3AJVB

Splicing endonuclease from aeropyrum pernix
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDAAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 52
structure length 180
sequence length 180
chains with identical sequence D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3ajvB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3ajvB02
4QBOA 1RLVA 1GEFA 2OKFA 3AJVA 2GW6A 1R11A 4QBLA 1HH1A 1IPIA 2GJWA 2ZYZB 2FCOA 1T0FA 2INBA 1Y1OA 2WCWA 3P1ZA 4FZ2A 2WCZA 3AJVB 3IEYA 1XMXA 1A79A 3P1YA 5FDKA 3FOVA 2WIWA 1ZP7A 2WIZA 4TKDA 1F1ZA 1R0VA 2CV8A 1Y88A 4TKKA 1OB8A 2EO0A 2WJ0A 2ZYZA 2OSTA 2VLDA 1OB9A 3DNXA 3P1ZB 1RZNA 4QBNA
chains in the Genus database with same CATH superfamily
2FZ4A 3IF0X 2IXSA 1NG9A 1IPIA 2FCOA 1OH6A 4ZQUA 3THYA 2WCZA 2W8MA 3IEYA 3K0SA 3P1YA 2Z0RA 4LQEA 1R0VA 1F1ZA 4TKKA 2WJ0A 2ZYZA 1NNEA 2VLDA 1OB9A 3DNXA 4DA2A 1EWQA 1RLVA 2O8CB 2OKFA 2GW6A 2O8DB 1FW6A 2BH2A 2GJWA 2DBSA 2ZYZB 1WBDA 2INBA 1Y1OA 2FL3A 3AJVB 1W7AA 3FOVA 2O8CA 2CV8A 2O8DA 1Y88A 4G6VA 2WTUA 1RZNA 1YNMA 1GEFA 3AJVA 1R11A 2CZRA 3THWA 1OH5A 1T0FA 1WB9A 4DAPA 4DAVA 2WCWA 3ZLJA 2FWRA 4FZ2A 1A79A 2VS1A 3THWB 2O8FB 2WIWA 1ZP7A 2WIZA 4TKDA 2JJQA 4EV1A 3P1ZB 1OH8A 3BT7A 2FLCA 4QBOA 4QBLA 2O8BB 1HH1A 3THXA 2O8EB 2FKCA 1UWVA 2O8FA 1WBBA 3P1ZA 4E6ZA 1XMXA 5FDKA 2FKHB 3THXB 1E3MA 4G6UA 2O8BA 2OSTA 1OB8A 2EO0A 2O8EA 3THYB 1OH7A 4QBNA 3IEYB
chains in the Genus database with same CATH topology
1YNMA 4QBOA 3IF0X 1RLVA 1GEFA 2OKFA 3AJVA 2GW6A 1R11A 2IXSA 2CZRA 4QBLA 1HH1A 2BH2A 2FKCA 1IPIA 1UWVA 2GJWA 2DBSA 2ZYZB 2FCOA 1T0FA 4ZQUA 2INBA 4DAPA 4DAVA 1Y1OA 2WCWA 2FL3A 3P1ZA 4FZ2A 2WCZA 2W8MA 4E6ZA 2OSTA 3AJVB 3IEYA 1XMXA 1A79A 2VS1A 3P1YA 2Z0RA 5FDKA 2FKHB 3FOVA 2WIWA 4LQEA 1ZP7A 2WIZA 4G6UA 4TKDA 1F1ZA 1R0VA 2CV8A 1Y88A 4TKKA 1OB8A 2EO0A 2WJ0A 2JJQA 2ZYZA 2VLDA 4G6VA 1OB9A 4EV1A 3DNXA 4DA2A 3P1ZB 1RZNA 3BT7A 4QBNA 3IEYB 2FLCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QBO A;  1RLV A;  1GEF A;  2OKF A;  3AJV A;  2GW6 A;  1R11 A;  4QBL A;  1HH1 A;  1IPI A;  2GJW A;  2ZYZ B;  2FCO A;  1T0F A;  2INB A;  1Y1O A;  2WCW A;  3P1Z A;  4FZ2 A;  2WCZ A;  3AJV B;  3IEY A;  1XMX A;  1A79 A;  3P1Y A;  5FDK A;  3FOV A;  2WIW A;  1ZP7 A;  2WIZ A;  4TKD A;  1F1Z A;  1R0V A;  2CV8 A;  1Y88 A;  4TKK A;  1OB8 A;  2EO0 A;  2WJ0 A;  2ZYZ A;  2OST A;  2VLD A;  1OB9 A;  3DNX A;  3P1Z B;  1RZN A;  4QBN A; 
