4YCIC

Non-latent pro-bone morphogenetic protein 9
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
105
structure length
105
Chain Sequence
SHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of bone morphogenetic protein 9 procomplex.
pubmed doi rcsb
molecule tags Cytokine
source organism Mus musculus
molecule keywords Bone Morphogenetic Protein 9 Growth Factor Domain
total genus 22
structure length 105
sequence length 105
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-02-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00019 TGF_beta Transforming growth factor beta like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.90.10 Mainly Beta Ribbon Cystine Knot Cytokines, subunit B Cystine-knot cytokines 4yciC00
3SEKB 1TZHV 2ARVA 2H64A 5HI3A 1QFWA 5HHXA 1HCFA 1KLCA 4UI0A 1BNDA 4UHZA 1TGJA 4N1DA 4KXZA 1BTGA 2XV7A 5HHCA 5BQCA 3QB4A 1XWDA 1QFWB 5BQ8D 1BNDB 4AY9B 2VWEA 5HI4A 2BHKA 1HD4A 2GYZA 1WWWV 1BMPA 1B8MB 1NT3A 1MKKA 2H62A 2GNNA 1B98A 5HI5A 2KD3A 2IFGE 3IJ2A 5BQEB 3V2AA 3HH2A 4YCIC 2B0UA 1DZ7A 3KFDA 2R52A 3MJKA 5E4GA 2C7WA 2QJ9A 2R53A 3E07A 1SG1A 1JPYA 2X1XE 4GLNE 4QCIC 2XACA 4ZFFC 4UHYA 1ZKZA 3QTKA 4QAFC 1TGKA 4XPJA 5F3HI 3B4VA 3BMPA 1B8KA 4HQXA 1VPPV 1LX5A 1REUA 3JVFA 4FAOA 3BDYV 1FZVA 3EVSB 1TZIV 1XWDB 5HHDA 4KZNA 5F3BC 2VPFA 1QTYR 1AOCA 1HCNA 1KLAA 1KTZA 2QCWA 5BQ8A 3S1KV 1FLTV 2QJBA 2V5EB 1FL7A 4UI1A 4MIDA 4GLSE 1MJVA 2GYRA 1WQ9A 4ZBNA 4MQWA 1CZ8V 1WQ8A 4EDWV 3S1BV 4EFVA 2PJYA 1SGFB 5FV2V 1BETA 1ES7A 1HCNB 5BQ8B 4QHUC 4LXSJ 1FL7B 4EAXA 4BV4L 3FUBB 4HQUA 2FJHV 3MJGA 2GOOA 1RV6V 5FV1V 4HSAA 1BJ1V 4HR9A 1S4YB 4KV5A 5BQBA 4EDXV 2FJGV 1AGQA 3V6BA 2QCQA 4WPBA 5HHVA 1NYSB 1E9JA 2ASKA 4EC7A 5HK5A 4UI2B 1M4UL 4MPLA 4AY9A 5AEJA 5JZ7A 2TGIA 5BPUA 1HRPA 3RJRA 2X1WA 4X1JA 3BUKA 1B8MA 2VXSA 1WAQA 1TFGA 2QR0C 3P9WA 5BQEA 2P6AA 5HK5E 2GH0C 1LXIA 1HRPB 1WQ9B 1VPFA 4MQWB 4YCGC 2QJAA 1M4UA 1NYUB 3BK3A 1REWA 4LXRJ 1KATW 1PDGA 1MKGA 3EO1C 2ARPA
