1AOCA

Japanese horseshoe crab coagulogen
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
Knots found
sequence length
175
structure length
175
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
pubmed rcsb
molecule tags Coagulation factor
molecule keywords COAGULOGEN
total genus 40
structure length 175
sequence length 175
chains with identical sequence B
other databases KnotProt 2.0: K
ec nomenclature
pdb deposition date 1996-11-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02035 Coagulin Coagulin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
2X1WA 4QAFC 4KZNA 1BMPA 1HCNA 4X1JA 1WQ9A 5AEJA 3E07A 1FL7A 5FV1V 5HHVA 2IFGE 4UI2B 1ES7A 1VPPV 3KFDA 1WAQA 2QR0C 4EC7A 5FV2V 1KLAA 3S1BV 2GYZA 4EDWV 5HK5A 3BDYV 3BK3A 4EDXV 4WPBA 1B8MA 1TZHV 4ZFFC 3V6BA 1S4YB 2ARPA 3MJKA 1BTGA 2GNNA 1TFGA 2KD3A 2FJHV 4HQUA 2QJ9A 2QCQA 4XPJA 4EAXA 2C7WA 1QFWB 1MJVA 1BETA 1MKKA 4HR9A 4N1DA 2QJBA 5F3HI 1KTZA 1NYUB 2H62A 2XV7A 1AGQA 1KATW 1KLCA 2QJAA 3MJGA 4MPLA 1HRPB 1CZ8V 3V2AA 2H64A 3QB4A 1WQ8A 1NYSB 4MIDA 2VPFA 3P9WA 1REUA 4LXSJ 5BQCA 5HI4A 1JPYA 1QFWA 1M4UA 3EO1C 4UI0A 5BQ8B 1LXIA 4AY9B 1XWDB 4GLSE 4BV4L 3EVSB 5HHCA 5HI3A 3SEKB 1REWA 2VXSA 1HRPA 1ZKZA 1BJ1V 4HSAA 1SG1A 1WWWV 3JVFA 4EFVA 5BPUA 4GLNE 1TZIV 3RJRA 1SGFB 2BHKA 4FAOA 1B8KA 2QCWA 3QTKA 1HCNB 1DZ7A 1LX5A 5BQ8A 4ZBNA 1FL7B 1QTYR 2X1XE 4AY9A 5HK5E 3S1KV 1XWDA 2R52A 4QCIC 3BUKA 2ASKA 5HHDA 1RV6V 2V5EB 1AOCA 4HQXA 1FLTV 3BMPA 3FUBB 2GH0C 2P6AA 5JZ7A 2GYRA 1HCFA 1BNDB 2PJYA 2VWEA 5BQ8D 4UHYA 2TGIA 4LXRJ 5HI5A 1B8MB 5BQEB 3B4VA 1HD4A 1FZVA 4MQWB 1VPFA 3IJ2A 5E4GA 5HHXA 4QHUC 1MKGA 1B98A 1NT3A 1E9JA 5BQBA 1PDGA 1WQ9B 4YCGC 1BNDA 1TGKA 2B0UA 2GOOA 4KXZA 4UHZA 1M4UL 1TGJA 5BQEA 4UI1A 4KV5A 2ARVA 3HH2A 4MQWA 2R53A 5F3BC 4YCIC 2XACA 2FJGV
chains in the Genus database with same CATH superfamily
