3P1ZB

Crystal structure of the aperopyrum pernix rna splicing endonuclease
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
180
structure length
180
Chain Sequence
PIKASGVLIGDSVLVTDVEQARSLYSCGYYGQPLDVEKPRGADFEGPLRLSLIESLYLAEKGVLEVAKPDGSSVGVEDLRTAVRGNPRFSMLYNIYRDLRERGFVVRSGLKFGSDFAVYRLGPGIDHAPFIVHAYSPEDNIDPVEIVRAGRLSHSVRKKFVFAVTRGGDVSYLMIDWFRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Aeropyrum pernix
molecule keywords Putative uncharacterized protein
total genus 46
structure length 180
sequence length 180
chains with identical sequence D, F, H, J, L
ec nomenclature ec 4.6.1.16: tRNA-intron lyase.
pdb deposition date 2010-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
B PF02778 tRNA_int_endo_N tRNA intron endonuclease, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 3p1zB01
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 3p1zB02
2GW6A 1XMXA 2EO0A 2CV8A 1HH1A 4TKDA 3P1ZA 1R0VA 4FZ2A 3AJVB 2INBA 1ZP7A 5FDKA 2WJ0A 1T0FA 2OKFA 2FCOA 2WCWA 2OSTA 1RLVA 1A79A 1GEFA 3DNXA 2WIWA 2WCZA 4QBNA 3AJVA 1OB8A 2ZYZB 1IPIA 4QBOA 1Y1OA 1F1ZA 1OB9A 3P1YA 2VLDA 3P1ZB 1Y88A 3IEYA 4TKKA 4QBLA 2WIZA 1R11A 3FOVA 2GJWA 2ZYZA 1RZNA
chains in the Genus database with same CATH superfamily
1XMXA 2EO0A 2CV8A 4TKDA 2O8BA 4DAPA 4FZ2A 3THXB 3BT7A 1YNMA 2OKFA 2WCWA 3IEYB 1GEFA 1OH8A 3DNXA 2WIWA 3AJVA 3THYA 1OB9A 1R11A 2O8DB 2CZRA 3FOVA 2GJWA 2FKCA 2GW6A 1WBBA 1OH7A 1HH1A 2WTUA 3P1ZA 3THWA 2W8MA 2O8FB 1T0FA 2IXSA 2FCOA 1EWQA 2FKHB 1WBDA 3THXA 2FLCA 4QBOA 1F1ZA 4G6VA 3P1YA 4LQEA 1Y88A 3IEYA 3IF0X 4QBLA 4E6ZA 2FZ4A 2FL3A 1RZNA 2VS1A 2JJQA 4DA2A 1R0VA 1ZP7A 3ZLJA 1OH6A 2O8CB 1UWVA 2DBSA 1RLVA 2WCZA 2O8FA 2O8EB 2ZYZB 1IPIA 4DAVA 4EV1A 2O8BB 2VLDA 4TKKA 2WIZA 4ZQUA 1E3MA 2BH2A 3AJVB 2INBA 5FDKA 1W7AA 2WJ0A 2O8DA 3THYB 2OSTA 1A79A 2FWRA 1NNEA 1OH5A 4QBNA 3K0SA 1WB9A 1OB8A 2O8CA 2Z0RA 1Y1OA 3P1ZB 3THWB 1FW6A 1NG9A 2O8EA 4G6UA 2ZYZA
chains in the Genus database with same CATH topology
2GW6A 1XMXA 2EO0A 2CV8A 1HH1A 2VS1A 4TKDA 4ZQUA 3P1ZA 2JJQA 4DA2A 2BH2A 2W8MA 1R0VA 4FZ2A 3AJVB 2INBA 4DAPA 1ZP7A 5FDKA 1YNMA 2WJ0A 1T0FA 3BT7A 2OKFA 2IXSA 2FCOA 1UWVA 2WCWA 2FKHB 2OSTA 2DBSA 1RLVA 1A79A 3IEYB 1GEFA 3DNXA 2WIWA 2WCZA 4QBNA 3AJVA 1OB8A 2ZYZB 1IPIA 2Z0RA 2FLCA 4QBOA 1Y1OA 4DAVA 1F1ZA 1OB9A 3P1YA 4G6VA 2VLDA 3P1ZB 1Y88A 4LQEA 4EV1A 3IEYA 3IF0X 4QBLA 4TKKA 2WIZA 2FKCA 1R11A 4E6ZA 