5HACA

Crystal structure of proliferating cell nuclear antigen from leishmania donovani at 2.95 a resolution
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
296
structure length
260
Chain Sequence
LVPRGSHMLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVSDRGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution
rcsb
molecule tags Dna binding protein
source organism Leishmania donovani
molecule keywords Proliferating cell nuclear antigen
total genus 50
structure length 260
sequence length 296
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2015-12-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5hacA00
3G65B 1U7BA 3P83A 3LX2A 1YYPA 1B77A 1IZ4A 5E0TA 3AIZC 2Z0LA 3P87A 1SXJF 3U5ZF 3GGRB 5E0VA 4CS5A 3P91A 5IXAA 3WGWA 1VYJA 3TBLA 2IX2C 3FDSD 5DA7A 2HIIC 3GPMA 5IWDA 1CZDA 2IX2A 2IO4B 5H0TA 3HSLX 1ISQA 2HIKC 2NTIC 2IZOB 1RWZA 2ZVWA 2HIKA 5DAIA 2NTIA 5JNED 1AXCA 3AIZA 1U76A 3GGRC 1PLRA 2ZVVA 3U61F 3I2MX 5E0UA 3A1JC 1IZ5A 1GE8A 1B8HA 4HK1A 3AIXA 4ZTDA 2HIIA 4TR6A 2IX2B 2AVTA 3A1JA 3G65C 2ZVLA 1UL1A 3A2FB 3VKXA 2AWAA 3V61B 3G65A 1VYMA 2HIKB 3HI8A 2NTIB 1RXMA 2ZVMA 4YHRA 3V60B 3LX1A 5A6DA 3GGRA 2OD8A 4RJFA 4D2GA 1RXZA 3U60F 2IJXA 1UD9A 5B7OA 3AIXB 2HIIB 5HACA 5CFKA 5AUJA 3IFVA 3A1JB 3F1WA 3FDSC 1DMLA 3GPNA 2IO4A 2IZOC 3V62B 4L6PA 4L60A 1W60A 5IY4A 1PLQA 3K4XA 2ZVKA 1T6LA
chains in the Genus database with same CATH superfamily
3G65B 1U7BA 3P83A 3LX2A 1YYPA 1B77A 1IZ4A 5E0TA 3AIZC 2Z0LA 3P87A 1SXJF 3U5ZF 3GGRB 5E0VA 4CS5A 3P91A 5IXAA 3WGWA 1VYJA 3TBLA 2IX2C 3FDSD 5DA7A 2HIIC 3GPMA 5IWDA 1CZDA 2IX2A 2IO4B 5H0TA 3HSLX 1ISQA 2HIKC 2NTIC 2IZOB 1RWZA 2ZVWA 2HIKA 5DAIA 2NTIA 5JNED 1AXCA 3AIZA 1U76A 3GGRC 1PLRA 2ZVVA 3U61F 3I2MX 5E0UA 3A1JC 1IZ5A 1GE8A 1B8HA 4HK1A 3AIXA 4ZTDA 2HIIA 4TR6A 2IX2B 2AVTA 3A1JA 3G65C 2ZVLA 1UL1A 3A2FB 3VKXA 2AWAA 3V61B 3G65A 1VYMA 2HIKB 3HI8A 2NTIB 1RXMA 2ZVMA 4YHRA 3V60B 3LX1A 5A6DA 3GGRA 2OD8A 4RJFA 4D2GA 1RXZA 3U60F 2IJXA 1UD9A 5B7OA 3AIXB 2HIIB 5HACA 5CFKA 5AUJA 3IFVA 3A1JB 3F1WA 3FDSC 1DMLA 3GPNA 2IO4A 2IZOC 3V62B 4L6PA 4L60A 1W60A 5IY4A 1PLQA 3K4XA 2ZVKA 1T6LA
