4RJFA

Crystal structure of the human sliding clamp at 2.0 angstrom resolution
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
255
structure length
255
Chain Sequence
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
pubmed doi rcsb
molecule tags Replication
source organism Homo sapiens
molecule keywords Proliferating cell nuclear antigen
total genus 53
structure length 255
sequence length 255
chains with identical sequence C, E
ec nomenclature
pdb deposition date 2014-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 4rjfA00
4CS5A 2HIIA 2HIKC 3V60B 3K4XA 1RWZA 1T6LA 1PLQA 3HI8A 5E0VA 5IXAA 3U61F 2Z0LA 5HACA 5DAIA 3A1JB 1U7BA 5DA7A 4L60A 3WGWA 3A1JC 1ISQA 5B7OA 3AIXB 5H0TA 3I2MX 3GPMA 3F1WA 1SXJF 2HIIB 3IFVA 3LX2A 3P91A 1PLRA 2AVTA 3A2FB 1B77A 3G65C 2HIIC 1UL1A 4TR6A 2NTIA 4ZTDA 3U60F 1W60A 5CFKA 3V62B 5IY4A 5A6DA 5IWDA 4YHRA 3GGRA 2IO4A 3HSLX 1AXCA 5AUJA 2ZVKA 1IZ4A 1RXMA 3G65B 1YYPA 3FDSD 4HK1A 1DMLA 3TBLA 2IX2A 3AIZA 2AWAA 4L6PA 2ZVMA 2HIKA 1GE8A 2IZOB 3AIXA 2OD8A 5E0TA 1CZDA 3P87A 2ZVLA 3P83A 2NTIC 2IZOC 5E0UA 1RXZA 1B8HA 3GGRB 3LX1A 2IO4B 4D2GA 3A1JA 3U5ZF 3GGRC 3FDSC 2ZVWA 3GPNA 3V61B 5JNED 3VKXA 1UD9A 2IX2B 2IJXA 4RJFA 2NTIB 2HIKB 2ZVVA 1VYMA 1U76A 1IZ5A 2IX2C 1VYJA 3AIZC 3G65A
chains in the Genus database with same CATH superfamily
4CS5A 2HIIA 2HIKC 3V60B 3K4XA 1RWZA 1T6LA 1PLQA 3HI8A 5E0VA 5IXAA 3U61F 2Z0LA 5HACA 5DAIA 3A1JB 1U7BA 5DA7A 4L60A 3WGWA 3A1JC 1ISQA 5B7OA 3AIXB 5H0TA 3I2MX 3GPMA 3F1WA 1SXJF 2HIIB 3IFVA 3LX2A 3P91A 1PLRA 2AVTA 3A2FB 1B77A 3G65C 2HIIC 1UL1A 4TR6A 2NTIA 4ZTDA 3U60F 1W60A 5CFKA 3V62B 5IY4A 5A6DA 5IWDA 4YHRA 3GGRA 2IO4A 3HSLX 1AXCA 5AUJA 2ZVKA 1IZ4A 1RXMA 3G65B 1YYPA 3FDSD 4HK1A 1DMLA 3TBLA 2IX2A 3AIZA 2AWAA 4L6PA 2ZVMA 2HIKA 1GE8A 2IZOB 3AIXA 2OD8A 5E0TA 1CZDA 3P87A 2ZVLA 3P83A 2NTIC 2IZOC 5E0UA 1RXZA 1B8HA 3GGRB 3LX1A 2IO4B 4D2GA 3A1JA 3U5ZF 3GGRC 3FDSC 2ZVWA 3GPNA 3V61B 5JNED 3VKXA 1UD9A 2IX2B 2IJXA 4RJFA 2NTIB 2HIKB 2ZVVA 1VYMA 1U76A 1IZ5A 2IX2C 1VYJA 3AIZC 3G65A
chains in the Genus database with same CATH topology
