1HRPB

Crystal structure of human chorionic gonadotropin
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
110
structure length
110
Chain Sequence
KEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVLPALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDCGGPKDHPLTCD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human chorionic gonadotropin.
pubmed doi rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords HUMAN CHORIONIC GONADOTROPIN
total genus 7
structure length 110
sequence length 110
ec nomenclature
pdb deposition date 1994-08-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00007 Cys_knot Cystine-knot domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1hrpB00
2VXSA 2X1XE 2GH0C 3RJRA 1MKKA 4GLSE 1XWDA 1QFWA 3SEKB 2C7WA 3FUBB 2QCQA 2IFGE 4QAFC 4BV4L 4XPJA 3QTKA 1WWWV 3EO1C 2KD3A 4HSAA 4MPLA 2FJHV 1WQ9B 3E07A 3HH2A 1B8MB 1TGJA 2GOOA 2B0UA 4EFVA 1NYSB 3B4VA 3MJGA 5JZ7A 4QCIC 2BHKA 1MKGA 1PDGA 5HHVA 5HI3A 4EAXA 5BPUA 5BQEA 1FZVA 5AEJA 4YCIC 1NYUB 1HRPA 1DZ7A 3BMPA 5FV1V 1TZHV 4AY9A 4MIDA 5BQ8B 1KATW 2H62A 4MQWA 2H64A 1FLTV 4YCGC 4HQXA 1FL7B 4UHYA 5E4GA 4UHZA 4WPBA 1AGQA 2GYRA 1E9JA 1CZ8V 1WQ9A 1KLCA 5HK5E 1SG1A 1HCNB 1BNDB 4QHUC 4UI2B 5HK5A 1B8MA 1TZIV 5BQ8D 2QJAA 1VPPV 5HHXA 4HR9A 1QTYR 2FJGV 3QB4A 1JPYA 1RV6V 2TGIA 1WAQA 4EDWV 2QJ9A 4ZFFC 5HHDA 3V6BA 2R52A 1XWDB 2QJBA 1HD4A 1KLAA 3S1KV 2VPFA 1KTZA 5BQ8A 1TFGA 5BQCA 2ARVA 1REWA 1FL7A 4ZBNA 1REUA 3V2AA 2X1WA 3BK3A 2GYZA 4GLNE 1SGFB 3EVSB 2VWEA 2QCWA 1HCNA 1BNDA 3BDYV 3JVFA 4FAOA 1HCFA 1WQ8A 1BJ1V 4KXZA 4LXRJ 2V5EB 5BQBA 2QR0C 3MJKA 5HHCA 1BTGA 1TGKA 5F3HI 4KZNA 5HI5A 3S1BV 1QFWB 2R53A 4UI0A 4X1JA 4UI1A 1MJVA 5FV2V 1B98A 1NT3A 1LXIA 1VPFA 2GNNA 3P9WA 2ASKA 2P6AA 2PJYA 3IJ2A 5F3BC 4LXSJ 4N1DA 1M4UL 1S4YB 2XV7A 1LX5A 4HQUA 1BMPA 1ES7A 1BETA 1M4UA 4EC7A 5BQEB 4EDXV 3BUKA 1AOCA 1HRPB 2XACA 1ZKZA 2ARPA 4AY9B 4KV5A 3KFDA 5HI4A 4MQWB 1B8KA
chains in the Genus database with same CATH superfamily
