1HD4A

Solution structure of the a-subunit of human chorionic gonadotropin [modeled with diantennary glycan at asn78]
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
92
structure length
92
Chain Sequence
APDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effects of the N-Linked Glycans on the 3D Structure of the Free A-Subunit of Human Chorionic Gonadotropin
pubmed doi rcsb
molecule tags Glycoprotein
molecule keywords CHORIONIC GONADOTROPIN
total genus 3
structure length 92
sequence length 92
ec nomenclature
pdb deposition date 2000-11-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 1hd4A00
2QJ9A 3BUKA 2QJAA 1TGJA 1KLCA 2XV7A 2ARPA 4XPJA 5BQCA 1TFGA 3JVFA 4YCIC 1HRPB 4FAOA 1VPPV 1B8MB 1WAQA 4QCIC 4MQWB 1ZKZA 2H62A 1REUA 1WQ9B 4HQUA 1HD4A 4GLNE 1SGFB 1B8KA 1FL7B 1BTGA 5E4GA 2IFGE 5HI4A 5HI3A 1TZIV 4HQXA 3S1BV 2GNNA 1KATW 1FZVA 3QB4A 3QTKA 4UI0A 5HHVA 2C7WA 1BETA 2P6AA 3BMPA 1ES7A 2FJGV 4MIDA 2PJYA 5F3HI 5BQEB 1HRPA 1B8MA 2QJBA 4N1DA 4X1JA 2TGIA 4MQWA 4EC7A 1QTYR 1WQ9A 2QR0C 1DZ7A 1AGQA 5HHXA 2X1WA 4AY9B 1FL7A 3FUBB 1QFWB 1NYUB 3MJGA 4AY9A 1BNDB 1FLTV 5F3BC 4HSAA 3V2AA 1S4YB 1HCFA 1NYSB 4ZFFC 4KXZA 3HH2A 5BPUA 5BQ8D 1WWWV 2R53A 3MJKA 1JPYA 1TGKA 5FV1V 1BJ1V 4ZBNA 3EVSB 4KV5A 1NT3A 3E07A 3SEKB 1AOCA 1WQ8A 4LXSJ 1E9JA 1LXIA 3KFDA 5HK5E 2B0UA 3P9WA 2GYRA 1SG1A 5BQEA 5BQ8B 5HK5A 1RV6V 1MKGA 1LX5A 1TZHV 2ASKA 3BK3A 3EO1C 5BQBA 5HHDA 4EAXA 5HHCA 2R52A 2V5EB 4EDXV 1M4UA 1QFWA 4KZNA 5JZ7A 4UHYA 4WPBA 1VPFA 1MKKA 1BNDA 2GYZA 2KD3A 2X1XE 3RJRA 2ARVA 4EDWV 5AEJA 4LXRJ 2VXSA 4YCGC 2VWEA 5HI5A 3IJ2A 2BHKA 4QAFC 2QCQA 4GLSE 3V6BA 4BV4L 4UI1A 3S1KV 3BDYV 2GH0C 2VPFA 5FV2V 2GOOA 2H64A 1REWA 4EFVA 1HCNB 1BMPA 2FJHV 2QCWA 1HCNA 1KTZA 1XWDB 5BQ8A 1XWDA 4UI2B 4QHUC 1PDGA 4MPLA 4HR9A 1CZ8V 1B98A 4UHZA 2XACA 1KLAA 1MJVA 3B4VA 1M4UL
chains in the Genus database with same CATH superfamily
