5IWDA

Hcmv dna polymerase subunit ul44 complex with a small molecule
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
274
structure length
261
Chain Sequence
RKDRLSEPPTLALRLKPYKTAIQQLRSVIRALKENTTVTFLPTPSLILQTVRSHCVSKITFNSSCLYITDKSFQPKTINNSTPLLGNFMYLTSSKDLTKFYVQDISDLSAKISMCAPDFNMEFSSACVHGQDIVRESENSAVHVDLDFGVVADLLKWIGPPTGTVQILVHAGPPAIKFILTNGSELEFTSNNRVSFHGVKNMRINVQLKNFYQTLLNCAVTKLPCTLRIVTEHDTLLYVASRNGLFAVENFLTEEPFQRGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
pubmed doi rcsb
molecule tags Replication/replication inhibitor
source organism Human cytomegalovirus (strain ad169)
molecule keywords DNA polymerase processivity factor
total genus 65
structure length 261
sequence length 274
ec nomenclature
pdb deposition date 2016-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03325 Herpes_PAP Herpesvirus polymerase accessory protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5iwdA00
3GPNA 1AXCA 3P83A 5CFKA 2NTIC 3FDSC 1SXJF 1IZ5A 3GPMA 3LX1A 3A1JA 1GE8A 4L6PA 2HIKC 2ZVVA 4D2GA 3P87A 3TBLA 2HIKA 1PLRA 2NTIB 2IX2C 4YHRA 1IZ4A 2AVTA 2HIIC 5A6DA 3V61B 4ZTDA 3K4XA 2HIKB 3F1WA 3WGWA 3A2FB 1W60A 5IWDA 3G65B 3AIZC 2ZVLA 2NTIA 2IX2B 5IY4A 4RJFA 3V62B 3HSLX 1U7BA 5H0TA 2HIIB 3GGRC 2IJXA 5E0UA 4CS5A 3AIXB 3G65C 5JNED 3G65A 1DMLA 1B77A 2IX2A 1PLQA 3V60B 2ZVKA 1YYPA 3U5ZF 1VYJA 3IFVA 2HIIA 3GGRB 3VKXA 1UL1A 2IO4B 1ISQA 1VYMA 1B8HA 3LX2A 3AIXA 5HACA 2ZVMA 3P91A 1T6LA 3AIZA 3U60F 4L60A 1CZDA 3GGRA 2IO4A 5B7OA 2IZOC 5DAIA 3U61F 3I2MX 5E0VA 2ZVWA 4TR6A 1RXMA 3A1JC 1RWZA 5AUJA 2AWAA 1U76A 2IZOB 5DA7A 3FDSD 1UD9A 2Z0LA 3HI8A 3A1JB 4HK1A 2OD8A 5E0TA 5IXAA 1RXZA
chains in the Genus database with same CATH superfamily
3GPNA 1AXCA 3P83A 5CFKA 2NTIC 3FDSC 1SXJF 1IZ5A 3GPMA 3LX1A 3A1JA 1GE8A 4L6PA 2HIKC 2ZVVA 4D2GA 3P87A 3TBLA 2HIKA 1PLRA 2NTIB 2IX2C 4YHRA 1IZ4A 2AVTA 2HIIC 5A6DA 3V61B 4ZTDA 3K4XA 2HIKB 3F1WA 3WGWA 3A2FB 1W60A 5IWDA 3G65B 3AIZC 2ZVLA 2NTIA 2IX2B 5IY4A 4RJFA 3V62B 3HSLX 1U7BA 5H0TA 2HIIB 3GGRC 2IJXA 5E0UA 4CS5A 3AIXB 3G65C 5JNED 3G65A 1DMLA 1B77A 2IX2A 1PLQA 3V60B 2ZVKA 1YYPA 3U5ZF 1VYJA 3IFVA 2HIIA 3GGRB 3VKXA 1UL1A 2IO4B 1ISQA 1VYMA 1B8HA 3LX2A 3AIXA 5HACA 2ZVMA 3P91A 1T6LA 3AIZA 3U60F 4L60A 1CZDA 3GGRA 2IO4A 5B7OA 2IZOC 5DAIA 3U61F 3I2MX 5E0VA 2ZVWA 4TR6A 1RXMA 3A1JC 1RWZA 5AUJA 2AWAA 1U76A 2IZOB 5DA7A 3FDSD 1UD9A 2Z0LA 3HI8A 3A1JB 4HK1A 2OD8A 5E0TA 5IXAA 1RXZA
