3AJVB

Splicing endonuclease from aeropyrum pernix
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDAAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 52
structure length 180
sequence length 180
chains with identical sequence D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3ajvB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3ajvB02
2WIZA 2WIWA 1RZNA 3P1ZA 1OB9A 1XMXA 3AJVB 2EO0A 2WCZA 3P1YA 1A79A 2ZYZB 3FOVA 2INBA 4TKKA 1T0FA 1ZP7A 3P1ZB 1GEFA 3IEYA 1HH1A 1OB8A 2FCOA 1IPIA 4QBOA 1R11A 3DNXA 2OSTA 4TKDA 1Y88A 2WCWA 2GJWA 4QBLA 4FZ2A 2WJ0A 1F1ZA 3AJVA 4QBNA 1RLVA 1R0VA 1Y1OA 5FDKA 2ZYZA 2VLDA 2GW6A 2OKFA 2CV8A
chains in the Genus database with same CATH superfamily
3THYA 2WIWA 1XMXA 2O8BB 2O8DA 2ZYZB 4TKKA 1YNMA 1ZP7A 3THYB 2CZRA 2FKCA 1GEFA 2O8DB 1IPIA 4QBOA 1OH8A 2OSTA 4TKDA 2WTUA 1RLVA 1EWQA 4G6VA 1Y1OA 5FDKA 1WBDA 2BH2A 2GW6A 2DBSA 2Z0RA 1RZNA 4EV1A 2VS1A 3P1YA 2INBA 3ZLJA 1HH1A 1OB8A 2IXSA 2FCOA 3IF0X 2FWRA 4QBLA 2WJ0A 3THWA 4DA2A 2FL3A 2O8EB 2FKHB 1FW6A 2O8CB 2OKFA 2CV8A 4ZQUA 2WIZA 3P1ZA 1OB9A 4G6UA 3THWB 2EO0A 3FOVA 3BT7A 1T0FA 1UWVA 4E6ZA 3P1ZB 1OH5A 2W8MA 2O8EA 1W7AA 2O8CA 1Y88A 2WCWA 2GJWA 4FZ2A 3IEYB 3AJVA 2FZ4A 1WB9A 1E3MA 1OH6A 3THXA 2JJQA 4LQEA 3AJVB 2WCZA 1A79A 3THXB 1OH7A 1NNEA 3K0SA 3IEYA 4DAPA 2O8FA 1R11A 3DNXA 1WBBA 1NG9A 1F1ZA 4QBNA 1R0VA 2O8BA 4DAVA 2FLCA 2ZYZA 2O8FB 2VLDA
chains in the Genus database with same CATH topology
2WIZA 2WIWA 1RZNA 3P1ZA 1OB9A 1XMXA 2VS1A 4G6UA 3AJVB 4LQEA 4EV1A 2EO0A 2WCZA 3P1YA 1A79A 2ZYZB 3FOVA 2INBA 4TKKA 1YNMA 3BT7A 1T0FA 1ZP7A 1UWVA 4E6ZA 3P1ZB 2CZRA 2FKCA 1GEFA 3IEYA 1HH1A 1OB8A 2IXSA 4ZQUA 2FCOA 4DAPA 1IPIA 2W8MA 1R11A 3IF0X 4QBOA 3DNXA 2OSTA 4TKDA 1Y88A 2WCWA 2GJWA 4QBLA 4FZ2A 2WJ0A 3IEYB 1F1ZA 3AJVA 4QBNA 1RLVA 1R0VA 4G6VA 1Y1OA 4DA2A 5FDKA 4DAVA 2FL3A 2FLCA 2ZYZA 2FKHB 2VLDA 2JJQA 2BH2A 2GW6A 2OKFA 2CV8A 2DBSA 2Z0RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WIZ A;  2WIW A;  1RZN A;  3P1Z A;  1OB9 A;  1XMX A;  3AJV B;  2EO0 A;  2WCZ A;  3P1Y A;  1A79 A;  2ZYZ B;  3FOV A;  2INB A;  4TKK A;  1T0F A;  1ZP7 A;  3P1Z B;  1GEF A;  3IEY A;  1HH1 A;  1OB8 A;  2FCO A;  1IPI A;  4QBO A;  1R11 A;  3DNX A;  2OST A;  4TKD A;  1Y88 A;  2WCW A;  2GJW A;  4QBL A;  4FZ2 A;  2WJ0 A;  1F1Z A;  3AJV A;  4QBN A;  1RLV A;  1R0V A;  1Y1O A;  5FDK A;  2ZYZ A;  2VLD A;  2GW6 A;  2OKF A;  2CV8 A; 
