3S1BV

The development of peptide-based tools for the analysis of angiogenesis
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
96
structure length
96
Chain Sequence
HEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The development of Peptide-based tools for the analysis of angiogenesis.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Vascular endothelial growth factor A
total genus 15
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2011-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
V PF00341 PDGF PDGF/VEGF domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 3s1bV00
3BMPA 1B8KA 1PDGA 4ZFFC 2GH0C 5HI5A 4HQXA 1WAQA 4UI1A 1BTGA 1KATW 3HH2A 3E07A 1B98A 4MQWA 1WQ8A 4EDXV 3SEKB 1REWA 1M4UL 2XACA 3FUBB 5AEJA 4EC7A 1HRPB 3EO1C 4AY9A 1TGJA 3IJ2A 2VWEA 3V2AA 2H64A 2V5EB 4QHUC 2R53A 3S1BV 5HI3A 1B8MB 1M4UA 2XV7A 4MPLA 4FAOA 5BQ8A 1BETA 4GLSE 2TGIA 5BQBA 3KFDA 5HHDA 1ES7A 1E9JA 2IFGE 1WQ9B 3QB4A 4UHZA 1LXIA 4KZNA 3BUKA 2QJBA 1FL7B 2X1WA 3V6BA 1KLAA 4BV4L 2ASKA 2VXSA 2KD3A 1NT3A 2VPFA 2X1XE 4WPBA 4LXSJ 5BQEB 2ARVA 5F3BC 1HCNB 1TZIV 3P9WA 3QTKA 1QFWA 2GYRA 4UI0A 4EAXA 2H62A 4LXRJ 5F3HI 5HHXA 3S1KV 1BNDA 5BPUA 1HCFA 5E4GA 1TGKA 2QJAA 5HK5A 1HD4A 1AGQA 1VPFA 4EFVA 3EVSB 2ARPA 4MQWB 1VPPV 4X1JA 2B0UA 2P6AA 1BJ1V 1BMPA 2BHKA 1AOCA 2QJ9A 3BK3A 3MJGA 5FV2V 4AY9B 1QTYR 1REUA 1MKGA 1S4YB 4HQUA 1WQ9A 1ZKZA 2C7WA 4ZBNA 3B4VA 1SGFB 1CZ8V 4UHYA 1RV6V 1DZ7A 1KLCA 1HRPA 2R52A 4HSAA 5BQCA 4EDWV 1XWDB 4YCIC 1FLTV 1FZVA 5BQ8B 1MJVA 4N1DA 5FV1V 3BDYV 1B8MA 5HK5E 5HHVA 4QAFC 4MIDA 1WWWV 2QCWA 4YCGC 1TZHV 1LX5A 4GLNE 5HI4A 2QCQA 2GYZA 1TFGA 4KV5A 1FL7A 2GNNA 1NYUB 1SG1A 5JZ7A 1QFWB 4UI2B 5BQ8D 3MJKA 1NYSB 1BNDB 1MKKA 1KTZA 2GOOA 2FJGV 2QR0C 2FJHV 1JPYA 4KXZA 5BQEA 3JVFA 5HHCA 1HCNA 4XPJA 1XWDA 3RJRA 4HR9A 4QCIC 2PJYA
chains in the Genus database with same CATH superfamily
