5H0TA

Crystal structure of proliferating cell nuclear antigen from leishmania donovani at 2.73 angstrom resolution
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
289
structure length
248
Chain Sequence
MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Leishmania donovani
molecule keywords Proliferating cell nuclear antigen
total genus 56
structure length 248
sequence length 289
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2016-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5h0tA00
2ZVVA 1T6LA 3U60F 5CFKA 3V60B 3TBLA 3AIXB 1U7BA 1ISQA 4CS5A 1B8HA 5E0TA 3G65B 3FDSD 1U76A 2IZOC 3U5ZF 1W60A 2NTIB 2OD8A 2ZVMA 5B7OA 5DA7A 1IZ4A 3IFVA 3FDSC 1GE8A 2HIKA 3HSLX 3I2MX 2HIIA 5H0TA 2HIKC 3GPNA 3LX2A 1RXMA 2HIIC 1PLRA 2IO4A 3P91A 1PLQA 2IJXA 5A6DA 5IY4A 3GGRA 5JNED 4RJFA 1AXCA 2IX2B 2ZVLA 3LX1A 2ZVWA 4L60A 4ZTDA 4D2GA 3GGRC 3F1WA 3U61F 1UL1A 2AVTA 2AWAA 3GPMA 3HI8A 3VKXA 3AIXA 1UD9A 3P83A 1DMLA 1YYPA 2IZOB 5E0UA 3G65A 3A1JB 1B77A 3P87A 3G65C 3WGWA 2IX2A 2NTIA 4L6PA 1IZ5A 5E0VA 2IX2C 1VYJA 5IXAA 2NTIC 1SXJF 2Z0LA 2HIKB 3V62B 4HK1A 1RXZA 3AIZA 2HIIB 5HACA 1CZDA 3AIZC 5IWDA 5DAIA 3V61B 1VYMA 2IO4B 3A1JA 3K4XA 3A2FB 2ZVKA 3GGRB 4TR6A 4YHRA 3A1JC 1RWZA 5AUJA
chains in the Genus database with same CATH superfamily
2ZVVA 1T6LA 3U60F 5CFKA 3V60B 3TBLA 3AIXB 1U7BA 1ISQA 4CS5A 1B8HA 5E0TA 3G65B 3FDSD 1U76A 2IZOC 3U5ZF 1W60A 2NTIB 2OD8A 2ZVMA 5B7OA 5DA7A 1IZ4A 3IFVA 3FDSC 1GE8A 2HIKA 3HSLX 3I2MX 2HIIA 5H0TA 2HIKC 3GPNA 3LX2A 1RXMA 2HIIC 1PLRA 2IO4A 3P91A 1PLQA 2IJXA 5A6DA 5IY4A 3GGRA 5JNED 4RJFA 1AXCA 2IX2B 2ZVLA 3LX1A 2ZVWA 4L60A 4ZTDA 4D2GA 3GGRC 3F1WA 3U61F 1UL1A 2AVTA 2AWAA 3GPMA 3HI8A 3VKXA 3AIXA 1UD9A 3P83A 1DMLA 1YYPA 2IZOB 5E0UA 3G65A 3A1JB 1B77A 3P87A 3G65C 3WGWA 2IX2A 2NTIA 4L6PA 1IZ5A 5E0VA 2IX2C 1VYJA 5IXAA 2NTIC 1SXJF 2Z0LA 2HIKB 3V62B 4HK1A 1RXZA 3AIZA 2HIIB 5HACA 1CZDA 3AIZC 5IWDA 5DAIA 3V61B 1VYMA 2IO4B 3A1JA 3K4XA 3A2FB 2ZVKA 3GGRB 4TR6A 4YHRA 3A1JC 1RWZA 5AUJA
chains in the Genus database with same CATH topology
