4OQA | Genus

Total Genus 108

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	108
sequence length	481
structure length	456
Chain Sequence	AAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 456 atoms

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456 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Transferase/dna/transferase inhibitor
source organism	Homo sapiens
publication title	Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors. pubmed doi rcsb
molecule keywords	Poly [ADP-ribose] polymerase 1
total genus	108
structure length	456
sequence length	481
chains with identical sequence	F
ec nomenclature	ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date	2014-02-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
C	PF00644	PARP	Poly(ADP-ribose) polymerase catalytic domain
C	PF02877	PARP_reg	Poly(ADP-ribose) polymerase, regulatory domain
C	PF05406	WGR	WGR domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.142.10	Mainly Alpha	Up-down Bundle	Poly(ADP-ribose) Polymerase; domain 1	Poly(ADP-ribose) polymerase, regulatory domain	4oqaC03
2.20.140.10	Mainly Beta	Single Sheet	q64v53_bacfr protein fold	WGR domain	4oqaC01
3.90.228.10	Alpha Beta	Alpha-Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 3	Phosphoenolpyruvate Carboxykinase; domain 3	4oqaC02

4BU5A 4M7BA 3UDDA 4PMLA 4IUEA 4L7OA 4L7PA 4GV7A 4MT9A 4HLFA 4BUYA 4UVNA 4KZQA 5C5PA 4L7NA 4PNNA 4W5IA 3KCZA 4UVXA 5ETYA 4X52A 4TJYA 4BU8A 5ADQA 4KZLA 4PNMA 5DCZA 4U6AA 4L0SA 4OQBC 3MHKA 3KR7A 4GV4A 4L32A 4GV0A 3KJDA 2PQFA 4HLGA 4KZUA 4ZZXA 4TJWA 4BU9A 4PNSA 4L09A 4J3MA 3UA9A 4PNQA 4L2GA 4L6ZA 4J1ZA 4J22A 4L2KA 3GEYA 4MSKA 4N4TA 4BU3A 1A26A 1UK1A 4OPXC 4HMHA 4BUFA 2EOCA 4UW1A 4L34A 5AL1A 4UI3A 4BUUA 5AL2A 4L7RA 4UI6A 4PJTA 4BU6A 4UHGA 4F1LA 4L33A 4J21A 4UFUA 2X5YA 4L0TA 4BS4A 3C49A 5A00A 4BUDA 5ECEA 4HLKA 4PNLA 2RCWA 4TVJA 1EFYA 1GS0A 4TJUA 3P0PA 3SMIA 4I9IA 4BFPA 5EBTA 4RV6A 4PAXA 4L0VA 4BJBA 4L70A 4UVTA 5FPFA 4GV2A 4UNDA 4L6SA 4K4EA 4PY4A 4UI5A 4DVIA 4TK0A 4R6EA 3P0NA 4TKIA 4HKKA 4L10A 5ADRA 5AL3A 4F1QA 4DQYC 4BUSA 4TKGA 4PJVA 4HHYA 4HKNA 4UVOA 4HLMA 5FPGA 1UK0A 4L0IA 