3BMPA 1B8KA 1PDGA 4ZFFC 2GH0C 5HI5A 4HQXA 1WAQA 4UI1A 1BTGA 1KATW 3HH2A 3E07A 1B98A 4MQWA 1WQ8A 4EDXV 3SEKB 1REWA 1M4UL 2XACA 3FUBB 5AEJA 4EC7A 1HRPB 3EO1C 4AY9A 1TGJA 3IJ2A 2VWEA 3V2AA 2H64A 2V5EB 4QHUC 2R53A 3S1BV 5HI3A 1B8MB 1M4UA 2XV7A 4MPLA 4FAOA 5BQ8A 1BETA 4GLSE 2TGIA 5BQBA 3KFDA 5HHDA 1ES7A 1E9JA 2IFGE 1WQ9B 3QB4A 4UHZA 1LXIA 4KZNA 3BUKA 2QJBA 1FL7B 2X1WA 3V6BA 1KLAA 4BV4L 2ASKA 2VXSA 2KD3A 1NT3A 2VPFA 2X1XE 4WPBA 4LXSJ 5BQEB 2ARVA 5F3BC 1HCNB 1TZIV 3P9WA 3QTKA 1QFWA 2GYRA 4UI0A 4EAXA 2H62A 4LXRJ 5F3HI 5HHXA 3S1KV 1BNDA 5BPUA 1HCFA 5E4GA 1TGKA 2QJAA 5HK5A 1HD4A 1AGQA 1VPFA 4EFVA 3EVSB 2ARPA 4MQWB 1VPPV 4X1JA 2B0UA 2P6AA 1BJ1V 1BMPA 2BHKA 1AOCA 2QJ9A 3BK3A 3MJGA 5FV2V 4AY9B 1QTYR 1REUA 1MKGA 1S4YB 4HQUA 1WQ9A 1ZKZA 2C7WA 4ZBNA 3B4VA 1SGFB 1CZ8V 4UHYA 1RV6V 1DZ7A 1KLCA 1HRPA 2R52A 4HSAA 5BQCA 4EDWV 1XWDB 4YCIC 1FLTV 1FZVA 5BQ8B 1MJVA 4N1DA 5FV1V 3BDYV 1B8MA 5HK5E 5HHVA 4QAFC 4MIDA 1WWWV 2QCWA 4YCGC 1TZHV 1LX5A 4GLNE 5HI4A 2QCQA 2GYZA 1TFGA 4KV5A 1FL7A 2GNNA 1NYUB 1SG1A 5JZ7A 1QFWB 4UI2B 5BQ8D 3MJKA 1NYSB 1BNDB 1MKKA 1KTZA 2GOOA 2FJGV 2QR0C 2FJHV 1JPYA 4KXZA 5BQEA 3JVFA 5HHCA 1HCNA 4XPJA 1XWDA 3RJRA 4HR9A 4QCIC 2PJYA
chains in the Genus database with same CATH topology
3BMPA 1B8KA 1PDGA 4ZFFC 2GH0C 5HI5A 4HQXA 1WAQA 4UI1A 1BTGA 1KATW 3HH2A 3E07A 1B98A 4MQWA 1WQ8A 4EDXV 3SEKB 1REWA 1M4UL 2XACA 3FUBB 5AEJA 4EC7A 1HRPB 3EO1C 4AY9A 1TGJA 3IJ2A 2VWEA 3V2AA 2H64A 2V5EB 4QHUC 2R53A 3S1BV 5HI3A 1B8MB 1M4UA 2XV7A 4MPLA 4FAOA 5BQ8A 1BETA 4GLSE 2TGIA 5BQBA 3KFDA 5HHDA 1ES7A 1E9JA 2IFGE 1WQ9B 3QB4A 4UHZA 1LXIA 4KZNA 3BUKA 2QJBA 1FL7B 2X1WA 3V6BA 1KLAA 4BV4L 2ASKA 2VXSA 2KD3A 1NT3A 2VPFA 2X1XE 4WPBA 4LXSJ 5BQEB 2ARVA 5F3BC 1HCNB 1TZIV 3P9WA 3QTKA 1QFWA 2GYRA 4UI0A 4EAXA 2H62A 4LXRJ 5F3HI 5HHXA 3S1KV 1BNDA 5BPUA 1HCFA 5E4GA 1TGKA 2QJAA 5HK5A 1HD4A 1AGQA 1VPFA 4EFVA 3EVSB 2ARPA 4MQWB 1VPPV 4X1JA 2B0UA 2P6AA 1BJ1V 1BMPA 2BHKA 1AOCA 2QJ9A 3BK3A 3MJGA 5FV2V 4AY9B 1QTYR 1REUA 1MKGA 1S4YB 4HQUA 1WQ9A 1ZKZA 2C7WA 4ZBNA 3B4VA 1SGFB 1CZ8V 4UHYA 1RV6V 1DZ7A 1KLCA 1HRPA 2R52A 4HSAA 5BQCA 4EDWV 