chains in the Genus database with same CATH topology
3GPNA 1AXCA 3P83A 5CFKA 2NTIC 3FDSC 1SXJF 1IZ5A 3GPMA 3LX1A 3A1JA 1GE8A 4L6PA 2HIKC 2ZVVA 4D2GA 3P87A 3TBLA 2HIKA 1PLRA 2NTIB 2IX2C 4YHRA 1IZ4A 2AVTA 2HIIC 5A6DA 3V61B 4ZTDA 3K4XA 2HIKB 3F1WA 3WGWA 3A2FB 1W60A 5IWDA 3G65B 3AIZC 2ZVLA 2NTIA 2IX2B 5IY4A 4RJFA 3V62B 3HSLX 1U7BA 5H0TA 2HIIB 3GGRC 2IJXA 5E0UA 4CS5A 3AIXB 3G65C 5JNED 3G65A 1DMLA 1B77A 2IX2A 1PLQA 3V60B 2ZVKA 1YYPA 3U5ZF 1VYJA 3IFVA 2HIIA 3GGRB 3VKXA 1UL1A 2IO4B 1ISQA 1VYMA 1B8HA 3LX2A 3AIXA 5HACA 2ZVMA 3P91A 1T6LA 3AIZA 3U60F 4L60A 1CZDA 3GGRA 2IO4A 5B7OA 2IZOC 5DAIA 3U61F 3I2MX 5E0VA 2ZVWA 4TR6A 1RXMA 3A1JC 1RWZA 5AUJA 2AWAA 1U76A 2IZOB 5DA7A 3FDSD 1UD9A 2Z0LA 3HI8A 3A1JB 4HK1A 2OD8A 5E0TA 5IXAA 1RXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GPN A;  1AXC A;  3P83 A;  5CFK A;  2NTI C;  3FDS C;  1SXJ F;  1IZ5 A;  3GPM A;  3LX1 A;  3A1J A;  1GE8 A;  4L6P A;  2HIK C;  2ZVV A;  4D2G A;  3P87 A;  3TBL A;  2HIK A;  1PLR A;  2NTI B;  2IX2 C;  4YHR A;  1IZ4 A;  2AVT A;  2HII C;  5A6D A;  3V61 B;  4ZTD A;  3K4X A;  2HIK B;  3F1W A;  3WGW A;  3A2F B;  1W60 A;  5IWD A;  3G65 B;  3AIZ C;  2ZVL A;  2NTI A;  2IX2 B;  5IY4 A;  4RJF A;  3V62 B;  3HSL X;  1U7B A;  5H0T A;  2HII B;  3GGR C;  2IJX A;  5E0U A;  4CS5 A;  3AIX B;  3G65 C;  5JNE D;  3G65 A;  1DML A;  1B77 A;  2IX2 A;  1PLQ A;  3V60 B;  2ZVK A;  1YYP A;  3U5Z F;  1VYJ A;  3IFV A;  2HII A;  3GGR B;  3VKX A;  1UL1 A;  2IO4 B;  1ISQ A;  1VYM A;  1B8H A;  3LX2 A;  3AIX A;  5HAC A;  2ZVM A;  3P91 A;  1T6L A;  3AIZ A;  3U60 F;  4L60 A;  1CZD A;  3GGR A;  2IO4 A;  5B7O A;  2IZO C;  5DAI A;  3U61 F;  3I2M X;  5E0V A;  2ZVW A;  4TR6 A;  1RXM A;  3A1J C;  1RWZ A;  5AUJ A;  2AWA A;  1U76 A;  2IZO B;  5DA7 A;  3FDS D;  1UD9 A;  2Z0L A;  3HI8 A;  3A1J B;  4HK1 A;  2OD8 A;  5E0T A;  5IXA A;  1RXZ A; 
#chains in the Genus database with same CATH topology