#chains in the Genus database with same CATH topology
 2FZ4 A;  3IF0 X;  2IXS A;  1NG9 A;  1IPI A;  2FCO A;  1OH6 A;  4ZQU A;  3THY A;  2WCZ A;  2W8M A;  3IEY A;  3K0S A;  3P1Y A;  2Z0R A;  4LQE A;  1R0V A;  1F1Z A;  4TKK A;  2WJ0 A;  2ZYZ A;  1NNE A;  2VLD A;  1OB9 A;  3DNX A;  4DA2 A;  1EWQ A;  1RLV A;  2O8C B;  2OKF A;  2GW6 A;  2O8D B;  1FW6 A;  2BH2 A;  2GJW A;  2DBS A;  2ZYZ B;  1WBD A;  2INB A;  1Y1O A;  2FL3 A;  3AJV B;  1W7A A;  3FOV A;  2O8C A;  2CV8 A;  2O8D A;  1Y88 A;  4G6V A;  2WTU A;  1RZN A;  1YNM A;  1GEF A;  3AJV A;  1R11 A;  2CZR A;  3THW A;  1OH5 A;  1T0F A;  1WB9 A;  4DAP A;  4DAV A;  2WCW A;  3ZLJ A;  2FWR A;  4FZ2 A;  1A79 A;  2VS1 A;  3THW B;  2O8F B;  2WIW A;  1ZP7 A;  2WIZ A;  4TKD A;  2JJQ A;  4EV1 A;  3P1Z B;  1OH8 A;  3BT7 A;  2FLC A;  4QBO A;  4QBL A;  2O8B B;  1HH1 A;  3THX A;  2O8E B;  2FKC A;  1UWV A;  2O8F A;  1WBB A;  3P1Z A;  4E6Z A;  1XMX A;  5FDK A;  2FKH B;  3THX B;  1E3M A;  4G6U A;  2O8B A;  2OST A;  1OB8 A;  2EO0 A;  2O8E A;  3THY B;  1OH7 A;  4QBN A;  3IEY B; 
#chains in the Genus database with same CATH homology
 1YNM A;  4QBO A;  3IF0 X;  1RLV A;  1GEF A;  2OKF A;  3AJV A;  2GW6 A;  1R11 A;  2IXS A;  2CZR A;  4QBL A;  1HH1 A;  2BH2 A;  2FKC A;  1IPI A;  1UWV A;  2GJW A;  2DBS A;  2ZYZ B;  2FCO A;  1T0F A;  4ZQU A;  2INB A;  4DAP A;  4DAV A;  1Y1O A;  2WCW A;  2FL3 A;  3P1Z A;  4FZ2 A;  2WCZ A;  2W8M A;  4E6Z A;  2OST A;  3AJV B;  3IEY A;  1XMX A;  1A79 A;  2VS1 A;  3P1Y A;  2Z0R A;  5FDK A;  2FKH B;  3FOV A;  2WIW A;  4LQE A;  1ZP7 A;  2WIZ A;  4G6U A;  4TKD A;  1F1Z A;  1R0V A;  2CV8 A;  1Y88 A;  4TKK A;  1OB8 A;  2EO0 A;  2WJ0 A;  2JJQ A;  2ZYZ A;  2VLD A;  4G6V A;  1OB9 A;  4EV1 A;  3DNX A;  4DA2 A;  3P1Z B;  1RZN A;  3BT7 A;  4QBN A;  3IEY B;  2FLC A; 
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