5IWDA

Hcmv dna polymerase subunit ul44 complex with a small molecule
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
274
structure length
261
Chain Sequence
RKDRLSEPPTLALRLKPYKTAIQQLRSVIRALKENTTVTFLPTPSLILQTVRSHCVSKITFNSSCLYITDKSFQPKTINNSTPLLGNFMYLTSSKDLTKFYVQDISDLSAKISMCAPDFNMEFSSACVHGQDIVRESENSAVHVDLDFGVVADLLKWIGPPTGTVQILVHAGPPAIKFILTNGSELEFTSNNRVSFHGVKNMRINVQLKNFYQTLLNCAVTKLPCTLRIVTEHDTLLYVASRNGLFAVENFLTEEPFQRGD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Replication/replication inhibitor
molecule keywords DNA polymerase processivity factor
publication title A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
pubmed doi rcsb
source organism Human cytomegalovirus (strain ad169)
total genus 65
structure length 261
sequence length 274
ec nomenclature
pdb deposition date 2016-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03325 Herpes_PAP Herpesvirus polymerase accessory protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 5iwdA00
3G65A 4L60A 3G65C 4L6PA 3FDSD 4ZTDA 1U76A 4D2GA 3HI8A 3U5ZF 3V61B 2IZOB 1B77A 3G65B 1AXCA 3U61F 5CFKA 2ZVMA 3GGRA 2Z0LA 1IZ4A 3I2MX 1U7BA 2NTIB 5AUJA 1B8HA 2IJXA 5DAIA 1YYPA 2AVTA 3GPMA 3FDSC 2IZOC 3GGRB 2HIIB 3HSLX 1VYMA 1UD9A 3LX2A 2ZVKA 1ISQA 2ZVLA 3LX1A 4TR6A 5E0UA 2AWAA 2NTIA 3WGWA 3V60B 2HIKA 1PLQA 2NTIC 3F1WA 3K4XA 2HIIA 3GGRC 2HIIC 3TBLA 3A2FB 5E0VA 2IX2A 2IX2C 4YHRA 2HIKB 1W60A 3P87A 5A6DA 1RXZA 5H0TA 1UL1A 1PLRA 2IO4A 2IX2B 5HACA 1DMLA 2HIKC 1IZ5A 4RJFA 2IO4B 5DA7A 5E0TA 3A1JA 2ZVWA 3A1JC 5IY4A 3V62B 3AIXA 3IFVA 3P83A 3VKXA 3AIZA 5B7OA 1RXMA 3AIZC 5IXAA 1RWZA 2OD8A 3P91A 3A1JB 4HK1A 3AIXB 1SXJF 5JNED 4CS5A 3U60F 2ZVVA 1GE8A 1CZDA 5IWDA 1VYJA 1T6LA 3GPNA
chains in the Genus database with same CATH superfamily
3G65A 4L60A 3G65C 4L6PA 3FDSD 4ZTDA 1U76A 4D2GA 3HI8A 3U5ZF 3V61B 2IZOB 1B77A 3G65B 1AXCA 3U61F 5CFKA 2ZVMA 3GGRA 2Z0LA 1IZ4A 3I2MX 1U7BA 2NTIB 5AUJA 1B8HA 2IJXA 5DAIA 1YYPA 2AVTA 3GPMA 3FDSC 2IZOC 3GGRB 2HIIB 3HSLX 1VYMA 1UD9A 3LX2A 2ZVKA 1ISQA 2ZVLA 3LX1A 4TR6A 5E0UA 2AWAA 2NTIA 3WGWA 3V60B 2HIKA 1PLQA 2NTIC 3F1WA 3K4XA 2HIIA 3GGRC 2HIIC 3TBLA 3A2FB 5E0VA 2IX2A 2IX2C 4YHRA 2HIKB 1W60A 3P87A 5A6DA 1RXZA 5H0TA 1UL1A 1PLRA 2IO4A 2IX2B 5HACA 1DMLA 2HIKC 1IZ5A 4RJFA 2IO4B 5DA7A 5E0TA 3A1JA 2ZVWA 3A1JC 5IY4A 3V62B 3AIXA 3IFVA 3P83A 3VKXA 3AIZA 5B7OA 1RXMA 3AIZC 5IXAA 1RWZA 2OD8A 3P91A 3A1JB 4HK1A 3AIXB 1SXJF 5JNED 4CS5A 3U60F 2ZVVA 1GE8A 1CZDA 5IWDA 1VYJA 1T6LA 3GPNA
