1AOCA

Japanese horseshoe crab coagulogen
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
Knots found
sequence length
175
structure length
175
Chain Sequence
ADTNAPICLCDEPGVLGRTQIVTTEIKDKIEKAVEAVAQESGVSGRGFSIFSHHPVFRECGKYECRTVRPEHSRCYNFPPFTHFKSECPVSTRDCEPVFGYTVAGEFRVIVQAPRAGFRQCVWQHKCRFGSNSCGYNGRCTQQRSVVRLVTYNLEKDGFLCESFRTCCGCPCRSF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a coagulogen, the clotting protein from horseshoe crab: a structural homologue of nerve growth factor.
pubmed rcsb
molecule tags Coagulation factor
molecule keywords COAGULOGEN
total genus 40
structure length 175
sequence length 175
chains with identical sequence B
other databases KnotProt 2.0: K
ec nomenclature
pdb deposition date 1996-11-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02035 Coagulin Coagulin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1aocA00
2BHKA 2GYRA 1ES7A 2GYZA 1BNDA 1KATW 4GLNE 3P9WA 4EDWV 1TGKA 5BQ8D 1TFGA 2QR0C 3BMPA 4ZBNA 1B8MA 4GLSE 1BMPA 3EVSB 5BQEA 1PDGA 2QJ9A 5HK5A 1BTGA 4UHZA 1XWDA 4XPJA 3KFDA 2QJBA 2QCWA 4ZFFC 1B8KA 3SEKB 1NT3A 4LXRJ 2GOOA 3S1BV 4EAXA 4QCIC 2VWEA 1KLAA 1M4UA 2PJYA 1TZIV 3RJRA 5HI5A 3MJKA 3FUBB 3IJ2A 4KXZA 4N1DA 1REUA 1E9JA 1WQ9B 4MIDA 5BQ8A 2TGIA 1FL7A 1LXIA 1BNDB 2V5EB 2GNNA 4UI1A 1HCNA 1KTZA 2H64A 5BPUA 3V2AA 5E4GA 2XV7A 4YCGC 1B8MB 5BQEB 2IFGE 1TZHV 1DZ7A 1NYSB 1XWDB 3B4VA 2XACA 3BK3A 1HCFA 4MPLA 4EFVA 5FV1V 5FV2V 1MKKA 2X1WA 4EDXV 2H62A 3E07A 3EO1C 4HR9A 2ARVA 1JPYA 5HI4A 5HHXA 5HHDA 1VPPV 1QTYR 5HHVA 4X1JA 5HI3A 1VPFA 4AY9A 5BQBA 4HQUA 1TGJA 1M4UL 1BETA 1MKGA 3JVFA 5BQ8B 4BV4L 1FL7B 4FAOA 1HD4A 1HRPA 5F3HI 4HQXA 1LX5A 2QJAA 4EC7A 4MQWA 1CZ8V 5HHCA 1QFWA 1HCNB 3HH2A 1B98A 1KLCA 2P6AA 2ASKA 1WWWV 1REWA 4QHUC 1MJVA 2ARPA 5JZ7A 4QAFC 4UI0A 1AOCA 2R53A 1SG1A 5AEJA 2C7WA 1AGQA 2GH0C 1S4YB 1FZVA 3BDYV 1ZKZA 2VPFA 1RV6V 3BUKA 4UHYA 1WAQA 4LXSJ 2FJHV 4KV5A 1WQ8A 1FLTV 5BQCA 2X1XE 2B0UA 4KZNA 3MJGA 4AY9B 1BJ1V 1NYUB 1SGFB 2R52A 4HSAA 3S1KV 1HRPB 3QTKA 4UI2B 2KD3A 2VXSA 4MQWB 4YCIC 1QFWB 2FJGV 4WPBA 5HK5E 5F3BC 2QCQA 3V6BA 1WQ9A 3QB4A
