5IWDA

Hcmv dna polymerase subunit ul44 complex with a small molecule
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
274
structure length
261
Chain Sequence
RKDRLSEPPTLALRLKPYKTAIQQLRSVIRALKENTTVTFLPTPSLILQTVRSHCVSKITFNSSCLYITDKSFQPKTINNSTPLLGNFMYLTSSKDLTKFYVQDISDLSAKISMCAPDFNMEFSSACVHGQDIVRESENSAVHVDLDFGVVADLLKWIGPPTGTVQILVHAGPPAIKFILTNGSELEFTSNNRVSFHGVKNMRINVQLKNFYQTLLNCAVTKLPCTLRIVTEHDTLLYVASRNGLFAVENFLTEEPFQRGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
pubmed doi rcsb
molecule tags Replication/replication inhibitor
source organism Human cytomegalovirus (strain ad169)
molecule keywords DNA polymerase processivity factor
total genus 65
structure length 261
sequence length 274
ec nomenclature
pdb deposition date 2016-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03325 Herpes_PAP Herpesvirus polymerase accessory protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5iwdA00
1SXJF 1CZDA 3AIXB 2IJXA 5DA7A 2IO4A 3LX2A 5DAIA 1B77A 3WGWA 4ZTDA 3LX1A 5IWDA 1W60A 1T6LA 2IO4B 1UL1A 1B8HA 4CS5A 3K4XA 3HI8A 5AUJA 3V60B 1IZ4A 3GPMA 4RJFA 2HIIB 4YHRA 3I2MX 5HACA 3GGRA 2OD8A 2AWAA 2AVTA 1RXZA 3A1JA 2ZVWA 3IFVA 1YYPA 3GGRB 4HK1A 1UD9A 1VYJA 1RWZA 3A2FB 1IZ5A 2HIKA 5H0TA 2HIIA 3GGRC 5IY4A 3A1JB 2ZVMA 3HSLX 2ZVVA 1U7BA 3V62B 1VYMA 3V61B 2HIKB 3A1JC 5B7OA 4TR6A 3FDSC 3VKXA 2IZOB 2ZVKA 1AXCA 2HIKC 2HIIC 3AIZA 2IZOC 5A6DA 3P87A 3G65B 2NTIB 3F1WA 1PLRA 3P83A 1ISQA 3FDSD 4L6PA 2Z0LA 3P91A 5E0VA 1U76A 3U61F 3U60F 2IX2A 3TBLA 5JNED 3U5ZF 1PLQA 2ZVLA 4L60A 5CFKA 5E0UA 3GPNA 5E0TA 3G65A 2IX2B 2NTIA 1DMLA 4D2GA 2IX2C 5IXAA 1RXMA 3AIXA 3G65C 2NTIC 1GE8A 3AIZC
chains in the Genus database with same CATH superfamily
1SXJF 1CZDA 3AIXB 2IJXA 5DA7A 2IO4A 3LX2A 5DAIA 1B77A 3WGWA 4ZTDA 3LX1A 5IWDA 1W60A 1T6LA 2IO4B 1UL1A 1B8HA 4CS5A 3K4XA 3HI8A 5AUJA 3V60B 1IZ4A 3GPMA 4RJFA 2HIIB 4YHRA 3I2MX 5HACA 3GGRA 2OD8A 2AWAA 2AVTA 1RXZA 3A1JA 2ZVWA 3IFVA 1YYPA 3GGRB 4HK1A 1UD9A 1VYJA 1RWZA 3A2FB 1IZ5A 2HIKA 5H0TA 2HIIA 3GGRC 5IY4A 3A1JB 2ZVMA 3HSLX 2ZVVA 1U7BA 3V62B 1VYMA 3V61B 2HIKB 3A1JC 5B7OA 4TR6A 3FDSC 3VKXA 2IZOB 2ZVKA 1AXCA 2HIKC 2HIIC 3AIZA 2IZOC 5A6DA 3P87A 3G65B 2NTIB 3F1WA 1PLRA 3P83A 1ISQA 3FDSD 4L6PA 2Z0LA 3P91A 5E0VA 1U76A 3U61F 3U60F 2IX2A 3TBLA 5JNED 3U5ZF 1PLQA 2ZVLA 4L60A 5CFKA 5E0UA 3GPNA 5E0TA 3G65A 2IX2B 2NTIA 1DMLA 4D2GA 2IX2C 5IXAA 1RXMA 3AIXA 3G65C 2NTIC 1GE8A 3AIZC