5C5RA 5LYHA 5AEHA 4UVUA 4BUAA 2RF5A 2CR9A 4OA7A 5ADSA 4J3LA 4UX4A 3UH2A 5C5QA 4UXBA 4OQAC 3PAXA 5ADTA 4PNTA 1PAXA 4MSGA 3KR8A 4UI8A 5LX6A 2RA8A 3CE0A 4UVWA 4L7LA 4K4FA 3L3LA 4N4VA 3FHBA 4HYFA 4BUIA 4TOSA 3GN7A 4UUHA 4W6EA 5AL4A 1WOKA 4ZZZA 5AKUA 4AVUA 4UFYA 4BU7A 3L3MA 4BUXA 4UI4A 4L7UA 4BJCA 4HKIA 3MHJA 4R5WA 4BUTA 4TORA 5AL5A 4HHZA 3W51A 4L31A 3UH4A 3P0QA 2PAXA 4HL5A 4AVWA 3SE2A 4UVSA 2RD6A 4BUWA 4LI6A 4PNRA 4UVYA 4BUEA 4UVPA 4W5SA 3SMJA 5LXPA 4UVLA 4KRSA 4XHUA 3GJWA 5AKWA 3C4HA 2PAWA 4TK5A 4TKFA 4UVVA 3U9YA 3U9HA 3BLJA 4LI7A 4LI8A 4L0BA 4F0EA 4BUVA 4UI7A 4UVZA 3HKVA 4BJ9A 3GOYA 4N3RA 4HLHA 4L2FA 4ZZYA
chains in the Genus database with same CATH superfamily

3UDDA 1AQ2A 4IUEA 2RKDA 4UVNA 4KZQA 4BHHB 5ETYA 4TJYA 5ADQA 4KZLA 5DCZA 3MHKA 4WPTA 3KJDA 4KZUA 4TJWA 4BU9A 2FAHA 4PNQA 4BGPA 4N4TA 4HMHA 4UW1A 4L7RA 4YW8A 4PJTA 3MOFA 4L0TA 4TJUA 2QF2A 4BJBA 4L70A 5FPFA 4L6SA 4PY4A 3P0NA 4TKIA 4L10A 4BUSA 4HHYA 4HLMA 5FPGA 1UK0A 4L0IA 5C5RA 5LYHA 4BUAA 5I67A 2RF5A 1YGGA 3UH2A 4GNQA 4UXBA 1YLHA 5FH3A 4WIEA 3MOEA 1PAXA 2OLRA 1K3DA 4WIUA 3CE0A 4K4FA 3FHBA 4BUXA 4HKIA 4R43A 4BUTA 4TORA 5AL5A 3P0QA 3SE2A 2RD6A 4BUWA 4W5SA 5AKWA 4KRSA 3C4HA 4TKFA 4LI8A 4L0BA 3HKVA 2RKAA 4M7BA 4PMLA 4L7OA 2PC9A 4HLFA 4BUYA 5C5PA 3KCZA 4UVXA 4BU8A 4PNMA 3DTBA 4L32A 4HLGA 4PNSA 4J3MA 4IJSA 4WOUA 4J1ZA 3GEYA 4MSKA 4OPXC 4BUFA 2EOCA 4L34A 4UI3A 4BUUA 4WL8A 2PY7X 4BU6A 2RK7A 4F1LA 4J21A 5A00A 4BUDA 4TVJA 4JNGA 3P0PA 2RKEA 1KHFA 4UNDA 2ZCIA 4UI5A 4TK0A 4R6EA 4F1QA 4DQYC 2OLQA 4GNMA 4WPUA 4GMZA 4UX4A 4OQAC 2QZYA 4MSGA 3KR8A 4UI8A 2RA8A 5FH2A 4N4VA 4HYFA 4TOSA 3GN7A 4BU7A 4W6EA 4AVUA 5FH0A 4UFYA 4BJCA 4L7UA 4WPVA 3W51A 3UH4A 2PAXA 4HL5A 4AVWA 1YTMA 2PXZX 4TK5A 4LI7A 4F0EA 3DT7A 4BUVA 4UVVA 4BU5A 1KHGA 4MT9A 4GV7A 4GNOA 4GMWA 4L7NA 3ZL9A 4W5IA 4X52A 4L0SA 4OQBC 3KR7A 4IDUA 2PQFA 4YWBA 3UA9A 4L2GA 4L6ZA 4J22A 5AL2A 4UI6A 1OS1A 4BS4A 3C49A 2FAFA 3DT4A 5ECEA 4HLKA 4PNLA 2RCWA 1GS0A 4I9IA 4BFPA 5EBTA 4RV6A 4PAXA 4L0VA 4UVTA 4GV2A 4DVIA 5AL3A 1AYLA 4RCGA 1J3BA 4UVOA 2HZSA 5AEHA 4UVUA 4OA7A 5ADSA 4J3LA 4J1GA 4IDXA 1KHEA 3PAXA 4J1JA 4PNTA 1KHBA 4GMMA 5FH5A 4UUHA 4YW9A 4L31A 4UVSA 4LI6A 1II2A 