4L6PA

Structure of c22y mutant pcna protein defective in dna mismatch repair
Total Genus 61
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
255
structure length
255
Chain Sequence
HMLEAKFEEASLFKRIIDGFKDYVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Saccharomyces cerevisiae s288c
molecule keywords Proliferating cell nuclear antigen
total genus 61
structure length 255
sequence length 255
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4l6pA00
5CFKA 3IFVA 2AVTA 3P83A 3A1JC 3V60B 1T6LA 1PLRA 2ZVVA 4ZTDA 3P91A 2IX2C 1ISQA 1UL1A 2Z0LA 3U5ZF 5H0TA 2IX2A 5E0VA 1DMLA 3V62B 2IZOC 3WGWA 3GGRB 3FDSC 2IO4A 4HK1A 1B8HA 1UD9A 1SXJF 5IY4A 2ZVKA 4L6PA 3A1JA 2AWAA 5E0UA 3A2FB 3G65B 1PLQA 5HACA 5IXAA 2NTIB 5DA7A 3TBLA 1AXCA 1IZ4A 3F1WA 2OD8A 2ZVWA 3GPNA 3AIZC 3HSLX 1RWZA 4D2GA 3U61F 4TR6A 3U60F 5JNED 3AIXB 3LX1A 3P87A 2HIKB 3GPMA 2ZVMA 3AIZA 3V61B 3GGRC 3I2MX 3FDSD 2HIIB 2IX2B 1W60A 5B7OA 4YHRA 1VYJA 2HIKC 1VYMA 3LX2A 5AUJA 3GGRA 1YYPA 1IZ5A 2IO4B 5DAIA 2ZVLA 1CZDA 2HIIC 1RXZA 3HI8A 3G65C 1B77A 4CS5A 3VKXA 2NTIC 3AIXA 2HIKA 3A1JB 2IZOB 1RXMA 1U7BA 1U76A 5E0TA 1GE8A 4RJFA 5A6DA 2HIIA 3G65A 5IWDA 2IJXA 3K4XA 4L60A 2NTIA
chains in the Genus database with same CATH superfamily
5CFKA 3IFVA 2AVTA 3P83A 3A1JC 3V60B 1T6LA 1PLRA 2ZVVA 4ZTDA 3P91A 2IX2C 1ISQA 1UL1A 2Z0LA 3U5ZF 5H0TA 2IX2A 5E0VA 1DMLA 3V62B 2IZOC 3WGWA 3GGRB 3FDSC 2IO4A 4HK1A 1B8HA 1UD9A 1SXJF 5IY4A 2ZVKA 4L6PA 3A1JA 2AWAA 5E0UA 3A2FB 3G65B 1PLQA 5HACA 5IXAA 2NTIB 5DA7A 3TBLA 1AXCA 1IZ4A 3F1WA 2OD8A 2ZVWA 3GPNA 3AIZC 3HSLX 1RWZA 4D2GA 3U61F 4TR6A 3U60F 5JNED 3AIXB 3LX1A 3P87A 2HIKB 3GPMA 2ZVMA 3AIZA 3V61B 3GGRC 3I2MX 3FDSD 2HIIB 2IX2B 1W60A 5B7OA 4YHRA 1VYJA 2HIKC 1VYMA 3LX2A 5AUJA 3GGRA 1YYPA 1IZ5A 2IO4B 5DAIA 2ZVLA 1CZDA 2HIIC 1RXZA 3HI8A 3G65C 1B77A 4CS5A 3VKXA 2NTIC 3AIXA 2HIKA 3A1JB 2IZOB 1RXMA 1U7BA 1U76A 5E0TA 1GE8A 4RJFA 5A6DA 2HIIA 3G65A 5IWDA 2IJXA 3K4XA 4L60A 2NTIA
chains in the Genus database with same CATH topology