chains in the Genus database with same CATH topology
1SXJF 1CZDA 3AIXB 2IJXA 5DA7A 2IO4A 3LX2A 5DAIA 1B77A 3WGWA 4ZTDA 3LX1A 5IWDA 1W60A 1T6LA 2IO4B 1UL1A 1B8HA 4CS5A 3K4XA 3HI8A 5AUJA 3V60B 1IZ4A 3GPMA 4RJFA 2HIIB 4YHRA 3I2MX 5HACA 3GGRA 2OD8A 2AWAA 2AVTA 1RXZA 3A1JA 2ZVWA 3IFVA 1YYPA 3GGRB 4HK1A 1UD9A 1VYJA 1RWZA 3A2FB 1IZ5A 2HIKA 5H0TA 2HIIA 3GGRC 5IY4A 3A1JB 2ZVMA 3HSLX 2ZVVA 1U7BA 3V62B 1VYMA 3V61B 2HIKB 3A1JC 5B7OA 4TR6A 3FDSC 3VKXA 2IZOB 2ZVKA 1AXCA 2HIKC 2HIIC 3AIZA 2IZOC 5A6DA 3P87A 3G65B 2NTIB 3F1WA 1PLRA 3P83A 1ISQA 3FDSD 4L6PA 2Z0LA 3P91A 5E0VA 1U76A 3U61F 3U60F 2IX2A 3TBLA 5JNED 3U5ZF 1PLQA 2ZVLA 4L60A 5CFKA 5E0UA 3GPNA 5E0TA 3G65A 2IX2B 2NTIA 1DMLA 4D2GA 2IX2C 5IXAA 1RXMA 3AIXA 3G65C 2NTIC 1GE8A 3AIZC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SXJ F;  1CZD A;  3AIX B;  2IJX A;  5DA7 A;  2IO4 A;  3LX2 A;  5DAI A;  1B77 A;  3WGW A;  4ZTD A;  3LX1 A;  5IWD A;  1W60 A;  1T6L A;  2IO4 B;  1UL1 A;  1B8H A;  4CS5 A;  3K4X A;  3HI8 A;  5AUJ A;  3V60 B;  1IZ4 A;  3GPM A;  4RJF A;  2HII B;  4YHR A;  3I2M X;  5HAC A;  3GGR A;  2OD8 A;  2AWA A;  2AVT A;  1RXZ A;  3A1J A;  2ZVW A;  3IFV A;  1YYP A;  3GGR B;  4HK1 A;  1UD9 A;  1VYJ A;  1RWZ A;  3A2F B;  1IZ5 A;  2HIK A;  5H0T A;  2HII A;  3GGR C;  5IY4 A;  3A1J B;  2ZVM A;  3HSL X;  2ZVV A;  1U7B A;  3V62 B;  1VYM A;  3V61 B;  2HIK B;  3A1J C;  5B7O A;  4TR6 A;  3FDS C;  3VKX A;  2IZO B;  2ZVK A;  1AXC A;  2HIK C;  2HII C;  3AIZ A;  2IZO C;  5A6D A;  3P87 A;  3G65 B;  2NTI B;  3F1W A;  1PLR A;  3P83 A;  1ISQ A;  3FDS D;  4L6P A;  2Z0L A;  3P91 A;  5E0V A;  1U76 A;  3U61 F;  3U60 F;  2IX2 A;  3TBL A;  5JNE D;  3U5Z F;  1PLQ A;  2ZVL A;  4L60 A;  5CFK A;  5E0U A;  3GPN A;  5E0T A;  3G65 A;  2IX2 B;  2NTI A;  1DML A;  4D2G A;  2IX2 C;  5IXA A;  1RXM A;  3AIX A;  3G65 C;  2NTI C;  1GE8 A;  3AIZ C; 
#chains in the Genus database with same CATH topology
