5CFKA

Crystal structure of proliferating cell nuclear antigen from leishmania donovani at 3.2 a resolution
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
256
structure length
253
Chain Sequence
MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVSDRGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 3.2 A resolution
rcsb
molecule tags Dna binding protein
source organism Leishmania donovani
molecule keywords Proliferating cell nuclear antigen,Proliferating cell nuclea
total genus 49
structure length 253
sequence length 256
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2015-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5cfkA00
2ZVVA 2IX2C 3A1JB 3AIZC 3A1JC 3GPMA 3F1WA 3GGRA 3HI8A 3V61B 3GGRB 4ZTDA 2ZVMA 5B7OA 1B77A 2ZVWA 3P87A 1RXMA 3FDSD 1YYPA 4RJFA 3U5ZF 5E0TA 2HIKA 1SXJF 1VYMA 1IZ5A 1IZ4A 4YHRA 2HIKB 3V62B 2IO4A 2HIKC 3VKXA 1PLQA 3LX1A 2IO4B 2IX2B 5A6DA 2AVTA 1U76A 3IFVA 3TBLA 3P83A 4L60A 2IZOB 1B8HA 2IZOC 3V60B 5IWDA 3HSLX 5IXAA 2OD8A 4TR6A 5AUJA 2AWAA 3A2FB 2IJXA 1CZDA 3P91A 5IY4A 1VYJA 1DMLA 1W60A 2NTIA 2ZVLA 5CFKA 5E0UA 2NTIB 1GE8A 3FDSC 2NTIC 5HACA 5E0VA 4CS5A 3I2MX 3AIXA 2HIIA 3WGWA 1RXZA 4HK1A 3AIXB 5JNED 2HIIB 1UL1A 3GPNA 2HIIC 5DAIA 2ZVKA 1UD9A 4D2GA 4L6PA 2Z0LA 1PLRA 1T6LA 3G65A 3GGRC 3U60F 5DA7A 5H0TA 1U7BA 2IX2A 1ISQA 3G65B 3AIZA 1AXCA 1RWZA 3A1JA 3G65C 3K4XA 3U61F 3LX2A
chains in the Genus database with same CATH superfamily
2ZVVA 2IX2C 3A1JB 3AIZC 3A1JC 3GPMA 3F1WA 3GGRA 3HI8A 3V61B 3GGRB 4ZTDA 2ZVMA 5B7OA 1B77A 2ZVWA 3P87A 1RXMA 3FDSD 1YYPA 4RJFA 3U5ZF 5E0TA 2HIKA 1SXJF 1VYMA 1IZ5A 1IZ4A 4YHRA 2HIKB 3V62B 2IO4A 2HIKC 3VKXA 1PLQA 3LX1A 2IO4B 2IX2B 5A6DA 2AVTA 1U76A 3IFVA 3TBLA 3P83A 4L60A 2IZOB 1B8HA 2IZOC 3V60B 5IWDA 3HSLX 5IXAA 2OD8A 4TR6A 5AUJA 2AWAA 3A2FB 2IJXA 1CZDA 3P91A 5IY4A 1VYJA 1DMLA 1W60A 2NTIA 2ZVLA 5CFKA 5E0UA 2NTIB 1GE8A 3FDSC 2NTIC 5HACA 5E0VA 4CS5A 3I2MX 3AIXA 2HIIA 3WGWA 1RXZA 4HK1A 3AIXB 5JNED 2HIIB 1UL1A 3GPNA 2HIIC 5DAIA 2ZVKA 1UD9A 4D2GA 4L6PA 2Z0LA 1PLRA 1T6LA 3G65A 3GGRC 3U60F 5DA7A 5H0TA 1U7BA 2IX2A 1ISQA 3G65B 3AIZA 1AXCA 1RWZA 3A1JA 3G65C 3K4XA 3U61F 3LX2A