chains in the Genus database with same CATH superfamily
3SEKB 1TZHV 2ARVA 2H64A 5HI3A 1QFWA 5HHXA 1HCFA 1KLCA 4UI0A 1BNDA 4UHZA 1TGJA 4N1DA 4KXZA 1BTGA 2XV7A 5HHCA 5BQCA 3QB4A 1XWDA 1QFWB 5BQ8D 1BNDB 4AY9B 2VWEA 5HI4A 2BHKA 1HD4A 2GYZA 1WWWV 1BMPA 1B8MB 1NT3A 1MKKA 2H62A 2GNNA 1B98A 5HI5A 2KD3A 2IFGE 3IJ2A 5BQEB 3V2AA 3HH2A 4YCIC 2B0UA 1DZ7A 3KFDA 2R52A 3MJKA 5E4GA 2C7WA 2QJ9A 2R53A 3E07A 1SG1A 1JPYA 2X1XE 4GLNE 4QCIC 2XACA 4ZFFC 4UHYA 1ZKZA 3QTKA 4QAFC 1TGKA 4XPJA 5F3HI 3B4VA 3BMPA 1B8KA 4HQXA 1VPPV 1LX5A 1REUA 3JVFA 4FAOA 3BDYV 1FZVA 3EVSB 1TZIV 1XWDB 5HHDA 4KZNA 5F3BC 2VPFA 1QTYR 1AOCA 1HCNA 1KLAA 1KTZA 2QCWA 5BQ8A 3S1KV 1FLTV 2QJBA 2V5EB 1FL7A 4UI1A 4MIDA 4GLSE 1MJVA 2GYRA 1WQ9A 4ZBNA 4MQWA 1CZ8V 1WQ8A 4EDWV 3S1BV 4EFVA 2PJYA 1SGFB 5FV2V 1BETA 1ES7A 1HCNB 5BQ8B 4QHUC 4LXSJ 1FL7B 4EAXA 4BV4L 3FUBB 4HQUA 2FJHV 3MJGA 2GOOA 1RV6V 5FV1V 4HSAA 1BJ1V 4HR9A 1S4YB 4KV5A 5BQBA 4EDXV 2FJGV 1AGQA 3V6BA 2QCQA 4WPBA 5HHVA 1NYSB 1E9JA 2ASKA 4EC7A 5HK5A 4UI2B 1M4UL 4MPLA 4AY9A 5AEJA 5JZ7A 2TGIA 5BPUA 1HRPA 3RJRA 2X1WA 4X1JA 3BUKA 1B8MA 2VXSA 1WAQA 1TFGA 2QR0C 3P9WA 5BQEA 2P6AA 5HK5E 2GH0C 1LXIA 1HRPB 1WQ9B 1VPFA 4MQWB 4YCGC 2QJAA 1M4UA 1NYUB 3BK3A 1REWA 4LXRJ 1KATW 1PDGA 1MKGA 3EO1C 2ARPA
chains in the Genus database with same CATH topology
3SEKB 1TZHV 2ARVA 2H64A 5HI3A 1QFWA 5HHXA 1HCFA 1KLCA 4UI0A 1BNDA 4UHZA 1TGJA 4N1DA 4KXZA 1BTGA 2XV7A 5HHCA 5BQCA 3QB4A 1XWDA 1QFWB 5BQ8D 1BNDB 4AY9B 2VWEA 5HI4A 2BHKA 1HD4A 2GYZA 1WWWV 1BMPA 1B8MB 1NT3A 1MKKA 2H62A 2GNNA 1B98A 5HI5A 2KD3A 2IFGE 3IJ2A 5BQEB 3V2AA 3HH2A 4YCIC 2B0UA 1DZ7A 3KFDA 2R52A 3MJKA 5E4GA 2C7WA 2QJ9A 2R53A 3E07A 1SG1A 1JPYA 2X1XE 4GLNE 4QCIC 2XACA 4ZFFC 4UHYA 1ZKZA 3QTKA 4QAFC 1TGKA 4XPJA 5F3HI 3B4VA 3BMPA 1B8KA 4HQXA 1VPPV 1LX5A 1REUA 3JVFA 4FAOA 3BDYV 1FZVA 3EVSB 1TZIV 1XWDB 5HHDA 4KZNA 5F3BC 2VPFA 1QTYR 1AOCA 