2QJ9A 3BUKA 2QJAA 1TGJA 1KLCA 2XV7A 2ARPA 4XPJA 5BQCA 1TFGA 3JVFA 4YCIC 1HRPB 4FAOA 1VPPV 1B8MB 1WAQA 4QCIC 4MQWB 1ZKZA 2H62A 1REUA 1WQ9B 4HQUA 1HD4A 4GLNE 1SGFB 1B8KA 1FL7B 1BTGA 5E4GA 2IFGE 5HI4A 5HI3A 1TZIV 4HQXA 3S1BV 2GNNA 1KATW 1FZVA 3QB4A 3QTKA 4UI0A 5HHVA 2C7WA 1BETA 2P6AA 3BMPA 1ES7A 2FJGV 4MIDA 2PJYA 5F3HI 5BQEB 1HRPA 1B8MA 2QJBA 4N1DA 4X1JA 2TGIA 4MQWA 4EC7A 1QTYR 1WQ9A 2QR0C 1DZ7A 1AGQA 5HHXA 2X1WA 4AY9B 1FL7A 3FUBB 1QFWB 1NYUB 3MJGA 4AY9A 1BNDB 1FLTV 5F3BC 4HSAA 3V2AA 1S4YB 1HCFA 1NYSB 4ZFFC 4KXZA 3HH2A 5BPUA 5BQ8D 1WWWV 2R53A 3MJKA 1JPYA 1TGKA 5FV1V 1BJ1V 4ZBNA 3EVSB 4KV5A 1NT3A 3E07A 3SEKB 1AOCA 1WQ8A 4LXSJ 1E9JA 1LXIA 3KFDA 5HK5E 2B0UA 3P9WA 2GYRA 1SG1A 5BQEA 5BQ8B 5HK5A 1RV6V 1MKGA 1LX5A 1TZHV 2ASKA 3BK3A 3EO1C 5BQBA 5HHDA 4EAXA 5HHCA 2R52A 2V5EB 4EDXV 1M4UA 1QFWA 4KZNA 5JZ7A 4UHYA 4WPBA 1VPFA 1MKKA 1BNDA 2GYZA 2KD3A 2X1XE 3RJRA 2ARVA 4EDWV 5AEJA 4LXRJ 2VXSA 4YCGC 2VWEA 5HI5A 3IJ2A 2BHKA 4QAFC 2QCQA 4GLSE 3V6BA 4BV4L 4UI1A 3S1KV 3BDYV 2GH0C 2VPFA 5FV2V 2GOOA 2H64A 1REWA 4EFVA 1HCNB 1BMPA 2FJHV 2QCWA 1HCNA 1KTZA 1XWDB 5BQ8A 1XWDA 4UI2B 4QHUC 1PDGA 4MPLA 4HR9A 1CZ8V 1B98A 4UHZA 2XACA 1KLAA 1MJVA 3B4VA 1M4UL
chains in the Genus database with same CATH topology
2QJ9A 3BUKA 2QJAA 1TGJA 1KLCA 2XV7A 2ARPA 4XPJA 5BQCA 1TFGA 3JVFA 4YCIC 1HRPB 4FAOA 1VPPV 1B8MB 1WAQA 4QCIC 4MQWB 1ZKZA 2H62A 1REUA 1WQ9B 4HQUA 1HD4A 4GLNE 1SGFB 1B8KA 1FL7B 1BTGA 5E4GA 2IFGE 5HI4A 5HI3A 1TZIV 4HQXA 3S1BV 2GNNA 1KATW 1FZVA 3QB4A 3QTKA 4UI0A 5HHVA 2C7WA 1BETA 2P6AA 3BMPA 1ES7A 2FJGV 4MIDA 2PJYA 5F3HI 5BQEB 1HRPA 1B8MA 2QJBA 4N1DA 4X1JA 2TGIA 4MQWA 4EC7A 1QTYR 1WQ9A 2QR0C 1DZ7A 1AGQA 5HHXA 2X1WA 4AY9B 1FL7A 3FUBB 1QFWB 1NYUB 3MJGA 4AY9A 1BNDB 1FLTV 5F3BC 4HSAA 3V2AA 1S4YB 1HCFA 1NYSB 4ZFFC 4KXZA 3HH2A 5BPUA 5BQ8D 1WWWV 2R53A 3MJKA 1JPYA 1TGKA 5FV1V 1BJ1V 4ZBNA 3EVSB 4KV5A 1NT3A 3E07A 3SEKB 1AOCA 1WQ8A 4LXSJ 1E9JA 1LXIA 3KFDA 5HK5E 2B0UA 3P9WA 2GYRA 1SG1A 5BQEA 5BQ8B 5HK5A 1RV6V 1MKGA 1LX5A 1TZHV 2ASKA 3BK3A 3EO1C 5BQBA 5HHDA 4EAXA 5HHCA 2R52A 2V5EB 4EDXV 1M4UA 1QFWA 4KZNA 5JZ7A 4UHYA 