1XWDB 4YCIC 1FLTV 1FZVA 5BQ8B 1MJVA 4N1DA 5FV1V 3BDYV 1B8MA 5HK5E 5HHVA 4QAFC 4MIDA 1WWWV 2QCWA 4YCGC 1TZHV 1LX5A 4GLNE 5HI4A 2QCQA 2GYZA 1TFGA 4KV5A 1FL7A 2GNNA 1NYUB 1SG1A 5JZ7A 1QFWB 4UI2B 5BQ8D 3MJKA 1NYSB 1BNDB 1MKKA 1KTZA 2GOOA 2FJGV 2QR0C 2FJHV 1JPYA 4KXZA 5BQEA 3JVFA 5HHCA 1HCNA 4XPJA 1XWDA 3RJRA 4HR9A 4QCIC 2PJYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BMP A;  1B8K A;  1PDG A;  4ZFF C;  2GH0 C;  5HI5 A;  4HQX A;  1WAQ A;  4UI1 A;  1BTG A;  1KAT W;  3HH2 A;  3E07 A;  1B98 A;  4MQW A;  1WQ8 A;  4EDX V;  3SEK B;  1REW A;  1M4U L;  2XAC A;  3FUB B;  5AEJ A;  4EC7 A;  1HRP B;  3EO1 C;  4AY9 A;  1TGJ A;  3IJ2 A;  2VWE A;  3V2A A;  2H64 A;  2V5E B;  4QHU C;  2R53 A;  3S1B V;  5HI3 A;  1B8M B;  1M4U A;  2XV7 A;  4MPL A;  4FAO A;  5BQ8 A;  1BET A;  4GLS E;  2TGI A;  5BQB A;  3KFD A;  5HHD A;  1ES7 A;  1E9J A;  2IFG E;  1WQ9 B;  3QB4 A;  4UHZ A;  1LXI A;  4KZN A;  3BUK A;  2QJB A;  1FL7 B;  2X1W A;  3V6B A;  1KLA A;  4BV4 L;  2ASK A;  2VXS A;  2KD3 A;  1NT3 A;  2VPF A;  2X1X E;  4WPB A;  4LXS J;  5BQE B;  2ARV A;  5F3B C;  1HCN B;  1TZI V;  3P9W A;  3QTK A;  1QFW A;  2GYR A;  4UI0 A;  4EAX A;  2H62 A;  4LXR J;  5F3H I;  5HHX A;  3S1K V;  1BND A;  5BPU A;  1HCF A;  5E4G A;  1TGK A;  2QJA A;  5HK5 A;  1HD4 A;  1AGQ A;  1VPF A;  4EFV A;  3EVS B;  2ARP A;  4MQW B;  1VPP V;  4X1J A;  2B0U A;  2P6A A;  1BJ1 V;  1BMP A;  2BHK A;  1AOC A;  2QJ9 A;  3BK3 A;  3MJG A;  5FV2 V;  4AY9 B;  1QTY R;  1REU A;  1MKG A;  1S4Y B;  4HQU A;  1WQ9 A;  1ZKZ A;  2C7W A;  4ZBN A;  3B4V A;  1SGF B;  1CZ8 V;  4UHY A;  1RV6 V;  1DZ7 A;  1KLC A;  1HRP A;  2R52 A;  4HSA A;  5BQC A;  4EDW V;  1XWD B;  4YCI C;  1FLT V;  1FZV A;  5BQ8 B;  1MJV A;  4N1D A;  5FV1 V;  3BDY V;  1B8M A;  5HK5 E;  5HHV A;  4QAF C;  4MID A;  1WWW V;  2QCW A;  4YCG C;  1TZH V;  1LX5 A;  4GLN E;  5HI4 A;  2QCQ A;  2GYZ A;  1TFG A;  4KV5 A;  1FL7 A;  2GNN A;  1NYU B;  1SG1 A;  5JZ7 A;  1QFW B;  4UI2 B;  5BQ8 D;  3MJK A;  1NYS B;  1BND B;  1MKK A;  1KTZ A;  2GOO A;  2FJG V;  2QR0 C;  2FJH V;  1JPY A;  4KXZ A;  5BQE A;  3JVF A;  5HHC A;  1HCN A;  4XPJ A;  1XWD A;  3RJR A;  4HR9 A;  4QCI C;  2PJY A; 
