5B7O | Genus

Total Genus 52

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	52
sequence length	289
structure length	248
Chain Sequence	MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVD

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Dna binding protein
source organism	Leishmania donovani
publication title	Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.95 Angstrom resolution. rcsb
molecule keywords	Proliferating cell nuclear antigen
total genus	52
structure length	248
sequence length	289
chains with identical sequence	B, C, D, E, F
ec nomenclature
pdb deposition date	2016-06-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00705	PCNA_N	Proliferating cell nuclear antigen, N-terminal domain
A	PF02747	PCNA_C	Proliferating cell nuclear antigen, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen	Proliferating Cell Nuclear Antigen	5b7oA00

3LX1A 1UD9A 3V62B 3V61B 1CZDA 1T6LA 5B7OA 1DMLA 1W60A 1B8HA 1PLQA 3GGRB 3WGWA 3G65B 1YYPA 3A1JB 2AWAA 5CFKA 3GGRA 2HIKC 3A1JA 1AXCA 2ZVWA 2NTIC 5DAIA 2IX2B 2ZVLA 3GPNA 2HIIA 2IX2A 3AIZC 5IXAA 5JNED 5HACA 1VYMA 5E0VA 5AUJA 3FDSC 1GE8A 3VKXA 4YHRA 4D2GA 4L60A 3U61F 3GPMA 2ZVMA 4HK1A 2IZOB 3G65A 2Z0LA 1SXJF 5A6DA 2IJXA 2HIIC 3K4XA 4L6PA 3FDSD 1RXMA 5E0TA 5DA7A 2IO4B 1B77A 5IWDA 4CS5A 3GGRC 3G65C 2HIKB 3P91A 3A1JC 2IO4A 1U76A 1IZ5A 3AIXB 2NTIB 3P83A 4RJFA 2HIKA 3HSLX 3TBLA 5IY4A 1RXZA 2AVTA 1U7BA 3AIXA 3P87A 2NTIA 1PLRA 5E0UA 3IFVA 2IX2C 1IZ4A 5H0TA 4ZTDA 1ISQA 3F1WA 1UL1A 3AIZA 3U60F 2ZVVA 3U5ZF 3A2FB 1VYJA 1RWZA 4TR6A 3HI8A 3V60B 2ZVKA 2OD8A 2HIIB 3LX2A 2IZOC 3I2MX
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3LX1 A;  1UD9 A;  3V62 B;  3V61 B;  1CZD A;  1T6L A;  5B7O A;  1DML A;  1W60 A;  1B8H A;  1PLQ A;  3GGR B;  3WGW A;  3G65 B;  1YYP A;  3A1J B;  2AWA A;  5CFK A;  3GGR A;  2HIK C;  3A1J A;  1AXC A;  2ZVW A;  2NTI C;  5DAI A;  2IX2 B;  2ZVL A;  3GPN A;  2HII A;  2IX2 A;  3AIZ C;  5IXA A;  5JNE D;  5HAC A;  1VYM A;  5E0V A;  5AUJ A;  3FDS C;  1GE8 A;  3VKX A;  4YHR A;  4D2G A;  4L60 A;  3U61 F;  3GPM A;  2ZVM A;  4HK1 A;  2IZO B;  3G65 A;  2Z0L A;  1SXJ F;  5A6D A;  2IJX A;  2HII C;  3K4X A;  4L6P A;  3FDS D;  1RXM A;  5E0T A;  5DA7 A;  2IO4 B;  1B77 A;  5IWD A;  4CS5 A;  3GGR C;  3G65 C;  2HIK B;  3P91 A;  3A1J C;  2IO4 A;  1U76 A;  1IZ5 A;  3AIX B;  2NTI B;  3P83 A;  4RJF A;  2HIK A;  3HSL X;  3TBL A;  5IY4 A;  1RXZ A;  2AVT A;  1U7B A;  3AIX A;  3P87 A;  2NTI A;  1PLR A;  5E0U A;  3IFV A;  2IX2 C;  1IZ4 A;  5H0T A;  4ZTD A;  1ISQ A;  3F1W A;  1UL1 A;  3AIZ A;  3U60 F;  2ZVV A;  3U5Z F;  3A2F B;  1VYJ A;  1RWZ A;  4TR6 A;  3HI8 A;  3V60 B;  2ZVK A;  2OD8 A;  2HII B;  3LX2 A;  2IZO C;  3I2M X; 