chains in the Genus database with same CATH topology
2ZVVA 2IX2C 3A1JB 3AIZC 3A1JC 3GPMA 3F1WA 3GGRA 3HI8A 3V61B 3GGRB 4ZTDA 2ZVMA 5B7OA 1B77A 2ZVWA 3P87A 1RXMA 3FDSD 1YYPA 4RJFA 3U5ZF 5E0TA 2HIKA 1SXJF 1VYMA 1IZ5A 1IZ4A 4YHRA 2HIKB 3V62B 2IO4A 2HIKC 3VKXA 1PLQA 3LX1A 2IO4B 2IX2B 5A6DA 2AVTA 1U76A 3IFVA 3TBLA 3P83A 4L60A 2IZOB 1B8HA 2IZOC 3V60B 5IWDA 3HSLX 5IXAA 2OD8A 4TR6A 5AUJA 2AWAA 3A2FB 2IJXA 1CZDA 3P91A 5IY4A 1VYJA 1DMLA 1W60A 2NTIA 2ZVLA 5CFKA 5E0UA 2NTIB 1GE8A 3FDSC 2NTIC 5HACA 5E0VA 4CS5A 3I2MX 3AIXA 2HIIA 3WGWA 1RXZA 4HK1A 3AIXB 5JNED 2HIIB 1UL1A 3GPNA 2HIIC 5DAIA 2ZVKA 1UD9A 4D2GA 4L6PA 2Z0LA 1PLRA 1T6LA 3G65A 3GGRC 3U60F 5DA7A 5H0TA 1U7BA 2IX2A 1ISQA 3G65B 3AIZA 1AXCA 1RWZA 3A1JA 3G65C 3K4XA 3U61F 3LX2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVV A;  2IX2 C;  3A1J B;  3AIZ C;  3A1J C;  3GPM A;  3F1W A;  3GGR A;  3HI8 A;  3V61 B;  3GGR B;  4ZTD A;  2ZVM A;  5B7O A;  1B77 A;  2ZVW A;  3P87 A;  1RXM A;  3FDS D;  1YYP A;  4RJF A;  3U5Z F;  5E0T A;  2HIK A;  1SXJ F;  1VYM A;  1IZ5 A;  1IZ4 A;  4YHR A;  2HIK B;  3V62 B;  2IO4 A;  2HIK C;  3VKX A;  1PLQ A;  3LX1 A;  2IO4 B;  2IX2 B;  5A6D A;  2AVT A;  1U76 A;  3IFV A;  3TBL A;  3P83 A;  4L60 A;  2IZO B;  1B8H A;  2IZO C;  3V60 B;  5IWD A;  3HSL X;  5IXA A;  2OD8 A;  4TR6 A;  5AUJ A;  2AWA A;  3A2F B;  2IJX A;  1CZD A;  3P91 A;  5IY4 A;  1VYJ A;  1DML A;  1W60 A;  2NTI A;  2ZVL A;  5CFK A;  5E0U A;  2NTI B;  1GE8 A;  3FDS C;  2NTI C;  5HAC A;  5E0V A;  4CS5 A;  3I2M X;  3AIX A;  2HII A;  3WGW A;  1RXZ A;  4HK1 A;  3AIX B;  5JNE D;  2HII B;  1UL1 A;  3GPN A;  2HII C;  5DAI A;  2ZVK A;  1UD9 A;  4D2G A;  4L6P A;  2Z0L A;  1PLR A;  1T6L A;  3G65 A;  3GGR C;  3U60 F;  5DA7 A;  5H0T A;  1U7B A;  2IX2 A;  1ISQ A;  3G65 B;  3AIZ A;  1AXC A;  1RWZ A;  3A1J A;  3G65 C;  3K4X A;  3U61 F;  3LX2 A; 
#chains in the Genus database with same CATH topology