2X1WA 4QAFC 4KZNA 1BMPA 1HCNA 4X1JA 1WQ9A 5AEJA 3E07A 1FL7A 5FV1V 5HHVA 2IFGE 4UI2B 1ES7A 1VPPV 3KFDA 1WAQA 2QR0C 4EC7A 5FV2V 1KLAA 3S1BV 2GYZA 4EDWV 5HK5A 3BDYV 3BK3A 4EDXV 4WPBA 1B8MA 1TZHV 4ZFFC 3V6BA 1S4YB 2ARPA 3MJKA 1BTGA 2GNNA 1TFGA 2KD3A 2FJHV 4HQUA 2QJ9A 2QCQA 4XPJA 4EAXA 2C7WA 1QFWB 1MJVA 1BETA 1MKKA 4HR9A 4N1DA 2QJBA 5F3HI 1KTZA 1NYUB 2H62A 2XV7A 1AGQA 1KATW 1KLCA 2QJAA 3MJGA 4MPLA 1HRPB 1CZ8V 3V2AA 2H64A 3QB4A 1WQ8A 1NYSB 4MIDA 2VPFA 3P9WA 1REUA 4LXSJ 5BQCA 5HI4A 1JPYA 1QFWA 1M4UA 3EO1C 4UI0A 5BQ8B 1LXIA 4AY9B 1XWDB 4GLSE 4BV4L 3EVSB 5HHCA 5HI3A 3SEKB 1REWA 2VXSA 1HRPA 1ZKZA 1BJ1V 4HSAA 1SG1A 1WWWV 3JVFA 4EFVA 5BPUA 4GLNE 1TZIV 3RJRA 1SGFB 2BHKA 4FAOA 1B8KA 2QCWA 3QTKA 1HCNB 1DZ7A 1LX5A 5BQ8A 4ZBNA 1FL7B 1QTYR 2X1XE 4AY9A 5HK5E 3S1KV 1XWDA 2R52A 4QCIC 3BUKA 2ASKA 5HHDA 1RV6V 2V5EB 1AOCA 4HQXA 1FLTV 3BMPA 3FUBB 2GH0C 2P6AA 5JZ7A 2GYRA 1HCFA 1BNDB 2PJYA 2VWEA 5BQ8D 4UHYA 2TGIA 4LXRJ 5HI5A 1B8MB 5BQEB 3B4VA 1HD4A 1FZVA 4MQWB 1VPFA 3IJ2A 5E4GA 5HHXA 4QHUC 1MKGA 1B98A 1NT3A 1E9JA 5BQBA 1PDGA 1WQ9B 4YCGC 1BNDA 1TGKA 2B0UA 2GOOA 4KXZA 4UHZA 1M4UL 1TGJA 5BQEA 4UI1A 4KV5A 2ARVA 3HH2A 4MQWA 2R53A 5F3BC 4YCIC 2XACA 2FJGV
chains in the Genus database with same CATH topology
2X1WA 4QAFC 4KZNA 1BMPA 1HCNA 4X1JA 1WQ9A 5AEJA 3E07A 1FL7A 5FV1V 5HHVA 2IFGE 4UI2B 1ES7A 1VPPV 3KFDA 1WAQA 2QR0C 4EC7A 5FV2V 1KLAA 3S1BV 2GYZA 4EDWV 5HK5A 3BDYV 3BK3A 4EDXV 4WPBA 1B8MA 1TZHV 4ZFFC 3V6BA 1S4YB 2ARPA 3MJKA 1BTGA 2GNNA 1TFGA 2KD3A 2FJHV 4HQUA 2QJ9A 2QCQA 4XPJA 4EAXA 2C7WA 1QFWB 1MJVA 1BETA 1MKKA 4HR9A 4N1DA 2QJBA 5F3HI 1KTZA 1NYUB 2H62A 2XV7A 1AGQA 1KATW 1KLCA 2QJAA 3MJGA 4MPLA 1HRPB 1CZ8V 3V2AA 2H64A 3QB4A 1WQ8A 1NYSB 4MIDA 2VPFA 3P9WA 1REUA 4LXSJ 5BQCA 5HI4A 1JPYA 1QFWA 1M4UA 3EO1C 4UI0A 5BQ8B 1LXIA 4AY9B 1XWDB 4GLSE 4BV4L 3EVSB 5HHCA 5HI3A 3SEKB 1REWA 2VXSA 1HRPA 1ZKZA 1BJ1V 4HSAA 1SG1A 1WWWV 3JVFA 4EFVA 5BPUA 4GLNE 1TZIV 3RJRA 1SGFB 2BHKA 4FAOA 1B8KA 2QCWA 3QTKA 1HCNB 1DZ7A 1LX5A 5BQ8A 4ZBNA 1FL7B 1QTYR 2X1XE 4AY9A 5HK5E 3S1KV 1XWDA 2R52A 4QCIC 3BUKA 2ASKA 5HHDA 1RV6V 2V5EB 1AOCA 4HQXA 1FLTV 3BMPA 3FUBB 2GH0C 