5HACA

Crystal structure of proliferating cell nuclear antigen from leishmania donovani at 2.95 a resolution
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
296
structure length
260
Chain Sequence
LVPRGSHMLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVSDRGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution
rcsb
molecule tags Dna binding protein
source organism Leishmania donovani
molecule keywords Proliferating cell nuclear antigen
total genus 50
structure length 260
sequence length 296
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2015-12-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5hacA00
5DA7A 5CFKA 2IJXA 4ZTDA 1B77A 2HIKA 2HIIA 5E0UA 5JNED 2IX2B 3LX2A 3A1JA 1UL1A 3P87A 5DAIA 1IZ5A 3HSLX 2IZOC 1VYJA 1T6LA 3GPNA 1U7BA 3V62B 2NTIC 3GGRC 1PLQA 2IZOB 2IX2A 3AIZC 1IZ4A 3G65C 4CS5A 4TR6A 2NTIB 3U60F 5B7OA 2Z0LA 4D2GA 2AWAA 3P91A 3G65B 5IY4A 1RXZA 1DMLA 1UD9A 2AVTA 2ZVVA 4HK1A 3V61B 2ZVWA 3LX1A 5HACA 3U5ZF 2NTIA 3GGRA 4L6PA 3A2FB 5H0TA 4L60A 2HIKC 3G65A 3I2MX 2HIIC 3WGWA 3U61F 3AIXA 3A1JC 3GGRB 3K4XA 3VKXA 1RWZA 4RJFA 1SXJF 5IWDA 1AXCA 3V60B 3FDSC 5E0VA 1PLRA 3AIXB 3FDSD 2OD8A 1W60A 2ZVMA 2ZVKA 3TBLA 3P83A 3GPMA 3HI8A 1ISQA 1YYPA 2IO4B 3AIZA 1CZDA 1RXMA 1GE8A 5E0TA 1B8HA 5AUJA 1U76A 5IXAA 2HIKB 2HIIB 1VYMA 2ZVLA 3A1JB 3IFVA 3F1WA 5A6DA 2IO4A 4YHRA 2IX2C
chains in the Genus database with same CATH superfamily
5DA7A 5CFKA 2IJXA 4ZTDA 1B77A 2HIKA 2HIIA 5E0UA 5JNED 2IX2B 3LX2A 3A1JA 1UL1A 3P87A 5DAIA 1IZ5A 3HSLX 2IZOC 1VYJA 1T6LA 3GPNA 1U7BA 3V62B 2NTIC 3GGRC 1PLQA 2IZOB 2IX2A 3AIZC 1IZ4A 3G65C 4CS5A 4TR6A 2NTIB 3U60F 5B7OA 2Z0LA 4D2GA 2AWAA 3P91A 3G65B 5IY4A 1RXZA 1DMLA 1UD9A 2AVTA 2ZVVA 4HK1A 3V61B 2ZVWA 3LX1A 5HACA 3U5ZF 2NTIA 3GGRA 4L6PA 3A2FB 5H0TA 4L60A 2HIKC 3G65A 3I2MX 2HIIC 3WGWA 3U61F 3AIXA 3A1JC 3GGRB 3K4XA 3VKXA 1RWZA 4RJFA 1SXJF 5IWDA 1AXCA 3V60B 3FDSC 5E0VA 1PLRA 3AIXB 3FDSD 2OD8A 1W60A 2ZVMA 2ZVKA 3TBLA 3P83A 3GPMA 3HI8A 1ISQA 1YYPA 2IO4B 3AIZA 1CZDA 1RXMA 1GE8A 5E0TA 1B8HA 5AUJA 1U76A 5IXAA 2HIKB 2HIIB 1VYMA 2ZVLA 3A1JB 3IFVA 3F1WA 5A6DA 2IO4A 4YHRA 2IX2C
