2GJWA

Rna recognition and cleavage by an splicing endonuclease
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
308
structure length
308
Chain Sequence
HHHHIGGDFAVVKAKKSLERRGFGVKRGDKIYLHPLEVVYLQIKGIESFGELEDVLSWAESRMEDFSTYYFVYEDLRDRGNKVKIQGEFLLTKKPYLPISERKTIRMEEIAEKARNFDELRLAVVDEESEITYFRVYEPDMMGEQKEELPEIAGVLSDEYVITKQTEIFSRYFYGSEKGDLVTLSLIESLYLLDLGKLNLLNADREELVKRAREVERNFDRRYEVYRNLKERGFVVKTGFKFGSEFRVYRKVESVDDLPHSEYLVDIADSREIRLIDLARAVRLAQNVRKRMVFAYGKNYLCFERVKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title RNA Recognition and Cleavage by an Splicing Endonuclease
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Archaeoglobus fulgidus
molecule keywords 5'-R(*GP*CP*GP*AP*CP*CP*GP*AP*CP*CP*AP*(DU)P*AP*GP*CP*UP*GP*
total genus 96
structure length 308
sequence length 308
chains with identical sequence B, C, D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2006-03-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
A PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 2gjwA02
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 2gjwA03
3.40.1350.150 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 2gjwA01
1HH1A 2GJWA 3AJVA 1GEFA 4QBLA 2WCZA 2OSTA 2VLDA 2FCOA 1IPIA 2OKFA 3DNXA 3IEYB 4FZ2A 1XMXA 1T0FA 1RZNA 4QBNA 1F1ZA 2WJ0A 3P1ZB 2INBA 3IEYA 1RLVA 1R11A 5FDKA 3IF0X 1OB8A 2WCWA 3P1YA 4QBOA 4TKKA 2WIZA 1Y88A 3P1ZA 2ZYZB 1ZP7A 1R0VA 1Y1OA 2CV8A 1OB9A 4TKDA 3FOVA 2WIWA 3AJVB 2ZYZA 1A79A 2EO0A 2GW6A
chains in the Genus database with same CATH superfamily
3BT7A 2O8FA 1NNEA 1GEFA 4DAVA 2FWRA 1XMXA 1T0FA 4QBNA 2O8BA 3THYB 3IF0X 2VS1A 4E6ZA 1Y1OA 2O8FB 2WTUA 2ZYZA 1A79A 2O8CB 1HH1A 2OSTA 1E3MA 2O8BB 2FCOA 2OKFA 2O8CA 2JJQA 1RZNA 2FKCA 3P1ZB 3THWB 2FKHB 2CZRA 1R11A 5FDKA 1OB8A 4QBOA 3P1ZA 2ZYZB 1ZP7A 3THWA 1WBBA 1FW6A 2BH2A 2O8DB 3FOVA 4G6UA 2WIWA 2EO0A 3AJVA 4QBLA 2O8DA 2WCZA 3ZLJA 3K0SA 3DNXA 1OH6A 4ZQUA 2W8MA 1NG9A 4EV1A 2WCWA 2FL3A 2FZ4A 2DBSA 2O8EA 1EWQA 1R0VA 4TKDA 3AJVB 4G6VA 4DAPA 4DA2A 2IXSA 2VLDA 2GW6A 1W7AA 2GJWA 1UWVA 1IPIA 1OH7A 3THXB 3IEYB 4LQEA 4FZ2A 1OH8A 1F1ZA 2WJ0A 1OH5A 2INBA 3IEYA 3THXA 1RLVA 2O8EB 1WBDA 3P1YA 4TKKA 2WIZA 2FLCA 1Y88A 3THYA 2Z0RA 1WB9A 2CV8A 1OB9A 1YNMA
chains in the Genus database with same CATH topology