2P6AA 5JZ7A 2GYRA 1HCFA 1BNDB 2PJYA 2VWEA 5BQ8D 4UHYA 2TGIA 4LXRJ 5HI5A 1B8MB 5BQEB 3B4VA 1HD4A 1FZVA 4MQWB 1VPFA 3IJ2A 5E4GA 5HHXA 4QHUC 1MKGA 1B98A 1NT3A 1E9JA 5BQBA 1PDGA 1WQ9B 4YCGC 1BNDA 1TGKA 2B0UA 2GOOA 4KXZA 4UHZA 1M4UL 1TGJA 5BQEA 4UI1A 4KV5A 2ARVA 3HH2A 4MQWA 2R53A 5F3BC 4YCIC 2XACA 2FJGV
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X1W A;  4QAF C;  4KZN A;  1BMP A;  1HCN A;  4X1J A;  1WQ9 A;  5AEJ A;  3E07 A;  1FL7 A;  5FV1 V;  5HHV A;  2IFG E;  4UI2 B;  1ES7 A;  1VPP V;  3KFD A;  1WAQ A;  2QR0 C;  4EC7 A;  5FV2 V;  1KLA A;  3S1B V;  2GYZ A;  4EDW V;  5HK5 A;  3BDY V;  3BK3 A;  4EDX V;  4WPB A;  1B8M A;  1TZH V;  4ZFF C;  3V6B A;  1S4Y B;  2ARP A;  3MJK A;  1BTG A;  2GNN A;  1TFG A;  2KD3 A;  2FJH V;  4HQU A;  2QJ9 A;  2QCQ A;  4XPJ A;  4EAX A;  2C7W A;  1QFW B;  1MJV A;  1BET A;  1MKK A;  4HR9 A;  4N1D A;  2QJB A;  5F3H I;  1KTZ A;  1NYU B;  2H62 A;  2XV7 A;  1AGQ A;  1KAT W;  1KLC A;  2QJA A;  3MJG A;  4MPL A;  1HRP B;  1CZ8 V;  3V2A A;  2H64 A;  3QB4 A;  1WQ8 A;  1NYS B;  4MID A;  2VPF A;  3P9W A;  1REU A;  4LXS J;  5BQC A;  5HI4 A;  1JPY A;  1QFW A;  1M4U A;  3EO1 C;  4UI0 A;  5BQ8 B;  1LXI A;  4AY9 B;  1XWD B;  4GLS E;  4BV4 L;  3EVS B;  5HHC A;  5HI3 A;  3SEK B;  1REW A;  2VXS A;  1HRP A;  1ZKZ A;  1BJ1 V;  4HSA A;  1SG1 A;  1WWW V;  3JVF A;  4EFV A;  5BPU A;  4GLN E;  1TZI V;  3RJR A;  1SGF B;  2BHK A;  4FAO A;  1B8K A;  2QCW A;  3QTK A;  1HCN B;  1DZ7 A;  1LX5 A;  5BQ8 A;  4ZBN A;  1FL7 B;  1QTY R;  2X1X E;  4AY9 A;  5HK5 E;  3S1K V;  1XWD A;  2R52 A;  4QCI C;  3BUK A;  2ASK A;  5HHD A;  1RV6 V;  2V5E B;  1AOC A;  4HQX A;  1FLT V;  3BMP A;  3FUB B;  2GH0 C;  2P6A A;  5JZ7 A;  2GYR A;  1HCF A;  1BND B;  2PJY A;  2VWE A;  5BQ8 D;  4UHY A;  2TGI A;  4LXR J;  5HI5 A;  1B8M B;  5BQE B;  3B4V A;  1HD4 A;  1FZV A;  4MQW B;  1VPF A;  3IJ2 A;  5E4G A;  5HHX A;  4QHU C;  1MKG A;  1B98 A;  1NT3 A;  1E9J A;  5BQB A;  1PDG A;  1WQ9 B;  4YCG C;  1BND A;  1TGK A;  2B0U A;  2GOO A;  4KXZ A;  4UHZ A;  1M4U L;  1TGJ A;  5BQE A;  4UI1 A;  4KV5 A;  2ARV A;  3HH2 A;  4MQW A;  2R53 A;  5F3B C;  4YCI C;  2XAC A;  2FJG V; 