4GMUA 3ZLAA 5LXPA 4UVLA 3GJWA 2PAWA 3U9YA 3DT2A 4UI7A 4UVZA 4N3RA 4HLHA 4L2FA 1OENA 4L7PA 4PNNA 2QEYA 4U6AA 1NHXA 4GV4A 4GV0A 2QEWA 4GNPA 4ZZXA 4L09A 4L2KA 4BU3A 4OX2A 1A26A 1UK1A 5AL1A 5FH1A 1YVYA 4UHGA 4L33A 4UFUA 2QF1A 2X5YA 1EFYA 3SMIA 4K4EA 2RK8A 4HKKA 5ADRA 4TKGA 2HZMA 4PJVA 4GNLA 4HKNA 2CR9A 1M51A 5C5QA 1XKVA 5ADTA 4IDUB 5LX6A 4UVWA 4L7LA 2GMVA 3L3LA 4BUIA 4YWDA 5AL4A 1WOKA 4ZZZA 5AKUA 5FH4A 3L3MA 4UI4A 3MOHA 3MHJA 4R5WA 4HHZA 4PNRA 4UVYA 4BUEA 4UVPA 3SMJA 4XHUA 3U9HA 3BLJA 4BJ9A 3GOYA 1K3CA 4ZZYA
chains in the Genus database with same CATH topology

3UDDA 1AQ2A 4IUEA 2RKDA 4UVNA 4KZQA 5ETYA 4TJYA 5ADQA 4KZLA 5DCZA 3MHKA 4WPTA 3KJDA 4KZUA 4TJWA 4BU9A 2FAHA 4PNQA 4N4TA 4HMHA 4UW1A 4L7RA 4YW8A 4PJTA 3MOFA 4L0TA 4TJUA 2QF2A 4BJBA 4L70A 5FPFA 4L6SA 4PY4A 3P0NA 4TKIA 4L10A 4BUSA 4HHYA 4HLMA 5FPGA 1UK0A 4L0IA 5C5RA 5LYHA 4BUAA 5I67A 2RF5A 1YGGA 3UH2A 4GNQA 4UXBA 1YLHA 5FH3A 4WIEA 3MOEA 1PAXA 2OLRA 1K3DA 4WIUA 3CE0A 4K4FA 3FHBA 4BUXA 4HKIA 4R43A 4BUTA 4TORA 5AL5A 3P0QA 3SE2A 2RD6A 4BUWA 4W5SA 5AKWA 4KRSA 3C4HA 4TKFA 4LI8A 4L0BA 3HKVA 2RKAA 4M7BA 4PMLA 4L7OA 2PC9A 4HLFA 4BUYA 5C5PA 3KCZA 4UVXA 4BU8A 4PNMA 3DTBA 4L32A 4HLGA 4PNSA 4J3MA 4WOUA 4J1ZA 3GEYA 4MSKA 4OPXC 4BUFA 2EOCA 4L34A 4UI3A 4BUUA 4WL8A 2PY7X 4BU6A 2RK7A 4F1LA 4J21A 5A00A 4BUDA 4TVJA 3P0PA 2RKEA 1KHFA 4UNDA 2ZCIA 4UI5A 4TK0A 4R6EA 4F1QA 4DQYC 2OLQA 4GNMA 4WPUA 4GMZA 4UX4A 4OQAC 2QZYA 4MSGA 3KR8A 4UI8A 2RA8A 5FH2A 4N4VA 4HYFA 4TOSA 3GN7A 4BU7A 4W6EA 4AVUA 5FH0A 4UFYA 4BJCA 4L7UA 4WPVA 3W51A 3UH4A 2PAXA 4HL5A 4AVWA 1YTMA 2PXZX 4TK5A 4LI7A 4F0EA 3DT7A 4BUVA 4UVVA 4BU5A 1KHGA 4MT9A 4GV7A 4GNOA 4GMWA 4L7NA 4W5IA 4X52A 4L0SA 4OQBC 3KR7A 2PQFA 4YWBA 3UA9A 4L2GA 4L6ZA 4J22A 5AL2A 4UI6A 1OS1A 4BS4A 3C49A 2FAFA 3DT4A 5ECEA 4HLKA 4PNLA 2RCWA 1GS0A 4I9IA 4BFPA 5EBTA 4RV6A 4PAXA 4L0VA 4UVTA 4GV2A 4DVIA 5AL3A 1AYLA 4RCGA 1J3BA 4UVOA 5AEHA 4UVUA 4OA7A 5ADSA 4J3LA 1KHEA 3PAXA 4PNTA 1KHBA 4GMMA 5FH5A 4UUHA 4YW9A 4L31A 4UVSA 4LI6A 1II2A 4GMUA 5LXPA 4UVLA 3GJWA 2PAWA 3U9YA 3DT2A 4UI7A 4UVZA 4N3RA 4HLHA 4L2FA 1OENA 4L7PA 4PNNA 2QEYA 4U6AA 1NHXA 4GV4A 4GV0A 2QEWA 4GNPA 4ZZXA 4L09A 4L2KA 4BU3A 4OX2A 1A26A 