3AJVB

Splicing endonuclease from aeropyrum pernix
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDAAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 52
structure length 180
sequence length 180
chains with identical sequence D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3ajvB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3ajvB02
2WCZA 2OKFA 2FCOA 2VLDA 2OSTA 2ZYZB 2WJ0A 1HH1A 1XMXA 1IPIA 4QBLA 5FDKA 4TKKA 3IEYA 4QBOA 1T0FA 3P1ZB 1Y88A 3P1YA 3DNXA 2GJWA 2GW6A 2WIZA 3AJVB 1Y1OA 2ZYZA 1RLVA 1F1ZA 4QBNA 2CV8A 1GEFA 1OB8A 1A79A 2WCWA 1R11A 3P1ZA 1RZNA 1ZP7A 2INBA 2WIWA 1R0VA 4TKDA 1OB9A 3AJVA 4FZ2A 2EO0A 3FOVA
chains in the Genus database with same CATH superfamily
2O8CB 2WCZA 2OKFA 2FCOA 4QBLA 5FDKA 3K0SA 3THWB 4E6ZA 3P1ZB 2O8CA 2VS1A 2GJWA 4G6UA 1RLVA 1OH7A 3THWA 2Z0RA 1FW6A 1WBDA 3P1ZA 2WIWA 2O8BB 1OB9A 1WB9A 2EO0A 1NNEA 1W7AA 4ZQUA 3THYB 2ZYZB 2O8FB 1HH1A 2FZ4A 1IPIA 2O8BA 4DAPA 4DA2A 4QBOA 3BT7A 1Y88A 3DNXA 4LQEA 1WBBA 2GW6A 2CZRA 2WIZA 3AJVB 1OH8A 1Y1OA 2ZYZA 1GEFA 1OB8A 2W8MA 2WCWA 1R11A 2FLCA 1R0VA 1NG9A 2O8EB 2FL3A 4TKDA 3IF0X 4G6VA 1EWQA 2VLDA 1E3MA 2OSTA 3THXB 1XMXA 2O8EA 4TKKA 3P1YA 1YNMA 1OH5A 3THXA 3THYA 1F1ZA 2CV8A 2O8FA 1ZP7A 2INBA 3AJVA 4FZ2A 3IEYB 2FKHB 2FKCA 2WTUA 2JJQA 2BH2A 1OH6A 2WJ0A 4DAVA 4EV1A 2O8DB 3IEYA 1T0FA 2IXSA 4QBNA 2FWRA 1A79A 2O8DA 1UWVA 1RZNA 2DBSA 3ZLJA 3FOVA
chains in the Genus database with same CATH topology
2WCZA 4G6VA 2OKFA 2FCOA 2VLDA 2JJQA 4ZQUA 2OSTA 2BH2A 2ZYZB 2WJ0A 1HH1A 1XMXA 4DAVA 1IPIA 4DAPA 4EV1A 4QBLA 4DA2A 5FDKA 4TKKA 3IEYA 4QBOA 1T0FA 4E6ZA 3P1ZB 3BT7A 1Y88A 3P1YA 2VS1A 2IXSA 2GJWA 3DNXA 1YNMA 2GW6A 3IEYB 2CZRA 4LQEA 2WIZA 3AJVB 4G6UA 1Y1OA 2ZYZA 1RLVA 1F1ZA 4QBNA 2CV8A 1GEFA 1OB8A 1A79A 2W8MA 1UWVA 2WCWA 2Z0RA 1R11A 3P1ZA 2FLCA 1RZNA 1ZP7A 2INBA 2WIWA 1R0VA 2DBSA 2FL3A 4TKDA 1OB9A 2FKCA 3AJVA 4FZ2A 2EO0A 3FOVA 2FKHB 3IF0X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WCZ A;  2OKF A;  2FCO A;  2VLD A;  2OST A;  2ZYZ B;  2WJ0 A;  1HH1 A;  1XMX A;  1IPI A;  4QBL A;  5FDK A;  4TKK A;  3IEY A;  4QBO A;  1T0F A;  3P1Z B;  1Y88 A;  3P1Y A;  3DNX A;  2GJW A;  2GW6 A;  2WIZ A;  3AJV B;  1Y1O A;  2ZYZ A;  1RLV A;  1F1Z A;  4QBN A;  2CV8 A;  1GEF A;  1OB8 A;  1A79 A;  2WCW A;  1R11 A;  3P1Z A;  1RZN A;  1ZP7 A;  2INB A;  2WIW A;  1R0V A;  4TKD A;  1OB9 A;  3AJV A;  4FZ2 A;  2EO0 A;  3FOV A; 
