3P1ZB

Crystal structure of the aperopyrum pernix rna splicing endonuclease
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDHAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 46
structure length 180
sequence length 180
chains with identical sequence D, F, H, J, L
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3p1zB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1zB02
4TKDA 4QBOA 2OKFA 1XMXA 1F1ZA 1HH1A 1T0FA 2VLDA 2CV8A 3IEYA 3FOVA 5FDKA 2WIZA 1A79A 2ZYZA 4QBNA 1Y1OA 2GW6A 3AJVA 1ZP7A 1RZNA 4FZ2A 1OB8A 2ZYZB 2WCWA 3AJVB 3P1ZA 4TKKA 1OB9A 3P1ZB 3DNXA 1R0VA 1R11A 2INBA 1GEFA 4QBLA 2WIWA 1IPIA 2WJ0A 1Y88A 2FCOA 2OSTA 1RLVA 2WCZA 2GJWA 2EO0A 3P1YA
chains in the Genus database with same CATH superfamily
2O8DA 2OKFA 1T0FA 1HH1A 2VLDA 2VS1A 2WIZA 4LQEA 1W7AA 4DAVA 3P1ZA 1R11A 2INBA 1OH7A 2O8FA 1IPIA 2O8EB 2IXSA 2Z0RA 1WBDA 2WCZA 4TKDA 1FW6A 2WTUA 5FDKA 3IEYA 2O8BB 2ZYZA 4QBNA 1Y1OA 2GW6A 3K0SA 1RZNA 2WCWA 4EV1A 2FKCA 3AJVB 1WB9A 1OH8A 1UWVA 3BT7A 3THYB 1E3MA 4G6VA 3DNXA 2GJWA 2WIWA 1OH5A 2W8MA 1NG9A 1EWQA 2O8CB 2EO0A 2O8BA 1OH6A 4QBOA 2FZ4A 3FOVA 1WBBA 2O8DB 2FL3A 4FZ2A 3THWB 1OB8A 4DA2A 3THYA 1NNEA 3THXB 4TKKA 1OB9A 3P1ZB 3ZLJA 4E6ZA 4DAPA 2O8EA 2JJQA 1RLVA 1YNMA 1XMXA 1F1ZA 2CV8A 2FLCA 3THWA 3IEYB 1A79A 4G6UA 3AJVA 3THXA 1ZP7A 2FWRA 2ZYZB 3IF0X 2BH2A 2DBSA 4ZQUA 1R0VA 1GEFA 4QBLA 2O8CA 2WJ0A 2CZRA 1Y88A 2FCOA 2OSTA 2FKHB 2O8FB 3P1YA
chains in the Genus database with same CATH topology
4TKDA 4QBOA 2OKFA 1XMXA 1F1ZA 1HH1A 1T0FA 2VLDA 2CV8A 3IEYA 2VS1A 3FOVA 5FDKA 2WIZA 2FLCA 4LQEA 2FL3A 3IEYB 1A79A 2ZYZA 4QBNA 1Y1OA 2GW6A 4G6UA 4DAVA 3AJVA 1ZP7A 1RZNA 4FZ2A 1OB8A 2ZYZB 4DA2A 2WCWA 4EV1A 2FKCA 3AJVB 3IF0X 3P1ZA 1UWVA 2BH2A 3BT7A 2DBSA 4TKKA 4G6VA 1OB9A 3P1ZB 3DNXA 4ZQUA 1R0VA 4E6ZA 1R11A 4DAPA 2INBA 1GEFA 4QBLA 2WIWA 2W8MA 1IPIA 2WJ0A 2JJQA 2CZRA 2IXSA 2Z0RA 1Y88A 2FCOA 2FKHB 2OSTA 1RLVA 2WCZA 2GJWA 2EO0A 1YNMA 3P1YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TKD A;  4QBO A;  2OKF A;  1XMX A;  1F1Z A;  1HH1 A;  1T0F A;  2VLD A;  2CV8 A;  3IEY A;  3FOV A;  5FDK A;  2WIZ A;  1A79 A;  2ZYZ A;  4QBN A;  1Y1O A;  2GW6 A;  3AJV A;  1ZP7 A;  1RZN A;  4FZ2 A;  1OB8 A;  2ZYZ B;  2WCW A;  3AJV B;  3P1Z A;  4TKK A;  1OB9 A;  3P1Z B;  3DNX A;  1R0V A;  1R11 A;  2INB A;  1GEF A;  4QBL A;  2WIW A;  1IPI A;  2WJ0 A;  1Y88 A;  2FCO A;  2OST A;  1RLV A;  2WCZ A;  2GJW A;  2EO0 A;  3P1Y A; 