chains in the Genus database with same CATH topology
3G65A 4L60A 3G65C 4L6PA 3FDSD 4ZTDA 1U76A 4D2GA 3HI8A 3U5ZF 3V61B 2IZOB 1B77A 3G65B 1AXCA 3U61F 5CFKA 2ZVMA 3GGRA 2Z0LA 1IZ4A 3I2MX 1U7BA 2NTIB 5AUJA 1B8HA 2IJXA 5DAIA 1YYPA 2AVTA 3GPMA 3FDSC 2IZOC 3GGRB 2HIIB 3HSLX 1VYMA 1UD9A 3LX2A 2ZVKA 1ISQA 2ZVLA 3LX1A 4TR6A 5E0UA 2AWAA 2NTIA 3WGWA 3V60B 2HIKA 1PLQA 2NTIC 3F1WA 3K4XA 2HIIA 3GGRC 2HIIC 3TBLA 3A2FB 5E0VA 2IX2A 2IX2C 4YHRA 2HIKB 1W60A 3P87A 5A6DA 1RXZA 5H0TA 1UL1A 1PLRA 2IO4A 2IX2B 5HACA 1DMLA 2HIKC 1IZ5A 4RJFA 2IO4B 5DA7A 5E0TA 3A1JA 2ZVWA 3A1JC 5IY4A 3V62B 3AIXA 3IFVA 3P83A 3VKXA 3AIZA 5B7OA 1RXMA 3AIZC 5IXAA 1RWZA 2OD8A 3P91A 3A1JB 4HK1A 3AIXB 1SXJF 5JNED 4CS5A 3U60F 2ZVVA 1GE8A 1CZDA 5IWDA 1VYJA 1T6LA 3GPNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G65 A;  4L60 A;  3G65 C;  4L6P A;  3FDS D;  4ZTD A;  1U76 A;  4D2G A;  3HI8 A;  3U5Z F;  3V61 B;  2IZO B;  1B77 A;  3G65 B;  1AXC A;  3U61 F;  5CFK A;  2ZVM A;  3GGR A;  2Z0L A;  1IZ4 A;  3I2M X;  1U7B A;  2NTI B;  5AUJ A;  1B8H A;  2IJX A;  5DAI A;  1YYP A;  2AVT A;  3GPM A;  3FDS C;  2IZO C;  3GGR B;  2HII B;  3HSL X;  1VYM A;  1UD9 A;  3LX2 A;  2ZVK A;  1ISQ A;  2ZVL A;  3LX1 A;  4TR6 A;  5E0U A;  2AWA A;  2NTI A;  3WGW A;  3V60 B;  2HIK A;  1PLQ A;  2NTI C;  3F1W A;  3K4X A;  2HII A;  3GGR C;  2HII C;  3TBL A;  3A2F B;  5E0V A;  2IX2 A;  2IX2 C;  4YHR A;  2HIK B;  1W60 A;  3P87 A;  5A6D A;  1RXZ A;  5H0T A;  1UL1 A;  1PLR A;  2IO4 A;  2IX2 B;  5HAC A;  1DML A;  2HIK C;  1IZ5 A;  4RJF A;  2IO4 B;  5DA7 A;  5E0T A;  3A1J A;  2ZVW A;  3A1J C;  5IY4 A;  3V62 B;  3AIX A;  3IFV A;  3P83 A;  3VKX A;  3AIZ A;  5B7O A;  1RXM A;  3AIZ C;  5IXA A;  1RWZ A;  2OD8 A;  3P91 A;  3A1J B;  4HK1 A;  3AIX B;  1SXJ F;  5JNE D;  4CS5 A;  3U60 F;  2ZVV A;  1GE8 A;  1CZD A;  5IWD A;  1VYJ A;  1T6L A;  3GPN A; 
#chains in the Genus database with same CATH topology