#chains in the Genus database with same CATH topology
 3THY A;  2WIW A;  1XMX A;  2O8B B;  2O8D A;  2ZYZ B;  4TKK A;  1YNM A;  1ZP7 A;  3THY B;  2CZR A;  2FKC A;  1GEF A;  2O8D B;  1IPI A;  4QBO A;  1OH8 A;  2OST A;  4TKD A;  2WTU A;  1RLV A;  1EWQ A;  4G6V A;  1Y1O A;  5FDK A;  1WBD A;  2BH2 A;  2GW6 A;  2DBS A;  2Z0R A;  1RZN A;  4EV1 A;  2VS1 A;  3P1Y A;  2INB A;  3ZLJ A;  1HH1 A;  1OB8 A;  2IXS A;  2FCO A;  3IF0 X;  2FWR A;  4QBL A;  2WJ0 A;  3THW A;  4DA2 A;  2FL3 A;  2O8E B;  2FKH B;  1FW6 A;  2O8C B;  2OKF A;  2CV8 A;  4ZQU A;  2WIZ A;  3P1Z A;  1OB9 A;  4G6U A;  3THW B;  2EO0 A;  3FOV A;  3BT7 A;  1T0F A;  1UWV A;  4E6Z A;  3P1Z B;  1OH5 A;  2W8M A;  2O8E A;  1W7A A;  2O8C A;  1Y88 A;  2WCW A;  2GJW A;  4FZ2 A;  3IEY B;  3AJV A;  2FZ4 A;  1WB9 A;  1E3M A;  1OH6 A;  3THX A;  2JJQ A;  4LQE A;  3AJV B;  2WCZ A;  1A79 A;  3THX B;  1OH7 A;  1NNE A;  3K0S A;  3IEY A;  4DAP A;  2O8F A;  1R11 A;  3DNX A;  1WBB A;  1NG9 A;  1F1Z A;  4QBN A;  1R0V A;  2O8B A;  4DAV A;  2FLC A;  2ZYZ A;  2O8F B;  2VLD A; 
#chains in the Genus database with same CATH homology
 2WIZ A;  2WIW A;  1RZN A;  3P1Z A;  1OB9 A;  1XMX A;  2VS1 A;  4G6U A;  3AJV B;  4LQE A;  4EV1 A;  2EO0 A;  2WCZ A;  3P1Y A;  1A79 A;  2ZYZ B;  3FOV A;  2INB A;  4TKK A;  1YNM A;  3BT7 A;  1T0F A;  1ZP7 A;  1UWV A;  4E6Z A;  3P1Z B;  2CZR A;  2FKC A;  1GEF A;  3IEY A;  1HH1 A;  1OB8 A;  2IXS A;  4ZQU A;  2FCO A;  4DAP A;  1IPI A;  2W8M A;  1R11 A;  3IF0 X;  4QBO A;  3DNX A;  2OST A;  4TKD A;  1Y88 A;  2WCW A;  2GJW A;  4QBL A;  4FZ2 A;  2WJ0 A;  3IEY B;  1F1Z A;  3AJV A;  4QBN A;  1RLV A;  1R0V A;  4G6V A;  1Y1O A;  4DA2 A;  5FDK A;  4DAV A;  2FL3 A;  2FLC A;  2ZYZ A;  2FKH B;  2VLD A;  2JJQ A;  2BH2 A;  2GW6 A;  2OKF A;  2CV8 A;  2DBS A;  2Z0R A; 
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