#chains in the Genus database with same CATH topology
 2O8D A;  2OKF A;  1T0F A;  1HH1 A;  2VLD A;  2VS1 A;  2WIZ A;  4LQE A;  1W7A A;  4DAV A;  3P1Z A;  1R11 A;  2INB A;  1OH7 A;  2O8F A;  1IPI A;  2O8E B;  2IXS A;  2Z0R A;  1WBD A;  2WCZ A;  4TKD A;  1FW6 A;  2WTU A;  5FDK A;  3IEY A;  2O8B B;  2ZYZ A;  4QBN A;  1Y1O A;  2GW6 A;  3K0S A;  1RZN A;  2WCW A;  4EV1 A;  2FKC A;  3AJV B;  1WB9 A;  1OH8 A;  1UWV A;  3BT7 A;  3THY B;  1E3M A;  4G6V A;  3DNX A;  2GJW A;  2WIW A;  1OH5 A;  2W8M A;  1NG9 A;  1EWQ A;  2O8C B;  2EO0 A;  2O8B A;  1OH6 A;  4QBO A;  2FZ4 A;  3FOV A;  1WBB A;  2O8D B;  2FL3 A;  4FZ2 A;  3THW B;  1OB8 A;  4DA2 A;  3THY A;  1NNE A;  3THX B;  4TKK A;  1OB9 A;  3P1Z B;  3ZLJ A;  4E6Z A;  4DAP A;  2O8E A;  2JJQ A;  1RLV A;  1YNM A;  1XMX A;  1F1Z A;  2CV8 A;  2FLC A;  3THW A;  3IEY B;  1A79 A;  4G6U A;  3AJV A;  3THX A;  1ZP7 A;  2FWR A;  2ZYZ B;  3IF0 X;  2BH2 A;  2DBS A;  4ZQU A;  1R0V A;  1GEF A;  4QBL A;  2O8C A;  2WJ0 A;  2CZR A;  1Y88 A;  2FCO A;  2OST A;  2FKH B;  2O8F B;  3P1Y A; 
#chains in the Genus database with same CATH homology
 4TKD A;  4QBO A;  2OKF A;  1XMX A;  1F1Z A;  1HH1 A;  1T0F A;  2VLD A;  2CV8 A;  3IEY A;  2VS1 A;  3FOV A;  5FDK A;  2WIZ A;  2FLC A;  4LQE A;  2FL3 A;  3IEY B;  1A79 A;  2ZYZ A;  4QBN A;  1Y1O A;  2GW6 A;  4G6U A;  4DAV A;  3AJV A;  1ZP7 A;  1RZN A;  4FZ2 A;  1OB8 A;  2ZYZ B;  4DA2 A;  2WCW A;  4EV1 A;  2FKC A;  3AJV B;  3IF0 X;  3P1Z A;  1UWV A;  2BH2 A;  3BT7 A;  2DBS A;  4TKK A;  4G6V A;  1OB9 A;  3P1Z B;  3DNX A;  4ZQU A;  1R0V A;  4E6Z A;  1R11 A;  4DAP A;  2INB A;  1GEF A;  4QBL A;  2WIW A;  2W8M A;  1IPI A;  2WJ0 A;  2JJQ A;  2CZR A;  2IXS A;  2Z0R A;  1Y88 A;  2FCO A;  2FKH B;  2OST A;  1RLV A;  2WCZ A;  2GJW A;  2EO0 A;  1YNM A;  3P1Y A; 
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