2CZRA 3FOVA 2GJWA 2ZYZA 4G6UA 2FL3A 1RZNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GW6 A;  1XMX A;  2EO0 A;  2CV8 A;  1HH1 A;  4TKD A;  3P1Z A;  1R0V A;  4FZ2 A;  3AJV B;  2INB A;  1ZP7 A;  5FDK A;  2WJ0 A;  1T0F A;  2OKF A;  2FCO A;  2WCW A;  2OST A;  1RLV A;  1A79 A;  1GEF A;  3DNX A;  2WIW A;  2WCZ A;  4QBN A;  3AJV A;  1OB8 A;  2ZYZ B;  1IPI A;  4QBO A;  1Y1O A;  1F1Z A;  1OB9 A;  3P1Y A;  2VLD A;  3P1Z B;  1Y88 A;  3IEY A;  4TKK A;  4QBL A;  2WIZ A;  1R11 A;  3FOV A;  2GJW A;  2ZYZ A;  1RZN A; 
#chains in the Genus database with same CATH topology
 1XMX A;  2EO0 A;  2CV8 A;  4TKD A;  2O8B A;  4DAP A;  4FZ2 A;  3THX B;  3BT7 A;  1YNM A;  2OKF A;  2WCW A;  3IEY B;  1GEF A;  1OH8 A;  3DNX A;  2WIW A;  3AJV A;  3THY A;  1OB9 A;  1R11 A;  2O8D B;  2CZR A;  3FOV A;  2GJW A;  2FKC A;  2GW6 A;  1WBB A;  1OH7 A;  1HH1 A;  2WTU A;  3P1Z A;  3THW A;  2W8M A;  2O8F B;  1T0F A;  2IXS A;  2FCO A;  1EWQ A;  2FKH B;  1WBD A;  3THX A;  2FLC A;  4QBO A;  1F1Z A;  4G6V A;  3P1Y A;  4LQE A;  1Y88 A;  3IEY A;  3IF0 X;  4QBL A;  4E6Z A;  2FZ4 A;  2FL3 A;  1RZN A;  2VS1 A;  2JJQ A;  4DA2 A;  1R0V A;  1ZP7 A;  3ZLJ A;  1OH6 A;  2O8C B;  1UWV A;  2DBS A;  1RLV A;  2WCZ A;  2O8F A;  2O8E B;  2ZYZ B;  1IPI A;  4DAV A;  4EV1 A;  2O8B B;  2VLD A;  4TKK A;  2WIZ A;  4ZQU A;  1E3M A;  2BH2 A;  3AJV B;  2INB A;  5FDK A;  1W7A A;  2WJ0 A;  2O8D A;  3THY B;  2OST A;  1A79 A;  2FWR A;  1NNE A;  1OH5 A;  4QBN A;  3K0S A;  1WB9 A;  1OB8 A;  2O8C A;  2Z0R A;  1Y1O A;  3P1Z B;  3THW B;  1FW6 A;  1NG9 A;  2O8E A;  4G6U A;  2ZYZ A; 
#chains in the Genus database with same CATH homology
 2GW6 A;  1XMX A;  2EO0 A;  2CV8 A;  1HH1 A;  2VS1 A;  4TKD A;  4ZQU A;  3P1Z A;  2JJQ A;  4DA2 A;  2BH2 A;  2W8M A;  1R0V A;  4FZ2 A;  3AJV B;  2INB A;  4DAP A;  1ZP7 A;  5FDK A;  1YNM A;  2WJ0 A;  1T0F A;  3BT7 A;  2OKF A;  2IXS A;  2FCO A;  1UWV A;  2WCW A;  2FKH B;  2OST A;  2DBS A;  1RLV A;  1A79 A;  3IEY B;  1GEF A;  3DNX A;  2WIW A;  2WCZ A;  4QBN A;  3AJV A;  1OB8 A;  2ZYZ B;  1IPI A;  2Z0R A;  2FLC A;  4QBO A;  1Y1O A;  4DAV A;  1F1Z A;  1OB9 A;  3P1Y A;  4G6V A;  2VLD A;  3P1Z B;  1Y88 A;  4LQE A;  4EV1 A;  3IEY A;  3IF0 X;  4QBL A;  4TKK A;  2WIZ A;  2FKC A;  1R11 A;  4E6Z A;  2CZR A;  3FOV A;  2GJW A;  2ZYZ A;  4G6U A;  2FL3 A;  1RZN A; 
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