#chains in the Genus database with same CATH topology
 2O8C B;  2WCZ A;  2OKF A;  2FCO A;  4QBL A;  5FDK A;  3K0S A;  3THW B;  4E6Z A;  3P1Z B;  2O8C A;  2VS1 A;  2GJW A;  4G6U A;  1RLV A;  1OH7 A;  3THW A;  2Z0R A;  1FW6 A;  1WBD A;  3P1Z A;  2WIW A;  2O8B B;  1OB9 A;  1WB9 A;  2EO0 A;  1NNE A;  1W7A A;  4ZQU A;  3THY B;  2ZYZ B;  2O8F B;  1HH1 A;  2FZ4 A;  1IPI A;  2O8B A;  4DAP A;  4DA2 A;  4QBO A;  3BT7 A;  1Y88 A;  3DNX A;  4LQE A;  1WBB A;  2GW6 A;  2CZR A;  2WIZ A;  3AJV B;  1OH8 A;  1Y1O A;  2ZYZ A;  1GEF A;  1OB8 A;  2W8M A;  2WCW A;  1R11 A;  2FLC A;  1R0V A;  1NG9 A;  2O8E B;  2FL3 A;  4TKD A;  3IF0 X;  4G6V A;  1EWQ A;  2VLD A;  1E3M A;  2OST A;  3THX B;  1XMX A;  2O8E A;  4TKK A;  3P1Y A;  1YNM A;  1OH5 A;  3THX A;  3THY A;  1F1Z A;  2CV8 A;  2O8F A;  1ZP7 A;  2INB A;  3AJV A;  4FZ2 A;  3IEY B;  2FKH B;  2FKC A;  2WTU A;  2JJQ A;  2BH2 A;  1OH6 A;  2WJ0 A;  4DAV A;  4EV1 A;  2O8D B;  3IEY A;  1T0F A;  2IXS A;  4QBN A;  2FWR A;  1A79 A;  2O8D A;  1UWV A;  1RZN A;  2DBS A;  3ZLJ A;  3FOV A; 
#chains in the Genus database with same CATH homology
 2WCZ A;  4G6V A;  2OKF A;  2FCO A;  2VLD A;  2JJQ A;  4ZQU A;  2OST A;  2BH2 A;  2ZYZ B;  2WJ0 A;  1HH1 A;  1XMX A;  4DAV A;  1IPI A;  4DAP A;  4EV1 A;  4QBL A;  4DA2 A;  5FDK A;  4TKK A;  3IEY A;  4QBO A;  1T0F A;  4E6Z A;  3P1Z B;  3BT7 A;  1Y88 A;  3P1Y A;  2VS1 A;  2IXS A;  2GJW A;  3DNX A;  1YNM A;  2GW6 A;  3IEY B;  2CZR A;  4LQE A;  2WIZ A;  3AJV B;  4G6U A;  1Y1O A;  2ZYZ A;  1RLV A;  1F1Z A;  4QBN A;  2CV8 A;  1GEF A;  1OB8 A;  1A79 A;  2W8M A;  1UWV A;  2WCW A;  2Z0R A;  1R11 A;  3P1Z A;  2FLC A;  1RZN A;  1ZP7 A;  2INB A;  2WIW A;  1R0V A;  2DBS A;  2FL3 A;  4TKD A;  1OB9 A;  2FKC A;  3AJV A;  4FZ2 A;  2EO0 A;  3FOV A;  2FKH B;  3IF0 X; 
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