 3G65 A;  4L60 A;  3G65 C;  4L6P A;  3FDS D;  4ZTD A;  1U76 A;  4D2G A;  3HI8 A;  3U5Z F;  3V61 B;  2IZO B;  1B77 A;  3G65 B;  1AXC A;  3U61 F;  5CFK A;  2ZVM A;  3GGR A;  2Z0L A;  1IZ4 A;  3I2M X;  1U7B A;  2NTI B;  5AUJ A;  1B8H A;  2IJX A;  5DAI A;  1YYP A;  2AVT A;  3GPM A;  3FDS C;  2IZO C;  3GGR B;  2HII B;  3HSL X;  1VYM A;  1UD9 A;  3LX2 A;  2ZVK A;  1ISQ A;  2ZVL A;  3LX1 A;  4TR6 A;  5E0U A;  2AWA A;  2NTI A;  3WGW A;  3V60 B;  2HIK A;  1PLQ A;  2NTI C;  3F1W A;  3K4X A;  2HII A;  3GGR C;  2HII C;  3TBL A;  3A2F B;  5E0V A;  2IX2 A;  2IX2 C;  4YHR A;  2HIK B;  1W60 A;  3P87 A;  5A6D A;  1RXZ A;  5H0T A;  1UL1 A;  1PLR A;  2IO4 A;  2IX2 B;  5HAC A;  1DML A;  2HIK C;  1IZ5 A;  4RJF A;  2IO4 B;  5DA7 A;  5E0T A;  3A1J A;  2ZVW A;  3A1J C;  5IY4 A;  3V62 B;  3AIX A;  3IFV A;  3P83 A;  3VKX A;  3AIZ A;  5B7O A;  1RXM A;  3AIZ C;  5IXA A;  1RWZ A;  2OD8 A;  3P91 A;  3A1J B;  4HK1 A;  3AIX B;  1SXJ F;  5JNE D;  4CS5 A;  3U60 F;  2ZVV A;  1GE8 A;  1CZD A;  5IWD A;  1VYJ A;  1T6L A;  3GPN A; 
#chains in the Genus database with same CATH homology
 3G65 A;  4L60 A;  3G65 C;  4L6P A;  3FDS D;  4ZTD A;  1U76 A;  4D2G A;  3HI8 A;  3U5Z F;  3V61 B;  2IZO B;  1B77 A;  3G65 B;  1AXC A;  3U61 F;  5CFK A;  2ZVM A;  3GGR A;  2Z0L A;  1IZ4 A;  3I2M X;  1U7B A;  2NTI B;  5AUJ A;  1B8H A;  2IJX A;  5DAI A;  1YYP A;  2AVT A;  3GPM A;  3FDS C;  2IZO C;  3GGR B;  2HII B;  3HSL X;  1VYM A;  1UD9 A;  3LX2 A;  2ZVK A;  1ISQ A;  2ZVL A;  3LX1 A;  4TR6 A;  5E0U A;  2AWA A;  2NTI A;  3WGW A;  3V60 B;  2HIK A;  1PLQ A;  2NTI C;  3F1W A;  3K4X A;  2HII A;  3GGR C;  2HII C;  3TBL A;  3A2F B;  5E0V A;  2IX2 A;  2IX2 C;  4YHR A;  2HIK B;  1W60 A;  3P87 A;  5A6D A;  1RXZ A;  5H0T A;  1UL1 A;  1PLR A;  2IO4 A;  2IX2 B;  5HAC A;  1DML A;  2HIK C;  1IZ5 A;  4RJF A;  2IO4 B;  5DA7 A;  5E0T A;  3A1J A;  2ZVW A;  3A1J C;  5IY4 A;  3V62 B;  3AIX A;  3IFV A;  3P83 A;  3VKX A;  3AIZ A;  5B7O A;  1RXM A;  3AIZ C;  5IXA A;  1RWZ A;  2OD8 A;  3P91 A;  3A1J B;  4HK1 A;  3AIX B;  1SXJ F;  5JNE D;  4CS5 A;  3U60 F;  2ZVV A;  1GE8 A;  1CZD A;  5IWD A;  1VYJ A;  1T6L A;  3GPN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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