2ZVVA 1T6LA 3U60F 5CFKA 3V60B 3TBLA 3AIXB 1U7BA 1ISQA 4CS5A 1B8HA 5E0TA 3G65B 3FDSD 1U76A 2IZOC 3U5ZF 1W60A 2NTIB 2OD8A 2ZVMA 5B7OA 5DA7A 1IZ4A 3IFVA 3FDSC 1GE8A 2HIKA 3HSLX 3I2MX 2HIIA 5H0TA 2HIKC 3GPNA 3LX2A 1RXMA 2HIIC 1PLRA 2IO4A 3P91A 1PLQA 2IJXA 5A6DA 5IY4A 3GGRA 5JNED 4RJFA 1AXCA 2IX2B 2ZVLA 3LX1A 2ZVWA 4L60A 4ZTDA 4D2GA 3GGRC 3F1WA 3U61F 1UL1A 2AVTA 2AWAA 3GPMA 3HI8A 3VKXA 3AIXA 1UD9A 3P83A 1DMLA 1YYPA 2IZOB 5E0UA 3G65A 3A1JB 1B77A 3P87A 3G65C 3WGWA 2IX2A 2NTIA 4L6PA 1IZ5A 5E0VA 2IX2C 1VYJA 5IXAA 2NTIC 1SXJF 2Z0LA 2HIKB 3V62B 4HK1A 1RXZA 3AIZA 2HIIB 5HACA 1CZDA 3AIZC 5IWDA 5DAIA 3V61B 1VYMA 2IO4B 3A1JA 3K4XA 3A2FB 2ZVKA 3GGRB 4TR6A 4YHRA 3A1JC 1RWZA 5AUJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZVV A;  1T6L A;  3U60 F;  5CFK A;  3V60 B;  3TBL A;  3AIX B;  1U7B A;  1ISQ A;  4CS5 A;  1B8H A;  5E0T A;  3G65 B;  3FDS D;  1U76 A;  2IZO C;  3U5Z F;  1W60 A;  2NTI B;  2OD8 A;  2ZVM A;  5B7O A;  5DA7 A;  1IZ4 A;  3IFV A;  3FDS C;  1GE8 A;  2HIK A;  3HSL X;  3I2M X;  2HII A;  5H0T A;  2HIK C;  3GPN A;  3LX2 A;  1RXM A;  2HII C;  1PLR A;  2IO4 A;  3P91 A;  1PLQ A;  2IJX A;  5A6D A;  5IY4 A;  3GGR A;  5JNE D;  4RJF A;  1AXC A;  2IX2 B;  2ZVL A;  3LX1 A;  2ZVW A;  4L60 A;  4ZTD A;  4D2G A;  3GGR C;  3F1W A;  3U61 F;  1UL1 A;  2AVT A;  2AWA A;  3GPM A;  3HI8 A;  3VKX A;  3AIX A;  1UD9 A;  3P83 A;  1DML A;  1YYP A;  2IZO B;  5E0U A;  3G65 A;  3A1J B;  1B77 A;  3P87 A;  3G65 C;  3WGW A;  2IX2 A;  2NTI A;  4L6P A;  1IZ5 A;  5E0V A;  2IX2 C;  1VYJ A;  5IXA A;  2NTI C;  1SXJ F;  2Z0L A;  2HIK B;  3V62 B;  4HK1 A;  1RXZ A;  3AIZ A;  2HII B;  5HAC A;  1CZD A;  3AIZ C;  5IWD A;  5DAI A;  3V61 B;  1VYM A;  2IO4 B;  3A1J A;  3K4X A;  3A2F B;  2ZVK A;  3GGR B;  4TR6 A;  4YHR A;  3A1J C;  1RWZ A;  5AUJ A; 
#chains in the Genus database with same CATH topology