chains in the Genus database with same CATH superfamily
2BHKA 2GYRA 1ES7A 2GYZA 1BNDA 1KATW 4GLNE 3P9WA 4EDWV 1TGKA 5BQ8D 1TFGA 2QR0C 3BMPA 4ZBNA 1B8MA 4GLSE 1BMPA 3EVSB 5BQEA 1PDGA 2QJ9A 5HK5A 1BTGA 4UHZA 1XWDA 4XPJA 3KFDA 2QJBA 2QCWA 4ZFFC 1B8KA 3SEKB 1NT3A 4LXRJ 2GOOA 3S1BV 4EAXA 4QCIC 2VWEA 1KLAA 1M4UA 2PJYA 1TZIV 3RJRA 5HI5A 3MJKA 3FUBB 3IJ2A 4KXZA 4N1DA 1REUA 1E9JA 1WQ9B 4MIDA 5BQ8A 2TGIA 1FL7A 1LXIA 1BNDB 2V5EB 2GNNA 4UI1A 1HCNA 1KTZA 2H64A 5BPUA 3V2AA 5E4GA 2XV7A 4YCGC 1B8MB 5BQEB 2IFGE 1TZHV 1DZ7A 1NYSB 1XWDB 3B4VA 2XACA 3BK3A 1HCFA 4MPLA 4EFVA 5FV1V 5FV2V 1MKKA 2X1WA 4EDXV 2H62A 3E07A 3EO1C 4HR9A 2ARVA 1JPYA 5HI4A 5HHXA 5HHDA 1VPPV 1QTYR 5HHVA 4X1JA 5HI3A 1VPFA 4AY9A 5BQBA 4HQUA 1TGJA 1M4UL 1BETA 1MKGA 3JVFA 5BQ8B 4BV4L 1FL7B 4FAOA 1HD4A 1HRPA 5F3HI 4HQXA 1LX5A 2QJAA 4EC7A 4MQWA 1CZ8V 5HHCA 1QFWA 1HCNB 3HH2A 1B98A 1KLCA 2P6AA 2ASKA 1WWWV 1REWA 4QHUC 1MJVA 2ARPA 5JZ7A 4QAFC 4UI0A 1AOCA 2R53A 1SG1A 5AEJA 2C7WA 1AGQA 2GH0C 1S4YB 1FZVA 3BDYV 1ZKZA 2VPFA 1RV6V 3BUKA 4UHYA 1WAQA 4LXSJ 2FJHV 4KV5A 1WQ8A 1FLTV 5BQCA 2X1XE 2B0UA 4KZNA 3MJGA 4AY9B 1BJ1V 1NYUB 1SGFB 2R52A 4HSAA 3S1KV 1HRPB 3QTKA 4UI2B 2KD3A 2VXSA 4MQWB 4YCIC 1QFWB 2FJGV 4WPBA 5HK5E 5F3BC 2QCQA 3V6BA 1WQ9A 3QB4A
chains in the Genus database with same CATH topology
2BHKA 2GYRA 1ES7A 2GYZA 1BNDA 1KATW 4GLNE 3P9WA 4EDWV 1TGKA 5BQ8D 1TFGA 2QR0C 3BMPA 4ZBNA 1B8MA 4GLSE 1BMPA 3EVSB 5BQEA 1PDGA 2QJ9A 5HK5A 1BTGA 4UHZA 1XWDA 4XPJA 3KFDA 2QJBA 2QCWA 4ZFFC 1B8KA 3SEKB 1NT3A 4LXRJ 2GOOA 3S1BV 4EAXA 4QCIC 2VWEA 1KLAA 1M4UA 2PJYA 1TZIV 3RJRA 5HI5A 3MJKA 3FUBB 3IJ2A 4KXZA 4N1DA 1REUA 1E9JA 1WQ9B 4MIDA 5BQ8A 2TGIA 1FL7A 1LXIA 1BNDB 2V5EB 2GNNA 4UI1A 1HCNA 1KTZA 2H64A 5BPUA 3V2AA 5E4GA 2XV7A 4YCGC 1B8MB 5BQEB 2IFGE 1TZHV 1DZ7A 1NYSB 1XWDB 3B4VA 2XACA 3BK3A 1HCFA 4MPLA 4EFVA 5FV1V 5FV2V 1MKKA 2X1WA 4EDXV 2H62A 3E07A 3EO1C 4HR9A 2ARVA 1JPYA 5HI4A 5HHXA 5HHDA 1VPPV 1QTYR 5HHVA 4X1JA 5HI3A 1VPFA 4AY9A 5BQBA 4HQUA 1TGJA 1M4UL 