5H0TA

Crystal structure of proliferating cell nuclear antigen from leishmania donovani at 2.73 angstrom resolution
Total Genus 56
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
289
structure length
248
Chain Sequence
MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Leishmania donovani
molecule keywords Proliferating cell nuclear antigen
total genus 56
structure length 248
sequence length 289
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2016-10-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
A PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5h0tA00
2NTIA 2ZVKA 3IFVA 3A1JC 5HACA 3G65A 2HIIB 2IZOC 1W60A 2Z0LA 3K4XA 1DMLA 2NTIB 2IX2B 3G65B 5IXAA 3U60F 2IO4A 2HIIC 5E0VA 1RXZA 3TBLA 3U61F 1B8HA 3P87A 3GGRA 3V62B 2IX2C 2ZVLA 1IZ5A 2IO4B 2HIKA 3AIXA 4L6PA 4D2GA 3GGRB 3GPMA 3LX1A 5B7OA 3VKXA 1AXCA 2AWAA 3GGRC 4TR6A 1IZ4A 1U7BA 5JNED 4ZTDA 5E0UA 3HI8A 3GPNA 2IJXA 2NTIC 5DAIA 3G65C 4L60A 2ZVWA 1UL1A 5E0TA 3AIZA 4CS5A 1ISQA 1SXJF 1CZDA 2HIKB 3A1JA 3AIXB 5IY4A 5A6DA 3LX2A 4RJFA 3F1WA 5IWDA 3A2FB 1T6LA 3A1JB 3WGWA 1U76A 3V61B 5AUJA 3FDSD 2HIKC 3FDSC 1PLQA 3P83A 3AIZC 1VYJA 4YHRA 1YYPA 2OD8A 2IX2A 2ZVVA 2AVTA 1RWZA 1RXMA 1B77A 1VYMA 1GE8A 1UD9A 3V60B 3U5ZF 3I2MX 5DA7A 2ZVMA 5H0TA 3HSLX 3P91A 2HIIA 2IZOB 4HK1A 5CFKA 1PLRA
chains in the Genus database with same CATH superfamily
2NTIA 2ZVKA 3IFVA 3A1JC 5HACA 3G65A 2HIIB 2IZOC 1W60A 2Z0LA 3K4XA 1DMLA 2NTIB 2IX2B 3G65B 5IXAA 3U60F 2IO4A 2HIIC 5E0VA 1RXZA 3TBLA 3U61F 1B8HA 3P87A 3GGRA 3V62B 2IX2C 2ZVLA 1IZ5A 2IO4B 2HIKA 3AIXA 4L6PA 4D2GA 3GGRB 3GPMA 3LX1A 5B7OA 3VKXA 1AXCA 2AWAA 3GGRC 4TR6A 1IZ4A 1U7BA 5JNED 4ZTDA 5E0UA 3HI8A 3GPNA 2IJXA 2NTIC 5DAIA 3G65C 4L60A 2ZVWA 1UL1A 5E0TA 3AIZA 4CS5A 1ISQA 1SXJF 1CZDA 2HIKB 3A1JA 3AIXB 5IY4A 5A6DA 3LX2A 4RJFA 3F1WA 5IWDA 3A2FB 1T6LA 3A1JB 3WGWA 1U76A 3V61B 5AUJA 3FDSD 2HIKC 3FDSC 1PLQA 3P83A 3AIZC 1VYJA 4YHRA 1YYPA 2OD8A 2IX2A 2ZVVA 2AVTA 1RWZA 1RXMA 1B77A 1VYMA 1GE8A 1UD9A 3V60B 3U5ZF 3I2MX 5DA7A 2ZVMA 5H0TA 3HSLX 3P91A 2HIIA 2IZOB 4HK1A 5CFKA 1PLRA