#chains in the Genus database with same CATH topology
 3BMP A;  1B8K A;  1PDG A;  4ZFF C;  2GH0 C;  5HI5 A;  4HQX A;  1WAQ A;  4UI1 A;  1BTG A;  1KAT W;  3HH2 A;  3E07 A;  1B98 A;  4MQW A;  1WQ8 A;  4EDX V;  3SEK B;  1REW A;  1M4U L;  2XAC A;  3FUB B;  5AEJ A;  4EC7 A;  1HRP B;  3EO1 C;  4AY9 A;  1TGJ A;  3IJ2 A;  2VWE A;  3V2A A;  2H64 A;  2V5E B;  4QHU C;  2R53 A;  3S1B V;  5HI3 A;  1B8M B;  1M4U A;  2XV7 A;  4MPL A;  4FAO A;  5BQ8 A;  1BET A;  4GLS E;  2TGI A;  5BQB A;  3KFD A;  5HHD A;  1ES7 A;  1E9J A;  2IFG E;  1WQ9 B;  3QB4 A;  4UHZ A;  1LXI A;  4KZN A;  3BUK A;  2QJB A;  1FL7 B;  2X1W A;  3V6B A;  1KLA A;  4BV4 L;  2ASK A;  2VXS A;  2KD3 A;  1NT3 A;  2VPF A;  2X1X E;  4WPB A;  4LXS J;  5BQE B;  2ARV A;  5F3B C;  1HCN B;  1TZI V;  3P9W A;  3QTK A;  1QFW A;  2GYR A;  4UI0 A;  4EAX A;  2H62 A;  4LXR J;  5F3H I;  5HHX A;  3S1K V;  1BND A;  5BPU A;  1HCF A;  5E4G A;  1TGK A;  2QJA A;  5HK5 A;  1HD4 A;  1AGQ A;  1VPF A;  4EFV A;  3EVS B;  2ARP A;  4MQW B;  1VPP V;  4X1J A;  2B0U A;  2P6A A;  1BJ1 V;  1BMP A;  2BHK A;  1AOC A;  2QJ9 A;  3BK3 A;  3MJG A;  5FV2 V;  4AY9 B;  1QTY R;  1REU A;  1MKG A;  1S4Y B;  4HQU A;  1WQ9 A;  1ZKZ A;  2C7W A;  4ZBN A;  3B4V A;  1SGF B;  1CZ8 V;  4UHY A;  1RV6 V;  1DZ7 A;  1KLC A;  1HRP A;  2R52 A;  4HSA A;  5BQC A;  4EDW V;  1XWD B;  4YCI C;  1FLT V;  1FZV A;  5BQ8 B;  1MJV A;  4N1D A;  5FV1 V;  3BDY V;  1B8M A;  5HK5 E;  5HHV A;  4QAF C;  4MID A;  1WWW V;  2QCW A;  4YCG C;  1TZH V;  1LX5 A;  4GLN E;  5HI4 A;  2QCQ A;  2GYZ A;  1TFG A;  4KV5 A;  1FL7 A;  2GNN A;  1NYU B;  1SG1 A;  5JZ7 A;  1QFW B;  4UI2 B;  5BQ8 D;  3MJK A;  1NYS B;  1BND B;  1MKK A;  1KTZ A;  2GOO A;  2FJG V;  2QR0 C;  2FJH V;  1JPY A;  4KXZ A;  5BQE A;  3JVF A;  5HHC A;  1HCN A;  4XPJ A;  1XWD A;  3RJR A;  4HR9 A;  4QCI C;  2PJY A; 
