3P1YA

Crystal structure of the chimeric archaeoglobus fulgidus rna splicing endonuclease with the broadest substrate specificity
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
314
structure length
314
Chain Sequence
IGGDFAVVKAKKSLERRGFGVKRGDKIYLHPLEVVYLQIKGIESFGELEDVLSWAESRMEDFSTYYFVYEDLRDRGNKVKIQGEFLLTKKPYLPISERKTIRMEEIAEKARNFDELRLAVVDEESEITYFRVYEPDMMGEQKEELPEIAGILSDEYVITKQTEIFSRYFYGSPLDVEKPRGADFEGPVTLSLIESLYLLDLGKLNLLNADREELVKRAREVERNFDRRYEVYRNLKERGFVVKTGFKFGSEFRVYRKVESVDDLPHSEYLVDIADSREIRLIDLARAVRLAQNVRKRMVFAYGKNYLCFERVKV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords tRNA-splicing endonuclease
total genus 99
structure length 314
sequence length 314
chains with identical sequence B, C, D
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
A PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
A PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3p1yA02
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1yA03
3.40.1350.150 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1yA01
3AJVA 2OSTA 1Y88A 2GJWA 3FOVA 2WJ0A 4QBNA 3AJVB 2ZYZA 2CV8A 1OB8A 1HH1A 1RZNA 4TKKA 2FCOA 3P1ZA 2ZYZB 1XMXA 3P1YA 3P1ZB 3IF0X 4QBLA 2WIWA 3IEYA 1R0VA 2INBA 1F1ZA 1R11A 4QBOA 1GEFA 2WCZA 3IEYB 1A79A 3DNXA 1ZP7A 1Y1OA 2OKFA 1IPIA 1T0FA 2WIZA 4FZ2A 2VLDA 5FDKA 1OB9A 2EO0A 2WCWA 2GW6A 4TKDA 1RLVA
chains in the Genus database with same CATH superfamily
2OSTA 2JJQA 1NNEA 4ZQUA 3THXA 4TKKA 3P1ZA 3P1YA 3THXB 1WBDA 2O8BA 1R0VA 2O8BB 1F1ZA 2INBA 2WCZA 2FLCA 3DNXA 2OKFA 1OH5A 4E6ZA 2O8DB 2VLDA 5FDKA 1FW6A 2O8CA 2WCWA 1OH8A 1W7AA 2GJWA 2O8CB 3FOVA 4QBNA 2CV8A 1HH1A 4DAVA 2FCOA 4DA2A 4EV1A 4G6VA 3ZLJA 1OH6A 2W8MA 4QBOA 4G6UA 2O8EA 2O8DA 1IPIA 1T0FA 2O8EB 2CZRA 2EO0A 2Z0RA 3AJVA 2O8FB 1Y88A 1YNMA 3BT7A 2WJ0A 3AJVB 3THWB 1OB8A 2FZ4A 1RZNA 1OH7A 2WTUA 3IF0X 1EWQA 4QBLA 2WIWA 2DBSA 2FL3A 1NG9A 1GEFA 3IEYB 1UWVA 2VS1A 2IXSA 2WIZA 4LQEA 4DAPA 1OB9A 2O8FA 2FWRA 3THYB 3THWA 2ZYZA 2FKHB 1XMXA 2ZYZB 3P1ZB 2BH2A 3IEYA 1R11A 1WBBA 1A79A 1ZP7A 1WB9A 1Y1OA 1E3MA 3K0SA 4FZ2A 3THYA 2GW6A 4TKDA 1RLVA 2FKCA
chains in the Genus database with same CATH topology