4WPBA 1VPFA 1MKKA 1BNDA 2GYZA 2KD3A 2X1XE 3RJRA 2ARVA 4EDWV 5AEJA 4LXRJ 2VXSA 4YCGC 2VWEA 5HI5A 3IJ2A 2BHKA 4QAFC 2QCQA 4GLSE 3V6BA 4BV4L 4UI1A 3S1KV 3BDYV 2GH0C 2VPFA 5FV2V 2GOOA 2H64A 1REWA 4EFVA 1HCNB 1BMPA 2FJHV 2QCWA 1HCNA 1KTZA 1XWDB 5BQ8A 1XWDA 4UI2B 4QHUC 1PDGA 4MPLA 4HR9A 1CZ8V 1B98A 4UHZA 2XACA 1KLAA 1MJVA 3B4VA 1M4UL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJ9 A;  3BUK A;  2QJA A;  1TGJ A;  1KLC A;  2XV7 A;  2ARP A;  4XPJ A;  5BQC A;  1TFG A;  3JVF A;  4YCI C;  1HRP B;  4FAO A;  1VPP V;  1B8M B;  1WAQ A;  4QCI C;  4MQW B;  1ZKZ A;  2H62 A;  1REU A;  1WQ9 B;  4HQU A;  1HD4 A;  4GLN E;  1SGF B;  1B8K A;  1FL7 B;  1BTG A;  5E4G A;  2IFG E;  5HI4 A;  5HI3 A;  1TZI V;  4HQX A;  3S1B V;  2GNN A;  1KAT W;  1FZV A;  3QB4 A;  3QTK A;  4UI0 A;  5HHV A;  2C7W A;  1BET A;  2P6A A;  3BMP A;  1ES7 A;  2FJG V;  4MID A;  2PJY A;  5F3H I;  5BQE B;  1HRP A;  1B8M A;  2QJB A;  4N1D A;  4X1J A;  2TGI A;  4MQW A;  4EC7 A;  1QTY R;  1WQ9 A;  2QR0 C;  1DZ7 A;  1AGQ A;  5HHX A;  2X1W A;  4AY9 B;  1FL7 A;  3FUB B;  1QFW B;  1NYU B;  3MJG A;  4AY9 A;  1BND B;  1FLT V;  5F3B C;  4HSA A;  3V2A A;  1S4Y B;  1HCF A;  1NYS B;  4ZFF C;  4KXZ A;  3HH2 A;  5BPU A;  5BQ8 D;  1WWW V;  2R53 A;  3MJK A;  1JPY A;  1TGK A;  5FV1 V;  1BJ1 V;  4ZBN A;  3EVS B;  4KV5 A;  1NT3 A;  3E07 A;  3SEK B;  1AOC A;  1WQ8 A;  4LXS J;  1E9J A;  1LXI A;  3KFD A;  5HK5 E;  2B0U A;  3P9W A;  2GYR A;  1SG1 A;  5BQE A;  5BQ8 B;  5HK5 A;  1RV6 V;  1MKG A;  1LX5 A;  1TZH V;  2ASK A;  3BK3 A;  3EO1 C;  5BQB A;  5HHD A;  4EAX A;  5HHC A;  2R52 A;  2V5E B;  4EDX V;  1M4U A;  1QFW A;  4KZN A;  5JZ7 A;  4UHY A;  4WPB A;  1VPF A;  1MKK A;  1BND A;  2GYZ A;  2KD3 A;  2X1X E;  3RJR A;  2ARV A;  4EDW V;  5AEJ A;  4LXR J;  2VXS A;  4YCG C;  2VWE A;  5HI5 A;  3IJ2 A;  2BHK A;  4QAF C;  2QCQ A;  4GLS E;  3V6B A;  4BV4 L;  4UI1 A;  3S1K V;  3BDY V;  2GH0 C;  2VPF A;  5FV2 V;  2GOO A;  2H64 A;  1REW A;  4EFV A;  1HCN B;  1BMP A;  2FJH V;  2QCW A;  1HCN A;  1KTZ A;  1XWD B;  5BQ8 A;  1XWD A;  4UI2 B;  4QHU C;  1PDG A;  4MPL A;  4HR9 A;  1CZ8 V;  1B98 A;  4UHZ A;  2XAC A;  1KLA A;  1MJV A;  3B4V A;  1M4U L; 
