4NH5A

Structure of human dicer platform-paz-connector helix cassette in complex with 14-mer sirna having 5'-puu and uu-3' ends (2.55 angstrom resolution)
Total Genus 67
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
298
structure length
271
Chain Sequence
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKYCVLPLNVVNSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 67
structure length 271
sequence length 298
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4nh5A02
1VYNA 1T2RA 4NGCA 2FFLA 2L5CA 1T2SA 4OLAA 4KRFA 3QIRA 4Z4IA 2QVWA 4W5TA 4W5QA 4OLBA 4NH3A 4NHAA 4W5RA 4Z4EA 4NGDA 4Z4GA 2XFMA 5JS2A 4Z4FA 5JS1A 4W5OA 4KREA 4NGFA 5T7BA 2L5DA 1SI2A 3O7VX 3O7XA 5KI6A 4Z4CA 4NH6A 3MJ0A 3O3IX 4F3TA 3O6EX 4Z4HA 1SI3A 4NH5A 4NGGA 1R6ZA 1R4KA 4W5NA 4NGBA
chains in the Genus database with same CATH superfamily
1VYNA 1T2RA 4NGCA 3DA5A 4W5NA 2FFLA 2L5CA 1T2SA 4OLAA 2DB9A 4L1UA 4KRFA 3QIRA 4L1PA 4Z4IA 1U04A 2QVWA 4W5TA 4W5QA 3HK2A 4OLBA 4NH3A 4NHAA 4W5RA 4Z4EA 4NGDA 3DLBA 5JS2A 2XFMA 4Z4GA 4Z4FA 5JS1A 4W5OA 4KREA 2BZEA 4NGFA 5T7BA 2L5DA 3F73A 1SI2A 3U1UA 3HJFA 3O7VX 3O7XA 5KI6A 1Z25A 4Z4CA 4NH6A 3MJ0A 3O3IX 4F3TA 3HVRA 3O6EX 1Z26A 4Z4HA 1SI3A 4NH5A 4NGGA 1R6ZA 1R4KA 3DLHA 3HM9A 4NGBA 3HO1A
chains in the Genus database with same CATH topology
1VYNA 1T2RA 4NGCA 3DA5A 4W5NA 2FFLA 2L5CA 1T2SA 4OLAA 2DB9A 4L1UA 4KRFA 3QIRA 4L1PA 4Z4IA 1U04A 2QVWA 4W5TA 4W5QA 3HK2A 4OLBA 4NH3A 4NHAA 4W5RA 4Z4EA 4NGDA 3DLBA 5JS2A 2XFMA 4Z4GA 4Z4FA 5JS1A 4W5OA 4KREA 2BZEA 4NGFA 5T7BA 2L5DA 3F73A 1SI2A 3U1UA 3HJFA 3O7VX 3O7XA 5KI6A 1Z25A 4Z4CA 4NH6A 3MJ0A 3O3IX 4F3TA 3HVRA 3O6EX 1Z26A 4Z4HA 1SI3A 4NH5A 4NGGA 1R6ZA 1R4KA 3DLHA 3HM9A 4NGBA 3HO1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VYN A;  1T2R A;  4NGC A;  2FFL A;  2L5C A;  1T2S A;  4OLA A;  4KRF A;  3QIR A;  4Z4I A;  2QVW A;  4W5T A;  4W5Q A;  4OLB A;  4NH3 A;  4NHA A;  4W5R A;  4Z4E A;  4NGD A;  4Z4G A;  2XFM A;  5JS2 A;  4Z4F A;  5JS1 A;  4W5O A;  4KRE A;  4NGF A;  5T7B A;  2L5D A;  1SI2 A;  3O7V X;  3O7X A;  5KI6 A;  4Z4C A;  4NH6 A;  3MJ0 A;  3O3I X;  4F3T A;  3O6E X;  4Z4H A;  1SI3 A;  4NH5 A;  4NGG A;  1R6Z A;  1R4K A;  4W5N A;  4NGB A; 
#chains in the Genus database with same CATH topology
 1VYN A;  1T2R A;  4NGC A;  3DA5 A;  4W5N A;  2FFL A;  2L5C A;  1T2S A;  4OLA A;  2DB9 A;  4L1U A;  4KRF A;  3QIR A;  4L1P A;  4Z4I A;  1U04 A;  2QVW A;  4W5T A;  4W5Q A;  3HK2 A;  4OLB A;  4NH3 A;  4NHA A;  4W5R A;  4Z4E A;  4NGD A;  3DLB A;  5JS2 A;  2XFM A;  4Z4G A;  4Z4F A;  5JS1 A;  4W5O A;  4KRE A;  2BZE A;  4NGF A;  5T7B A;  2L5D A;  3F73 A;  1SI2 A;  3U1U A;  3HJF A;  3O7V X;  3O7X A;  5KI6 A;  1Z25 A;  4Z4C A;  4NH6 A;  3MJ0 A;  3O3I X;  4F3T A;  3HVR A;  3O6E X;  1Z26 A;  4Z4H A;  1SI3 A;  4NH5 A;  4NGG A;  1R6Z A;  1R4K A;  3DLH A;  3HM9 A;  4NGB A;  3HO1 A; 
#chains in the Genus database with same CATH homology
 1VYN A;  1T2R A;  4NGC A;  3DA5 A;  4W5N A;  2FFL A;  2L5C A;  1T2S A;  4OLA A;  2DB9 A;  4L1U A;  4KRF A;  3QIR A;  4L1P A;  4Z4I A;  1U04 A;  2QVW A;  4W5T A;  4W5Q A;  3HK2 A;  4OLB A;  4NH3 A;  4NHA A;  4W5R A;  4Z4E A;  4NGD A;  3DLB A;  5JS2 A;  2XFM A;  4Z4G A;  4Z4F A;  5JS1 A;  4W5O A;  4KRE A;  2BZE A;  4NGF A;  5T7B A;  2L5D A;  3F73 A;  1SI2 A;  3U1U A;  3HJF A;  3O7V X;  3O7X A;  5KI6 A;  1Z25 A;  4Z4C A;  4NH6 A;  3MJ0 A;  3O3I X;  4F3T A;  3HVR A;  3O6E X;  1Z26 A;  4Z4H A;  1SI3 A;  4NH5 A;  4NGG A;  1R6Z A;  1R4K A;  3DLH A;  3HM9 A;  4NGB A;  3HO1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...