2VXSA 2X1XE 2GH0C 3RJRA 1MKKA 4GLSE 1XWDA 1QFWA 3SEKB 2C7WA 3FUBB 2QCQA 2IFGE 4QAFC 4BV4L 4XPJA 3QTKA 1WWWV 3EO1C 2KD3A 4HSAA 4MPLA 2FJHV 1WQ9B 3E07A 3HH2A 1B8MB 1TGJA 2GOOA 2B0UA 4EFVA 1NYSB 3B4VA 3MJGA 5JZ7A 4QCIC 2BHKA 1MKGA 1PDGA 5HHVA 5HI3A 4EAXA 5BPUA 5BQEA 1FZVA 5AEJA 4YCIC 1NYUB 1HRPA 1DZ7A 3BMPA 5FV1V 1TZHV 4AY9A 4MIDA 5BQ8B 1KATW 2H62A 4MQWA 2H64A 1FLTV 4YCGC 4HQXA 1FL7B 4UHYA 5E4GA 4UHZA 4WPBA 1AGQA 2GYRA 1E9JA 1CZ8V 1WQ9A 1KLCA 5HK5E 1SG1A 1HCNB 1BNDB 4QHUC 4UI2B 5HK5A 1B8MA 1TZIV 5BQ8D 2QJAA 1VPPV 5HHXA 4HR9A 1QTYR 2FJGV 3QB4A 1JPYA 1RV6V 2TGIA 1WAQA 4EDWV 2QJ9A 4ZFFC 5HHDA 3V6BA 2R52A 1XWDB 2QJBA 1HD4A 1KLAA 3S1KV 2VPFA 1KTZA 5BQ8A 1TFGA 5BQCA 2ARVA 1REWA 1FL7A 4ZBNA 1REUA 3V2AA 2X1WA 3BK3A 2GYZA 4GLNE 1SGFB 3EVSB 2VWEA 2QCWA 1HCNA 1BNDA 3BDYV 3JVFA 4FAOA 1HCFA 1WQ8A 1BJ1V 4KXZA 4LXRJ 2V5EB 5BQBA 2QR0C 3MJKA 5HHCA 1BTGA 1TGKA 5F3HI 4KZNA 5HI5A 3S1BV 1QFWB 2R53A 4UI0A 4X1JA 4UI1A 1MJVA 5FV2V 1B98A 1NT3A 1LXIA 1VPFA 2GNNA 3P9WA 2ASKA 2P6AA 2PJYA 3IJ2A 5F3BC 4LXSJ 4N1DA 1M4UL 1S4YB 2XV7A 1LX5A 4HQUA 1BMPA 1ES7A 1BETA 1M4UA 4EC7A 5BQEB 4EDXV 3BUKA 1AOCA 1HRPB 2XACA 1ZKZA 2ARPA 4AY9B 4KV5A 3KFDA 5HI4A 4MQWB 1B8KA
chains in the Genus database with same CATH topology
2VXSA 2X1XE 2GH0C 3RJRA 1MKKA 4GLSE 1XWDA 1QFWA 3SEKB 2C7WA 3FUBB 2QCQA 2IFGE 4QAFC 4BV4L 4XPJA 3QTKA 1WWWV 3EO1C 2KD3A 4HSAA 4MPLA 2FJHV 1WQ9B 3E07A 3HH2A 1B8MB 1TGJA 2GOOA 2B0UA 4EFVA 1NYSB 3B4VA 3MJGA 5JZ7A 4QCIC 2BHKA 1MKGA 1PDGA 5HHVA 5HI3A 4EAXA 5BPUA 5BQEA 1FZVA 5AEJA 4YCIC 1NYUB 1HRPA 1DZ7A 3BMPA 5FV1V 1TZHV 4AY9A 4MIDA 5BQ8B 1KATW 2H62A 4MQWA 2H64A 1FLTV 4YCGC 4HQXA 1FL7B 4UHYA 5E4GA 4UHZA 4WPBA 1AGQA 2GYRA 1E9JA 1CZ8V 1WQ9A 1KLCA 5HK5E 1SG1A 1HCNB 1BNDB 4QHUC 4UI2B 5HK5A 1B8MA 1TZIV 5BQ8D 2QJAA 1VPPV 5HHXA 4HR9A 1QTYR 2FJGV 3QB4A 1JPYA 1RV6V 2TGIA 1WAQA 4EDWV 2QJ9A 4ZFFC 5HHDA 3V6BA 2R52A 1XWDB 2QJBA 1HD4A 1KLAA 3S1KV 2VPFA 1KTZA 5BQ8A 1TFGA 5BQCA 2ARVA 1REWA 1FL7A 4ZBNA 1REUA 3V2AA 2X1WA 3BK3A 2GYZA 4GLNE 1SGFB 3EVSB 2VWEA 2QCWA 1HCNA 1BNDA 3BDYV 3JVFA 4FAOA 1HCFA 1WQ8A 1BJ1V 4KXZA 4LXRJ 2V5EB 5BQBA 2QR0C 3MJKA 5HHCA 1BTGA 1TGKA 5F3HI 4KZNA 5HI5A 3S1BV 1QFWB 2R53A 4UI0A 4X1JA 4UI1A 1MJVA 5FV2V 1B98A 1NT3A 1LXIA 1VPFA 2GNNA 3P9WA 2ASKA 2P6AA 2PJYA 3IJ2A 5F3BC 4LXSJ 4N1DA 1M4UL 1S4YB 2XV7A 1LX5A 4HQUA 1BMPA 1ES7A 1BETA 1M4UA 4EC7A 5BQEB 4EDXV 3BUKA 1AOCA 1HRPB 2XACA 1ZKZA 2ARPA 4AY9B 4KV5A 3KFDA 5HI4A 4MQWB 1B8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VXS A;  2X1X E;  2GH0 C;  3RJR A;  1MKK A;  4GLS E;  1XWD A;  1QFW A;  3SEK B;  2C7W A;  3FUB B;  2QCQ A;  2IFG E;  4QAF C;  4BV4 L;  4XPJ A;  3QTK A;  1WWW V;  3EO1 C;  2KD3 A;  4HSA A;  4MPL A;  2FJH V;  1WQ9 B;  3E07 A;  3HH2 A;  1B8M B;  1TGJ A;  2GOO A;  2B0U A;  4EFV A;  1NYS B;  3B4V A;  3MJG A;  5JZ7 A;  4QCI C;  2BHK A;  1MKG A;  1PDG A;  5HHV A;  5HI3 A;  4EAX A;  5BPU A;  5BQE A;  1FZV A;  5AEJ A;  4YCI C;  1NYU B;  1HRP A;  1DZ7 A;  3BMP A;  5FV1 V;  1TZH V;  4AY9 A;  4MID A;  5BQ8 B;  1KAT W;  2H62 A;  4MQW A;  2H64 A;  1FLT V;  4YCG C;  4HQX A;  1FL7 B;  4UHY A;  5E4G A;  4UHZ A;  4WPB A;  1AGQ A;  2GYR A;  1E9J A;  1CZ8 V;  1WQ9 A;  1KLC A;  5HK5 E;  1SG1 A;  1HCN B;  1BND B;  4QHU C;  4UI2 B;  5HK5 A;  1B8M A;  1TZI V;  5BQ8 D;  2QJA A;  1VPP V;  5HHX A;  4HR9 A;  1QTY R;  2FJG V;  3QB4 A;  1JPY A;  1RV6 V;  2TGI A;  1WAQ A;  4EDW V;  2QJ9 A;  4ZFF C;  5HHD A;  3V6B A;  2R52 A;  1XWD B;  2QJB A;  1HD4 A;  1KLA A;  3S1K V;  2VPF A;  1KTZ A;  5BQ8 A;  1TFG A;  5BQC A;  2ARV A;  1REW A;  1FL7 A;  4ZBN A;  1REU A;  3V2A A;  2X1W A;  3BK3 A;  2GYZ A;  4GLN E;  1SGF B;  3EVS B;  2VWE A;  2QCW A;  1HCN A;  1BND A;  3BDY V;  3JVF A;  4FAO A;  1HCF A;  1WQ8 A;  1BJ1 V;  4KXZ A;  4LXR J;  2V5E B;  5BQB A;  2QR0 C;  3MJK A;  5HHC A;  1BTG A;  1TGK A;  5F3H I;  4KZN A;  5HI5 A;  3S1B V;  1QFW B;  2R53 A;  4UI0 A;  4X1J A;  4UI1 A;  1MJV A;  5FV2 V;  1B98 A;  1NT3 A;  1LXI A;  1VPF A;  2GNN A;  3P9W A;  2ASK A;  2P6A A;  2PJY A;  3IJ2 A;  5F3B C;  4LXS J;  4N1D A;  1M4U L;  1S4Y B;  2XV7 A;  1LX5 A;  4HQU A;  1BMP A;  1ES7 A;  1BET A;  1M4U A;  4EC7 A;  5BQE B;  4EDX V;  3BUK A;  1AOC A;  1HRP B;  2XAC A;  1ZKZ A;  2ARP A;  4AY9 B;  4KV5 A;  3KFD A;  5HI4 A;  4MQW B;  1B8K A; 
#chains in the Genus database with same CATH topology
 2VXS A;  2X1X E;  2GH0 C;  3RJR A;  1MKK A;  4GLS E;  1XWD A;  1QFW A;  3SEK B;  2C7W A;  3FUB B;  2QCQ A;  2IFG E;  4QAF C;  4BV4 L;  4XPJ A;  3QTK A;  1WWW V;  3EO1 C;  2KD3 A;  4HSA A;  4MPL A;  2FJH V;  1WQ9 B;  3E07 A;  3HH2 A;  1B8M B;  1TGJ A;  2GOO A;  2B0U A;  4EFV A;  1NYS B;  3B4V A;  3MJG A;  5JZ7 A;  4QCI C;  2BHK A;  1MKG A;  1PDG A;  5HHV A;  5HI3 A;  4EAX A;  5BPU A;  5BQE A;  1FZV A;  5AEJ A;  4YCI C;  1NYU B;  1HRP A;  1DZ7 A;  3BMP A;  5FV1 V;  1TZH V;  4AY9 A;  4MID A;  5BQ8 B;  1KAT W;  2H62 A;  4MQW A;  2H64 A;  1FLT V;  4YCG C;  4HQX A;  1FL7 B;  4UHY A;  5E4G A;  4UHZ A;  4WPB A;  1AGQ A;  2GYR A;  1E9J A;  1CZ8 V;  1WQ9 A;  1KLC A;  5HK5 E;  1SG1 A;  1HCN B;  1BND B;  4QHU C;  4UI2 B;  5HK5 A;  1B8M A;  1TZI V;  5BQ8 D;  2QJA A;  1VPP V;  5HHX A;  4HR9 A;  1QTY R;  2FJG V;  3QB4 A;  1JPY A;  1RV6 V;  2TGI A;  1WAQ A;  4EDW V;  2QJ9 A;  4ZFF C;  5HHD A;  3V6B A;  2R52 A;  1XWD B;  2QJB A;  1HD4 A;  1KLA A;  3S1K V;  2VPF A;  1KTZ A;  5BQ8 A;  1TFG A;  5BQC A;  2ARV A;  1REW A;  1FL7 A;  4ZBN A;  1REU A;  3V2A A;  2X1W A;  3BK3 A;  2GYZ A;  4GLN E;  1SGF B;  3EVS B;  2VWE A;  2QCW A;  1HCN A;  1BND A;  3BDY V;  3JVF A;  4FAO A;  1HCF A;  1WQ8 A;  1BJ1 V;  4KXZ A;  4LXR J;  2V5E B;  5BQB A;  2QR0 C;  3MJK A;  5HHC A;  1BTG A;  1TGK A;  5F3H I;  4KZN A;  5HI5 A;  3S1B V;  1QFW B;  2R53 A;  4UI0 A;  4X1J A;  4UI1 A;  1MJV A;  5FV2 V;  1B98 A;  1NT3 A;  1LXI A;  1VPF A;  2GNN A;  3P9W A;  2ASK A;  2P6A A;  2PJY A;  3IJ2 A;  5F3B C;  4LXS J;  4N1D A;  1M4U L;  1S4Y B;  2XV7 A;  1LX5 A;  4HQU A;  1BMP A;  1ES7 A;  1BET A;  1M4U A;  4EC7 A;  5BQE B;  4EDX V;  3BUK A;  1AOC A;  1HRP B;  2XAC A;  1ZKZ A;  2ARP A;  4AY9 B;  4KV5 A;  3KFD A;  5HI4 A;  4MQW B;  1B8K A; 
#chains in the Genus database with same CATH homology
 2VXS A;  2X1X E;  2GH0 C;  3RJR A;  1MKK A;  4GLS E;  1XWD A;  1QFW A;  3SEK B;  2C7W A;  3FUB B;  2QCQ A;  2IFG E;  4QAF C;  4BV4 L;  4XPJ A;  3QTK A;  1WWW V;  3EO1 C;  2KD3 A;  4HSA A;  4MPL A;  2FJH V;  1WQ9 B;  3E07 A;  3HH2 A;  1B8M B;  1TGJ A;  2GOO A;  2B0U A;  4EFV A;  1NYS B;  3B4V A;  3MJG A;  5JZ7 A;  4QCI C;  2BHK A;  1MKG A;  1PDG A;  5HHV A;  5HI3 A;  4EAX A;  5BPU A;  5BQE A;  1FZV A;  5AEJ A;  4YCI C;  1NYU B;  1HRP A;  1DZ7 A;  3BMP A;  5FV1 V;  1TZH V;  4AY9 A;  4MID A;  5BQ8 B;  1KAT W;  2H62 A;  4MQW A;  2H64 A;  1FLT V;  4YCG C;  4HQX A;  1FL7 B;  4UHY A;  5E4G A;  4UHZ A;  4WPB A;  1AGQ A;  2GYR A;  1E9J A;  1CZ8 V;  1WQ9 A;  1KLC A;  5HK5 E;  1SG1 A;  1HCN B;  1BND B;  4QHU C;  4UI2 B;  5HK5 A;  1B8M A;  1TZI V;  5BQ8 D;  2QJA A;  1VPP V;  5HHX A;  4HR9 A;  1QTY R;  2FJG V;  3QB4 A;  1JPY A;  1RV6 V;  2TGI A;  1WAQ A;  4EDW V;  2QJ9 A;  4ZFF C;  5HHD A;  3V6B A;  2R52 A;  1XWD B;  2QJB A;  1HD4 A;  1KLA A;  3S1K V;  2VPF A;  1KTZ A;  5BQ8 A;  1TFG A;  5BQC A;  2ARV A;  1REW A;  1FL7 A;  4ZBN A;  1REU A;  3V2A A;  2X1W A;  3BK3 A;  2GYZ A;  4GLN E;  1SGF B;  3EVS B;  2VWE A;  2QCW A;  1HCN A;  1BND A;  3BDY V;  3JVF A;  4FAO A;  1HCF A;  1WQ8 A;  1BJ1 V;  4KXZ A;  4LXR J;  2V5E B;  5BQB A;  2QR0 C;  3MJK A;  5HHC A;  1BTG A;  1TGK A;  5F3H I;  4KZN A;  5HI5 A;  3S1B V;  1QFW B;  2R53 A;  4UI0 A;  4X1J A;  4UI1 A;  1MJV A;  5FV2 V;  1B98 A;  1NT3 A;  1LXI A;  1VPF A;  2GNN A;  3P9W A;  2ASK A;  2P6A A;  2PJY A;  3IJ2 A;  5F3B C;  4LXS J;  4N1D A;  1M4U L;  1S4Y B;  2XV7 A;  1LX5 A;  4HQU A;  1BMP A;  1ES7 A;  1BET A;  1M4U A;  4EC7 A;  5BQE B;  4EDX V;  3BUK A;  1AOC A;  1HRP B;  2XAC A;  1ZKZ A;  2ARP A;  4AY9 B;  4KV5 A;  3KFD A;  5HI4 A;  4MQW B;  1B8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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