#chains in the Genus database with same CATH topology
 2QJ9 A;  3BUK A;  2QJA A;  1TGJ A;  1KLC A;  2XV7 A;  2ARP A;  4XPJ A;  5BQC A;  1TFG A;  3JVF A;  4YCI C;  1HRP B;  4FAO A;  1VPP V;  1B8M B;  1WAQ A;  4QCI C;  4MQW B;  1ZKZ A;  2H62 A;  1REU A;  1WQ9 B;  4HQU A;  1HD4 A;  4GLN E;  1SGF B;  1B8K A;  1FL7 B;  1BTG A;  5E4G A;  2IFG E;  5HI4 A;  5HI3 A;  1TZI V;  4HQX A;  3S1B V;  2GNN A;  1KAT W;  1FZV A;  3QB4 A;  3QTK A;  4UI0 A;  5HHV A;  2C7W A;  1BET A;  2P6A A;  3BMP A;  1ES7 A;  2FJG V;  4MID A;  2PJY A;  5F3H I;  5BQE B;  1HRP A;  1B8M A;  2QJB A;  4N1D A;  4X1J A;  2TGI A;  4MQW A;  4EC7 A;  1QTY R;  1WQ9 A;  2QR0 C;  1DZ7 A;  1AGQ A;  5HHX A;  2X1W A;  4AY9 B;  1FL7 A;  3FUB B;  1QFW B;  1NYU B;  3MJG A;  4AY9 A;  1BND B;  1FLT V;  5F3B C;  4HSA A;  3V2A A;  1S4Y B;  1HCF A;  1NYS B;  4ZFF C;  4KXZ A;  3HH2 A;  5BPU A;  5BQ8 D;  1WWW V;  2R53 A;  3MJK A;  1JPY A;  1TGK A;  5FV1 V;  1BJ1 V;  4ZBN A;  3EVS B;  4KV5 A;  1NT3 A;  3E07 A;  3SEK B;  1AOC A;  1WQ8 A;  4LXS J;  1E9J A;  1LXI A;  3KFD A;  5HK5 E;  2B0U A;  3P9W A;  2GYR A;  1SG1 A;  5BQE A;  5BQ8 B;  5HK5 A;  1RV6 V;  1MKG A;  1LX5 A;  1TZH V;  2ASK A;  3BK3 A;  3EO1 C;  5BQB A;  5HHD A;  4EAX A;  5HHC A;  2R52 A;  2V5E B;  4EDX V;  1M4U A;  1QFW A;  4KZN A;  5JZ7 A;  4UHY A;  4WPB A;  1VPF A;  1MKK A;  1BND A;  2GYZ A;  2KD3 A;  2X1X E;  3RJR A;  2ARV A;  4EDW V;  5AEJ A;  4LXR J;  2VXS A;  4YCG C;  2VWE A;  5HI5 A;  3IJ2 A;  2BHK A;  4QAF C;  2QCQ A;  4GLS E;  3V6B A;  4BV4 L;  4UI1 A;  3S1K V;  3BDY V;  2GH0 C;  2VPF A;  5FV2 V;  2GOO A;  2H64 A;  1REW A;  4EFV A;  1HCN B;  1BMP A;  2FJH V;  2QCW A;  1HCN A;  1KTZ A;  1XWD B;  5BQ8 A;  1XWD A;  4UI2 B;  4QHU C;  1PDG A;  4MPL A;  4HR9 A;  1CZ8 V;  1B98 A;  4UHZ A;  2XAC A;  1KLA A;  1MJV A;  3B4V A;  1M4U L; 