3AJVA 2OSTA 1Y88A 2GJWA 1YNMA 3FOVA 2JJQA 3BT7A 2WJ0A 4QBNA 3AJVB 2ZYZA 2CV8A 1OB8A 4ZQUA 1HH1A 2Z0RA 1RZNA 4TKKA 4DAVA 2FCOA 3P1ZA 2ZYZB 1XMXA 4DA2A 2FKHB 4EV1A 4G6VA 3P1YA 3P1ZB 2W8MA 3IF0X 4QBLA 2WIWA 2DBSA 2FL3A 3IEYA 1R0VA 2BH2A 2INBA 1F1ZA 1R11A 4QBOA 1GEFA 2WCZA 3IEYB 1UWVA 4G6UA 2FLCA 1A79A 3DNXA 2VS1A 1ZP7A 1Y1OA 2IXSA 2OKFA 1IPIA 1T0FA 4E6ZA 2CZRA 2WIZA 4LQEA 4FZ2A 2VLDA 4DAPA 5FDKA 1OB9A 2EO0A 2WCWA 2GW6A 4TKDA 1RLVA 2FKCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AJV A;  2OST A;  1Y88 A;  2GJW A;  3FOV A;  2WJ0 A;  4QBN A;  3AJV B;  2ZYZ A;  2CV8 A;  1OB8 A;  1HH1 A;  1RZN A;  4TKK A;  2FCO A;  3P1Z A;  2ZYZ B;  1XMX A;  3P1Y A;  3P1Z B;  3IF0 X;  4QBL A;  2WIW A;  3IEY A;  1R0V A;  2INB A;  1F1Z A;  1R11 A;  4QBO A;  1GEF A;  2WCZ A;  3IEY B;  1A79 A;  3DNX A;  1ZP7 A;  1Y1O A;  2OKF A;  1IPI A;  1T0F A;  2WIZ A;  4FZ2 A;  2VLD A;  5FDK A;  1OB9 A;  2EO0 A;  2WCW A;  2GW6 A;  4TKD A;  1RLV A; 
#chains in the Genus database with same CATH topology
 2OST A;  2JJQ A;  1NNE A;  4ZQU A;  3THX A;  4TKK A;  3P1Z A;  3P1Y A;  3THX B;  1WBD A;  2O8B A;  1R0V A;  2O8B B;  1F1Z A;  2INB A;  2WCZ A;  2FLC A;  3DNX A;  2OKF A;  1OH5 A;  4E6Z A;  2O8D B;  2VLD A;  5FDK A;  1FW6 A;  2O8C A;  2WCW A;  1OH8 A;  1W7A A;  2GJW A;  2O8C B;  3FOV A;  4QBN A;  2CV8 A;  1HH1 A;  4DAV A;  2FCO A;  4DA2 A;  4EV1 A;  4G6V A;  3ZLJ A;  1OH6 A;  2W8M A;  4QBO A;  4G6U A;  2O8E A;  2O8D A;  1IPI A;  1T0F A;  2O8E B;  2CZR A;  2EO0 A;  2Z0R A;  3AJV A;  2O8F B;  1Y88 A;  1YNM A;  3BT7 A;  2WJ0 A;  3AJV B;  3THW B;  1OB8 A;  2FZ4 A;  1RZN A;  1OH7 A;  2WTU A;  3IF0 X;  1EWQ A;  4QBL A;  2WIW A;  2DBS A;  2FL3 A;  1NG9 A;  1GEF A;  3IEY B;  1UWV A;  2VS1 A;  2IXS A;  2WIZ A;  4LQE A;  4DAP A;  1OB9 A;  2O8F A;  2FWR A;  3THY B;  3THW A;  2ZYZ A;  2FKH B;  1XMX A;  2ZYZ B;  3P1Z B;  2BH2 A;  3IEY A;  1R11 A;  1WBB A;  1A79 A;  1ZP7 A;  1WB9 A;  1Y1O A;  1E3M A;  3K0S A;  4FZ2 A;  3THY A;  2GW6 A;  4TKD A;  1RLV A;  2FKC A; 
#chains in the Genus database with same CATH homology
 3AJV A;  2OST A;  1Y88 A;  2GJW A;  1YNM A;  3FOV A;  2JJQ A;  3BT7 A;  2WJ0 A;  4QBN A;  3AJV B;  2ZYZ A;  2CV8 A;  1OB8 A;  4ZQU A;  1HH1 A;  2Z0R A;  1RZN A;  4TKK A;  4DAV A;  2FCO A;  3P1Z A;  2ZYZ B;  1XMX A;  4DA2 A;  2FKH B;  4EV1 A;  4G6V A;  3P1Y A;  3P1Z B;  2W8M A;  3IF0 X;  4QBL A;  2WIW A;  2DBS A;  2FL3 A;  3IEY A;  1R0V A;  2BH2 A;  2INB A;  1F1Z A;  1R11 A;  4QBO A;  1GEF A;  2WCZ A;  3IEY B;  1UWV A;  4G6U A;  2FLC A;  1A79 A;  3DNX A;  2VS1 A;  1ZP7 A;  1Y1O A;  2IXS A;  2OKF A;  1IPI A;  1T0F A;  4E6Z A;  2CZR A;  2WIZ A;  4LQE A;  4FZ2 A;  2VLD A;  4DAP A;  5FDK A;  1OB9 A;  2EO0 A;  2WCW A;  2GW6 A;  4TKD A;  1RLV A;  2FKC A; 
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