#chains in the Genus database with same CATH topology
 2X1W A;  4QAF C;  4KZN A;  1BMP A;  1HCN A;  4X1J A;  1WQ9 A;  5AEJ A;  3E07 A;  1FL7 A;  5FV1 V;  5HHV A;  2IFG E;  4UI2 B;  1ES7 A;  1VPP V;  3KFD A;  1WAQ A;  2QR0 C;  4EC7 A;  5FV2 V;  1KLA A;  3S1B V;  2GYZ A;  4EDW V;  5HK5 A;  3BDY V;  3BK3 A;  4EDX V;  4WPB A;  1B8M A;  1TZH V;  4ZFF C;  3V6B A;  1S4Y B;  2ARP A;  3MJK A;  1BTG A;  2GNN A;  1TFG A;  2KD3 A;  2FJH V;  4HQU A;  2QJ9 A;  2QCQ A;  4XPJ A;  4EAX A;  2C7W A;  1QFW B;  1MJV A;  1BET A;  1MKK A;  4HR9 A;  4N1D A;  2QJB A;  5F3H I;  1KTZ A;  1NYU B;  2H62 A;  2XV7 A;  1AGQ A;  1KAT W;  1KLC A;  2QJA A;  3MJG A;  4MPL A;  1HRP B;  1CZ8 V;  3V2A A;  2H64 A;  3QB4 A;  1WQ8 A;  1NYS B;  4MID A;  2VPF A;  3P9W A;  1REU A;  4LXS J;  5BQC A;  5HI4 A;  1JPY A;  1QFW A;  1M4U A;  3EO1 C;  4UI0 A;  5BQ8 B;  1LXI A;  4AY9 B;  1XWD B;  4GLS E;  4BV4 L;  3EVS B;  5HHC A;  5HI3 A;  3SEK B;  1REW A;  2VXS A;  1HRP A;  1ZKZ A;  1BJ1 V;  4HSA A;  1SG1 A;  1WWW V;  3JVF A;  4EFV A;  5BPU A;  4GLN E;  1TZI V;  3RJR A;  1SGF B;  2BHK A;  4FAO A;  1B8K A;  2QCW A;  3QTK A;  1HCN B;  1DZ7 A;  1LX5 A;  5BQ8 A;  4ZBN A;  1FL7 B;  1QTY R;  2X1X E;  4AY9 A;  5HK5 E;  3S1K V;  1XWD A;  2R52 A;  4QCI C;  3BUK A;  2ASK A;  5HHD A;  1RV6 V;  2V5E B;  1AOC A;  4HQX A;  1FLT V;  3BMP A;  3FUB B;  2GH0 C;  2P6A A;  5JZ7 A;  2GYR A;  1HCF A;  1BND B;  2PJY A;  2VWE A;  5BQ8 D;  4UHY A;  2TGI A;  4LXR J;  5HI5 A;  1B8M B;  5BQE B;  3B4V A;  1HD4 A;  1FZV A;  4MQW B;  1VPF A;  3IJ2 A;  5E4G A;  5HHX A;  4QHU C;  1MKG A;  1B98 A;  1NT3 A;  1E9J A;  5BQB A;  1PDG A;  1WQ9 B;  4YCG C;  1BND A;  1TGK A;  2B0U A;  2GOO A;  4KXZ A;  4UHZ A;  1M4U L;  1TGJ A;  5BQE A;  4UI1 A;  4KV5 A;  2ARV A;  3HH2 A;  4MQW A;  2R53 A;  5F3B C;  4YCI C;  2XAC A;  2FJG V; 
