1E9JA

Solution structure of the a-subunit of human chorionic gonadotropin [including a single glcnac residue at asn52 and asn78]
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
92
structure length
92
Chain Sequence
APDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effects of the N-linked glycans on the 3D structure of the free alpha-subunit of human chorionic gonadotropin.
pubmed doi rcsb
molecule tags Glycoprotein
molecule keywords CHORIONIC GONADOTROPIN
total genus 3
structure length 92
sequence length 92
ec nomenclature
pdb deposition date 2000-10-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1e9jA00
1FL7B 5BQBA 5BQEA 4UHYA 1S4YB 2H62A 5BQ8A 3MJKA 3JVFA 1DZ7A 4GLNE 4X1JA 5HHXA 4BV4L 1VPPV 1B8KA 1HCFA 1RV6V 5HI3A 2PJYA 2VPFA 4GLSE 1CZ8V 4ZBNA 4UI2B 1BNDB 5BPUA 4HQXA 4AY9A 1AGQA 1B8MA 4MQWA 2XV7A 4QAFC 1WAQA 4XPJA 2GYZA 1NYUB 4MIDA 1XWDA 4HSAA 2VWEA 1BTGA 3BDYV 1TGKA 4UI1A 4QCIC 5HHCA 4EDWV 2X1XE 2GNNA 1TZHV 2P6AA 5AEJA 2GOOA 2GH0C 2BHKA 3B4VA 4YCGC 5E4GA 1QTYR 2IFGE 1QFWA 4EDXV 4LXRJ 1BETA 1HCNB 4HR9A 1FL7A 4FAOA 1HRPB 1PDGA 5BQ8D 3EVSB 5HK5A 5JZ7A 1BJ1V 2ASKA 1REWA 2X1WA 2C7WA 1REUA 1NYSB 1ZKZA 2VXSA 1JPYA 3E07A 1WQ9B 4UI0A 3V2AA 3BUKA 2KD3A 5FV2V 1BNDA 1M4UA 1HD4A 2FJGV 5HI4A 1TFGA 4EC7A 3FUBB 3S1KV 5HHDA 1E9JA 2H64A 4YCIC 3BMPA 1B98A 1LX5A 4KV5A 4QHUC 1FZVA 1TZIV 3KFDA 2B0UA 4LXSJ 3IJ2A 1KLAA 1MJVA 2ARPA 1HCNA 1AOCA 1SGFB 5FV1V 1VPFA 1WQ8A 2XACA 1HRPA 2QJ9A 4UHZA 2QCWA 5BQEB 1SG1A 5HI5A 3QTKA 4N1DA 5BQ8B 4ZFFC 1ES7A 3BK3A 5HK5E 2R52A 3HH2A 4KXZA 1WQ9A 3S1BV 4EFVA 5F3HI 4EAXA 1KATW 5BQCA 2QJAA 3EO1C 3MJGA 2TGIA 1BMPA 4WPBA 1WWWV 2QJBA 1KTZA 4AY9B 3V6BA 1B8MB 1MKGA 4MQWB 1LXIA 1NT3A 2FJHV 2R53A 1XWDB 2ARVA 1TGJA 1KLCA 1FLTV 2GYRA 5F3BC 2QCQA 3QB4A 4KZNA 4MPLA 2QR0C 3RJRA 2V5EB 3SEKB 1MKKA 1M4UL 1QFWB 5HHVA 4HQUA 3P9WA
chains in the Genus database with same CATH superfamily