4CS5A 2HIIA 2HIKC 3V60B 3K4XA 1RWZA 1T6LA 1PLQA 3HI8A 5E0VA 5IXAA 3U61F 2Z0LA 5HACA 5DAIA 3A1JB 1U7BA 5DA7A 4L60A 3WGWA 3A1JC 1ISQA 5B7OA 3AIXB 5H0TA 3I2MX 3GPMA 3F1WA 1SXJF 2HIIB 3IFVA 3LX2A 3P91A 1PLRA 2AVTA 3A2FB 1B77A 3G65C 2HIIC 1UL1A 4TR6A 2NTIA 4ZTDA 3U60F 1W60A 5CFKA 3V62B 5IY4A 5A6DA 5IWDA 4YHRA 3GGRA 2IO4A 3HSLX 1AXCA 5AUJA 2ZVKA 1IZ4A 1RXMA 3G65B 1YYPA 3FDSD 4HK1A 1DMLA 3TBLA 2IX2A 3AIZA 2AWAA 4L6PA 2ZVMA 2HIKA 1GE8A 2IZOB 3AIXA 2OD8A 5E0TA 1CZDA 3P87A 2ZVLA 3P83A 2NTIC 2IZOC 5E0UA 1RXZA 1B8HA 3GGRB 3LX1A 2IO4B 4D2GA 3A1JA 3U5ZF 3GGRC 3FDSC 2ZVWA 3GPNA 3V61B 5JNED 3VKXA 1UD9A 2IX2B 2IJXA 4RJFA 2NTIB 2HIKB 2ZVVA 1VYMA 1U76A 1IZ5A 2IX2C 1VYJA 3AIZC 3G65A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CS5 A;  2HII A;  2HIK C;  3V60 B;  3K4X A;  1RWZ A;  1T6L A;  1PLQ A;  3HI8 A;  5E0V A;  5IXA A;  3U61 F;  2Z0L A;  5HAC A;  5DAI A;  3A1J B;  1U7B A;  5DA7 A;  4L60 A;  3WGW A;  3A1J C;  1ISQ A;  5B7O A;  3AIX B;  5H0T A;  3I2M X;  3GPM A;  3F1W A;  1SXJ F;  2HII B;  3IFV A;  3LX2 A;  3P91 A;  1PLR A;  2AVT A;  3A2F B;  1B77 A;  3G65 C;  2HII C;  1UL1 A;  4TR6 A;  2NTI A;  4ZTD A;  3U60 F;  1W60 A;  5CFK A;  3V62 B;  5IY4 A;  5A6D A;  5IWD A;  4YHR A;  3GGR A;  2IO4 A;  3HSL X;  1AXC A;  5AUJ A;  2ZVK A;  1IZ4 A;  1RXM A;  3G65 B;  1YYP A;  3FDS D;  4HK1 A;  1DML A;  3TBL A;  2IX2 A;  3AIZ A;  2AWA A;  4L6P A;  2ZVM A;  2HIK A;  1GE8 A;  2IZO B;  3AIX A;  2OD8 A;  5E0T A;  1CZD A;  3P87 A;  2ZVL A;  3P83 A;  2NTI C;  2IZO C;  5E0U A;  1RXZ A;  1B8H A;  3GGR B;  3LX1 A;  2IO4 B;  4D2G A;  3A1J A;  3U5Z F;  3GGR C;  3FDS C;  2ZVW A;  3GPN A;  3V61 B;  5JNE D;  3VKX A;  1UD9 A;  2IX2 B;  2IJX A;  4RJF A;  2NTI B;  2HIK B;  2ZVV A;  1VYM A;  1U76 A;  1IZ5 A;  2IX2 C;  1VYJ A;  3AIZ C;  3G65 A; 
#chains in the Genus database with same CATH topology