#chains in the Genus database with same CATH homology
 2QJ9 A;  3BUK A;  2QJA A;  1TGJ A;  1KLC A;  2XV7 A;  2ARP A;  4XPJ A;  5BQC A;  1TFG A;  3JVF A;  4YCI C;  1HRP B;  4FAO A;  1VPP V;  1B8M B;  1WAQ A;  4QCI C;  4MQW B;  1ZKZ A;  2H62 A;  1REU A;  1WQ9 B;  4HQU A;  1HD4 A;  4GLN E;  1SGF B;  1B8K A;  1FL7 B;  1BTG A;  5E4G A;  2IFG E;  5HI4 A;  5HI3 A;  1TZI V;  4HQX A;  3S1B V;  2GNN A;  1KAT W;  1FZV A;  3QB4 A;  3QTK A;  4UI0 A;  5HHV A;  2C7W A;  1BET A;  2P6A A;  3BMP A;  1ES7 A;  2FJG V;  4MID A;  2PJY A;  5F3H I;  5BQE B;  1HRP A;  1B8M A;  2QJB A;  4N1D A;  4X1J A;  2TGI A;  4MQW A;  4EC7 A;  1QTY R;  1WQ9 A;  2QR0 C;  1DZ7 A;  1AGQ A;  5HHX A;  2X1W A;  4AY9 B;  1FL7 A;  3FUB B;  1QFW B;  1NYU B;  3MJG A;  4AY9 A;  1BND B;  1FLT V;  5F3B C;  4HSA A;  3V2A A;  1S4Y B;  1HCF A;  1NYS B;  4ZFF C;  4KXZ A;  3HH2 A;  5BPU A;  5BQ8 D;  1WWW V;  2R53 A;  3MJK A;  1JPY A;  1TGK A;  5FV1 V;  1BJ1 V;  4ZBN A;  3EVS B;  4KV5 A;  1NT3 A;  3E07 A;  3SEK B;  1AOC A;  1WQ8 A;  4LXS J;  1E9J A;  1LXI A;  3KFD A;  5HK5 E;  2B0U A;  3P9W A;  2GYR A;  1SG1 A;  5BQE A;  5BQ8 B;  5HK5 A;  1RV6 V;  1MKG A;  1LX5 A;  1TZH V;  2ASK A;  3BK3 A;  3EO1 C;  5BQB A;  5HHD A;  4EAX A;  5HHC A;  2R52 A;  2V5E B;  4EDX V;  1M4U A;  1QFW A;  4KZN A;  5JZ7 A;  4UHY A;  4WPB A;  1VPF A;  1MKK A;  1BND A;  2GYZ A;  2KD3 A;  2X1X E;  3RJR A;  2ARV A;  4EDW V;  5AEJ A;  4LXR J;  2VXS A;  4YCG C;  2VWE A;  5HI5 A;  3IJ2 A;  2BHK A;  4QAF C;  2QCQ A;  4GLS E;  3V6B A;  4BV4 L;  4UI1 A;  3S1K V;  3BDY V;  2GH0 C;  2VPF A;  5FV2 V;  2GOO A;  2H64 A;  1REW A;  4EFV A;  1HCN B;  1BMP A;  2FJH V;  2QCW A;  1HCN A;  1KTZ A;  1XWD B;  5BQ8 A;  1XWD A;  4UI2 B;  4QHU C;  1PDG A;  4MPL A;  4HR9 A;  1CZ8 V;  1B98 A;  4UHZ A;  2XAC A;  1KLA A;  1MJV A;  3B4V A;  1M4U L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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