1UK1A 5AL1A 5FH1A 1YVYA 4UHGA 4L33A 4UFUA 2QF1A 2X5YA 1EFYA 3SMIA 4K4EA 2RK8A 4HKKA 5ADRA 4TKGA 4PJVA 4GNLA 4HKNA 2CR9A 1M51A 5C5QA 1XKVA 5ADTA 5LX6A 4UVWA 4L7LA 2GMVA 3L3LA 4BUIA 4YWDA 5AL4A 1WOKA 4ZZZA 5AKUA 5FH4A 3L3MA 4UI4A 3MOHA 3MHJA 4R5WA 4HHZA 4PNRA 4UVYA 4BUEA 4UVPA 3SMJA 4XHUA 3U9HA 3BLJA 4BJ9A 3GOYA 1K3CA 4ZZYA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4BU5 A;  4M7B A;  3UDD A;  4PML A;  4IUE A;  4L7O A;  4L7P A;  4GV7 A;  4MT9 A;  4HLF A;  4BUY A;  4UVN A;  4KZQ A;  5C5P A;  4L7N A;  4PNN A;  4W5I A;  3KCZ A;  4UVX A;  5ETY A;  4X52 A;  4TJY A;  4BU8 A;  5ADQ A;  4KZL A;  4PNM A;  5DCZ A;  4U6A A;  4L0S A;  4OQB C;  3MHK A;  3KR7 A;  4GV4 A;  4L32 A;  4GV0 A;  3KJD A;  2PQF A;  4HLG A;  4KZU A;  4ZZX A;  4TJW A;  4BU9 A;  4PNS A;  4L09 A;  4J3M A;  3UA9 A;  4PNQ A;  4L2G A;  4L6Z A;  4J1Z A;  4J22 A;  4L2K A;  3GEY A;  4MSK A;  4N4T A;  4BU3 A;  1A26 A;  1UK1 A;  4OPX C;  4HMH A;  4BUF A;  2EOC A;  4UW1 A;  4L34 A;  5AL1 A;  4UI3 A;  4BUU A;  5AL2 A;  4L7R A;  4UI6 A;  4PJT A;  4BU6 A;  4UHG A;  4F1L A;  4L33 A;  4J21 A;  4UFU A;  2X5Y A;  4L0T A;  4BS4 A;  3C49 A;  5A00 A;  4BUD A;  5ECE A;  4HLK A;  4PNL A;  2RCW A;  4TVJ A;  1EFY A;  1GS0 A;  4TJU A;  3P0P A;  3SMI A;  4I9I A;  4BFP A;  5EBT A;  4RV6 A;  4PAX A;  4L0V A;  4BJB A;  4L70 A;  4UVT A;  5FPF A;  4GV2 A;  4UND A;  4L6S A;  4K4E A;  4PY4 A;  4UI5 A;  4DVI A;  4TK0 A;  4R6E A;  3P0N A;  4TKI A;  4HKK A;  4L10 A;  5ADR A;  5AL3 A;  4F1Q A;  4DQY C;  4BUS A;  4TKG A;  4PJV A;  4HHY A;  4HKN A;  4UVO A;  4HLM A;  5FPG A;  1UK0 A;  4L0I A;  5C5R A;  5LYH A;  5AEH A;  4UVU A;  4BUA A;  2RF5 A;  2CR9 A;  4OA7 A;  5ADS A;  4J3L A;  4UX4 A;  3UH2 A;  5C5Q A;  4UXB A;  4OQA C;  3PAX A;  5ADT A;  4PNT A;  1PAX A;  4MSG A;  3KR8 A;  4UI8 A;  5LX6 A;  2RA8 A;  3CE0 A;  4UVW A;  4L7L A;  4K4F A;  3L3L A;  4N4V A;  3FHB A;  4HYF A;  4BUI A;  4TOS A;  3GN7 A;  4UUH A;  4W6E A;  5AL4 A;  1WOK A;  4ZZZ A;  5AKU A;  4AVU A;  4UFY A;  4BU7 A;  3L3M A;  4BUX A;  4UI4 A;  4L7U A;  4BJC A;  4HKI A;  3MHJ A;  4R5W A;  4BUT A;  4TOR A;  5AL5 A;  4HHZ A;  3W51 A;  4L31 A;  3UH4 A;  3P0Q