1BETA 1MKGA 3JVFA 5BQ8B 4BV4L 1FL7B 4FAOA 1HD4A 1HRPA 5F3HI 4HQXA 1LX5A 2QJAA 4EC7A 4MQWA 1CZ8V 5HHCA 1QFWA 1HCNB 3HH2A 1B98A 1KLCA 2P6AA 2ASKA 1WWWV 1REWA 4QHUC 1MJVA 2ARPA 5JZ7A 4QAFC 4UI0A 1AOCA 2R53A 1SG1A 5AEJA 2C7WA 1AGQA 2GH0C 1S4YB 1FZVA 3BDYV 1ZKZA 2VPFA 1RV6V 3BUKA 4UHYA 1WAQA 4LXSJ 2FJHV 4KV5A 1WQ8A 1FLTV 5BQCA 2X1XE 2B0UA 4KZNA 3MJGA 4AY9B 1BJ1V 1NYUB 1SGFB 2R52A 4HSAA 3S1KV 1HRPB 3QTKA 4UI2B 2KD3A 2VXSA 4MQWB 4YCIC 1QFWB 2FJGV 4WPBA 5HK5E 5F3BC 2QCQA 3V6BA 1WQ9A 3QB4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BHK A;  2GYR A;  1ES7 A;  2GYZ A;  1BND A;  1KAT W;  4GLN E;  3P9W A;  4EDW V;  1TGK A;  5BQ8 D;  1TFG A;  2QR0 C;  3BMP A;  4ZBN A;  1B8M A;  4GLS E;  1BMP A;  3EVS B;  5BQE A;  1PDG A;  2QJ9 A;  5HK5 A;  1BTG A;  4UHZ A;  1XWD A;  4XPJ A;  3KFD A;  2QJB A;  2QCW A;  4ZFF C;  1B8K A;  3SEK B;  1NT3 A;  4LXR J;  2GOO A;  3S1B V;  4EAX A;  4QCI C;  2VWE A;  1KLA A;  1M4U A;  2PJY A;  1TZI V;  3RJR A;  5HI5 A;  3MJK A;  3FUB B;  3IJ2 A;  4KXZ A;  4N1D A;  1REU A;  1E9J A;  1WQ9 B;  4MID A;  5BQ8 A;  2TGI A;  1FL7 A;  1LXI A;  1BND B;  2V5E B;  2GNN A;  4UI1 A;  1HCN A;  1KTZ A;  2H64 A;  5BPU A;  3V2A A;  5E4G A;  2XV7 A;  4YCG C;  1B8M B;  5BQE B;  2IFG E;  1TZH V;  1DZ7 A;  1NYS B;  1XWD B;  3B4V A;  2XAC A;  3BK3 A;  1HCF A;  4MPL A;  4EFV A;  5FV1 V;  5FV2 V;  1MKK A;  2X1W A;  4EDX V;  2H62 A;  3E07 A;  3EO1 C;  4HR9 A;  2ARV A;  1JPY A;  5HI4 A;  5HHX A;  5HHD A;  1VPP V;  1QTY R;  5HHV A;  4X1J A;  5HI3 A;  1VPF A;  4AY9 A;  5BQB A;  4HQU A;  1TGJ A;  1M4U L;  1BET A;  1MKG A;  3JVF A;  5BQ8 B;  4BV4 L;  1FL7 B;  4FAO A;  1HD4 A;  1HRP A;  5F3H I;  4HQX A;  1LX5 A;  2QJA A;  4EC7 A;  4MQW A;  1CZ8 V;  5HHC A;  1QFW A;  1HCN B;  3HH2 A;  1B98 A;  1KLC A;  2P6A A;  2ASK A;  1WWW V;  1REW A;  4QHU C;  1MJV A;  2ARP A;  5JZ7 A;  4QAF C;  4UI0 A;  1AOC A;  2R53 A;  1SG1 A;  5AEJ A;  2C7W A;  1AGQ A;  2GH0 C;  1S4Y B;  1FZV A;  3BDY V;  1ZKZ A;  2VPF A;  1RV6 V;  3BUK A;  4UHY A;  1WAQ A;  4LXS J;  2FJH V;  4KV5 A;  1WQ8 A;  1FLT V;  5BQC A;  2X1X E;  2B0U A;  4KZN A;  3MJG A;  4AY9 B;  1BJ1 V;  1NYU B;  1SGF B;  2R52 A;  4HSA A;  3S1K V;  1HRP B;  3QTK A;  4UI2 B;  2KD3 A;  2VXS A;  4MQW B;  4YCI C;  1QFW B;  2FJG V;  4WPB A;  5HK5 E;  5F3B C;  2QCQ A;  3V6B A;  1WQ9 A;  3QB4 A; 