 2ZVV A;  2IX2 C;  3A1J B;  3AIZ C;  3A1J C;  3GPM A;  3F1W A;  3GGR A;  3HI8 A;  3V61 B;  3GGR B;  4ZTD A;  2ZVM A;  5B7O A;  1B77 A;  2ZVW A;  3P87 A;  1RXM A;  3FDS D;  1YYP A;  4RJF A;  3U5Z F;  5E0T A;  2HIK A;  1SXJ F;  1VYM A;  1IZ5 A;  1IZ4 A;  4YHR A;  2HIK B;  3V62 B;  2IO4 A;  2HIK C;  3VKX A;  1PLQ A;  3LX1 A;  2IO4 B;  2IX2 B;  5A6D A;  2AVT A;  1U76 A;  3IFV A;  3TBL A;  3P83 A;  4L60 A;  2IZO B;  1B8H A;  2IZO C;  3V60 B;  5IWD A;  3HSL X;  5IXA A;  2OD8 A;  4TR6 A;  5AUJ A;  2AWA A;  3A2F B;  2IJX A;  1CZD A;  3P91 A;  5IY4 A;  1VYJ A;  1DML A;  1W60 A;  2NTI A;  2ZVL A;  5CFK A;  5E0U A;  2NTI B;  1GE8 A;  3FDS C;  2NTI C;  5HAC A;  5E0V A;  4CS5 A;  3I2M X;  3AIX A;  2HII A;  3WGW A;  1RXZ A;  4HK1 A;  3AIX B;  5JNE D;  2HII B;  1UL1 A;  3GPN A;  2HII C;  5DAI A;  2ZVK A;  1UD9 A;  4D2G A;  4L6P A;  2Z0L A;  1PLR A;  1T6L A;  3G65 A;  3GGR C;  3U60 F;  5DA7 A;  5H0T A;  1U7B A;  2IX2 A;  1ISQ A;  3G65 B;  3AIZ A;  1AXC A;  1RWZ A;  3A1J A;  3G65 C;  3K4X A;  3U61 F;  3LX2 A; 
#chains in the Genus database with same CATH homology
 2ZVV A;  2IX2 C;  3A1J B;  3AIZ C;  3A1J C;  3GPM A;  3F1W A;  3GGR A;  3HI8 A;  3V61 B;  3GGR B;  4ZTD A;  2ZVM A;  5B7O A;  1B77 A;  2ZVW A;  3P87 A;  1RXM A;  3FDS D;  1YYP A;  4RJF A;  3U5Z F;  5E0T A;  2HIK A;  1SXJ F;  1VYM A;  1IZ5 A;  1IZ4 A;  4YHR A;  2HIK B;  3V62 B;  2IO4 A;  2HIK C;  3VKX A;  1PLQ A;  3LX1 A;  2IO4 B;  2IX2 B;  5A6D A;  2AVT A;  1U76 A;  3IFV A;  3TBL A;  3P83 A;  4L60 A;  2IZO B;  1B8H A;  2IZO C;  3V60 B;  5IWD A;  3HSL X;  5IXA A;  2OD8 A;  4TR6 A;  5AUJ A;  2AWA A;  3A2F B;  2IJX A;  1CZD A;  3P91 A;  5IY4 A;  1VYJ A;  1DML A;  1W60 A;  2NTI A;  2ZVL A;  5CFK A;  5E0U A;  2NTI B;  1GE8 A;  3FDS C;  2NTI C;  5HAC A;  5E0V A;  4CS5 A;  3I2M X;  3AIX A;  2HII A;  3WGW A;  1RXZ A;  4HK1 A;  3AIX B;  5JNE D;  2HII B;  1UL1 A;  3GPN A;  2HII C;  5DAI A;  2ZVK A;  1UD9 A;  4D2G A;  4L6P A;  2Z0L A;  1PLR A;  1T6L A;  3G65 A;  3GGR C;  3U60 F;  5DA7 A;  5H0T A;  1U7B A;  2IX2 A;  1ISQ A;  3G65 B;  3AIZ A;  1AXC A;  1RWZ A;  3A1J A;  3G65 C;  3K4X A;  3U61 F;  3LX2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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