1HH1A 2GJWA 3AJVA 3BT7A 1GEFA 4QBLA 2WCZA 2OSTA 1UWVA 4DAVA 2VLDA 2FCOA 1IPIA 2OKFA 3DNXA 4LQEA 3IEYB 4FZ2A 1XMXA 2JJQA 4ZQUA 2W8MA 1T0FA 1RZNA 4QBNA 1F1ZA 2WJ0A 2FKCA 3P1ZB 4EV1A 2INBA 2FKHB 3IEYA 2CZRA 1RLVA 2BH2A 1R11A 3IF0X 5FDKA 1OB8A 2WCWA 3P1YA 4QBOA 4TKKA 2WIZA 2FL3A 2VS1A 1Y88A 2FLCA 3P1ZA 2ZYZB 2DBSA 1ZP7A 2Z0RA 4E6ZA 1R0VA 1Y1OA 2CV8A 1OB9A 4TKDA 3FOVA 4G6UA 3AJVB 1YNMA 2ZYZA 4G6VA 2WIWA 1A79A 2EO0A 4DAPA 4DA2A 2IXSA 2GW6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HH1 A;  2GJW A;  3AJV A;  1GEF A;  4QBL A;  2WCZ A;  2OST A;  2VLD A;  2FCO A;  1IPI A;  2OKF A;  3DNX A;  3IEY B;  4FZ2 A;  1XMX A;  1T0F A;  1RZN A;  4QBN A;  1F1Z A;  2WJ0 A;  3P1Z B;  2INB A;  3IEY A;  1RLV A;  1R11 A;  5FDK A;  3IF0 X;  1OB8 A;  2WCW A;  3P1Y A;  4QBO A;  4TKK A;  2WIZ A;  1Y88 A;  3P1Z A;  2ZYZ B;  1ZP7 A;  1R0V A;  1Y1O A;  2CV8 A;  1OB9 A;  4TKD A;  3FOV A;  2WIW A;  3AJV B;  2ZYZ A;  1A79 A;  2EO0 A;  2GW6 A; 
#chains in the Genus database with same CATH topology
 3BT7 A;  2O8F A;  1NNE A;  1GEF A;  4DAV A;  2FWR A;  1XMX A;  1T0F A;  4QBN A;  2O8B A;  3THY B;  3IF0 X;  2VS1 A;  4E6Z A;  1Y1O A;  2O8F B;  2WTU A;  2ZYZ A;  1A79 A;  2O8C B;  1HH1 A;  2OST A;  1E3M A;  2O8B B;  2FCO A;  2OKF A;  2O8C A;  2JJQ A;  1RZN A;  2FKC A;  3P1Z B;  3THW B;  2FKH B;  2CZR A;  1R11 A;  5FDK A;  1OB8 A;  4QBO A;  3P1Z A;  2ZYZ B;  1ZP7 A;  3THW A;  1WBB A;  1FW6 A;  2BH2 A;  2O8D B;  3FOV A;  4G6U A;  2WIW A;  2EO0 A;  3AJV A;  4QBL A;  2O8D A;  2WCZ A;  3ZLJ A;  3K0S A;  3DNX A;  1OH6 A;  4ZQU A;  2W8M A;  1NG9 A;  4EV1 A;  2WCW A;  2FL3 A;  2FZ4 A;  2DBS A;  2O8E A;  1EWQ A;  1R0V A;  4TKD A;  3AJV B;  4G6V A;  4DAP A;  4DA2 A;  2IXS A;  2VLD A;  2GW6 A;  1W7A A;  2GJW A;  1UWV A;  1IPI A;  1OH7 A;  3THX B;  3IEY B;  4LQE A;  4FZ2 A;  1OH8 A;  1F1Z A;  2WJ0 A;  1OH5 A;  2INB A;  3IEY A;  3THX A;  1RLV A;  2O8E B;  1WBD A;  3P1Y A;  4TKK A;  2WIZ A;  2FLC A;  1Y88 A;  3THY A;  2Z0R A;  1WB9 A;  2CV8 A;  1OB9 A;  1YNM A; 
#chains in the Genus database with same CATH homology
 1HH1 A;  2GJW A;  3AJV A;  3BT7 A;  1GEF A;  4QBL A;  2WCZ A;  2OST A;  1UWV A;  4DAV A;  2VLD A;  2FCO A;  1IPI A;  2OKF A;  3DNX A;  4LQE A;  3IEY B;  4FZ2 A;  1XMX A;  2JJQ A;  4ZQU A;  2W8M A;  1T0F A;  1RZN A;  4QBN A;  1F1Z A;  2WJ0 A;  2FKC A;  3P1Z B;  4EV1 A;  2INB A;  2FKH B;  3IEY A;  2CZR A;  1RLV A;  2BH2 A;  1R11 A;  3IF0 X;  5FDK A;  1OB8 A;  2WCW A;  3P1Y A;  4QBO A;  4TKK A;  2WIZ A;  2FL3 A;  2VS1 A;  1Y88 A;  2FLC A;  3P1Z A;  2ZYZ B;  2DBS A;  1ZP7 A;  2Z0R A;  4E6Z A;  1R0V A;  1Y1O A;  2CV8 A;  1OB9 A;  4TKD A;  3FOV A;  4G6U A;  3AJV B;  1YNM A;  2ZYZ A;  4G6V A;  2WIW A;  1A79 A;  2EO0 A;  4DAP A;  4DA2 A;  2IXS A;  2GW6 A; 
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