#chains in the Genus database with same CATH topology
 2BHK A;  2GYR A;  1ES7 A;  2GYZ A;  1BND A;  1KAT W;  4GLN E;  3P9W A;  4EDW V;  1TGK A;  5BQ8 D;  1TFG A;  2QR0 C;  3BMP A;  4ZBN A;  1B8M A;  4GLS E;  1BMP A;  3EVS B;  5BQE A;  1PDG A;  2QJ9 A;  5HK5 A;  1BTG A;  4UHZ A;  1XWD A;  4XPJ A;  3KFD A;  2QJB A;  2QCW A;  4ZFF C;  1B8K A;  3SEK B;  1NT3 A;  4LXR J;  2GOO A;  3S1B V;  4EAX A;  4QCI C;  2VWE A;  1KLA A;  1M4U A;  2PJY A;  1TZI V;  3RJR A;  5HI5 A;  3MJK A;  3FUB B;  3IJ2 A;  4KXZ A;  4N1D A;  1REU A;  1E9J A;  1WQ9 B;  4MID A;  5BQ8 A;  2TGI A;  1FL7 A;  1LXI A;  1BND B;  2V5E B;  2GNN A;  4UI1 A;  1HCN A;  1KTZ A;  2H64 A;  5BPU A;  3V2A A;  5E4G A;  2XV7 A;  4YCG C;  1B8M B;  5BQE B;  2IFG E;  1TZH V;  1DZ7 A;  1NYS B;  1XWD B;  3B4V A;  2XAC A;  3BK3 A;  1HCF A;  4MPL A;  4EFV A;  5FV1 V;  5FV2 V;  1MKK A;  2X1W A;  4EDX V;  2H62 A;  3E07 A;  3EO1 C;  4HR9 A;  2ARV A;  1JPY A;  5HI4 A;  5HHX A;  5HHD A;  1VPP V;  1QTY R;  5HHV A;  4X1J A;  5HI3 A;  1VPF A;  4AY9 A;  5BQB A;  4HQU A;  1TGJ A;  1M4U L;  1BET A;  1MKG A;  3JVF A;  5BQ8 B;  4BV4 L;  1FL7 B;  4FAO A;  1HD4 A;  1HRP A;  5F3H I;  4HQX A;  1LX5 A;  2QJA A;  4EC7 A;  4MQW A;  1CZ8 V;  5HHC A;  1QFW A;  1HCN B;  3HH2 A;  1B98 A;  1KLC A;  2P6A A;  2ASK A;  1WWW V;  1REW A;  4QHU C;  1MJV A;  2ARP A;  5JZ7 A;  4QAF C;  4UI0 A;  1AOC A;  2R53 A;  1SG1 A;  5AEJ A;  2C7W A;  1AGQ A;  2GH0 C;  1S4Y B;  1FZV A;  3BDY V;  1ZKZ A;  2VPF A;  1RV6 V;  3BUK A;  4UHY A;  1WAQ A;  4LXS J;  2FJH V;  4KV5 A;  1WQ8 A;  1FLT V;  5BQC A;  2X1X E;  2B0U A;  4KZN A;  3MJG A;  4AY9 B;  1BJ1 V;  1NYU B;  1SGF B;  2R52 A;  4HSA A;  3S1K V;  1HRP B;  3QTK A;  4UI2 B;  2KD3 A;  2VXS A;  4MQW B;  4YCI C;  1QFW B;  2FJG V;  4WPB A;  5HK5 E;  5F3B C;  2QCQ A;  3V6B A;  1WQ9 A;  3QB4 A; 