5CFKA 3IFVA 2AVTA 3P83A 3A1JC 3V60B 1T6LA 1PLRA 2ZVVA 4ZTDA 3P91A 2IX2C 1ISQA 1UL1A 2Z0LA 3U5ZF 5H0TA 2IX2A 5E0VA 1DMLA 3V62B 2IZOC 3WGWA 3GGRB 3FDSC 2IO4A 4HK1A 1B8HA 1UD9A 1SXJF 5IY4A 2ZVKA 4L6PA 3A1JA 2AWAA 5E0UA 3A2FB 3G65B 1PLQA 5HACA 5IXAA 2NTIB 5DA7A 3TBLA 1AXCA 1IZ4A 3F1WA 2OD8A 2ZVWA 3GPNA 3AIZC 3HSLX 1RWZA 4D2GA 3U61F 4TR6A 3U60F 5JNED 3AIXB 3LX1A 3P87A 2HIKB 3GPMA 2ZVMA 3AIZA 3V61B 3GGRC 3I2MX 3FDSD 2HIIB 2IX2B 1W60A 5B7OA 4YHRA 1VYJA 2HIKC 1VYMA 3LX2A 5AUJA 3GGRA 1YYPA 1IZ5A 2IO4B 5DAIA 2ZVLA 1CZDA 2HIIC 1RXZA 3HI8A 3G65C 1B77A 4CS5A 3VKXA 2NTIC 3AIXA 2HIKA 3A1JB 2IZOB 1RXMA 1U7BA 1U76A 5E0TA 1GE8A 4RJFA 5A6DA 2HIIA 3G65A 5IWDA 2IJXA 3K4XA 4L60A 2NTIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CFK A;  3IFV A;  2AVT A;  3P83 A;  3A1J C;  3V60 B;  1T6L A;  1PLR A;  2ZVV A;  4ZTD A;  3P91 A;  2IX2 C;  1ISQ A;  1UL1 A;  2Z0L A;  3U5Z F;  5H0T A;  2IX2 A;  5E0V A;  1DML A;  3V62 B;  2IZO C;  3WGW A;  3GGR B;  3FDS C;  2IO4 A;  4HK1 A;  1B8H A;  1UD9 A;  1SXJ F;  5IY4 A;  2ZVK A;  4L6P A;  3A1J A;  2AWA A;  5E0U A;  3A2F B;  3G65 B;  1PLQ A;  5HAC A;  5IXA A;  2NTI B;  5DA7 A;  3TBL A;  1AXC A;  1IZ4 A;  3F1W A;  2OD8 A;  2ZVW A;  3GPN A;  3AIZ C;  3HSL X;  1RWZ A;  4D2G A;  3U61 F;  4TR6 A;  3U60 F;  5JNE D;  3AIX B;  3LX1 A;  3P87 A;  2HIK B;  3GPM A;  2ZVM A;  3AIZ A;  3V61 B;  3GGR C;  3I2M X;  3FDS D;  2HII B;  2IX2 B;  1W60 A;  5B7O A;  4YHR A;  1VYJ A;  2HIK C;  1VYM A;  3LX2 A;  5AUJ A;  3GGR A;  1YYP A;  1IZ5 A;  2IO4 B;  5DAI A;  2ZVL A;  1CZD A;  2HII C;  1RXZ A;  3HI8 A;  3G65 C;  1B77 A;  4CS5 A;  3VKX A;  2NTI C;  3AIX A;  2HIK A;  3A1J B;  2IZO B;  1RXM A;  1U7B A;  1U76 A;  5E0T A;  1GE8 A;  4RJF A;  5A6D A;  2HII A;  3G65 A;  5IWD A;  2IJX A;  3K4X A;  4L60 A;  2NTI A; 
#chains in the Genus database with same CATH topology