chains in the Genus database with same CATH topology
2NTIA 2ZVKA 3IFVA 3A1JC 5HACA 3G65A 2HIIB 2IZOC 1W60A 2Z0LA 3K4XA 1DMLA 2NTIB 2IX2B 3G65B 5IXAA 3U60F 2IO4A 2HIIC 5E0VA 1RXZA 3TBLA 3U61F 1B8HA 3P87A 3GGRA 3V62B 2IX2C 2ZVLA 1IZ5A 2IO4B 2HIKA 3AIXA 4L6PA 4D2GA 3GGRB 3GPMA 3LX1A 5B7OA 3VKXA 1AXCA 2AWAA 3GGRC 4TR6A 1IZ4A 1U7BA 5JNED 4ZTDA 5E0UA 3HI8A 3GPNA 2IJXA 2NTIC 5DAIA 3G65C 4L60A 2ZVWA 1UL1A 5E0TA 3AIZA 4CS5A 1ISQA 1SXJF 1CZDA 2HIKB 3A1JA 3AIXB 5IY4A 5A6DA 3LX2A 4RJFA 3F1WA 5IWDA 3A2FB 1T6LA 3A1JB 3WGWA 1U76A 3V61B 5AUJA 3FDSD 2HIKC 3FDSC 1PLQA 3P83A 3AIZC 1VYJA 4YHRA 1YYPA 2OD8A 2IX2A 2ZVVA 2AVTA 1RWZA 1RXMA 1B77A 1VYMA 1GE8A 1UD9A 3V60B 3U5ZF 3I2MX 5DA7A 2ZVMA 5H0TA 3HSLX 3P91A 2HIIA 2IZOB 4HK1A 5CFKA 1PLRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NTI A;  2ZVK A;  3IFV A;  3A1J C;  5HAC A;  3G65 A;  2HII B;  2IZO C;  1W60 A;  2Z0L A;  3K4X A;  1DML A;  2NTI B;  2IX2 B;  3G65 B;  5IXA A;  3U60 F;  2IO4 A;  2HII C;  5E0V A;  1RXZ A;  3TBL A;  3U61 F;  1B8H A;  3P87 A;  3GGR A;  3V62 B;  2IX2 C;  2ZVL A;  1IZ5 A;  2IO4 B;  2HIK A;  3AIX A;  4L6P A;  4D2G A;  3GGR B;  3GPM A;  3LX1 A;  5B7O A;  3VKX A;  1AXC A;  2AWA A;  3GGR C;  4TR6 A;  1IZ4 A;  1U7B A;  5JNE D;  4ZTD A;  5E0U A;  3HI8 A;  3GPN A;  2IJX A;  2NTI C;  5DAI A;  3G65 C;  4L60 A;  2ZVW A;  1UL1 A;  5E0T A;  3AIZ A;  4CS5 A;  1ISQ A;  1SXJ F;  1CZD A;  2HIK B;  3A1J A;  3AIX B;  5IY4 A;  5A6D A;  3LX2 A;  4RJF A;  3F1W A;  5IWD A;  3A2F B;  1T6L A;  3A1J B;  3WGW A;  1U76 A;  3V61 B;  5AUJ A;  3FDS D;  2HIK C;  3FDS C;  1PLQ A;  3P83 A;  3AIZ C;  1VYJ A;  4YHR A;  1YYP A;  2OD8 A;  2IX2 A;  2ZVV A;  2AVT A;  1RWZ A;  1RXM A;  1B77 A;  1VYM A;  1GE8 A;  1UD9 A;  3V60 B;  3U5Z F;  3I2M X;  5DA7 A;  2ZVM A;  5H0T A;  3HSL X;  3P91 A;  2HII A;  2IZO B;  4HK1 A;  5CFK A;  1PLR A; 
#chains in the Genus database with same CATH topology
