5D8CA

Crystal structure of hinmlr, a merr family regulator lacking the sensor domain, bound to promoter dna
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
126
structure length
126
Chain Sequence
MTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNTGMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAKALGSVKAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region.
pubmed doi rcsb
molecule keywords MerR family regulator protein
molecule tags Transcription/dna
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
total genus 47
structure length 126
sequence length 126
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 5d8cA00
3Q2YA 3UCSA 1R8DA 1EXIA 2ZHGA 1Q09A 3D6ZA 1Q07A 2DG6A 2ZHHA 2JMLA 3Q3DA 5I44A 4WLWA 3Q1MA 1Q08A 5I41B 1R8EA 1Q0AA 3Q5RA 3D70A 2VZ4A 5D90A 4R22B 3Q5PA 3QAOA 5D8CA 3IAOA 4R4EA 1Q06A 1EXJA 1Q05A 3D6YA 4J2NA 1JBGA 4WLSA 3GPVA 3GP4A 3HH0A 3D71A 3Q5SA 4R24B 5E01A
chains in the Genus database with same CATH superfamily
3Q2YA 3UCSA 1R8DA 1EXIA 2ZHGA 1Q09A 3D6ZA 1Q07A 3EZ9A 3EZ2A 2DG6A 4LHFA 2ZHHA 2JMLA 3Q3DA 5I44A 4WLWA 3Q1MA 1Q08A 2OG0A 5I41B 1LX8A 1R8EA 3EZ7A 2IEFA 1Q0AA 3Q5RA 1Y6UA 3D70A 2VZ4A 5D90A 4R22B 3Q5PA 3QAOA 5D8CA 3IAOA 3EZFA 1Q06A 4R4EA 4DCZA 1EXJA 1PM6A 1Q05A 1RH6A 4J2NA 1JBGA 3D6YA 4WLSA 3GPVA 3GP4A 3EZ6A 2KVVA 3HH0A 3D71A 3Q5SA 4R24B 5E01A
chains in the Genus database with same CATH topology
3Q2YA 3UCSA 1R8DA 1EXIA 2ZHGA 1Q09A 3D6ZA 1Q07A 3EZ9A 3EZ2A 2DG6A 4LHFA 2ZHHA 2JMLA 3Q3DA 5I44A 4WLWA 3Q1MA 1Q08A 2OG0A 5I41B 1LX8A 1R8EA 3EZ7A 2IEFA 1Q0AA 3Q5RA 1Y6UA 3D70A 2VZ4A 5D90A 4R22B 3Q5PA 3QAOA 5D8CA 3IAOA 3EZFA 1Q06A 4R4EA 4DCZA 1EXJA 1PM6A 1Q05A 1RH6A 4J2NA 1JBGA 3D6YA 4WLSA 3GPVA 3GP4A 3EZ6A 2KVVA 3HH0A 3D71A 3Q5SA 4R24B 5E01A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q2Y A;  3UCS A;  1R8D A;  1EXI A;  2ZHG A;  1Q09 A;  3D6Z A;  1Q07 A;  2DG6 A;  2ZHH A;  2JML A;  3Q3D A;  5I44 A;  4WLW A;  3Q1M A;  1Q08 A;  5I41 B;  1R8E A;  1Q0A A;  3Q5R A;  3D70 A;  2VZ4 A;  5D90 A;  4R22 B;  3Q5P A;  3QAO A;  5D8C A;  3IAO A;  4R4E A;  1Q06 A;  1EXJ A;  1Q05 A;  3D6Y A;  4J2N A;  1JBG A;  4WLS A;  3GPV A;  3GP4 A;  3HH0 A;  3D71 A;  3Q5S A;  4R24 B;  5E01 A; 
#chains in the Genus database with same CATH topology
 3Q2Y A;  3UCS A;  1R8D A;  1EXI A;  2ZHG A;  1Q09 A;  3D6Z A;  1Q07 A;  3EZ9 A;  3EZ2 A;  2DG6 A;  4LHF A;  2ZHH A;  2JML A;  3Q3D A;  5I44 A;  4WLW A;  3Q1M A;  1Q08 A;  2OG0 A;  5I41 B;  1LX8 A;  1R8E A;  3EZ7 A;  2IEF A;  1Q0A A;  3Q5R A;  1Y6U A;  3D70 A;  2VZ4 A;  5D90 A;  4R22 B;  3Q5P A;  3QAO A;  5D8C A;  3IAO A;  3EZF A;  1Q06 A;  4R4E A;  4DCZ A;  1EXJ A;  1PM6 A;  1Q05 A;  1RH6 A;  4J2N A;  1JBG A;  3D6Y A;  4WLS A;  3GPV A;  3GP4 A;  3EZ6 A;  2KVV A;  3HH0 A;  3D71 A;  3Q5S A;  4R24 B;  5E01 A; 
#chains in the Genus database with same CATH homology
 3Q2Y A;  3UCS A;  1R8D A;  1EXI A;  2ZHG A;  1Q09 A;  3D6Z A;  1Q07 A;  3EZ9 A;  3EZ2 A;  2DG6 A;  4LHF A;  2ZHH A;  2JML A;  3Q3D A;  5I44 A;  4WLW A;  3Q1M A;  1Q08 A;  2OG0 A;  5I41 B;  1LX8 A;  1R8E A;  3EZ7 A;  2IEF A;  1Q0A A;  3Q5R A;  1Y6U A;  3D70 A;  2VZ4 A;  5D90 A;  4R22 B;  3Q5P A;  3QAO A;  5D8C A;  3IAO A;  3EZF A;  1Q06 A;  4R4E A;  4DCZ A;  1EXJ A;  1PM6 A;  1Q05 A;  1RH6 A;  4J2N A;  1JBG A;  3D6Y A;  4WLS A;  3GPV A;  3GP4 A;  3EZ6 A;  2KVV A;  3HH0 A;  3D71 A;  3Q5S A;  4R24 B;  5E01 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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