A;  2PAX A;  4HL5 A;  4AVW A;  3SE2 A;  4UVS A;  2RD6 A;  4BUW A;  4LI6 A;  4PNR A;  4UVY A;  4BUE A;  4UVP A;  4W5S A;  3SMJ A;  5LXP A;  4UVL A;  4KRS A;  4XHU A;  3GJW A;  5AKW A;  3C4H A;  2PAW A;  4TK5 A;  4TKF A;  4UVV A;  3U9Y A;  3U9H A;  3BLJ A;  4LI7 A;  4LI8 A;  4L0B A;  4F0E A;  4BUV A;  4UI7 A;  4UVZ A;  3HKV A;  4BJ9 A;  3GOY A;  4N3R A;  4HLH A;  4L2F A;  4ZZY A; 
#chains in the Genus database with same CATH topology
 3UDD A;  1AQ2 A;  4IUE A;  2RKD A;  4UVN A;  4KZQ A;  4BHH B;  5ETY A;  4TJY A;  5ADQ A;  4KZL A;  5DCZ A;  3MHK A;  4WPT A;  3KJD A;  4KZU A;  4TJW A;  4BU9 A;  2FAH A;  4PNQ A;  4BGP A;  4N4T A;  4HMH A;  4UW1 A;  4L7R A;  4YW8 A;  4PJT A;  3MOF A;  4L0T A;  4TJU A;  2QF2 A;  4BJB A;  4L70 A;  5FPF A;  4L6S A;  4PY4 A;  3P0N A;  4TKI A;  4L10 A;  4BUS A;  4HHY A;  4HLM A;  5FPG A;  1UK0 A;  4L0I A;  5C5R A;  5LYH A;  4BUA A;  5I67 A;  2RF5 A;  1YGG A;  3UH2 A;  4GNQ A;  4UXB A;  1YLH A;  5FH3 A;  4WIE A;  3MOE A;  1PAX A;  2OLR A;  1K3D A;  4WIU A;  3CE0 A;  4K4F A;  3FHB A;  4BUX A;  4HKI A;  4R43 A;  4BUT A;  4TOR A;  5AL5 A;  3P0Q A;  3SE2 A;  2RD6 A;  4BUW A;  4W5S A;  5AKW A;  4KRS A;  3C4H A;  4TKF A;  4LI8 A;  4L0B A;  3HKV A;  2RKA A;  4M7B A;  4PML A;  4L7O A;  2PC9 A;  4HLF A;  4BUY A;  5C5P A;  3KCZ A;  4UVX A;  4BU8 A;  4PNM A;  3DTB A;  4L32 A;  4HLG A;  4PNS A;  4J3M A;  4IJS A;  4WOU A;  4J1Z A;  3GEY A;  4MSK A;  4OPX C;  4BUF A;  2EOC A;  4L34 A;  4UI3 A;  4BUU A;  4WL8 A;  2PY7 X;  4BU6 A;  2RK7 A;  4F1L A;  4J21 A;  5A00 A;  4BUD A;  4TVJ A;  4JNG A;  3P0P A;  2RKE A;  1KHF A;  4UND A;  2ZCI A;  4UI5 A;  4TK0 A;  4R6E A;  4F1Q A;  4DQY C;  2OLQ A;  4GNM A;  4WPU A;  4GMZ A;  4UX4 A;  4OQA C;  2QZY A;  4MSG A;  3KR8 A;  4UI8 A;  2RA8 A;  5FH2 A;  4N4V A;  4HYF A;  4TOS A;  3GN7 A;  4BU7 A;  4W6E A;  4AVU A;  5FH0 A;  4UFY A;  4BJC A;  4L7U A;  4WPV A;  3W51 A;  3UH4 A;  2PAX A;  4HL5 A;  4AVW A;  1YTM A;  2PXZ X;  4TK5 A;  4LI7 A;  4F0E A;  3DT7 A;  4BUV A;  4UVV A;  4BU5 A;  1KHG A;  4MT9 A;  4GV7 A;  4GNO A;  4GMW A;  4L7N A;  3ZL9 A;  4W5I A;  4X52 A;  4L0S A;  4OQB C;  3KR7 A;  4IDU A;  2PQF A;  