 1SXJ F;  1CZD A;  3AIX B;  2IJX A;  5DA7 A;  2IO4 A;  3LX2 A;  5DAI A;  1B77 A;  3WGW A;  4ZTD A;  3LX1 A;  5IWD A;  1W60 A;  1T6L A;  2IO4 B;  1UL1 A;  1B8H A;  4CS5 A;  3K4X A;  3HI8 A;  5AUJ A;  3V60 B;  1IZ4 A;  3GPM A;  4RJF A;  2HII B;  4YHR A;  3I2M X;  5HAC A;  3GGR A;  2OD8 A;  2AWA A;  2AVT A;  1RXZ A;  3A1J A;  2ZVW A;  3IFV A;  1YYP A;  3GGR B;  4HK1 A;  1UD9 A;  1VYJ A;  1RWZ A;  3A2F B;  1IZ5 A;  2HIK A;  5H0T A;  2HII A;  3GGR C;  5IY4 A;  3A1J B;  2ZVM A;  3HSL X;  2ZVV A;  1U7B A;  3V62 B;  1VYM A;  3V61 B;  2HIK B;  3A1J C;  5B7O A;  4TR6 A;  3FDS C;  3VKX A;  2IZO B;  2ZVK A;  1AXC A;  2HIK C;  2HII C;  3AIZ A;  2IZO C;  5A6D A;  3P87 A;  3G65 B;  2NTI B;  3F1W A;  1PLR A;  3P83 A;  1ISQ A;  3FDS D;  4L6P A;  2Z0L A;  3P91 A;  5E0V A;  1U76 A;  3U61 F;  3U60 F;  2IX2 A;  3TBL A;  5JNE D;  3U5Z F;  1PLQ A;  2ZVL A;  4L60 A;  5CFK A;  5E0U A;  3GPN A;  5E0T A;  3G65 A;  2IX2 B;  2NTI A;  1DML A;  4D2G A;  2IX2 C;  5IXA A;  1RXM A;  3AIX A;  3G65 C;  2NTI C;  1GE8 A;  3AIZ C; 
#chains in the Genus database with same CATH homology
 1SXJ F;  1CZD A;  3AIX B;  2IJX A;  5DA7 A;  2IO4 A;  3LX2 A;  5DAI A;  1B77 A;  3WGW A;  4ZTD A;  3LX1 A;  5IWD A;  1W60 A;  1T6L A;  2IO4 B;  1UL1 A;  1B8H A;  4CS5 A;  3K4X A;  3HI8 A;  5AUJ A;  3V60 B;  1IZ4 A;  3GPM A;  4RJF A;  2HII B;  4YHR A;  3I2M X;  5HAC A;  3GGR A;  2OD8 A;  2AWA A;  2AVT A;  1RXZ A;  3A1J A;  2ZVW A;  3IFV A;  1YYP A;  3GGR B;  4HK1 A;  1UD9 A;  1VYJ A;  1RWZ A;  3A2F B;  1IZ5 A;  2HIK A;  5H0T A;  2HII A;  3GGR C;  5IY4 A;  3A1J B;  2ZVM A;  3HSL X;  2ZVV A;  1U7B A;  3V62 B;  1VYM A;  3V61 B;  2HIK B;  3A1J C;  5B7O A;  4TR6 A;  3FDS C;  3VKX A;  2IZO B;  2ZVK A;  1AXC A;  2HIK C;  2HII C;  3AIZ A;  2IZO C;  5A6D A;  3P87 A;  3G65 B;  2NTI B;  3F1W A;  1PLR A;  3P83 A;  1ISQ A;  3FDS D;  4L6P A;  2Z0L A;  3P91 A;  5E0V A;  1U76 A;  3U61 F;  3U60 F;  2IX2 A;  3TBL A;  5JNE D;  3U5Z F;  1PLQ A;  2ZVL A;  4L60 A;  5CFK A;  5E0U A;  3GPN A;  5E0T A;  3G65 A;  2IX2 B;  2NTI A;  1DML A;  4D2G A;  2IX2 C;  5IXA A;  1RXM A;  3AIX A;  3G65 C;  2NTI C;  1GE8 A;  3AIZ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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