2GH0C

Growth factor/receptor complex
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
100
structure length
100
Chain Sequence
DPGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Artemin Complexed with Its Receptor GFRalpha3: Convergent Recognition of Glial Cell Line-Derived Neurotrophic Factors.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords artemin
total genus 15
structure length 100
sequence length 100
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-03-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 2gh0C00
1BETA 1HCNB 4QHUC 1M4UA 4XPJA 3HH2A 2B0UA 4HQUA 4LXSJ 3P9WA 4MPLA 1VPPV 3E07A 5BQEB 4GLSE 1NT3A 2QJBA 1B8MB 1LX5A 1TGJA 4HSAA 2X1WA 4QCIC 1AGQA 2ASKA 1MJVA 2H62A 4UHZA 2QCWA 1S4YB 1REWA 2QCQA 1HD4A 1QFWA 4AY9A 1CZ8V 1BNDA 3RJRA 1QFWB 5HK5A 4YCGC 1VPFA 1BNDB 5BQBA 1AOCA 4HQXA 1TGKA 1KLCA 4EDXV 4X1JA 5JZ7A 5BQEA 2V5EB 1SG1A 1B8MA 4UI2B 5HK5E 3S1KV 1ES7A 2ARPA 4KV5A 3MJKA 4UI1A 4EDWV 3IJ2A 3MJGA 4HR9A 5F3BC 1XWDB 3EVSB 4GLNE 1FL7A 2FJHV 1BTGA 1WWWV 5BQ8D 2H64A 1BJ1V 2GYRA 5HHCA 2GYZA 1NYSB 2VWEA 1REUA 2XV7A 1FL7B 2ARVA 4MQWB 4MIDA 5HI3A 4N1DA 3BMPA 1WQ9A 4UI0A 1MKKA 5BQ8B 4EFVA 1FLTV 1PDGA 1B98A 4ZBNA 2TGIA 2KD3A 5F3HI 3EO1C 1WQ9B 3S1BV 2PJYA 3B4VA 4ZFFC 2QJAA 1E9JA 1HRPA 4EAXA 1TFGA 2GOOA 2QR0C 1SGFB 4EC7A 1XWDA 1HRPB 4WPBA 2XACA 5FV2V 1DZ7A 3QB4A 5HI5A 1HCFA 1NYUB 5HHVA 4BV4L 4MQWA 1B8KA 1RV6V 3BK3A 5HHXA 2QJ9A 2P6AA 5BQ8A 5BQCA 1M4UL 5AEJA 1KTZA 2GH0C 2R53A 3BDYV 4LXRJ 2GNNA 3KFDA 1BMPA 5E4GA 5FV1V 1FZVA 1WAQA 2VPFA 1MKGA 2BHKA 1KLAA 4KXZA 2IFGE 2C7WA 3FUBB 1JPYA 2VXSA 4QAFC 5HHDA 1ZKZA 4YCIC 2FJGV 1TZHV 3V2AA 1LXIA 1TZIV 3SEKB 3QTKA 3BUKA 1WQ8A 2R52A 1HCNA 4AY9B 4UHYA 5BPUA 2X1XE 4KZNA 5HI4A 3V6BA 4FAOA 1KATW 3JVFA 1QTYR
chains in the Genus database with same CATH superfamily