 2NTI A;  2ZVK A;  3IFV A;  3A1J C;  5HAC A;  3G65 A;  2HII B;  2IZO C;  1W60 A;  2Z0L A;  3K4X A;  1DML A;  2NTI B;  2IX2 B;  3G65 B;  5IXA A;  3U60 F;  2IO4 A;  2HII C;  5E0V A;  1RXZ A;  3TBL A;  3U61 F;  1B8H A;  3P87 A;  3GGR A;  3V62 B;  2IX2 C;  2ZVL A;  1IZ5 A;  2IO4 B;  2HIK A;  3AIX A;  4L6P A;  4D2G A;  3GGR B;  3GPM A;  3LX1 A;  5B7O A;  3VKX A;  1AXC A;  2AWA A;  3GGR C;  4TR6 A;  1IZ4 A;  1U7B A;  5JNE D;  4ZTD A;  5E0U A;  3HI8 A;  3GPN A;  2IJX A;  2NTI C;  5DAI A;  3G65 C;  4L60 A;  2ZVW A;  1UL1 A;  5E0T A;  3AIZ A;  4CS5 A;  1ISQ A;  1SXJ F;  1CZD A;  2HIK B;  3A1J A;  3AIX B;  5IY4 A;  5A6D A;  3LX2 A;  4RJF A;  3F1W A;  5IWD A;  3A2F B;  1T6L A;  3A1J B;  3WGW A;  1U76 A;  3V61 B;  5AUJ A;  3FDS D;  2HIK C;  3FDS C;  1PLQ A;  3P83 A;  3AIZ C;  1VYJ A;  4YHR A;  1YYP A;  2OD8 A;  2IX2 A;  2ZVV A;  2AVT A;  1RWZ A;  1RXM A;  1B77 A;  1VYM A;  1GE8 A;  1UD9 A;  3V60 B;  3U5Z F;  3I2M X;  5DA7 A;  2ZVM A;  5H0T A;  3HSL X;  3P91 A;  2HII A;  2IZO B;  4HK1 A;  5CFK A;  1PLR A; 
#chains in the Genus database with same CATH homology
 2NTI A;  2ZVK A;  3IFV A;  3A1J C;  5HAC A;  3G65 A;  2HII B;  2IZO C;  1W60 A;  2Z0L A;  3K4X A;  1DML A;  2NTI B;  2IX2 B;  3G65 B;  5IXA A;  3U60 F;  2IO4 A;  2HII C;  5E0V A;  1RXZ A;  3TBL A;  3U61 F;  1B8H A;  3P87 A;  3GGR A;  3V62 B;  2IX2 C;  2ZVL A;  1IZ5 A;  2IO4 B;  2HIK A;  3AIX A;  4L6P A;  4D2G A;  3GGR B;  3GPM A;  3LX1 A;  5B7O A;  3VKX A;  1AXC A;  2AWA A;  3GGR C;  4TR6 A;  1IZ4 A;  1U7B A;  5JNE D;  4ZTD A;  5E0U A;  3HI8 A;  3GPN A;  2IJX A;  2NTI C;  5DAI A;  3G65 C;  4L60 A;  2ZVW A;  1UL1 A;  5E0T A;  3AIZ A;  4CS5 A;  1ISQ A;  1SXJ F;  1CZD A;  2HIK B;  3A1J A;  3AIX B;  5IY4 A;  5A6D A;  3LX2 A;  4RJF A;  3F1W A;  5IWD A;  3A2F B;  1T6L A;  3A1J B;  3WGW A;  1U76 A;  3V61 B;  5AUJ A;  3FDS D;  2HIK C;  3FDS C;  1PLQ A;  3P83 A;  3AIZ C;  1VYJ A;  4YHR A;  1YYP A;  2OD8 A;  2IX2 A;  2ZVV A;  2AVT A;  1RWZ A;  1RXM A;  1B77 A;  1VYM A;  1GE8 A;  1UD9 A;  3V60 B;  3U5Z F;  3I2M X;  5DA7 A;  2ZVM A;  5H0T A;  3HSL X;  3P91 A;  2HII A;  2IZO B;  4HK1 A;  5CFK A;  1PLR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...