 2ZVV A;  1T6L A;  3U60 F;  5CFK A;  3V60 B;  3TBL A;  3AIX B;  1U7B A;  1ISQ A;  4CS5 A;  1B8H A;  5E0T A;  3G65 B;  3FDS D;  1U76 A;  2IZO C;  3U5Z F;  1W60 A;  2NTI B;  2OD8 A;  2ZVM A;  5B7O A;  5DA7 A;  1IZ4 A;  3IFV A;  3FDS C;  1GE8 A;  2HIK A;  3HSL X;  3I2M X;  2HII A;  5H0T A;  2HIK C;  3GPN A;  3LX2 A;  1RXM A;  2HII C;  1PLR A;  2IO4 A;  3P91 A;  1PLQ A;  2IJX A;  5A6D A;  5IY4 A;  3GGR A;  5JNE D;  4RJF A;  1AXC A;  2IX2 B;  2ZVL A;  3LX1 A;  2ZVW A;  4L60 A;  4ZTD A;  4D2G A;  3GGR C;  3F1W A;  3U61 F;  1UL1 A;  2AVT A;  2AWA A;  3GPM A;  3HI8 A;  3VKX A;  3AIX A;  1UD9 A;  3P83 A;  1DML A;  1YYP A;  2IZO B;  5E0U A;  3G65 A;  3A1J B;  1B77 A;  3P87 A;  3G65 C;  3WGW A;  2IX2 A;  2NTI A;  4L6P A;  1IZ5 A;  5E0V A;  2IX2 C;  1VYJ A;  5IXA A;  2NTI C;  1SXJ F;  2Z0L A;  2HIK B;  3V62 B;  4HK1 A;  1RXZ A;  3AIZ A;  2HII B;  5HAC A;  1CZD A;  3AIZ C;  5IWD A;  5DAI A;  3V61 B;  1VYM A;  2IO4 B;  3A1J A;  3K4X A;  3A2F B;  2ZVK A;  3GGR B;  4TR6 A;  4YHR A;  3A1J C;  1RWZ A;  5AUJ A; 
#chains in the Genus database with same CATH homology
 2ZVV A;  1T6L A;  3U60 F;  5CFK A;  3V60 B;  3TBL A;  3AIX B;  1U7B A;  1ISQ A;  4CS5 A;  1B8H A;  5E0T A;  3G65 B;  3FDS D;  1U76 A;  2IZO C;  3U5Z F;  1W60 A;  2NTI B;  2OD8 A;  2ZVM A;  5B7O A;  5DA7 A;  1IZ4 A;  3IFV A;  3FDS C;  1GE8 A;  2HIK A;  3HSL X;  3I2M X;  2HII A;  5H0T A;  2HIK C;  3GPN A;  3LX2 A;  1RXM A;  2HII C;  1PLR A;  2IO4 A;  3P91 A;  1PLQ A;  2IJX A;  5A6D A;  5IY4 A;  3GGR A;  5JNE D;  4RJF A;  1AXC A;  2IX2 B;  2ZVL A;  3LX1 A;  2ZVW A;  4L60 A;  4ZTD A;  4D2G A;  3GGR C;  3F1W A;  3U61 F;  1UL1 A;  2AVT A;  2AWA A;  3GPM A;  3HI8 A;  3VKX A;  3AIX A;  1UD9 A;  3P83 A;  1DML A;  1YYP A;  2IZO B;  5E0U A;  3G65 A;  3A1J B;  1B77 A;  3P87 A;  3G65 C;  3WGW A;  2IX2 A;  2NTI A;  4L6P A;  1IZ5 A;  5E0V A;  2IX2 C;  1VYJ A;  5IXA A;  2NTI C;  1SXJ F;  2Z0L A;  2HIK B;  3V62 B;  4HK1 A;  1RXZ A;  3AIZ A;  2HII B;  5HAC A;  1CZD A;  3AIZ C;  5IWD A;  5DAI A;  3V61 B;  1VYM A;  2IO4 B;  3A1J A;  3K4X A;  3A2F B;  2ZVK A;  3GGR B;  4TR6 A;  4YHR A;  3A1J C;  1RWZ A;  5AUJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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