1BETA 1HCNB 4QHUC 1M4UA 4XPJA 3HH2A 2B0UA 4HQUA 4LXSJ 3P9WA 4MPLA 1VPPV 3E07A 5BQEB 4GLSE 1NT3A 2QJBA 1B8MB 1LX5A 1TGJA 4HSAA 2X1WA 4QCIC 1AGQA 2ASKA 1MJVA 2H62A 4UHZA 2QCWA 1S4YB 1REWA 2QCQA 1HD4A 1QFWA 4AY9A 1CZ8V 1BNDA 3RJRA 1QFWB 5HK5A 4YCGC 1VPFA 1BNDB 5BQBA 1AOCA 4HQXA 1TGKA 1KLCA 4EDXV 4X1JA 5JZ7A 5BQEA 2V5EB 1SG1A 1B8MA 4UI2B 5HK5E 3S1KV 1ES7A 2ARPA 4KV5A 3MJKA 4UI1A 4EDWV 3IJ2A 3MJGA 4HR9A 5F3BC 1XWDB 3EVSB 4GLNE 1FL7A 2FJHV 1BTGA 1WWWV 5BQ8D 2H64A 1BJ1V 2GYRA 5HHCA 2GYZA 1NYSB 2VWEA 1REUA 2XV7A 1FL7B 2ARVA 4MQWB 4MIDA 5HI3A 4N1DA 3BMPA 1WQ9A 4UI0A 1MKKA 5BQ8B 4EFVA 1FLTV 1PDGA 1B98A 4ZBNA 2TGIA 2KD3A 5F3HI 3EO1C 1WQ9B 3S1BV 2PJYA 3B4VA 4ZFFC 2QJAA 1E9JA 1HRPA 4EAXA 1TFGA 2GOOA 2QR0C 1SGFB 4EC7A 1XWDA 1HRPB 4WPBA 2XACA 5FV2V 1DZ7A 3QB4A 5HI5A 1HCFA 1NYUB 5HHVA 4BV4L 4MQWA 1B8KA 1RV6V 3BK3A 5HHXA 2QJ9A 2P6AA 5BQ8A 5BQCA 1M4UL 5AEJA 1KTZA 2GH0C 2R53A 3BDYV 4LXRJ 2GNNA 3KFDA 1BMPA 5E4GA 5FV1V 1FZVA 1WAQA 2VPFA 1MKGA 2BHKA 1KLAA 4KXZA 2IFGE 2C7WA 3FUBB 1JPYA 2VXSA 4QAFC 5HHDA 1ZKZA 4YCIC 2FJGV 1TZHV 3V2AA 1LXIA 1TZIV 3SEKB 3QTKA 3BUKA 1WQ8A 2R52A 1HCNA 4AY9B 4UHYA 5BPUA 2X1XE 4KZNA 5HI4A 3V6BA 4FAOA 1KATW 3JVFA 1QTYR
chains in the Genus database with same CATH topology
1BETA 1HCNB 4QHUC 1M4UA 4XPJA 3HH2A 2B0UA 4HQUA 4LXSJ 3P9WA 4MPLA 1VPPV 3E07A 5BQEB 4GLSE 1NT3A 2QJBA 1B8MB 1LX5A 1TGJA 4HSAA 2X1WA 4QCIC 1AGQA 2ASKA 1MJVA 2H62A 4UHZA 2QCWA 1S4YB 1REWA 2QCQA 1HD4A 1QFWA 4AY9A 1CZ8V 1BNDA 3RJRA 1QFWB 5HK5A 4YCGC 1VPFA 1BNDB 5BQBA 1AOCA 4HQXA 1TGKA 1KLCA 4EDXV 4X1JA 5JZ7A 5BQEA 2V5EB 1SG1A 1B8MA 4UI2B 5HK5E 3S1KV 1ES7A 2ARPA 4KV5A 3MJKA 4UI1A 4EDWV 3IJ2A 3MJGA 4HR9A 5F3BC 1XWDB 3EVSB 4GLNE 1FL7A 2FJHV 1BTGA 1WWWV 5BQ8D 2H64A 1BJ1V 2GYRA 5HHCA 2GYZA 1NYSB 2VWEA 1REUA 2XV7A 1FL7B 2ARVA 4MQWB 4MIDA 5HI3A 4N1DA 3BMPA 1WQ9A 4UI0A 1MKKA 5BQ8B 4EFVA 1FLTV 1PDGA 1B98A 4ZBNA 2TGIA 2KD3A 5F3HI 3EO1C 1WQ9B 3S1BV 2PJYA 3B4VA 4ZFFC 2QJAA 1E9JA 1HRPA 4EAXA 1TFGA 2GOOA 2QR0C 1SGFB 4EC7A 1XWDA 1HRPB 4WPBA 2XACA 5FV2V 1DZ7A 3QB4A 5HI5A 1HCFA 1NYUB 5HHVA 4BV4L 4MQWA 1B8KA 1RV6V 3BK3A 5HHXA 2QJ9A 2P6AA 5BQ8A 5BQCA 1M4UL 5AEJA 