4YWB A;  3UA9 A;  4L2G A;  4L6Z A;  4J22 A;  5AL2 A;  4UI6 A;  1OS1 A;  4BS4 A;  3C49 A;  2FAF A;  3DT4 A;  5ECE A;  4HLK A;  4PNL A;  2RCW A;  1GS0 A;  4I9I A;  4BFP A;  5EBT A;  4RV6 A;  4PAX A;  4L0V A;  4UVT A;  4GV2 A;  4DVI A;  5AL3 A;  1AYL A;  4RCG A;  1J3B A;  4UVO A;  2HZS A;  5AEH A;  4UVU A;  4OA7 A;  5ADS A;  4J3L A;  4J1G A;  4IDX A;  1KHE A;  3PAX A;  4J1J A;  4PNT A;  1KHB A;  4GMM A;  5FH5 A;  4UUH A;  4YW9 A;  4L31 A;  4UVS A;  4LI6 A;  1II2 A;  4GMU A;  3ZLA A;  5LXP A;  4UVL A;  3GJW A;  2PAW A;  3U9Y A;  3DT2 A;  4UI7 A;  4UVZ A;  4N3R A;  4HLH A;  4L2F A;  1OEN A;  4L7P A;  4PNN A;  2QEY A;  4U6A A;  1NHX A;  4GV4 A;  4GV0 A;  2QEW A;  4GNP A;  4ZZX A;  4L09 A;  4L2K A;  4BU3 A;  4OX2 A;  1A26 A;  1UK1 A;  5AL1 A;  5FH1 A;  1YVY A;  4UHG A;  4L33 A;  4UFU A;  2QF1 A;  2X5Y A;  1EFY A;  3SMI A;  4K4E A;  2RK8 A;  4HKK A;  5ADR A;  4TKG A;  2HZM A;  4PJV A;  4GNL A;  4HKN A;  2CR9 A;  1M51 A;  5C5Q A;  1XKV A;  5ADT A;  4IDU B;  5LX6 A;  4UVW A;  4L7L A;  2GMV A;  3L3L A;  4BUI A;  4YWD A;  5AL4 A;  1WOK A;  4ZZZ A;  5AKU A;  5FH4 A;  3L3M A;  4UI4 A;  3MOH A;  3MHJ A;  4R5W A;  4HHZ A;  4PNR A;  4UVY A;  4BUE A;  4UVP A;  3SMJ A;  4XHU A;  3U9H A;  3BLJ A;  4BJ9 A;  3GOY A;  1K3C A;  4ZZY A; 
#chains in the Genus database with same CATH homology
 3UDD A;  1AQ2 A;  4IUE A;  2RKD A;  4UVN A;  4KZQ A;  5ETY A;  4TJY A;  5ADQ A;  4KZL A;  5DCZ A;  3MHK A;  4WPT A;  3KJD A;  4KZU A;  4TJW A;  4BU9 A;  2FAH A;  4PNQ A;  4N4T A;  4HMH A;  4UW1 A;  4L7R A;  4YW8 A;  4PJT A;  3MOF A;  4L0T A;  4TJU A;  2QF2 A;  4BJB A;  4L70 A;  5FPF A;  4L6S A;  4PY4 A;  3P0N A;  4TKI A;  4L10 A;  4BUS A;  4HHY A;  4HLM A;  5FPG A;  1UK0 A;  4L0I A;  5C5R A;  5LYH A;  4BUA A;  5I67 A;  2RF5 A;  1YGG A;  3UH2 A;  4GNQ A;  4UXB A;  1YLH A;  5FH3 A;  4WIE A;  3MOE A;  1PAX A;  2OLR A;  1K3D A;  4WIU A;  3CE0 A;  4K4F A;  3FHB A;  4BUX A;  4HKI A;  4R43 A;  4BUT A;  4TOR A;  5AL5 A;  3P0Q A;  3SE2 A;  2RD6 A;  4BUW A;  4W5S A;  5AKW A;  4KRS A;  3C4H A;  4TKF A;  4LI8 A;  4L0B A;  3HKV A;  2RKA A;  4M7B A;  4PML A;  4L7O A;  2PC9 A;  4HLF A;  4BUY A;  5C5P