 3GPN A;  1AXC A;  3P83 A;  5CFK A;  2NTI C;  3FDS C;  1SXJ F;  1IZ5 A;  3GPM A;  3LX1 A;  3A1J A;  1GE8 A;  4L6P A;  2HIK C;  2ZVV A;  4D2G A;  3P87 A;  3TBL A;  2HIK A;  1PLR A;  2NTI B;  2IX2 C;  4YHR A;  1IZ4 A;  2AVT A;  2HII C;  5A6D A;  3V61 B;  4ZTD A;  3K4X A;  2HIK B;  3F1W A;  3WGW A;  3A2F B;  1W60 A;  5IWD A;  3G65 B;  3AIZ C;  2ZVL A;  2NTI A;  2IX2 B;  5IY4 A;  4RJF A;  3V62 B;  3HSL X;  1U7B A;  5H0T A;  2HII B;  3GGR C;  2IJX A;  5E0U A;  4CS5 A;  3AIX B;  3G65 C;  5JNE D;  3G65 A;  1DML A;  1B77 A;  2IX2 A;  1PLQ A;  3V60 B;  2ZVK A;  1YYP A;  3U5Z F;  1VYJ A;  3IFV A;  2HII A;  3GGR B;  3VKX A;  1UL1 A;  2IO4 B;  1ISQ A;  1VYM A;  1B8H A;  3LX2 A;  3AIX A;  5HAC A;  2ZVM A;  3P91 A;  1T6L A;  3AIZ A;  3U60 F;  4L60 A;  1CZD A;  3GGR A;  2IO4 A;  5B7O A;  2IZO C;  5DAI A;  3U61 F;  3I2M X;  5E0V A;  2ZVW A;  4TR6 A;  1RXM A;  3A1J C;  1RWZ A;  5AUJ A;  2AWA A;  1U76 A;  2IZO B;  5DA7 A;  3FDS D;  1UD9 A;  2Z0L A;  3HI8 A;  3A1J B;  4HK1 A;  2OD8 A;  5E0T A;  5IXA A;  1RXZ A; 
#chains in the Genus database with same CATH homology
 3GPN A;  1AXC A;  3P83 A;  5CFK A;  2NTI C;  3FDS C;  1SXJ F;  1IZ5 A;  3GPM A;  3LX1 A;  3A1J A;  1GE8 A;  4L6P A;  2HIK C;  2ZVV A;  4D2G A;  3P87 A;  3TBL A;  2HIK A;  1PLR A;  2NTI B;  2IX2 C;  4YHR A;  1IZ4 A;  2AVT A;  2HII C;  5A6D A;  3V61 B;  4ZTD A;  3K4X A;  2HIK B;  3F1W A;  3WGW A;  3A2F B;  1W60 A;  5IWD A;  3G65 B;  3AIZ C;  2ZVL A;  2NTI A;  2IX2 B;  5IY4 A;  4RJF A;  3V62 B;  3HSL X;  1U7B A;  5H0T A;  2HII B;  3GGR C;  2IJX A;  5E0U A;  4CS5 A;  3AIX B;  3G65 C;  5JNE D;  3G65 A;  1DML A;  1B77 A;  2IX2 A;  1PLQ A;  3V60 B;  2ZVK A;  1YYP A;  3U5Z F;  1VYJ A;  3IFV A;  2HII A;  3GGR B;  3VKX A;  1UL1 A;  2IO4 B;  1ISQ A;  1VYM A;  1B8H A;  3LX2 A;  3AIX A;  5HAC A;  2ZVM A;  3P91 A;  1T6L A;  3AIZ A;  3U60 F;  4L60 A;  1CZD A;  3GGR A;  2IO4 A;  5B7O A;  2IZO C;  5DAI A;  3U61 F;  3I2M X;  5E0V A;  2ZVW A;  4TR6 A;  1RXM A;  3A1J C;  1RWZ A;  5AUJ A;  2AWA A;  1U76 A;  2IZO B;  5DA7 A;  3FDS D;  1UD9 A;  2Z0L A;  3HI8 A;  3A1J B;  4HK1 A;  2OD8 A;  5E0T A;  5IXA A;  1RXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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