1KTZA 2GH0C 2R53A 3BDYV 4LXRJ 2GNNA 3KFDA 1BMPA 5E4GA 5FV1V 1FZVA 1WAQA 2VPFA 1MKGA 2BHKA 1KLAA 4KXZA 2IFGE 2C7WA 3FUBB 1JPYA 2VXSA 4QAFC 5HHDA 1ZKZA 4YCIC 2FJGV 1TZHV 3V2AA 1LXIA 1TZIV 3SEKB 3QTKA 3BUKA 1WQ8A 2R52A 1HCNA 4AY9B 4UHYA 5BPUA 2X1XE 4KZNA 5HI4A 3V6BA 4FAOA 1KATW 3JVFA 1QTYR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BET A;  1HCN B;  4QHU C;  1M4U A;  4XPJ A;  3HH2 A;  2B0U A;  4HQU A;  4LXS J;  3P9W A;  4MPL A;  1VPP V;  3E07 A;  5BQE B;  4GLS E;  1NT3 A;  2QJB A;  1B8M B;  1LX5 A;  1TGJ A;  4HSA A;  2X1W A;  4QCI C;  1AGQ A;  2ASK A;  1MJV A;  2H62 A;  4UHZ A;  2QCW A;  1S4Y B;  1REW A;  2QCQ A;  1HD4 A;  1QFW A;  4AY9 A;  1CZ8 V;  1BND A;  3RJR A;  1QFW B;  5HK5 A;  4YCG C;  1VPF A;  1BND B;  5BQB A;  1AOC A;  4HQX A;  1TGK A;  1KLC A;  4EDX V;  4X1J A;  5JZ7 A;  5BQE A;  2V5E B;  1SG1 A;  1B8M A;  4UI2 B;  5HK5 E;  3S1K V;  1ES7 A;  2ARP A;  4KV5 A;  3MJK A;  4UI1 A;  4EDW V;  3IJ2 A;  3MJG A;  4HR9 A;  5F3B C;  1XWD B;  3EVS B;  4GLN E;  1FL7 A;  2FJH V;  1BTG A;  1WWW V;  5BQ8 D;  2H64 A;  1BJ1 V;  2GYR A;  5HHC A;  2GYZ A;  1NYS B;  2VWE A;  1REU A;  2XV7 A;  1FL7 B;  2ARV A;  4MQW B;  4MID A;  5HI3 A;  4N1D A;  3BMP A;  1WQ9 A;  4UI0 A;  1MKK A;  5BQ8 B;  4EFV A;  1FLT V;  1PDG A;  1B98 A;  4ZBN A;  2TGI A;  2KD3 A;  5F3H I;  3EO1 C;  1WQ9 B;  3S1B V;  2PJY A;  3B4V A;  4ZFF C;  2QJA A;  1E9J A;  1HRP A;  4EAX A;  1TFG A;  2GOO A;  2QR0 C;  1SGF B;  4EC7 A;  1XWD A;  1HRP B;  4WPB A;  2XAC A;  5FV2 V;  1DZ7 A;  3QB4 A;  5HI5 A;  1HCF A;  1NYU B;  5HHV A;  4BV4 L;  4MQW A;  1B8K A;  1RV6 V;  3BK3 A;  5HHX A;  2QJ9 A;  2P6A A;  5BQ8 A;  5BQC A;  1M4U L;  5AEJ A;  1KTZ A;  2GH0 C;  2R53 A;  3BDY V;  4LXR J;  2GNN A;  3KFD A;  1BMP A;  5E4G A;  5FV1 V;  1FZV A;  1WAQ A;  2VPF A;  1MKG A;  2BHK A;  1KLA A;  4KXZ A;  2IFG E;  2C7W A;  3FUB B;  1JPY A;  2VXS A;  4QAF C;  5HHD A;  1ZKZ A;  4YCI C;  2FJG V;  1TZH V;  3V2A A;  1LXI A;  1TZI V;  3SEK B;  3QTK A;  3BUK A;  1WQ8 A;  2R52 A;  1HCN A;  4AY9 B;  4UHY A;  5BPU A;  2X1X E;  4KZN A;  5HI4 A;  3V6B A;  4FAO A;  1KAT W;  3JVF A;  1QTY R; 