1FL7B 5BQBA 5BQEA 4UHYA 1S4YB 2H62A 5BQ8A 3MJKA 3JVFA 1DZ7A 4GLNE 4X1JA 5HHXA 4BV4L 1VPPV 1B8KA 1HCFA 1RV6V 5HI3A 2PJYA 2VPFA 4GLSE 1CZ8V 4ZBNA 4UI2B 1BNDB 5BPUA 4HQXA 4AY9A 1AGQA 1B8MA 4MQWA 2XV7A 4QAFC 1WAQA 4XPJA 2GYZA 1NYUB 4MIDA 1XWDA 4HSAA 2VWEA 1BTGA 3BDYV 1TGKA 4UI1A 4QCIC 5HHCA 4EDWV 2X1XE 2GNNA 1TZHV 2P6AA 5AEJA 2GOOA 2GH0C 2BHKA 3B4VA 4YCGC 5E4GA 1QTYR 2IFGE 1QFWA 4EDXV 4LXRJ 1BETA 1HCNB 4HR9A 1FL7A 4FAOA 1HRPB 1PDGA 5BQ8D 3EVSB 5HK5A 5JZ7A 1BJ1V 2ASKA 1REWA 2X1WA 2C7WA 1REUA 1NYSB 1ZKZA 2VXSA 1JPYA 3E07A 1WQ9B 4UI0A 3V2AA 3BUKA 2KD3A 5FV2V 1BNDA 1M4UA 1HD4A 2FJGV 5HI4A 1TFGA 4EC7A 3FUBB 3S1KV 5HHDA 1E9JA 2H64A 4YCIC 3BMPA 1B98A 1LX5A 4KV5A 4QHUC 1FZVA 1TZIV 3KFDA 2B0UA 4LXSJ 3IJ2A 1KLAA 1MJVA 2ARPA 1HCNA 1AOCA 1SGFB 5FV1V 1VPFA 1WQ8A 2XACA 1HRPA 2QJ9A 4UHZA 2QCWA 5BQEB 1SG1A 5HI5A 3QTKA 4N1DA 5BQ8B 4ZFFC 1ES7A 3BK3A 5HK5E 2R52A 3HH2A 4KXZA 1WQ9A 3S1BV 4EFVA 5F3HI 4EAXA 1KATW 5BQCA 2QJAA 3EO1C 3MJGA 2TGIA 1BMPA 4WPBA 1WWWV 2QJBA 1KTZA 4AY9B 3V6BA 1B8MB 1MKGA 4MQWB 1LXIA 1NT3A 2FJHV 2R53A 1XWDB 2ARVA 1TGJA 1KLCA 1FLTV 2GYRA 5F3BC 2QCQA 3QB4A 4KZNA 4MPLA 2QR0C 3RJRA 2V5EB 3SEKB 1MKKA 1M4UL 1QFWB 5HHVA 4HQUA 3P9WA
chains in the Genus database with same CATH topology
1FL7B 5BQBA 5BQEA 4UHYA 1S4YB 2H62A 5BQ8A 3MJKA 3JVFA 1DZ7A 4GLNE 4X1JA 5HHXA 4BV4L 1VPPV 1B8KA 1HCFA 1RV6V 5HI3A 2PJYA 2VPFA 4GLSE 1CZ8V 4ZBNA 4UI2B 1BNDB 5BPUA 4HQXA 4AY9A 1AGQA 1B8MA 4MQWA 2XV7A 4QAFC 1WAQA 4XPJA 2GYZA 1NYUB 4MIDA 1XWDA 4HSAA 2VWEA 1BTGA 3BDYV 1TGKA 4UI1A 4QCIC 5HHCA 4EDWV 2X1XE 2GNNA 1TZHV 2P6AA 5AEJA 2GOOA 2GH0C 2BHKA 3B4VA 4YCGC 5E4GA 1QTYR 2IFGE 1QFWA 4EDXV 4LXRJ 1BETA 1HCNB 4HR9A 1FL7A 4FAOA 1HRPB 1PDGA 5BQ8D 3EVSB 5HK5A 5JZ7A 1BJ1V 2ASKA 1REWA 2X1WA 2C7WA 1REUA 1NYSB 1ZKZA 2VXSA 1JPYA 3E07A 1WQ9B 4UI0A 3V2AA 3BUKA 2KD3A 5FV2V 1BNDA 1M4UA 1HD4A 2FJGV 5HI4A 1TFGA 4EC7A 3FUBB 3S1KV 5HHDA 1E9JA 2H64A 4YCIC 3BMPA 1B98A 1LX5A 4KV5A 4QHUC 1FZVA 1TZIV 3KFDA 2B0UA 4LXSJ 3IJ2A 1KLAA 1MJVA 2ARPA 1HCNA 1AOCA 1SGFB 5FV1V 1VPFA 1WQ8A 2XACA 1HRPA 2QJ9A 4UHZA 2QCWA 5BQEB 1SG1A 