#chains in the Genus database with same CATH homology
 2BHK A;  2GYR A;  1ES7 A;  2GYZ A;  1BND A;  1KAT W;  4GLN E;  3P9W A;  4EDW V;  1TGK A;  5BQ8 D;  1TFG A;  2QR0 C;  3BMP A;  4ZBN A;  1B8M A;  4GLS E;  1BMP A;  3EVS B;  5BQE A;  1PDG A;  2QJ9 A;  5HK5 A;  1BTG A;  4UHZ A;  1XWD A;  4XPJ A;  3KFD A;  2QJB A;  2QCW A;  4ZFF C;  1B8K A;  3SEK B;  1NT3 A;  4LXR J;  2GOO A;  3S1B V;  4EAX A;  4QCI C;  2VWE A;  1KLA A;  1M4U A;  2PJY A;  1TZI V;  3RJR A;  5HI5 A;  3MJK A;  3FUB B;  3IJ2 A;  4KXZ A;  4N1D A;  1REU A;  1E9J A;  1WQ9 B;  4MID A;  5BQ8 A;  2TGI A;  1FL7 A;  1LXI A;  1BND B;  2V5E B;  2GNN A;  4UI1 A;  1HCN A;  1KTZ A;  2H64 A;  5BPU A;  3V2A A;  5E4G A;  2XV7 A;  4YCG C;  1B8M B;  5BQE B;  2IFG E;  1TZH V;  1DZ7 A;  1NYS B;  1XWD B;  3B4V A;  2XAC A;  3BK3 A;  1HCF A;  4MPL A;  4EFV A;  5FV1 V;  5FV2 V;  1MKK A;  2X1W A;  4EDX V;  2H62 A;  3E07 A;  3EO1 C;  4HR9 A;  2ARV A;  1JPY A;  5HI4 A;  5HHX A;  5HHD A;  1VPP V;  1QTY R;  5HHV A;  4X1J A;  5HI3 A;  1VPF A;  4AY9 A;  5BQB A;  4HQU A;  1TGJ A;  1M4U L;  1BET A;  1MKG A;  3JVF A;  5BQ8 B;  4BV4 L;  1FL7 B;  4FAO A;  1HD4 A;  1HRP A;  5F3H I;  4HQX A;  1LX5 A;  2QJA A;  4EC7 A;  4MQW A;  1CZ8 V;  5HHC A;  1QFW A;  1HCN B;  3HH2 A;  1B98 A;  1KLC A;  2P6A A;  2ASK A;  1WWW V;  1REW A;  4QHU C;  1MJV A;  2ARP A;  5JZ7 A;  4QAF C;  4UI0 A;  1AOC A;  2R53 A;  1SG1 A;  5AEJ A;  2C7W A;  1AGQ A;  2GH0 C;  1S4Y B;  1FZV A;  3BDY V;  1ZKZ A;  2VPF A;  1RV6 V;  3BUK A;  4UHY A;  1WAQ A;  4LXS J;  2FJH V;  4KV5 A;  1WQ8 A;  1FLT V;  5BQC A;  2X1X E;  2B0U A;  4KZN A;  3MJG A;  4AY9 B;  1BJ1 V;  1NYU B;  1SGF B;  2R52 A;  4HSA A;  3S1K V;  1HRP B;  3QTK A;  4UI2 B;  2KD3 A;  2VXS A;  4MQW B;  4YCI C;  1QFW B;  2FJG V;  4WPB A;  5HK5 E;  5F3B C;  2QCQ A;  3V6B A;  1WQ9 A;  3QB4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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