#chains in the Genus database with same CATH topology
 1BET A;  1HCN B;  4QHU C;  1M4U A;  4XPJ A;  3HH2 A;  2B0U A;  4HQU A;  4LXS J;  3P9W A;  4MPL A;  1VPP V;  3E07 A;  5BQE B;  4GLS E;  1NT3 A;  2QJB A;  1B8M B;  1LX5 A;  1TGJ A;  4HSA A;  2X1W A;  4QCI C;  1AGQ A;  2ASK A;  1MJV A;  2H62 A;  4UHZ A;  2QCW A;  1S4Y B;  1REW A;  2QCQ A;  1HD4 A;  1QFW A;  4AY9 A;  1CZ8 V;  1BND A;  3RJR A;  1QFW B;  5HK5 A;  4YCG C;  1VPF A;  1BND B;  5BQB A;  1AOC A;  4HQX A;  1TGK A;  1KLC A;  4EDX V;  4X1J A;  5JZ7 A;  5BQE A;  2V5E B;  1SG1 A;  1B8M A;  4UI2 B;  5HK5 E;  3S1K V;  1ES7 A;  2ARP A;  4KV5 A;  3MJK A;  4UI1 A;  4EDW V;  3IJ2 A;  3MJG A;  4HR9 A;  5F3B C;  1XWD B;  3EVS B;  4GLN E;  1FL7 A;  2FJH V;  1BTG A;  1WWW V;  5BQ8 D;  2H64 A;  1BJ1 V;  2GYR A;  5HHC A;  2GYZ A;  1NYS B;  2VWE A;  1REU A;  2XV7 A;  1FL7 B;  2ARV A;  4MQW B;  4MID A;  5HI3 A;  4N1D A;  3BMP A;  1WQ9 A;  4UI0 A;  1MKK A;  5BQ8 B;  4EFV A;  1FLT V;  1PDG A;  1B98 A;  4ZBN A;  2TGI A;  2KD3 A;  5F3H I;  3EO1 C;  1WQ9 B;  3S1B V;  2PJY A;  3B4V A;  4ZFF C;  2QJA A;  1E9J A;  1HRP A;  4EAX A;  1TFG A;  2GOO A;  2QR0 C;  1SGF B;  4EC7 A;  1XWD A;  1HRP B;  4WPB A;  2XAC A;  5FV2 V;  1DZ7 A;  3QB4 A;  5HI5 A;  1HCF A;  1NYU B;  5HHV A;  4BV4 L;  4MQW A;  1B8K A;  1RV6 V;  3BK3 A;  5HHX A;  2QJ9 A;  2P6A A;  5BQ8 A;  5BQC A;  1M4U L;  5AEJ A;  1KTZ A;  2GH0 C;  2R53 A;  3BDY V;  4LXR J;  2GNN A;  3KFD A;  1BMP A;  5E4G A;  5FV1 V;  1FZV A;  1WAQ A;  2VPF A;  1MKG A;  2BHK A;  1KLA A;  4KXZ A;  2IFG E;  2C7W A;  3FUB B;  1JPY A;  2VXS A;  4QAF C;  5HHD A;  1ZKZ A;  4YCI C;  2FJG V;  1TZH V;  3V2A A;  1LXI A;  1TZI V;  3SEK B;  3QTK A;  3BUK A;  1WQ8 A;  2R52 A;  1HCN A;  4AY9 B;  4UHY A;  5BPU A;  2X1X E;  4KZN A;  5HI4 A;  3V6B A;  4FAO A;  1KAT W;  3JVF A;  1QTY R; 