#chains in the Genus database with same CATH homology
 2X1W A;  4QAF C;  4KZN A;  1BMP A;  1HCN A;  4X1J A;  1WQ9 A;  5AEJ A;  3E07 A;  1FL7 A;  5FV1 V;  5HHV A;  2IFG E;  4UI2 B;  1ES7 A;  1VPP V;  3KFD A;  1WAQ A;  2QR0 C;  4EC7 A;  5FV2 V;  1KLA A;  3S1B V;  2GYZ A;  4EDW V;  5HK5 A;  3BDY V;  3BK3 A;  4EDX V;  4WPB A;  1B8M A;  1TZH V;  4ZFF C;  3V6B A;  1S4Y B;  2ARP A;  3MJK A;  1BTG A;  2GNN A;  1TFG A;  2KD3 A;  2FJH V;  4HQU A;  2QJ9 A;  2QCQ A;  4XPJ A;  4EAX A;  2C7W A;  1QFW B;  1MJV A;  1BET A;  1MKK A;  4HR9 A;  4N1D A;  2QJB A;  5F3H I;  1KTZ A;  1NYU B;  2H62 A;  2XV7 A;  1AGQ A;  1KAT W;  1KLC A;  2QJA A;  3MJG A;  4MPL A;  1HRP B;  1CZ8 V;  3V2A A;  2H64 A;  3QB4 A;  1WQ8 A;  1NYS B;  4MID A;  2VPF A;  3P9W A;  1REU A;  4LXS J;  5BQC A;  5HI4 A;  1JPY A;  1QFW A;  1M4U A;  3EO1 C;  4UI0 A;  5BQ8 B;  1LXI A;  4AY9 B;  1XWD B;  4GLS E;  4BV4 L;  3EVS B;  5HHC A;  5HI3 A;  3SEK B;  1REW A;  2VXS A;  1HRP A;  1ZKZ A;  1BJ1 V;  4HSA A;  1SG1 A;  1WWW V;  3JVF A;  4EFV A;  5BPU A;  4GLN E;  1TZI V;  3RJR A;  1SGF B;  2BHK A;  4FAO A;  1B8K A;  2QCW A;  3QTK A;  1HCN B;  1DZ7 A;  1LX5 A;  5BQ8 A;  4ZBN A;  1FL7 B;  1QTY R;  2X1X E;  4AY9 A;  5HK5 E;  3S1K V;  1XWD A;  2R52 A;  4QCI C;  3BUK A;  2ASK A;  5HHD A;  1RV6 V;  2V5E B;  1AOC A;  4HQX A;  1FLT V;  3BMP A;  3FUB B;  2GH0 C;  2P6A A;  5JZ7 A;  2GYR A;  1HCF A;  1BND B;  2PJY A;  2VWE A;  5BQ8 D;  4UHY A;  2TGI A;  4LXR J;  5HI5 A;  1B8M B;  5BQE B;  3B4V A;  1HD4 A;  1FZV A;  4MQW B;  1VPF A;  3IJ2 A;  5E4G A;  5HHX A;  4QHU C;  1MKG A;  1B98 A;  1NT3 A;  1E9J A;  5BQB A;  1PDG A;  1WQ9 B;  4YCG C;  1BND A;  1TGK A;  2B0U A;  2GOO A;  4KXZ A;  4UHZ A;  1M4U L;  1TGJ A;  5BQE A;  4UI1 A;  4KV5 A;  2ARV A;  3HH2 A;  4MQW A;  2R53 A;  5F3B C;  4YCI C;  2XAC A;  2FJG V; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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