A;  3KCZ A;  4UVX A;  4BU8 A;  4PNM A;  3DTB A;  4L32 A;  4HLG A;  4PNS A;  4J3M A;  4WOU A;  4J1Z A;  3GEY A;  4MSK A;  4OPX C;  4BUF A;  2EOC A;  4L34 A;  4UI3 A;  4BUU A;  4WL8 A;  2PY7 X;  4BU6 A;  2RK7 A;  4F1L A;  4J21 A;  5A00 A;  4BUD A;  4TVJ A;  3P0P A;  2RKE A;  1KHF A;  4UND A;  2ZCI A;  4UI5 A;  4TK0 A;  4R6E A;  4F1Q A;  4DQY C;  2OLQ A;  4GNM A;  4WPU A;  4GMZ A;  4UX4 A;  4OQA C;  2QZY A;  4MSG A;  3KR8 A;  4UI8 A;  2RA8 A;  5FH2 A;  4N4V A;  4HYF A;  4TOS A;  3GN7 A;  4BU7 A;  4W6E A;  4AVU A;  5FH0 A;  4UFY A;  4BJC A;  4L7U A;  4WPV A;  3W51 A;  3UH4 A;  2PAX A;  4HL5 A;  4AVW A;  1YTM A;  2PXZ X;  4TK5 A;  4LI7 A;  4F0E A;  3DT7 A;  4BUV A;  4UVV A;  4BU5 A;  1KHG A;  4MT9 A;  4GV7 A;  4GNO A;  4GMW A;  4L7N A;  4W5I A;  4X52 A;  4L0S A;  4OQB C;  3KR7 A;  2PQF A;  4YWB A;  3UA9 A;  4L2G A;  4L6Z A;  4J22 A;  5AL2 A;  4UI6 A;  1OS1 A;  4BS4 A;  3C49 A;  2FAF A;  3DT4 A;  5ECE A;  4HLK A;  4PNL A;  2RCW A;  1GS0 A;  4I9I A;  4BFP A;  5EBT A;  4RV6 A;  4PAX A;  4L0V A;  4UVT A;  4GV2 A;  4DVI A;  5AL3 A;  1AYL A;  4RCG A;  1J3B A;  4UVO A;  5AEH A;  4UVU A;  4OA7 A;  5ADS A;  4J3L A;  1KHE A;  3PAX A;  4PNT A;  1KHB A;  4GMM A;  5FH5 A;  4UUH A;  4YW9 A;  4L31 A;  4UVS A;  4LI6 A;  1II2 A;  4GMU A;  5LXP A;  4UVL A;  3GJW A;  2PAW A;  3U9Y A;  3DT2 A;  4UI7 A;  4UVZ A;  4N3R A;  4HLH A;  4L2F A;  1OEN A;  4L7P A;  4PNN A;  2QEY A;  4U6A A;  1NHX A;  4GV4 A;  4GV0 A;  2QEW A;  4GNP A;  4ZZX A;  4L09 A;  4L2K A;  4BU3 A;  4OX2 A;  1A26 A;  1UK1 A;  5AL1 A;  5FH1 A;  1YVY A;  4UHG A;  4L33 A;  4UFU A;  2QF1 A;  2X5Y A;  1EFY A;  3SMI A;  4K4E A;  2RK8 A;  4HKK A;  5ADR A;  4TKG A;  4PJV A;  4GNL A;  4HKN A;  2CR9 A;  1M51 A;  5C5Q A;  1XKV A;  5ADT A;  5LX6 A;  4UVW A;  4L7L A;  2GMV A;  3L3L A;  4BUI A;  4YWD A;  5AL4 A;  1WOK A;  4ZZZ A;  5AKU A;  5FH4 A;  3L3M A;  4UI4 A;  3MOH A;  3MHJ A;  4R5W A;  4HHZ A;  4PNR A;  4UVY A;  4BUE A;  4UVP A;  3SMJ A;  4XHU A;  3U9H A;  3BLJ A;  4BJ9 A;  3GOY A;  1K3C A;  4ZZY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4OQAC

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations