4NGBA

Structure of human dicer platform-paz-connector helix cassette in complex with 12-mer sirna having uu-3' ends (2.25 angstrom resolution)
Total Genus 70
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
298
structure length
276
Chain Sequence
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKPALAYCVLPLNVVSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 70
structure length 276
sequence length 298
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4ngbA02
5JS2A 1T2RA 2L5CA 4OLBA 1R6ZA 4W5NA 4NGFA 1T2SA 4NGCA 4NHAA 4Z4GA 3O7VX 5T7BA 2XFMA 4Z4HA 3MJ0A 4Z4CA 4NH5A 4NH6A 4Z4IA 1SI2A 4OLAA 4Z4FA 4NGGA 3QIRA 4W5QA 4NGBA 4NGDA 4KREA 5JS1A 4W5TA 4NH3A 3O3IX 1VYNA 2L5DA 4W5RA 2FFLA 4KRFA 4F3TA 2QVWA 5KI6A 4Z4EA 4W5OA 1SI3A 3O7XA 3O6EX 1R4KA
chains in the Genus database with same CATH superfamily
5JS2A 1T2RA 2L5CA 4OLBA 1R6ZA 3DLHA 4W5NA 4NGFA 1T2SA 3U1UA 4NHAA 4Z4GA 3O7VX 5T7BA 4NGCA 2XFMA 4Z4HA 3F73A 3HO1A 3MJ0A 4Z4CA 4NH5A 4NH6A 1U04A 4L1PA 1Z26A 3HK2A 4L1UA 4Z4IA 1SI2A 4OLAA 4Z4FA 2DB9A 3QIRA 3HJFA 4NGGA 4W5QA 4NGBA 4NGDA 4KREA 3DA5A 3HVRA 5JS1A 4W5TA 4NH3A 3O3IX 2BZEA 1VYNA 2L5DA 4W5RA 2FFLA 4KRFA 4F3TA 2QVWA 5KI6A 4Z4EA 3DLBA 4W5OA 1Z25A 1SI3A 3O7XA 3O6EX 3HM9A 1R4KA
chains in the Genus database with same CATH topology
5JS2A 1T2RA 2L5CA 4OLBA 1R6ZA 3DLHA 4W5NA 4NGFA 1T2SA 3U1UA 4NHAA 4Z4GA 3O7VX 5T7BA 4NGCA 2XFMA 4Z4HA 3F73A 3HO1A 3MJ0A 4Z4CA 4NH5A 4NH6A 1U04A 4L1PA 1Z26A 3HK2A 4L1UA 4Z4IA 1SI2A 4OLAA 4Z4FA 2DB9A 3QIRA 3HJFA 4NGGA 4W5QA 4NGBA 4NGDA 4KREA 3DA5A 3HVRA 5JS1A 4W5TA 4NH3A 3O3IX 2BZEA 1VYNA 2L5DA 4W5RA 2FFLA 4KRFA 4F3TA 2QVWA 5KI6A 4Z4EA 3DLBA 4W5OA 1Z25A 1SI3A 3O7XA 3O6EX 3HM9A 1R4KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JS2 A;  1T2R A;  2L5C A;  4OLB A;  1R6Z A;  4W5N A;  4NGF A;  1T2S A;  4NGC A;  4NHA A;  4Z4G A;  3O7V X;  5T7B A;  2XFM A;  4Z4H A;  3MJ0 A;  4Z4C A;  4NH5 A;  4NH6 A;  4Z4I A;  1SI2 A;  4OLA A;  4Z4F A;  4NGG A;  3QIR A;  4W5Q A;  4NGB A;  4NGD A;  4KRE A;  5JS1 A;  4W5T A;  4NH3 A;  3O3I X;  1VYN A;  2L5D A;  4W5R A;  2FFL A;  4KRF A;  4F3T A;  2QVW A;  5KI6 A;  4Z4E A;  4W5O A;  1SI3 A;  3O7X A;  3O6E X;  1R4K A; 
#chains in the Genus database with same CATH topology
 5JS2 A;  1T2R A;  2L5C A;  4OLB A;  1R6Z A;  3DLH A;  4W5N A;  4NGF A;  1T2S A;  3U1U A;  4NHA A;  4Z4G A;  3O7V X;  5T7B A;  4NGC A;  2XFM A;  4Z4H A;  3F73 A;  3HO1 A;  3MJ0 A;  4Z4C A;  4NH5 A;  4NH6 A;  1U04 A;  4L1P A;  1Z26 A;  3HK2 A;  4L1U A;  4Z4I A;  1SI2 A;  4OLA A;  4Z4F A;  2DB9 A;  3QIR A;  3HJF A;  4NGG A;  4W5Q A;  4NGB A;  4NGD A;  4KRE A;  3DA5 A;  3HVR A;  5JS1 A;  4W5T A;  4NH3 A;  3O3I X;  2BZE A;  1VYN A;  2L5D A;  4W5R A;  2FFL A;  4KRF A;  4F3T A;  2QVW A;  5KI6 A;  4Z4E A;  3DLB A;  4W5O A;  1Z25 A;  1SI3 A;  3O7X A;  3O6E X;  3HM9 A;  1R4K A; 
#chains in the Genus database with same CATH homology
 5JS2 A;  1T2R A;  2L5C A;  4OLB A;  1R6Z A;  3DLH A;  4W5N A;  4NGF A;  1T2S A;  3U1U A;  4NHA A;  4Z4G A;  3O7V X;  5T7B A;  4NGC A;  2XFM A;  4Z4H A;  3F73 A;  3HO1 A;  3MJ0 A;  4Z4C A;  4NH5 A;  4NH6 A;  1U04 A;  4L1P A;  1Z26 A;  3HK2 A;  4L1U A;  4Z4I A;  1SI2 A;  4OLA A;  4Z4F A;  2DB9 A;  3QIR A;  3HJF A;  4NGG A;  4W5Q A;  4NGB A;  4NGD A;  4KRE A;  3DA5 A;  3HVR A;  5JS1 A;  4W5T A;  4NH3 A;  3O3I X;  2BZE A;  1VYN A;  2L5D A;  4W5R A;  2FFL A;  4KRF A;  4F3T A;  2QVW A;  5KI6 A;  4Z4E A;  3DLB A;  4W5O A;  1Z25 A;  1SI3 A;  3O7X A;  3O6E X;  3HM9 A;  1R4K A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...