5HI5A 3QTKA 4N1DA 5BQ8B 4ZFFC 1ES7A 3BK3A 5HK5E 2R52A 3HH2A 4KXZA 1WQ9A 3S1BV 4EFVA 5F3HI 4EAXA 1KATW 5BQCA 2QJAA 3EO1C 3MJGA 2TGIA 1BMPA 4WPBA 1WWWV 2QJBA 1KTZA 4AY9B 3V6BA 1B8MB 1MKGA 4MQWB 1LXIA 1NT3A 2FJHV 2R53A 1XWDB 2ARVA 1TGJA 1KLCA 1FLTV 2GYRA 5F3BC 2QCQA 3QB4A 4KZNA 4MPLA 2QR0C 3RJRA 2V5EB 3SEKB 1MKKA 1M4UL 1QFWB 5HHVA 4HQUA 3P9WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FL7 B;  5BQB A;  5BQE A;  4UHY A;  1S4Y B;  2H62 A;  5BQ8 A;  3MJK A;  3JVF A;  1DZ7 A;  4GLN E;  4X1J A;  5HHX A;  4BV4 L;  1VPP V;  1B8K A;  1HCF A;  1RV6 V;  5HI3 A;  2PJY A;  2VPF A;  4GLS E;  1CZ8 V;  4ZBN A;  4UI2 B;  1BND B;  5BPU A;  4HQX A;  4AY9 A;  1AGQ A;  1B8M A;  4MQW A;  2XV7 A;  4QAF C;  1WAQ A;  4XPJ A;  2GYZ A;  1NYU B;  4MID A;  1XWD A;  4HSA A;  2VWE A;  1BTG A;  3BDY V;  1TGK A;  4UI1 A;  4QCI C;  5HHC A;  4EDW V;  2X1X E;  2GNN A;  1TZH V;  2P6A A;  5AEJ A;  2GOO A;  2GH0 C;  2BHK A;  3B4V A;  4YCG C;  5E4G A;  1QTY R;  2IFG E;  1QFW A;  4EDX V;  4LXR J;  1BET A;  1HCN B;  4HR9 A;  1FL7 A;  4FAO A;  1HRP B;  1PDG A;  5BQ8 D;  3EVS B;  5HK5 A;  5JZ7 A;  1BJ1 V;  2ASK A;  1REW A;  2X1W A;  2C7W A;  1REU A;  1NYS B;  1ZKZ A;  2VXS A;  1JPY A;  3E07 A;  1WQ9 B;  4UI0 A;  3V2A A;  3BUK A;  2KD3 A;  5FV2 V;  1BND A;  1M4U A;  1HD4 A;  2FJG V;  5HI4 A;  1TFG A;  4EC7 A;  3FUB B;  3S1K V;  5HHD A;  1E9J A;  2H64 A;  4YCI C;  3BMP A;  1B98 A;  1LX5 A;  4KV5 A;  4QHU C;  1FZV A;  1TZI V;  3KFD A;  2B0U A;  4LXS J;  3IJ2 A;  1KLA A;  1MJV A;  2ARP A;  1HCN A;  1AOC A;  1SGF B;  5FV1 V;  1VPF A;  1WQ8 A;  2XAC A;  1HRP A;  2QJ9 A;  4UHZ A;  2QCW A;  5BQE B;  1SG1 A;  5HI5 A;  3QTK A;  4N1D A;  5BQ8 B;  4ZFF C;  1ES7 A;  3BK3 A;  5HK5 E;  2R52 A;  3HH2 A;  4KXZ A;  1WQ9 A;  3S1B V;  4EFV A;  5F3H I;  4EAX A;  1KAT W;  5BQC A;  2QJA A;  3EO1 C;  3MJG A;  2TGI A;  1BMP A;  4WPB A;  1WWW V;  2QJB A;  1KTZ A;  4AY9 B;  3V6B A;  1B8M B;  1MKG A;  4MQW B;  1LXI A;  1NT3 A;  2FJH V;  2R53 A;  1XWD B;  2ARV A;  1TGJ A;  1KLC A;  1FLT V;  2GYR A;  5F3B C;  2QCQ A;  3QB4 A;  4KZN A;  4MPL A;  2QR0 C;  3RJR A;  2V5E B;  3SEK B;  1MKK A;  1M4U L;  1QFW B;  5HHV A;  4HQU A;  3P9W A; 