#chains in the Genus database with same CATH homology
 1BET A;  1HCN B;  4QHU C;  1M4U A;  4XPJ A;  3HH2 A;  2B0U A;  4HQU A;  4LXS J;  3P9W A;  4MPL A;  1VPP V;  3E07 A;  5BQE B;  4GLS E;  1NT3 A;  2QJB A;  1B8M B;  1LX5 A;  1TGJ A;  4HSA A;  2X1W A;  4QCI C;  1AGQ A;  2ASK A;  1MJV A;  2H62 A;  4UHZ A;  2QCW A;  1S4Y B;  1REW A;  2QCQ A;  1HD4 A;  1QFW A;  4AY9 A;  1CZ8 V;  1BND A;  3RJR A;  1QFW B;  5HK5 A;  4YCG C;  1VPF A;  1BND B;  5BQB A;  1AOC A;  4HQX A;  1TGK A;  1KLC A;  4EDX V;  4X1J A;  5JZ7 A;  5BQE A;  2V5E B;  1SG1 A;  1B8M A;  4UI2 B;  5HK5 E;  3S1K V;  1ES7 A;  2ARP A;  4KV5 A;  3MJK A;  4UI1 A;  4EDW V;  3IJ2 A;  3MJG A;  4HR9 A;  5F3B C;  1XWD B;  3EVS B;  4GLN E;  1FL7 A;  2FJH V;  1BTG A;  1WWW V;  5BQ8 D;  2H64 A;  1BJ1 V;  2GYR A;  5HHC A;  2GYZ A;  1NYS B;  2VWE A;  1REU A;  2XV7 A;  1FL7 B;  2ARV A;  4MQW B;  4MID A;  5HI3 A;  4N1D A;  3BMP A;  1WQ9 A;  4UI0 A;  1MKK A;  5BQ8 B;  4EFV A;  1FLT V;  1PDG A;  1B98 A;  4ZBN A;  2TGI A;  2KD3 A;  5F3H I;  3EO1 C;  1WQ9 B;  3S1B V;  2PJY A;  3B4V A;  4ZFF C;  2QJA A;  1E9J A;  1HRP A;  4EAX A;  1TFG A;  2GOO A;  2QR0 C;  1SGF B;  4EC7 A;  1XWD A;  1HRP B;  4WPB A;  2XAC A;  5FV2 V;  1DZ7 A;  3QB4 A;  5HI5 A;  1HCF A;  1NYU B;  5HHV A;  4BV4 L;  4MQW A;  1B8K A;  1RV6 V;  3BK3 A;  5HHX A;  2QJ9 A;  2P6A A;  5BQ8 A;  5BQC A;  1M4U L;  5AEJ A;  1KTZ A;  2GH0 C;  2R53 A;  3BDY V;  4LXR J;  2GNN A;  3KFD A;  1BMP A;  5E4G A;  5FV1 V;  1FZV A;  1WAQ A;  2VPF A;  1MKG A;  2BHK A;  1KLA A;  4KXZ A;  2IFG E;  2C7W A;  3FUB B;  1JPY A;  2VXS A;  4QAF C;  5HHD A;  1ZKZ A;  4YCI C;  2FJG V;  1TZH V;  3V2A A;  1LXI A;  1TZI V;  3SEK B;  3QTK A;  3BUK A;  1WQ8 A;  2R52 A;  1HCN A;  4AY9 B;  4UHY A;  5BPU A;  2X1X E;  4KZN A;  5HI4 A;  3V6B A;  4FAO A;  1KAT W;  3JVF A;  1QTY R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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