chains in the Genus database with same CATH topology
3G65B 1U7BA 3P83A 3LX2A 1YYPA 1B77A 1IZ4A 5E0TA 3AIZC 2Z0LA 3P87A 1SXJF 3U5ZF 3GGRB 5E0VA 4CS5A 3P91A 5IXAA 3WGWA 1VYJA 3TBLA 2IX2C 3FDSD 5DA7A 2HIIC 3GPMA 5IWDA 1CZDA 2IX2A 2IO4B 5H0TA 3HSLX 1ISQA 2HIKC 2NTIC 2IZOB 1RWZA 2ZVWA 2HIKA 5DAIA 2NTIA 5JNED 1AXCA 3AIZA 1U76A 3GGRC 1PLRA 2ZVVA 3U61F 3I2MX 5E0UA 3A1JC 1IZ5A 1GE8A 1B8HA 4HK1A 3AIXA 4ZTDA 2HIIA 4TR6A 2IX2B 2AVTA 3A1JA 3G65C 2ZVLA 1UL1A 3A2FB 3VKXA 2AWAA 3V61B 3G65A 1VYMA 2HIKB 3HI8A 2NTIB 1RXMA 2ZVMA 4YHRA 3V60B 3LX1A 5A6DA 3GGRA 2OD8A 4RJFA 4D2GA 1RXZA 3U60F 2IJXA 1UD9A 5B7OA 3AIXB 2HIIB 5HACA 5CFKA 5AUJA 3IFVA 3A1JB 3F1WA 3FDSC 1DMLA 3GPNA 2IO4A 2IZOC 3V62B 4L6PA 4L60A 1W60A 5IY4A 1PLQA 3K4XA 2ZVKA 1T6LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G65 B;  1U7B A;  3P83 A;  3LX2 A;  1YYP A;  1B77 A;  1IZ4 A;  5E0T A;  3AIZ C;  2Z0L A;  3P87 A;  1SXJ F;  3U5Z F;  3GGR B;  5E0V A;  4CS5 A;  3P91 A;  5IXA A;  3WGW A;  1VYJ A;  3TBL A;  2IX2 C;  3FDS D;  5DA7 A;  2HII C;  3GPM A;  5IWD A;  1CZD A;  2IX2 A;  2IO4 B;  5H0T A;  3HSL X;  1ISQ A;  2HIK C;  2NTI C;  2IZO B;  1RWZ A;  2ZVW A;  2HIK A;  5DAI A;  2NTI A;  5JNE D;  1AXC A;  3AIZ A;  1U76 A;  3GGR C;  1PLR A;  2ZVV A;  3U61 F;  3I2M X;  5E0U A;  3A1J C;  1IZ5 A;  1GE8 A;  1B8H A;  4HK1 A;  3AIX A;  4ZTD A;  2HII A;  4TR6 A;  2IX2 B;  2AVT A;  3A1J A;  3G65 C;  2ZVL A;  1UL1 A;  3A2F B;  3VKX A;  2AWA A;  3V61 B;  3G65 A;  1VYM A;  2HIK B;  3HI8 A;  2NTI B;  1RXM A;  2ZVM A;  4YHR A;  3V60 B;  3LX1 A;  5A6D A;  3GGR A;  2OD8 A;  4RJF A;  4D2G A;  1RXZ A;  3U60 F;  2IJX A;  1UD9 A;  5B7O A;  3AIX B;  2HII B;  5HAC A;  5CFK A;  5AUJ A;  3IFV A;  3A1J B;  3F1W A;  3FDS C;  1DML A;  3GPN A;  2IO4 A;  2IZO C;  3V62 B;  4L6P A;  4L60 A;  1W60 A;  5IY4 A;  1PLQ A;  3K4X A;  2ZVK A;  1T6L A; 
#chains in the Genus database with same CATH topology
 3G65 B;  1U7B A;  3P83 A;  3LX2 A;  1YYP A;  1B77 A;  1IZ4 A;  5E0T A;  3AIZ C;  2Z0L A;  3P87 A;  1SXJ F;  3U5Z F;  3GGR B;  5E0V A;  4CS5 A;  3P91 A;  5IXA A;  3WGW A;  1VYJ A;  3TBL A;  2IX2 C;  3FDS D;  5DA7 A;  2HII C;  3GPM A;  5IWD A;  1CZD A;  2IX2 A;  2IO4 B;  5H0T A;  3HSL X;  1ISQ A;  2HIK C;  2NTI C;  2IZO B;  1RWZ A;  2ZVW A;  2HIK A;  5DAI A;  2NTI A;  5JNE D;  1AXC A;  3AIZ A;  1U76 A;  3GGR C;  1PLR A;  2ZVV A;  3U61 F;  3I2M X;  5E0U A;  3A1J C;  1IZ5 A;  1GE8 A;  1B8H A;  4HK1 A;  3AIX A;  4ZTD A;  2HII A;  4TR6 A;  2IX2 B;  2AVT A;  3A1J A;  3G65 C;  2ZVL A;  1UL1 A;  3A2F B;  3VKX A;  2AWA A;  3V61 B;  3G65 A;  1VYM A;  2HIK B;  3HI8 A;  2NTI B;  1RXM A;  2ZVM A;  4YHR A;  3V60 B;  3LX1 A;  5A6D A;  3GGR A;  2OD8 A;  4RJF A;  4D2G A;  1RXZ A;  3U60 F;  2IJX A;  1UD9 A;  5B7O A;  3AIX B;  2HII B;  5HAC A;  5CFK A;  5AUJ A;  3IFV A;  3A1J B;  3F1W A;  3FDS C;  1DML A;  3GPN A;  2IO4 A;  2IZO C;  3V62 B;  4L6P A;  4L60 A;  1W60 A;  5IY4 A;  1PLQ A;  3K4X A;  2ZVK A;  1T6L A; 
#chains in the Genus database with same CATH homology
 3G65 B;  1U7B A;  3P83 A;  3LX2 A;  1YYP A;  1B77 A;  1IZ4 A;  5E0T A;  3AIZ C;  2Z0L A;  3P87 A;  1SXJ F;  3U5Z F;  3GGR B;  5E0V A;  4CS5 A;  3P91 A;  5IXA A;  3WGW A;  1VYJ A;  3TBL A;  2IX2 C;  3FDS D;  5DA7 A;  2HII C;  3GPM A;  5IWD A;  1CZD A;  2IX2 A;  2IO4 B;  5H0T A;  3HSL X;  1ISQ A;  2HIK C;  2NTI C;  2IZO B;  1RWZ A;  2ZVW A;  2HIK A;  5DAI A;  2NTI A;  5JNE D;  1AXC A;  3AIZ A;  1U76 A;  3GGR C;  1PLR A;  2ZVV A;  3U61 F;  3I2M X;  5E0U A;  3A1J C;  1IZ5 A;  1GE8 A;  1B8H A;  4HK1 A;  3AIX A;  4ZTD A;  2HII A;  4TR6 A;  2IX2 B;  2AVT A;  3A1J A;  3G65 C;  2ZVL A;  1UL1 A;  3A2F B;  3VKX A;  2AWA A;  3V61 B;  3G65 A;  1VYM A;  2HIK B;  3HI8 A;  2NTI B;  1RXM A;  2ZVM A;  4YHR A;  3V60 B;  3LX1 A;  5A6D A;  3GGR A;  2OD8 A;  4RJF A;  4D2G A;  1RXZ A;  3U60 F;  2IJX A;  1UD9 A;  5B7O A;  3AIX B;  2HII B;  5HAC A;  5CFK A;  5AUJ A;  3IFV A;  3A1J B;  3F1W A;  3FDS C;  1DML A;  3GPN A;  2IO4 A;  2IZO C;  3V62 B;  4L6P A;  4L60 A;  1W60 A;  5IY4 A;  1PLQ A;  3K4X A;  2ZVK A;  1T6L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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