4NH3A

Structure of human dicer platform-paz-connector helix cassette in complex with 13-mer sirna having 5'-pu and uu-3' ends (2.6 angstrom resolution)
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
298
structure length
268
Chain Sequence
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLYCVLPLNVVTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 62
structure length 268
sequence length 298
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4nh3A02
1T2RA 4F3TA 4Z4CA 4Z4EA 5JS1A 2FFLA 4W5QA 4Z4IA 1SI3A 4W5TA 4NGGA 4NGFA 1VYNA 4OLBA 4W5OA 1SI2A 4Z4GA 4OLAA 1R6ZA 3O6EX 4NGCA 4W5NA 3O7VX 5T7BA 4Z4FA 4W5RA 4NGDA 3O3IX 2QVWA 4KRFA 2L5CA 4NGBA 1R4KA 4NH6A 4NH5A 5JS2A 4Z4HA 2XFMA 3MJ0A 5KI6A 4NH3A 1T2SA 4NHAA 3QIRA 4KREA 3O7XA 2L5DA
chains in the Genus database with same CATH superfamily
1T2RA 4F3TA 4Z4CA 3DLBA 4Z4EA 5JS1A 2FFLA 4W5QA 4Z4IA 3F73A 1SI3A 3HJFA 1Z26A 4W5TA 3HM9A 4NGGA 1Z25A 4NGFA 1VYNA 3U1UA 4W5OA 4OLBA 1SI2A 4Z4GA 4OLAA 1R6ZA 4L1UA 3HK2A 3O6EX 2BZEA 3DLHA 4NGCA 4W5NA 3O7VX 5T7BA 4Z4FA 4W5RA 4NGDA 3O3IX 2QVWA 4KRFA 2DB9A 2L5CA 1R4KA 4NGBA 4NH6A 4NH5A 5JS2A 1U04A 4Z4HA 2XFMA 3HVRA 3DA5A 3MJ0A 5KI6A 4NH3A 1T2SA 4NHAA 3HO1A 3QIRA 4KREA 3O7XA 2L5DA 4L1PA
chains in the Genus database with same CATH topology
1T2RA 4F3TA 4Z4CA 3DLBA 4Z4EA 5JS1A 2FFLA 4W5QA 4Z4IA 3F73A 1SI3A 3HJFA 1Z26A 4W5TA 3HM9A 4NGGA 1Z25A 4NGFA 1VYNA 3U1UA 4W5OA 4OLBA 1SI2A 4Z4GA 4OLAA 1R6ZA 4L1UA 3HK2A 3O6EX 2BZEA 3DLHA 4NGCA 4W5NA 3O7VX 5T7BA 4Z4FA 4W5RA 4NGDA 3O3IX 2QVWA 4KRFA 2DB9A 2L5CA 1R4KA 4NGBA 4NH6A 4NH5A 5JS2A 1U04A 4Z4HA 2XFMA 3HVRA 3DA5A 3MJ0A 5KI6A 4NH3A 1T2SA 4NHAA 3HO1A 3QIRA 4KREA 3O7XA 2L5DA 4L1PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T2R A;  4F3T A;  4Z4C A;  4Z4E A;  5JS1 A;  2FFL A;  4W5Q A;  4Z4I A;  1SI3 A;  4W5T A;  4NGG A;  4NGF A;  1VYN A;  4OLB A;  4W5O A;  1SI2 A;  4Z4G A;  4OLA A;  1R6Z A;  3O6E X;  4NGC A;  4W5N A;  3O7V X;  5T7B A;  4Z4F A;  4W5R A;  4NGD A;  3O3I X;  2QVW A;  4KRF A;  2L5C A;  4NGB A;  1R4K A;  4NH6 A;  4NH5 A;  5JS2 A;  4Z4H A;  2XFM A;  3MJ0 A;  5KI6 A;  4NH3 A;  1T2S A;  4NHA A;  3QIR A;  4KRE A;  3O7X A;  2L5D A; 
#chains in the Genus database with same CATH topology
 1T2R A;  4F3T A;  4Z4C A;  3DLB A;  4Z4E A;  5JS1 A;  2FFL A;  4W5Q A;  4Z4I A;  3F73 A;  1SI3 A;  3HJF A;  1Z26 A;  4W5T A;  3HM9 A;  4NGG A;  1Z25 A;  4NGF A;  1VYN A;  3U1U A;  4W5O A;  4OLB A;  1SI2 A;  4Z4G A;  4OLA A;  1R6Z A;  4L1U A;  3HK2 A;  3O6E X;  2BZE A;  3DLH A;  4NGC A;  4W5N A;  3O7V X;  5T7B A;  4Z4F A;  4W5R A;  4NGD A;  3O3I X;  2QVW A;  4KRF A;  2DB9 A;  2L5C A;  1R4K A;  4NGB A;  4NH6 A;  4NH5 A;  5JS2 A;  1U04 A;  4Z4H A;  2XFM A;  3HVR A;  3DA5 A;  3MJ0 A;  5KI6 A;  4NH3 A;  1T2S A;  4NHA A;  3HO1 A;  3QIR A;  4KRE A;  3O7X A;  2L5D A;  4L1P A; 
#chains in the Genus database with same CATH homology
 1T2R A;  4F3T A;  4Z4C A;  3DLB A;  4Z4E A;  5JS1 A;  2FFL A;  4W5Q A;  4Z4I A;  3F73 A;  1SI3 A;  3HJF A;  1Z26 A;  4W5T A;  3HM9 A;  4NGG A;  1Z25 A;  4NGF A;  1VYN A;  3U1U A;  4W5O A;  4OLB A;  1SI2 A;  4Z4G A;  4OLA A;  1R6Z A;  4L1U A;  3HK2 A;  3O6E X;  2BZE A;  3DLH A;  4NGC A;  4W5N A;  3O7V X;  5T7B A;  4Z4F A;  4W5R A;  4NGD A;  3O3I X;  2QVW A;  4KRF A;  2DB9 A;  2L5C A;  1R4K A;  4NGB A;  4NH6 A;  4NH5 A;  5JS2 A;  1U04 A;  4Z4H A;  2XFM A;  3HVR A;  3DA5 A;  3MJ0 A;  5KI6 A;  4NH3 A;  1T2S A;  4NHA A;  3HO1 A;  3QIR A;  4KRE A;  3O7X A;  2L5D A;  4L1P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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