#chains in the Genus database with same CATH homology
 3BMP A;  1B8K A;  1PDG A;  4ZFF C;  2GH0 C;  5HI5 A;  4HQX A;  1WAQ A;  4UI1 A;  1BTG A;  1KAT W;  3HH2 A;  3E07 A;  1B98 A;  4MQW A;  1WQ8 A;  4EDX V;  3SEK B;  1REW A;  1M4U L;  2XAC A;  3FUB B;  5AEJ A;  4EC7 A;  1HRP B;  3EO1 C;  4AY9 A;  1TGJ A;  3IJ2 A;  2VWE A;  3V2A A;  2H64 A;  2V5E B;  4QHU C;  2R53 A;  3S1B V;  5HI3 A;  1B8M B;  1M4U A;  2XV7 A;  4MPL A;  4FAO A;  5BQ8 A;  1BET A;  4GLS E;  2TGI A;  5BQB A;  3KFD A;  5HHD A;  1ES7 A;  1E9J A;  2IFG E;  1WQ9 B;  3QB4 A;  4UHZ A;  1LXI A;  4KZN A;  3BUK A;  2QJB A;  1FL7 B;  2X1W A;  3V6B A;  1KLA A;  4BV4 L;  2ASK A;  2VXS A;  2KD3 A;  1NT3 A;  2VPF A;  2X1X E;  4WPB A;  4LXS J;  5BQE B;  2ARV A;  5F3B C;  1HCN B;  1TZI V;  3P9W A;  3QTK A;  1QFW A;  2GYR A;  4UI0 A;  4EAX A;  2H62 A;  4LXR J;  5F3H I;  5HHX A;  3S1K V;  1BND A;  5BPU A;  1HCF A;  5E4G A;  1TGK A;  2QJA A;  5HK5 A;  1HD4 A;  1AGQ A;  1VPF A;  4EFV A;  3EVS B;  2ARP A;  4MQW B;  1VPP V;  4X1J A;  2B0U A;  2P6A A;  1BJ1 V;  1BMP A;  2BHK A;  1AOC A;  2QJ9 A;  3BK3 A;  3MJG A;  5FV2 V;  4AY9 B;  1QTY R;  1REU A;  1MKG A;  1S4Y B;  4HQU A;  1WQ9 A;  1ZKZ A;  2C7W A;  4ZBN A;  3B4V A;  1SGF B;  1CZ8 V;  4UHY A;  1RV6 V;  1DZ7 A;  1KLC A;  1HRP A;  2R52 A;  4HSA A;  5BQC A;  4EDW V;  1XWD B;  4YCI C;  1FLT V;  1FZV A;  5BQ8 B;  1MJV A;  4N1D A;  5FV1 V;  3BDY V;  1B8M A;  5HK5 E;  5HHV A;  4QAF C;  4MID A;  1WWW V;  2QCW A;  4YCG C;  1TZH V;  1LX5 A;  4GLN E;  5HI4 A;  2QCQ A;  2GYZ A;  1TFG A;  4KV5 A;  1FL7 A;  2GNN A;  1NYU B;  1SG1 A;  5JZ7 A;  1QFW B;  4UI2 B;  5BQ8 D;  3MJK A;  1NYS B;  1BND B;  1MKK A;  1KTZ A;  2GOO A;  2FJG V;  2QR0 C;  2FJH V;  1JPY A;  4KXZ A;  5BQE A;  3JVF A;  5HHC A;  1HCN A;  4XPJ A;  1XWD A;  3RJR A;  4HR9 A;  4QCI C;  2PJY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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