#chains in the Genus database with same CATH topology
 3LX1 A;  1UD9 A;  3V62 B;  3V61 B;  1CZD A;  1T6L A;  5B7O A;  1DML A;  1W60 A;  1B8H A;  1PLQ A;  3GGR B;  3WGW A;  3G65 B;  1YYP A;  3A1J B;  2AWA A;  5CFK A;  3GGR A;  2HIK C;  3A1J A;  1AXC A;  2ZVW A;  2NTI C;  5DAI A;  2IX2 B;  2ZVL A;  3GPN A;  2HII A;  2IX2 A;  3AIZ C;  5IXA A;  5JNE D;  5HAC A;  1VYM A;  5E0V A;  5AUJ A;  3FDS C;  1GE8 A;  3VKX A;  4YHR A;  4D2G A;  4L60 A;  3U61 F;  3GPM A;  2ZVM A;  4HK1 A;  2IZO B;  3G65 A;  2Z0L A;  1SXJ F;  5A6D A;  2IJX A;  2HII C;  3K4X A;  4L6P A;  3FDS D;  1RXM A;  5E0T A;  5DA7 A;  2IO4 B;  1B77 A;  5IWD A;  4CS5 A;  3GGR C;  3G65 C;  2HIK B;  3P91 A;  3A1J C;  2IO4 A;  1U76 A;  1IZ5 A;  3AIX B;  2NTI B;  3P83 A;  4RJF A;  2HIK A;  3HSL X;  3TBL A;  5IY4 A;  1RXZ A;  2AVT A;  1U7B A;  3AIX A;  3P87 A;  2NTI A;  1PLR A;  5E0U A;  3IFV A;  2IX2 C;  1IZ4 A;  5H0T A;  4ZTD A;  1ISQ A;  3F1W A;  1UL1 A;  3AIZ A;  3U60 F;  2ZVV A;  3U5Z F;  3A2F B;  1VYJ A;  1RWZ A;  4TR6 A;  3HI8 A;  3V60 B;  2ZVK A;  2OD8 A;  2HII B;  3LX2 A;  2IZO C;  3I2M X; 
#chains in the Genus database with same CATH homology
 3LX1 A;  1UD9 A;  3V62 B;  3V61 B;  1CZD A;  1T6L A;  5B7O A;  1DML A;  1W60 A;  1B8H A;  1PLQ A;  3GGR B;  3WGW A;  3G65 B;  1YYP A;  3A1J B;  2AWA A;  5CFK A;  3GGR A;  2HIK C;  3A1J A;  1AXC A;  2ZVW A;  2NTI C;  5DAI A;  2IX2 B;  2ZVL A;  3GPN A;  2HII A;  2IX2 A;  3AIZ C;  5IXA A;  5JNE D;  5HAC A;  1VYM A;  5E0V A;  5AUJ A;  3FDS C;  1GE8 A;  3VKX A;  4YHR A;  4D2G A;  4L60 A;  3U61 F;  3GPM A;  2ZVM A;  4HK1 A;  2IZO B;  3G65 A;  2Z0L A;  1SXJ F;  5A6D A;  2IJX A;  2HII C;  3K4X A;  4L6P A;  3FDS D;  1RXM A;  5E0T A;  5DA7 A;  2IO4 B;  1B77 A;  5IWD A;  4CS5 A;  3GGR C;  3G65 C;  2HIK B;  3P91 A;  3A1J C;  2IO4 A;  1U76 A;  1IZ5 A;  3AIX B;  2NTI B;  3P83 A;  4RJF A;  2HIK A;  3HSL X;  3TBL A;  5IY4 A;  1RXZ A;  2AVT A;  1U7B A;  3AIX A;  3P87 A;  2NTI A;  1PLR A;  5E0U A;  3IFV A;  2IX2 C;  1IZ4 A;  5H0T A;  4ZTD A;  1ISQ A;  3F1W A;  1UL1 A;  3AIZ A;  3U60 F;  2ZVV A;  3U5Z F;  3A2F B;  1VYJ A;  1RWZ A;  4TR6 A;  3HI8 A;  3V60 B;  2ZVK A;  2OD8 A;  2HII B;  3LX2 A;  2IZO C;  3I2M X;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5B7OA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations