1REUA

Structure of the bone morphogenetic protein 2 mutant l51p
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
103
structure length
103
Chain Sequence
SSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPPADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular recognition of BMP-2 and BMP receptor IA.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords bone morphogenetic protein 2
total genus 16
structure length 103
sequence length 103
ec nomenclature
pdb deposition date 2003-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00019 TGF_beta Transforming growth factor beta like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1reuA00
5HI4A 5AEJA 2QJBA 5HHDA 1WQ9B 4UI2B 1JPYA 2GOOA 5FV2V 4WPBA 3BMPA 4AY9B 4QCIC 1HCFA 3V6BA 4KV5A 5BPUA 1B98A 1RV6V 5BQEB 5F3BC 1M4UL 1TGJA 2BHKA 2QCQA 1KTZA 3BK3A 1FZVA 2VPFA 3BUKA 3S1KV 4EC7A 3IJ2A 1PDGA 3JVFA 1HRPA 1XWDA 2QJ9A 1TGKA 5FV1V 1TFGA 4HR9A 4X1JA 1KLAA 3E07A 5JZ7A 3B4VA 1E9JA 1FL7B 2GH0C 1NYSB 4UHZA 3V2AA 4ZBNA 1MJVA 1BTGA 1SGFB 3EVSB 1KATW 1HCNA 2ASKA 2R52A 4UI1A 1KLCA 2R53A 2XV7A 1WQ8A 1FLTV 1ZKZA 5BQ8A 1QFWA 1BETA 1BJ1V 3EO1C 4YCIC 2FJHV 4BV4L 1B8MB 2H62A 4EAXA 2QJAA 3RJRA 1WWWV 4GLSE 4HQXA 4MIDA 1BNDB 1ES7A 1TZHV 3SEKB 4HQUA 5HI5A 1MKGA 2IFGE 1QTYR 1DZ7A 2KD3A 2V5EB 5HI3A 2B0UA 1TZIV 3FUBB 2X1WA 4HSAA 1M4UA 5HHVA 2VWEA 3QB4A 5HK5E 1REWA 4AY9A 1LXIA 4MQWA 4KXZA 2PJYA 5E4GA 1WAQA 5BQEA 3QTKA 2QCWA 1B8KA 4UHYA 3MJGA 1CZ8V 1LX5A 2P6AA 2VXSA 3BDYV 4FAOA 3KFDA 1HRPB 1NYUB 1VPFA 1XWDB 3P9WA 4YCGC 5BQBA 2ARVA 3HH2A 2FJGV 2C7WA 5BQCA 4KZNA 1FL7A 2GYZA 1WQ9A 1HCNB 2XACA 4MQWB 5HHCA 2X1XE 4QHUC 5HK5A 2TGIA 5F3HI 4ZFFC 4MPLA 4QAFC 4LXSJ 5BQ8B 2GYRA 4UI0A 1SG1A 1QFWB 5BQ8D 1HD4A 2GNNA 1MKKA 2QR0C 5HHXA 1VPPV 2H64A 1S4YB 3MJKA 1REUA 4GLNE 4EDXV 1AOCA 1B8MA 1NT3A 4N1DA 4XPJA 4LXRJ 3S1BV 4EFVA 4EDWV 2ARPA 1AGQA 1BMPA 1BNDA
chains in the Genus database with same CATH superfamily
5HI4A 5AEJA 2QJBA 5HHDA 1WQ9B 4UI2B 1JPYA 2GOOA 5FV2V 4WPBA 3BMPA 4AY9B 4QCIC 1HCFA 3V6BA 4KV5A 5BPUA 1B98A 1RV6V 5BQEB 5F3BC 1M4UL 1TGJA 2BHKA 2QCQA 1KTZA 3BK3A 1FZVA 2VPFA 3BUKA 3S1KV 4EC7A 3IJ2A 1PDGA 3JVFA 1HRPA 1XWDA 2QJ9A 1TGKA 5FV1V 1TFGA 4HR9A 4X1JA 1KLAA 3E07A 5JZ7A 3B4VA 1E9JA 1FL7B 2GH0C 1NYSB 4UHZA 3V2AA 4ZBNA 1MJVA 1BTGA 1SGFB 3EVSB 1KATW 1HCNA 2ASKA 2R52A 4UI1A 1KLCA 2R53A 2XV7A 1WQ8A 1FLTV 1ZKZA 5BQ8A 1QFWA 1BETA 1BJ1V 3EO1C 4YCIC 2FJHV 4BV4L 1B8MB 2H62A 4EAXA 2QJAA 3RJRA 1WWWV 4GLSE 4HQXA 4MIDA 1BNDB 1ES7A 1TZHV 3SEKB 4HQUA 5HI5A 1MKGA 2IFGE 1QTYR 1DZ7A 2KD3A 2V5EB 5HI3A 2B0UA 1TZIV 3FUBB 2X1WA 4HSAA 1M4UA 5HHVA 2VWEA 3QB4A 5HK5E 1REWA 4AY9A 1LXIA 4MQWA 4KXZA 2PJYA 5E4GA 1WAQA 5BQEA 3QTKA 2QCWA 1B8KA 4UHYA 3MJGA 1CZ8V 1LX5A 2P6AA 2VXSA 3BDYV 4FAOA 3KFDA 1HRPB 1NYUB 1VPFA 1XWDB 3P9WA 4YCGC 5BQBA 2ARVA 3HH2A 2FJGV 2C7WA 5BQCA 4KZNA 1FL7A 2GYZA 1WQ9A 1HCNB 2XACA 4MQWB 5HHCA 2X1XE 4QHUC 5HK5A 2TGIA 5F3HI 4ZFFC 4MPLA 4QAFC 4LXSJ 5BQ8B 2GYRA 4UI0A 1SG1A 1QFWB 5BQ8D 1HD4A 2GNNA 1MKKA 2QR0C 5HHXA 1VPPV 2H64A 1S4YB 3MJKA 1REUA 4GLNE 4EDXV 1AOCA 1B8MA 1NT3A 4N1DA 4XPJA 4LXRJ 3S1BV 4EFVA 4EDWV 2ARPA 1AGQA 1BMPA 1BNDA
chains in the Genus database with same CATH topology
5HI4A 5AEJA 2QJBA 5HHDA 1WQ9B 4UI2B 1JPYA 2GOOA 5FV2V 4WPBA 3BMPA 4AY9B 4QCIC 1HCFA 3V6BA 4KV5A 5BPUA 1B98A 1RV6V 5BQEB 5F3BC 1M4UL 1TGJA 2BHKA 2QCQA 1KTZA 3BK3A 1FZVA 2VPFA 3BUKA 3S1KV 4EC7A 3IJ2A 1PDGA 3JVFA 1HRPA 1XWDA 2QJ9A 1TGKA 5FV1V 1TFGA 4HR9A 4X1JA 1KLAA 3E07A 5JZ7A 3B4VA 1E9JA 1FL7B 2GH0C 1NYSB 4UHZA 3V2AA 4ZBNA 1MJVA 1BTGA 1SGFB 3EVSB 1KATW 1HCNA 2ASKA 2R52A 4UI1A 1KLCA 2R53A 2XV7A 1WQ8A 1FLTV 1ZKZA 5BQ8A 1QFWA 1BETA 1BJ1V 3EO1C 4YCIC 2FJHV 4BV4L 1B8MB 2H62A 4EAXA 2QJAA 3RJRA 1WWWV 4GLSE 4HQXA 4MIDA 1BNDB 1ES7A 1TZHV 3SEKB 4HQUA 5HI5A 1MKGA 2IFGE 1QTYR 1DZ7A 2KD3A 2V5EB 5HI3A 2B0UA 1TZIV 3FUBB 2X1WA 4HSAA 1M4UA 5HHVA 2VWEA 3QB4A 5HK5E 1REWA 4AY9A 1LXIA 4MQWA 4KXZA 2PJYA 5E4GA 1WAQA 5BQEA 3QTKA 2QCWA 1B8KA 4UHYA 3MJGA 1CZ8V 1LX5A 2P6AA 2VXSA 3BDYV 4FAOA 3KFDA 1HRPB 1NYUB 1VPFA 1XWDB 3P9WA 4YCGC 5BQBA 2ARVA 3HH2A 2FJGV 2C7WA 5BQCA 4KZNA 1FL7A 2GYZA 1WQ9A 1HCNB 2XACA 4MQWB 5HHCA 2X1XE 4QHUC 5HK5A 2TGIA 5F3HI 4ZFFC 4MPLA 4QAFC 4LXSJ 5BQ8B 2GYRA 4UI0A 1SG1A 1QFWB 5BQ8D 1HD4A 2GNNA 1MKKA 2QR0C 5HHXA 1VPPV 2H64A 1S4YB 3MJKA 1REUA 4GLNE 4EDXV 1AOCA 1B8MA 1NT3A 4N1DA 4XPJA 4LXRJ 3S1BV 4EFVA 4EDWV 2ARPA 1AGQA 1BMPA 1BNDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HI4 A;  5AEJ A;  2QJB A;  5HHD A;  1WQ9 B;  4UI2 B;  1JPY A;  2GOO A;  5FV2 V;  4WPB A;  3BMP A;  4AY9 B;  4QCI C;  1HCF A;  3V6B A;  4KV5 A;  5BPU A;  1B98 A;  1RV6 V;  5BQE B;  5F3B C;  1M4U L;  1TGJ A;  2BHK A;  2QCQ A;  1KTZ A;  3BK3 A;  1FZV A;  2VPF A;  3BUK A;  3S1K V;  4EC7 A;  3IJ2 A;  1PDG A;  3JVF A;  1HRP A;  1XWD A;  2QJ9 A;  1TGK A;  5FV1 V;  1TFG A;  4HR9 A;  4X1J A;  1KLA A;  3E07 A;  5JZ7 A;  3B4V A;  1E9J A;  1FL7 B;  2GH0 C;  1NYS B;  4UHZ A;  3V2A A;  4ZBN A;  1MJV A;  1BTG A;  1SGF B;  3EVS B;  1KAT W;  1HCN A;  2ASK A;  2R52 A;  4UI1 A;  1KLC A;  2R53 A;  2XV7 A;  1WQ8 A;  1FLT V;  1ZKZ A;  5BQ8 A;  1QFW A;  1BET A;  1BJ1 V;  3EO1 C;  4YCI C;  2FJH V;  4BV4 L;  1B8M B;  2H62 A;  4EAX A;  2QJA A;  3RJR A;  1WWW V;  4GLS E;  4HQX A;  4MID A;  1BND B;  1ES7 A;  1TZH V;  3SEK B;  4HQU A;  5HI5 A;  1MKG A;  2IFG E;  1QTY R;  1DZ7 A;  2KD3 A;  2V5E B;  5HI3 A;  2B0U A;  1TZI V;  3FUB B;  2X1W A;  4HSA A;  1M4U A;  5HHV A;  2VWE A;  3QB4 A;  5HK5 E;  1REW A;  4AY9 A;  1LXI A;  4MQW A;  4KXZ A;  2PJY A;  5E4G A;  1WAQ A;  5BQE A;  3QTK A;  2QCW A;  1B8K A;  4UHY A;  3MJG A;  1CZ8 V;  1LX5 A;  2P6A A;  2VXS A;  3BDY V;  4FAO A;  3KFD A;  1HRP B;  1NYU B;  1VPF A;  1XWD B;  3P9W A;  4YCG C;  5BQB A;  2ARV A;  3HH2 A;  2FJG V;  2C7W A;  5BQC A;  4KZN A;  1FL7 A;  2GYZ A;  1WQ9 A;  1HCN B;  2XAC A;  4MQW B;  5HHC A;  2X1X E;  4QHU C;  5HK5 A;  2TGI A;  5F3H I;  4ZFF C;  4MPL A;  4QAF C;  4LXS J;  5BQ8 B;  2GYR A;  4UI0 A;  1SG1 A;  1QFW B;  5BQ8 D;  1HD4 A;  2GNN A;  1MKK A;  2QR0 C;  5HHX A;  1VPP V;  2H64 A;  1S4Y B;  3MJK A;  1REU A;  4GLN E;  4EDX V;  1AOC A;  1B8M A;  1NT3 A;  4N1D A;  4XPJ A;  4LXR J;  3S1B V;  4EFV A;  4EDW V;  2ARP A;  1AGQ A;  1BMP A;  1BND A; 
#chains in the Genus database with same CATH topology
 5HI4 A;  5AEJ A;  2QJB A;  5HHD A;  1WQ9 B;  4UI2 B;  1JPY A;  2GOO A;  5FV2 V;  4WPB A;  3BMP A;  4AY9 B;  4QCI C;  1HCF A;  3V6B A;  4KV5 A;  5BPU A;  1B98 A;  1RV6 V;  5BQE B;  5F3B C;  1M4U L;  1TGJ A;  2BHK A;  2QCQ A;  1KTZ A;  3BK3 A;  1FZV A;  2VPF A;  3BUK A;  3S1K V;  4EC7 A;  3IJ2 A;  1PDG A;  3JVF A;  1HRP A;  1XWD A;  2QJ9 A;  1TGK A;  5FV1 V;  1TFG A;  4HR9 A;  4X1J A;  1KLA A;  3E07 A;  5JZ7 A;  3B4V A;  1E9J A;  1FL7 B;  2GH0 C;  1NYS B;  4UHZ A;  3V2A A;  4ZBN A;  1MJV A;  1BTG A;  1SGF B;  3EVS B;  1KAT W;  1HCN A;  2ASK A;  2R52 A;  4UI1 A;  1KLC A;  2R53 A;  2XV7 A;  1WQ8 A;  1FLT V;  1ZKZ A;  5BQ8 A;  1QFW A;  1BET A;  1BJ1 V;  3EO1 C;  4YCI C;  2FJH V;  4BV4 L;  1B8M B;  2H62 A;  4EAX A;  2QJA A;  3RJR A;  1WWW V;  4GLS E;  4HQX A;  4MID A;  1BND B;  1ES7 A;  1TZH V;  3SEK B;  4HQU A;  5HI5 A;  1MKG A;  2IFG E;  1QTY R;  1DZ7 A;  2KD3 A;  2V5E B;  5HI3 A;  2B0U A;  1TZI V;  3FUB B;  2X1W A;  4HSA A;  1M4U A;  5HHV A;  2VWE A;  3QB4 A;  5HK5 E;  1REW A;  4AY9 A;  1LXI A;  4MQW A;  4KXZ A;  2PJY A;  5E4G A;  1WAQ A;  5BQE A;  3QTK A;  2QCW A;  1B8K A;  4UHY A;  3MJG A;  1CZ8 V;  1LX5 A;  2P6A A;  2VXS A;  3BDY V;  4FAO A;  3KFD A;  1HRP B;  1NYU B;  1VPF A;  1XWD B;  3P9W A;  4YCG C;  5BQB A;  2ARV A;  3HH2 A;  2FJG V;  2C7W A;  5BQC A;  4KZN A;  1FL7 A;  2GYZ A;  1WQ9 A;  1HCN B;  2XAC A;  4MQW B;  5HHC A;  2X1X E;  4QHU C;  5HK5 A;  2TGI A;  5F3H I;  4ZFF C;  4MPL A;  4QAF C;  4LXS J;  5BQ8 B;  2GYR A;  4UI0 A;  1SG1 A;  1QFW B;  5BQ8 D;  1HD4 A;  2GNN A;  1MKK A;  2QR0 C;  5HHX A;  1VPP V;  2H64 A;  1S4Y B;  3MJK A;  1REU A;  4GLN E;  4EDX V;  1AOC A;  1B8M A;  1NT3 A;  4N1D A;  4XPJ A;  4LXR J;  3S1B V;  4EFV A;  4EDW V;  2ARP A;  1AGQ A;  1BMP A;  1BND A; 