 4CS5 A;  2HII A;  2HIK C;  3V60 B;  3K4X A;  1RWZ A;  1T6L A;  1PLQ A;  3HI8 A;  5E0V A;  5IXA A;  3U61 F;  2Z0L A;  5HAC A;  5DAI A;  3A1J B;  1U7B A;  5DA7 A;  4L60 A;  3WGW A;  3A1J C;  1ISQ A;  5B7O A;  3AIX B;  5H0T A;  3I2M X;  3GPM A;  3F1W A;  1SXJ F;  2HII B;  3IFV A;  3LX2 A;  3P91 A;  1PLR A;  2AVT A;  3A2F B;  1B77 A;  3G65 C;  2HII C;  1UL1 A;  4TR6 A;  2NTI A;  4ZTD A;  3U60 F;  1W60 A;  5CFK A;  3V62 B;  5IY4 A;  5A6D A;  5IWD A;  4YHR A;  3GGR A;  2IO4 A;  3HSL X;  1AXC A;  5AUJ A;  2ZVK A;  1IZ4 A;  1RXM A;  3G65 B;  1YYP A;  3FDS D;  4HK1 A;  1DML A;  3TBL A;  2IX2 A;  3AIZ A;  2AWA A;  4L6P A;  2ZVM A;  2HIK A;  1GE8 A;  2IZO B;  3AIX A;  2OD8 A;  5E0T A;  1CZD A;  3P87 A;  2ZVL A;  3P83 A;  2NTI C;  2IZO C;  5E0U A;  1RXZ A;  1B8H A;  3GGR B;  3LX1 A;  2IO4 B;  4D2G A;  3A1J A;  3U5Z F;  3GGR C;  3FDS C;  2ZVW A;  3GPN A;  3V61 B;  5JNE D;  3VKX A;  1UD9 A;  2IX2 B;  2IJX A;  4RJF A;  2NTI B;  2HIK B;  2ZVV A;  1VYM A;  1U76 A;  1IZ5 A;  2IX2 C;  1VYJ A;  3AIZ C;  3G65 A; 
#chains in the Genus database with same CATH homology
 4CS5 A;  2HII A;  2HIK C;  3V60 B;  3K4X A;  1RWZ A;  1T6L A;  1PLQ A;  3HI8 A;  5E0V A;  5IXA A;  3U61 F;  2Z0L A;  5HAC A;  5DAI A;  3A1J B;  1U7B A;  5DA7 A;  4L60 A;  3WGW A;  3A1J C;  1ISQ A;  5B7O A;  3AIX B;  5H0T A;  3I2M X;  3GPM A;  3F1W A;  1SXJ F;  2HII B;  3IFV A;  3LX2 A;  3P91 A;  1PLR A;  2AVT A;  3A2F B;  1B77 A;  3G65 C;  2HII C;  1UL1 A;  4TR6 A;  2NTI A;  4ZTD A;  3U60 F;  1W60 A;  5CFK A;  3V62 B;  5IY4 A;  5A6D A;  5IWD A;  4YHR A;  3GGR A;  2IO4 A;  3HSL X;  1AXC A;  5AUJ A;  2ZVK A;  1IZ4 A;  1RXM A;  3G65 B;  1YYP A;  3FDS D;  4HK1 A;  1DML A;  3TBL A;  2IX2 A;  3AIZ A;  2AWA A;  4L6P A;  2ZVM A;  2HIK A;  1GE8 A;  2IZO B;  3AIX A;  2OD8 A;  5E0T A;  1CZD A;  3P87 A;  2ZVL A;  3P83 A;  2NTI C;  2IZO C;  5E0U A;  1RXZ A;  1B8H A;  3GGR B;  3LX1 A;  2IO4 B;  4D2G A;  3A1J A;  3U5Z F;  3GGR C;  3FDS C;  2ZVW A;  3GPN A;  3V61 B;  5JNE D;  3VKX A;  1UD9 A;  2IX2 B;  2IJX A;  4RJF A;  2NTI B;  2HIK B;  2ZVV A;  1VYM A;  1U76 A;  1IZ5 A;  2IX2 C;  1VYJ A;  3AIZ C;  3G65 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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