC 2ZVVA 1UD9A 2ZVWA 3A1JC 5AUJA 2AVTA 2IO4B 1UL1A 1IZ4A 2NTIB 2IX2B 1IZ5A 3AIZA 1U7BA 1B77A 4D2GA 3P91A 5JNED 1RXZA 3U61F 4TR6A 3VKXA 1W60A 2OD8A 5E0VA 3TBLA 1GE8A 3AIXB 3G65C 1B8HA 1PLQA 3HSLX 2HIKA 3FDSD 2HIKB 1ISQA 3V61B 4ZTDA 3GGRA 3GGRB 3I2MX 3V60B 4YHRA 3V62B 1SXJF 1DMLA 2NTIC 2IX2C 2HIIA 3HI8A 1VYJA 3K4XA 1RXMA 1AXCA 2IZOB 2AWAA 5DA7A 5A6DA 5IXAA 5DAIA 3IFVA 4L6PA 2IJXA 1VYMA 4L60A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4HK1 A;  5H0T A;  2HIK C;  3GPN A;  3GGR C;  5CFK A;  5E0U A;  2HII B;  3AIZ C;  3LX2 A;  3WGW A;  2IZO C;  3F1W A;  3G65 A;  3P83 A;  2ZVK A;  5B7O A;  2Z0L A;  3U5Z F;  3A1J A;  3A1J B;  1YYP A;  3GPM A;  1U76 A;  3P87 A;  5IY4 A;  2IO4 A;  1RWZ A;  2NTI A;  3LX1 A;  2IX2 A;  5HAC A;  2ZVL A;  2ZVM A;  4RJF A;  1T6L A;  3U60 F;  4CS5 A;  2HII C;  3A2F B;  1PLR A;  5IWD A;  1CZD A;  3G65 B;  5E0T A;  3AIX A;  3FDS C;  2ZVV A;  1UD9 A;  2ZVW A;  3A1J C;  5AUJ A;  2AVT A;  2IO4 B;  1UL1 A;  1IZ4 A;  2NTI B;  2IX2 B;  1IZ5 A;  3AIZ A;  1U7B A;  1B77 A;  4D2G A;  3P91 A;  5JNE D;  1RXZ A;  3U61 F;  4TR6 A;  3VKX A;  1W60 A;  2OD8 A;  5E0V A;  3TBL A;  1GE8 A;  3AIX B;  3G65 C;  1B8H A;  1PLQ A;  3HSL X;  2HIK A;  3FDS D;  2HIK B;  1ISQ A;  3V61 B;  4ZTD A;  3GGR A;  3GGR B;  3I2M X;  3V60 B;  4YHR A;  3V62 B;  1SXJ F;  1DML A;  2NTI C;  2IX2 C;  2HII A;  3HI8 A;  1VYJ A;  3K4X A;  1RXM A;  1AXC A;  2IZO B;  2AWA A;  5DA7 A;  5A6D A;  5IXA A;  5DAI A;  3IFV A;  4L6P A;  2IJX A;  1VYM A;  4L60 A; 
#chains in the Genus database with same CATH topology
 4HK1 A;  5H0T A;  2HIK C;  3GPN A;  3GGR C;  5CFK A;  5E0U A;  2HII B;  3AIZ C;  3LX2 A;  3WGW A;  2IZO C;  3F1W A;  3G65 A;  3P83 A;  2ZVK A;  5B7O A;  2Z0L A;  3U5Z F;  3A1J A;  3A1J B;  1YYP A;  3GPM A;  1U76 A;  3P87 A;  5IY4 A;  2IO4 A;  1RWZ A;  2NTI A;  3LX1 A;  2IX2 A;  5HAC A;  2ZVL A;  2ZVM A;  4RJF A;  1T6L A;  3U60 F;  4CS5 A;  2HII C;  3A2F B;  1PLR A;  5IWD A;  1CZD A;  3G65 B;  5E0T A;  3AIX A;  3FDS C;  2ZVV A;  1UD9 A;  2ZVW A;  3A1J C;  5AUJ A;  2AVT A;  2IO4 B;  1UL1 A;  1IZ4 A;  2NTI B;  2IX2 B;  1IZ5 A;  3AIZ A;  1U7B A;  1B77 A;  4D2G A;  3P91 A;  5JNE D;  1RXZ A;  3U61 F;  4TR6 A;  3VKX A;  1W60 A;  2OD8 A;  5E0V A;  3TBL A;  1GE8 A;  3AIX B;  3G65 C;  1B8H A;  1PLQ A;  3HSL X;  2HIK A;  3FDS D;  2HIK B;  1ISQ A;  3V61 B;  4ZTD A;  3GGR A;  3GGR B;  3I2M X;  3V60 B;  4YHR A;  3V62 B;  1SXJ F;  1DML A;  2NTI C;  2IX2 C;  2HII A;  3HI8 A;  1VYJ A;  3K4X A;  1RXM A;  1AXC A;  2IZO B;  2AWA A;  5DA7 A;  5A6D A;  5IXA A;  5DAI A;  3IFV A;  4L6P A;  2IJX A;  1VYM A;  4L60 A; 
#chains in the Genus database with same CATH homology
 4HK1 A;  5H0T A;  2HIK C;  3GPN A;  3GGR C;  5CFK A;  5E0U A;  2HII B;  3AIZ C;  3LX2 A;  3WGW A;  2IZO C;  3F1W A;  3G65 A;  3P83 A;  2ZVK A;  5B7O A;  2Z0L A;  3U5Z F;  3A1J A;  3A1J B;  1YYP A;  3GPM A;  1U76 A;  3P87 A;  5IY4 A;  2IO4 A;  1RWZ A;  2NTI A;  3LX1 A;  2IX2 A;  5HAC A;  2ZVL A;  2ZVM A;  4RJF A;  1T6L A;  3U60 F;  4CS5 A;  2HII C;  3A2F B;  1PLR A;  5IWD A;  1CZD A;  3G65 B;  5E0T A;  3AIX A;  3FDS C;  2ZVV A;  1UD9 A;  2ZVW A;  3A1J C;  5AUJ A;  2AVT A;  2IO4 B;  1UL1 A;  1IZ4 A;  2NTI B;  2IX2 B;  1IZ5 A;  3AIZ A;  1U7B A;  1B77 A;  4D2G A;  3P91 A;  5JNE D;  1RXZ A;  3U61 F;  4TR6 A;  3VKX A;  1W60 A;  2OD8 A;  5E0V A;  3TBL A;  1GE8 A;  3AIX B;  3G65 C;  1B8H A;  1PLQ A;  3HSL X;  2HIK A;  3FDS D;  2HIK B;  1ISQ A;  3V61 B;  4ZTD A;  3GGR A;  3GGR B;  3I2M X;  3V60 B;  4YHR A;  3V62 B;  1SXJ F;  1DML A;  2NTI C;  2IX2 C;  2HII A;  3HI8 A;  1VYJ A;  3K4X A;  1RXM A;  1AXC A;  2IZO B;  2AWA A;  5DA7 A;  5A6D A;  5IXA A;  5DAI A;  3IFV A;  4L6P A;  2IJX A;  1VYM A;  4L60 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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