chains in the Genus database with same CATH topology
5DA7A 5CFKA 2IJXA 4ZTDA 1B77A 2HIKA 2HIIA 5E0UA 5JNED 2IX2B 3LX2A 3A1JA 1UL1A 3P87A 5DAIA 1IZ5A 3HSLX 2IZOC 1VYJA 1T6LA 3GPNA 1U7BA 3V62B 2NTIC 3GGRC 1PLQA 2IZOB 2IX2A 3AIZC 1IZ4A 3G65C 4CS5A 4TR6A 2NTIB 3U60F 5B7OA 2Z0LA 4D2GA 2AWAA 3P91A 3G65B 5IY4A 1RXZA 1DMLA 1UD9A 2AVTA 2ZVVA 4HK1A 3V61B 2ZVWA 3LX1A 5HACA 3U5ZF 2NTIA 3GGRA 4L6PA 3A2FB 5H0TA 4L60A 2HIKC 3G65A 3I2MX 2HIIC 3WGWA 3U61F 3AIXA 3A1JC 3GGRB 3K4XA 3VKXA 1RWZA 4RJFA 1SXJF 5IWDA 1AXCA 3V60B 3FDSC 5E0VA 1PLRA 3AIXB 3FDSD 2OD8A 1W60A 2ZVMA 2ZVKA 3TBLA 3P83A 3GPMA 3HI8A 1ISQA 1YYPA 2IO4B 3AIZA 1CZDA 1RXMA 1GE8A 5E0TA 1B8HA 5AUJA 1U76A 5IXAA 2HIKB 2HIIB 1VYMA 2ZVLA 3A1JB 3IFVA 3F1WA 5A6DA 2IO4A 4YHRA 2IX2C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DA7 A;  5CFK A;  2IJX A;  4ZTD A;  1B77 A;  2HIK A;  2HII A;  5E0U A;  5JNE D;  2IX2 B;  3LX2 A;  3A1J A;  1UL1 A;  3P87 A;  5DAI A;  1IZ5 A;  3HSL X;  2IZO C;  1VYJ A;  1T6L A;  3GPN A;  1U7B A;  3V62 B;  2NTI C;  3GGR C;  1PLQ A;  2IZO B;  2IX2 A;  3AIZ C;  1IZ4 A;  3G65 C;  4CS5 A;  4TR6 A;  2NTI B;  3U60 F;  5B7O A;  2Z0L A;  4D2G A;  2AWA A;  3P91 A;  3G65 B;  5IY4 A;  1RXZ A;  1DML A;  1UD9 A;  2AVT A;  2ZVV A;  4HK1 A;  3V61 B;  2ZVW A;  3LX1 A;  5HAC A;  3U5Z F;  2NTI A;  3GGR A;  4L6P A;  3A2F B;  5H0T A;  4L60 A;  2HIK C;  3G65 A;  3I2M X;  2HII C;  3WGW A;  3U61 F;  3AIX A;  3A1J C;  3GGR B;  3K4X A;  3VKX A;  1RWZ A;  4RJF A;  1SXJ F;  5IWD A;  1AXC A;  3V60 B;  3FDS C;  5E0V A;  1PLR A;  3AIX B;  3FDS D;  2OD8 A;  1W60 A;  2ZVM A;  2ZVK A;  3TBL A;  3P83 A;  3GPM A;  3HI8 A;  1ISQ A;  1YYP A;  2IO4 B;  3AIZ A;  1CZD A;  1RXM A;  1GE8 A;  5E0T A;  1B8H A;  5AUJ A;  1U76 A;  5IXA A;  2HIK B;  2HII B;  1VYM A;  2ZVL A;  3A1J B;  3IFV A;  3F1W A;  5A6D A;  2IO4 A;  4YHR A;  2IX2 C; 
#chains in the Genus database with same CATH topology
 5DA7 A;  5CFK A;  2IJX A;  4ZTD A;  1B77 A;  2HIK A;  2HII A;  5E0U A;  5JNE D;  2IX2 B;  3LX2 A;  3A1J A;  1UL1 A;  3P87 A;  5DAI A;  1IZ5 A;  3HSL X;  2IZO C;  1VYJ A;  1T6L A;  3GPN A;  1U7B A;  3V62 B;  2NTI C;  3GGR C;  1PLQ A;  2IZO B;  2IX2 A;  3AIZ C;  1IZ4 A;  3G65 C;  4CS5 A;  4TR6 A;  2NTI B;  3U60 F;  5B7O A;  2Z0L A;  4D2G A;  2AWA A;  3P91 A;  3G65 B;  5IY4 A;  1RXZ A;  1DML A;  1UD9 A;  2AVT A;  2ZVV A;  4HK1 A;  3V61 B;  2ZVW A;  3LX1 A;  5HAC A;  3U5Z F;  2NTI A;  3GGR A;  4L6P A;  3A2F B;  5H0T A;  4L60 A;  2HIK C;  3G65 A;  3I2M X;  2HII C;  3WGW A;  3U61 F;  3AIX A;  3A1J C;  3GGR B;  3K4X A;  3VKX A;  1RWZ A;  4RJF A;  1SXJ F;  5IWD A;  1AXC A;  3V60 B;  3FDS C;  5E0V A;  1PLR A;  3AIX B;  3FDS D;  2OD8 A;  1W60 A;  2ZVM A;  2ZVK A;  3TBL A;  3P83 A;  3GPM A;  3HI8 A;  1ISQ A;  1YYP A;  2IO4 B;  3AIZ A;  1CZD A;  1RXM A;  1GE8 A;  5E0T A;  1B8H A;  5AUJ A;  1U76 A;  5IXA A;  2HIK B;  2HII B;  1VYM A;  2ZVL A;  3A1J B;  3IFV A;  3F1W A;  5A6D A;  2IO4 A;  4YHR A;  2IX2 C; 
#chains in the Genus database with same CATH homology
 5DA7 A;  5CFK A;  2IJX A;  4ZTD A;  1B77 A;  2HIK A;  2HII A;  5E0U A;  5JNE D;  2IX2 B;  3LX2 A;  3A1J A;  1UL1 A;  3P87 A;  5DAI A;  1IZ5 A;  3HSL X;  2IZO C;  1VYJ A;  1T6L A;  3GPN A;  1U7B A;  3V62 B;  2NTI C;  3GGR C;  1PLQ A;  2IZO B;  2IX2 A;  3AIZ C;  1IZ4 A;  3G65 C;  4CS5 A;  4TR6 A;  2NTI B;  3U60 F;  5B7O A;  2Z0L A;  4D2G A;  2AWA A;  3P91 A;  3G65 B;  5IY4 A;  1RXZ A;  1DML A;  1UD9 A;  2AVT A;  2ZVV A;  4HK1 A;  3V61 B;  2ZVW A;  3LX1 A;  5HAC A;  3U5Z F;  2NTI A;  3GGR A;  4L6P A;  3A2F B;  5H0T A;  4L60 A;  2HIK C;  3G65 A;  3I2M X;  2HII C;  3WGW A;  3U61 F;  3AIX A;  3A1J C;  3GGR B;  3K4X A;  3VKX A;  1RWZ A;  4RJF A;  1SXJ F;  5IWD A;  1AXC A;  3V60 B;  3FDS C;  5E0V A;  1PLR A;  3AIX B;  3FDS D;  2OD8 A;  1W60 A;  2ZVM A;  2ZVK A;  3TBL A;  3P83 A;  3GPM A;  3HI8 A;  1ISQ A;  1YYP A;  2IO4 B;  3AIZ A;  1CZD A;  1RXM A;  1GE8 A;  5E0T A;  1B8H A;  5AUJ A;  1U76 A;  5IXA A;  2HIK B;  2HII B;  1VYM A;  2ZVL A;  3A1J B;  3IFV A;  3F1W A;  5A6D A;  2IO4 A;  4YHR A;  2IX2 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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