4NH6A

Structure of human dicer platform-paz-connector helix cassette in complex with 15-mer sirna having 5'-puuu and uu-3' ends (2.55 angstrom resolution)
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
299
structure length
272
Chain Sequence
DQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEAYCVLPLNVVTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 68
structure length 272
sequence length 299
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4nh6A02
5T7BA 2FFLA 4Z4CA 4Z4FA 3O3IX 4F3TA 4KRFA 1SI3A 4Z4EA 4Z4IA 3QIRA 5JS2A 4W5TA 4OLBA 4NGCA 3O6EX 4NH6A 5KI6A 4OLAA 2XFMA 4KREA 4NGDA 4Z4HA 4NHAA 4NGBA 3MJ0A 1T2RA 1VYNA 2L5DA 4NH5A 4NGFA 1SI2A 4W5QA 4Z4GA 4W5NA 4NGGA 2QVWA 4W5RA 3O7VX 1R6ZA 5JS1A 1T2SA 2L5CA 4NH3A 3O7XA 4W5OA 1R4KA
chains in the Genus database with same CATH superfamily
5T7BA 2FFLA 4Z4CA 4Z4FA 3O3IX 4F3TA 3HM9A 4KRFA 1SI3A 4Z4EA 4Z4IA 3HJFA 3F73A 3QIRA 5JS2A 4W5TA 4OLBA 1Z25A 4NGCA 3O6EX 4NH6A 4L1PA 3HK2A 1Z26A 5KI6A 4OLAA 2XFMA 3DA5A 4L1UA 4NGDA 4KREA 4Z4HA 4NHAA 4NGBA 3MJ0A 1U04A 1T2RA 1VYNA 2BZEA 2L5DA 4NH5A 4NGFA 1SI2A 4W5QA 4Z4GA 3U1UA 4NGGA 4W5NA 2QVWA 4W5RA 3O7VX 1R6ZA 3DLBA 3HVRA 5JS1A 1T2SA 2DB9A 2L5CA 4NH3A 3O7XA 3DLHA 4W5OA 3HO1A 1R4KA
chains in the Genus database with same CATH topology
5T7BA 2FFLA 4Z4CA 4Z4FA 3O3IX 4F3TA 3HM9A 4KRFA 1SI3A 4Z4EA 4Z4IA 3HJFA 3F73A 3QIRA 5JS2A 4W5TA 4OLBA 1Z25A 4NGCA 3O6EX 4NH6A 4L1PA 3HK2A 1Z26A 5KI6A 4OLAA 2XFMA 3DA5A 4L1UA 4NGDA 4KREA 4Z4HA 4NHAA 4NGBA 3MJ0A 1U04A 1T2RA 1VYNA 2BZEA 2L5DA 4NH5A 4NGFA 1SI2A 4W5QA 4Z4GA 3U1UA 4NGGA 4W5NA 2QVWA 4W5RA 3O7VX 1R6ZA 3DLBA 3HVRA 5JS1A 1T2SA 2DB9A 2L5CA 4NH3A 3O7XA 3DLHA 4W5OA 3HO1A 1R4KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5T7B A;  2FFL A;  4Z4C A;  4Z4F A;  3O3I X;  4F3T A;  4KRF A;  1SI3 A;  4Z4E A;  4Z4I A;  3QIR A;  5JS2 A;  4W5T A;  4OLB A;  4NGC A;  3O6E X;  4NH6 A;  5KI6 A;  4OLA A;  2XFM A;  4KRE A;  4NGD A;  4Z4H A;  4NHA A;  4NGB A;  3MJ0 A;  1T2R A;  1VYN A;  2L5D A;  4NH5 A;  4NGF A;  1SI2 A;  4W5Q A;  4Z4G A;  4W5N A;  4NGG A;  2QVW A;  4W5R A;  3O7V X;  1R6Z A;  5JS1 A;  1T2S A;  2L5C A;  4NH3 A;  3O7X A;  4W5O A;  1R4K A; 
#chains in the Genus database with same CATH topology
 5T7B A;  2FFL A;  4Z4C A;  4Z4F A;  3O3I X;  4F3T A;  3HM9 A;  4KRF A;  1SI3 A;  4Z4E A;  4Z4I A;  3HJF A;  3F73 A;  3QIR A;  5JS2 A;  4W5T A;  4OLB A;  1Z25 A;  4NGC A;  3O6E X;  4NH6 A;  4L1P A;  3HK2 A;  1Z26 A;  5KI6 A;  4OLA A;  2XFM A;  3DA5 A;  4L1U A;  4NGD A;  4KRE A;  4Z4H A;  4NHA A;  4NGB A;  3MJ0 A;  1U04 A;  1T2R A;  1VYN A;  2BZE A;  2L5D A;  4NH5 A;  4NGF A;  1SI2 A;  4W5Q A;  4Z4G A;  3U1U A;  4NGG A;  4W5N A;  2QVW A;  4W5R A;  3O7V X;  1R6Z A;  3DLB A;  3HVR A;  5JS1 A;  1T2S A;  2DB9 A;  2L5C A;  4NH3 A;  3O7X A;  3DLH A;  4W5O A;  3HO1 A;  1R4K A; 
#chains in the Genus database with same CATH homology
 5T7B A;  2FFL A;  4Z4C A;  4Z4F A;  3O3I X;  4F3T A;  3HM9 A;  4KRF A;  1SI3 A;  4Z4E A;  4Z4I A;  3HJF A;  3F73 A;  3QIR A;  5JS2 A;  4W5T A;  4OLB A;  1Z25 A;  4NGC A;  3O6E X;  4NH6 A;  4L1P A;  3HK2 A;  1Z26 A;  5KI6 A;  4OLA A;  2XFM A;  3DA5 A;  4L1U A;  4NGD A;  4KRE A;  4Z4H A;  4NHA A;  4NGB A;  3MJ0 A;  1U04 A;  1T2R A;  1VYN A;  2BZE A;  2L5D A;  4NH5 A;  4NGF A;  1SI2 A;  4W5Q A;  4Z4G A;  3U1U A;  4NGG A;  4W5N A;  2QVW A;  4W5R A;  3O7V X;  1R6Z A;  3DLB A;  3HVR A;  5JS1 A;  1T2S A;  2DB9 A;  2L5C A;  4NH3 A;  3O7X A;  3DLH A;  4W5O A;  3HO1 A;  1R4K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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