 5CFK A;  3IFV A;  2AVT A;  3P83 A;  3A1J C;  3V60 B;  1T6L A;  1PLR A;  2ZVV A;  4ZTD A;  3P91 A;  2IX2 C;  1ISQ A;  1UL1 A;  2Z0L A;  3U5Z F;  5H0T A;  2IX2 A;  5E0V A;  1DML A;  3V62 B;  2IZO C;  3WGW A;  3GGR B;  3FDS C;  2IO4 A;  4HK1 A;  1B8H A;  1UD9 A;  1SXJ F;  5IY4 A;  2ZVK A;  4L6P A;  3A1J A;  2AWA A;  5E0U A;  3A2F B;  3G65 B;  1PLQ A;  5HAC A;  5IXA A;  2NTI B;  5DA7 A;  3TBL A;  1AXC A;  1IZ4 A;  3F1W A;  2OD8 A;  2ZVW A;  3GPN A;  3AIZ C;  3HSL X;  1RWZ A;  4D2G A;  3U61 F;  4TR6 A;  3U60 F;  5JNE D;  3AIX B;  3LX1 A;  3P87 A;  2HIK B;  3GPM A;  2ZVM A;  3AIZ A;  3V61 B;  3GGR C;  3I2M X;  3FDS D;  2HII B;  2IX2 B;  1W60 A;  5B7O A;  4YHR A;  1VYJ A;  2HIK C;  1VYM A;  3LX2 A;  5AUJ A;  3GGR A;  1YYP A;  1IZ5 A;  2IO4 B;  5DAI A;  2ZVL A;  1CZD A;  2HII C;  1RXZ A;  3HI8 A;  3G65 C;  1B77 A;  4CS5 A;  3VKX A;  2NTI C;  3AIX A;  2HIK A;  3A1J B;  2IZO B;  1RXM A;  1U7B A;  1U76 A;  5E0T A;  1GE8 A;  4RJF A;  5A6D A;  2HII A;  3G65 A;  5IWD A;  2IJX A;  3K4X A;  4L60 A;  2NTI A; 
#chains in the Genus database with same CATH homology
 5CFK A;  3IFV A;  2AVT A;  3P83 A;  3A1J C;  3V60 B;  1T6L A;  1PLR A;  2ZVV A;  4ZTD A;  3P91 A;  2IX2 C;  1ISQ A;  1UL1 A;  2Z0L A;  3U5Z F;  5H0T A;  2IX2 A;  5E0V A;  1DML A;  3V62 B;  2IZO C;  3WGW A;  3GGR B;  3FDS C;  2IO4 A;  4HK1 A;  1B8H A;  1UD9 A;  1SXJ F;  5IY4 A;  2ZVK A;  4L6P A;  3A1J A;  2AWA A;  5E0U A;  3A2F B;  3G65 B;  1PLQ A;  5HAC A;  5IXA A;  2NTI B;  5DA7 A;  3TBL A;  1AXC A;  1IZ4 A;  3F1W A;  2OD8 A;  2ZVW A;  3GPN A;  3AIZ C;  3HSL X;  1RWZ A;  4D2G A;  3U61 F;  4TR6 A;  3U60 F;  5JNE D;  3AIX B;  3LX1 A;  3P87 A;  2HIK B;  3GPM A;  2ZVM A;  3AIZ A;  3V61 B;  3GGR C;  3I2M X;  3FDS D;  2HII B;  2IX2 B;  1W60 A;  5B7O A;  4YHR A;  1VYJ A;  2HIK C;  1VYM A;  3LX2 A;  5AUJ A;  3GGR A;  1YYP A;  1IZ5 A;  2IO4 B;  5DAI A;  2ZVL A;  1CZD A;  2HII C;  1RXZ A;  3HI8 A;  3G65 C;  1B77 A;  4CS5 A;  3VKX A;  2NTI C;  3AIX A;  2HIK A;  3A1J B;  2IZO B;  1RXM A;  1U7B A;  1U76 A;  5E0T A;  1GE8 A;  4RJF A;  5A6D A;  2HII A;  3G65 A;  5IWD A;  2IJX A;  3K4X A;  4L60 A;  2NTI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...