#chains in the Genus database with same CATH topology
 1FL7 B;  5BQB A;  5BQE A;  4UHY A;  1S4Y B;  2H62 A;  5BQ8 A;  3MJK A;  3JVF A;  1DZ7 A;  4GLN E;  4X1J A;  5HHX A;  4BV4 L;  1VPP V;  1B8K A;  1HCF A;  1RV6 V;  5HI3 A;  2PJY A;  2VPF A;  4GLS E;  1CZ8 V;  4ZBN A;  4UI2 B;  1BND B;  5BPU A;  4HQX A;  4AY9 A;  1AGQ A;  1B8M A;  4MQW A;  2XV7 A;  4QAF C;  1WAQ A;  4XPJ A;  2GYZ A;  1NYU B;  4MID A;  1XWD A;  4HSA A;  2VWE A;  1BTG A;  3BDY V;  1TGK A;  4UI1 A;  4QCI C;  5HHC A;  4EDW V;  2X1X E;  2GNN A;  1TZH V;  2P6A A;  5AEJ A;  2GOO A;  2GH0 C;  2BHK A;  3B4V A;  4YCG C;  5E4G A;  1QTY R;  2IFG E;  1QFW A;  4EDX V;  4LXR J;  1BET A;  1HCN B;  4HR9 A;  1FL7 A;  4FAO A;  1HRP B;  1PDG A;  5BQ8 D;  3EVS B;  5HK5 A;  5JZ7 A;  1BJ1 V;  2ASK A;  1REW A;  2X1W A;  2C7W A;  1REU A;  1NYS B;  1ZKZ A;  2VXS A;  1JPY A;  3E07 A;  1WQ9 B;  4UI0 A;  3V2A A;  3BUK A;  2KD3 A;  5FV2 V;  1BND A;  1M4U A;  1HD4 A;  2FJG V;  5HI4 A;  1TFG A;  4EC7 A;  3FUB B;  3S1K V;  5HHD A;  1E9J A;  2H64 A;  4YCI C;  3BMP A;  1B98 A;  1LX5 A;  4KV5 A;  4QHU C;  1FZV A;  1TZI V;  3KFD A;  2B0U A;  4LXS J;  3IJ2 A;  1KLA A;  1MJV A;  2ARP A;  1HCN A;  1AOC A;  1SGF B;  5FV1 V;  1VPF A;  1WQ8 A;  2XAC A;  1HRP A;  2QJ9 A;  4UHZ A;  2QCW A;  5BQE B;  1SG1 A;  5HI5 A;  3QTK A;  4N1D A;  5BQ8 B;  4ZFF C;  1ES7 A;  3BK3 A;  5HK5 E;  2R52 A;  3HH2 A;  4KXZ A;  1WQ9 A;  3S1B V;  4EFV A;  5F3H I;  4EAX A;  1KAT W;  5BQC A;  2QJA A;  3EO1 C;  3MJG A;  2TGI A;  1BMP A;  4WPB A;  1WWW V;  2QJB A;  1KTZ A;  4AY9 B;  3V6B A;  1B8M B;  1MKG A;  4MQW B;  1LXI A;  1NT3 A;  2FJH V;  2R53 A;  1XWD B;  2ARV A;  1TGJ A;  1KLC A;  1FLT V;  2GYR A;  5F3B C;  2QCQ A;  3QB4 A;  4KZN A;  4MPL A;  2QR0 C;  3RJR A;  2V5E B;  3SEK B;  1MKK A;  1M4U L;  1QFW B;  5HHV A;  4HQU A;  3P9W A; 
#chains in the Genus database with same CATH homology
 1FL7 B;  5BQB A;  5BQE A;  4UHY A;  1S4Y B;  2H62 A;  5BQ8 A;  3MJK A;  3JVF A;  1DZ7 A;  4GLN E;  4X1J A;  5HHX A;  4BV4 L;  1VPP V;  1B8K A;  1HCF A;  1RV6 V;  5HI3 A;  2PJY A;  2VPF A;  4GLS E;  1CZ8 V;  4ZBN A;  4UI2 B;  1BND B;  5BPU A;  4HQX A;  4AY9 A;  1AGQ A;  1B8M A;  4MQW A;  2XV7 A;  4QAF C;  1WAQ A;  4XPJ A;  2GYZ A;  1NYU B;  4MID A;  1XWD A;  4HSA A;  2VWE A;  1BTG A;  3BDY V;  1TGK A;  4UI1 A;  4QCI C;  5HHC A;  4EDW V;  2X1X E;  2GNN A;  1TZH V;  2P6A A;  5AEJ A;  2GOO A;  2GH0 C;  2BHK A;  3B4V A;  4YCG C;  5E4G A;  1QTY R;  2IFG E;  1QFW A;  4EDX V;  4LXR J;  1BET A;  1HCN B;  4HR9 A;  1FL7 A;  4FAO A;  1HRP B;  1PDG A;  5BQ8 D;  3EVS B;  5HK5 A;  5JZ7 A;  1BJ1 V;  2ASK A;  1REW A;  2X1W A;  2C7W A;  1REU A;  1NYS B;  1ZKZ A;  2VXS A;  1JPY A;  3E07 A;  1WQ9 B;  4UI0 A;  3V2A A;  3BUK A;  2KD3 A;  5FV2 V;  1BND A;  1M4U A;  1HD4 A;  2FJG V;  5HI4 A;  1TFG A;  4EC7 A;  3FUB B;  3S1K V;  5HHD A;  1E9J A;  2H64 A;  4YCI C;  3BMP A;  1B98 A;  1LX5 A;  4KV5 A;  4QHU C;  1FZV A;  1TZI V;  3KFD A;  2B0U A;  4LXS J;  3IJ2 A;  1KLA A;  1MJV A;  2ARP A;  1HCN A;  1AOC A;  1SGF B;  5FV1 V;  1VPF A;  1WQ8 A;  2XAC A;  1HRP A;  2QJ9 A;  4UHZ A;  2QCW A;  5BQE B;  1SG1 A;  5HI5 A;  3QTK A;  4N1D A;  5BQ8 B;  4ZFF C;  1ES7 A;  3BK3 A;  5HK5 E;  2R52 A;  3HH2 A;  4KXZ A;  1WQ9 A;  3S1B V;  4EFV A;  5F3H I;  4EAX A;  1KAT W;  5BQC A;  2QJA A;  3EO1 C;  3MJG A;  2TGI A;  1BMP A;  4WPB A;  1WWW V;  2QJB A;  1KTZ A;  4AY9 B;  3V6B A;  1B8M B;  1MKG A;  4MQW B;  1LXI A;  1NT3 A;  2FJH V;  2R53 A;  1XWD B;  2ARV A;  1TGJ A;  1KLC A;  1FLT V;  2GYR A;  5F3B C;  2QCQ A;  3QB4 A;  4KZN A;  4MPL A;  2QR0 C;  3RJR A;  2V5E B;  3SEK B;  1MKK A;  1M4U L;  1QFW B;  5HHV A;  4HQU A;  3P9W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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