#chains in the Genus database with same CATH homology
 5HI4 A;  5AEJ A;  2QJB A;  5HHD A;  1WQ9 B;  4UI2 B;  1JPY A;  2GOO A;  5FV2 V;  4WPB A;  3BMP A;  4AY9 B;  4QCI C;  1HCF A;  3V6B A;  4KV5 A;  5BPU A;  1B98 A;  1RV6 V;  5BQE B;  5F3B C;  1M4U L;  1TGJ A;  2BHK A;  2QCQ A;  1KTZ A;  3BK3 A;  1FZV A;  2VPF A;  3BUK A;  3S1K V;  4EC7 A;  3IJ2 A;  1PDG A;  3JVF A;  1HRP A;  1XWD A;  2QJ9 A;  1TGK A;  5FV1 V;  1TFG A;  4HR9 A;  4X1J A;  1KLA A;  3E07 A;  5JZ7 A;  3B4V A;  1E9J A;  1FL7 B;  2GH0 C;  1NYS B;  4UHZ A;  3V2A A;  4ZBN A;  1MJV A;  1BTG A;  1SGF B;  3EVS B;  1KAT W;  1HCN A;  2ASK A;  2R52 A;  4UI1 A;  1KLC A;  2R53 A;  2XV7 A;  1WQ8 A;  1FLT V;  1ZKZ A;  5BQ8 A;  1QFW A;  1BET A;  1BJ1 V;  3EO1 C;  4YCI C;  2FJH V;  4BV4 L;  1B8M B;  2H62 A;  4EAX A;  2QJA A;  3RJR A;  1WWW V;  4GLS E;  4HQX A;  4MID A;  1BND B;  1ES7 A;  1TZH V;  3SEK B;  4HQU A;  5HI5 A;  1MKG A;  2IFG E;  1QTY R;  1DZ7 A;  2KD3 A;  2V5E B;  5HI3 A;  2B0U A;  1TZI V;  3FUB B;  2X1W A;  4HSA A;  1M4U A;  5HHV A;  2VWE A;  3QB4 A;  5HK5 E;  1REW A;  4AY9 A;  1LXI A;  4MQW A;  4KXZ A;  2PJY A;  5E4G A;  1WAQ A;  5BQE A;  3QTK A;  2QCW A;  1B8K A;  4UHY A;  3MJG A;  1CZ8 V;  1LX5 A;  2P6A A;  2VXS A;  3BDY V;  4FAO A;  3KFD A;  1HRP B;  1NYU B;  1VPF A;  1XWD B;  3P9W A;  4YCG C;  5BQB A;  2ARV A;  3HH2 A;  2FJG V;  2C7W A;  5BQC A;  4KZN A;  1FL7 A;  2GYZ A;  1WQ9 A;  1HCN B;  2XAC A;  4MQW B;  5HHC A;  2X1X E;  4QHU C;  5HK5 A;  2TGI A;  5F3H I;  4ZFF C;  4MPL A;  4QAF C;  4LXS J;  5BQ8 B;  2GYR A;  4UI0 A;  1SG1 A;  1QFW B;  5BQ8 D;  1HD4 A;  2GNN A;  1MKK A;  2QR0 C;  5HHX A;  1VPP V;  2H64 A;  1S4Y B;  3MJK A;  1REU A;  4GLN E;  4EDX V;  1AOC A;  1B8M A;  1NT3 A;  4N1D A;  4XPJ A;  4LXR J;  3S1B V;  4EFV A;  4EDW V;  2ARP A;  1AGQ A;  1BMP A;  1BND A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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