1HCNA 1KLAA 1KTZA 2QCWA 5BQ8A 3S1KV 1FLTV 2QJBA 2V5EB 1FL7A 4UI1A 4MIDA 4GLSE 1MJVA 2GYRA 1WQ9A 4ZBNA 4MQWA 1CZ8V 1WQ8A 4EDWV 3S1BV 4EFVA 2PJYA 1SGFB 5FV2V 1BETA 1ES7A 1HCNB 5BQ8B 4QHUC 4LXSJ 1FL7B 4EAXA 4BV4L 3FUBB 4HQUA 2FJHV 3MJGA 2GOOA 1RV6V 5FV1V 4HSAA 1BJ1V 4HR9A 1S4YB 4KV5A 5BQBA 4EDXV 2FJGV 1AGQA 3V6BA 2QCQA 4WPBA 5HHVA 1NYSB 1E9JA 2ASKA 4EC7A 5HK5A 4UI2B 1M4UL 4MPLA 4AY9A 5AEJA 5JZ7A 2TGIA 5BPUA 1HRPA 3RJRA 2X1WA 4X1JA 3BUKA 1B8MA 2VXSA 1WAQA 1TFGA 2QR0C 3P9WA 5BQEA 2P6AA 5HK5E 2GH0C 1LXIA 1HRPB 1WQ9B 1VPFA 4MQWB 4YCGC 2QJAA 1M4UA 1NYUB 3BK3A 1REWA 4LXRJ 1KATW 1PDGA 1MKGA 3EO1C 2ARPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SEK B;  1TZH V;  2ARV A;  2H64 A;  5HI3 A;  1QFW A;  5HHX A;  1HCF A;  1KLC A;  4UI0 A;  1BND A;  4UHZ A;  1TGJ A;  4N1D A;  4KXZ A;  1BTG A;  2XV7 A;  5HHC A;  5BQC A;  3QB4 A;  1XWD A;  1QFW B;  5BQ8 D;  1BND B;  4AY9 B;  2VWE A;  5HI4 A;  2BHK A;  1HD4 A;  2GYZ A;  1WWW V;  1BMP A;  1B8M B;  1NT3 A;  1MKK A;  2H62 A;  2GNN A;  1B98 A;  5HI5 A;  2KD3 A;  2IFG E;  3IJ2 A;  5BQE B;  3V2A A;  3HH2 A;  4YCI C;  2B0U A;  1DZ7 A;  3KFD A;  2R52 A;  3MJK A;  5E4G A;  2C7W A;  2QJ9 A;  2R53 A;  3E07 A;  1SG1 A;  1JPY A;  2X1X E;  4GLN E;  4QCI C;  2XAC A;  4ZFF C;  4UHY A;  1ZKZ A;  3QTK A;  4QAF C;  1TGK A;  4XPJ A;  5F3H I;  3B4V A;  3BMP A;  1B8K A;  4HQX A;  1VPP V;  1LX5 A;  1REU A;  3JVF A;  4FAO A;  3BDY V;  1FZV A;  3EVS B;  1TZI V;  1XWD B;  5HHD A;  4KZN A;  5F3B C;  2VPF A;  1QTY R;  1AOC A;  1HCN A;  1KLA A;  1KTZ A;  2QCW A;  5BQ8 A;  3S1K V;  1FLT V;  2QJB A;  2V5E B;  1FL7 A;  4UI1 A;  4MID A;  4GLS E;  1MJV A;  2GYR A;  1WQ9 A;  4ZBN A;  4MQW A;  1CZ8 V;  1WQ8 A;  4EDW V;  3S1B V;  4EFV A;  2PJY A;  1SGF B;  5FV2 V;  1BET A;  1ES7 A;  1HCN B;  5BQ8 B;  4QHU C;  4LXS J;  1FL7 B;  4EAX A;  4BV4 L;  3FUB B;  4HQU A;  2FJH V;  3MJG A;  2GOO A;  1RV6 V;  5FV1 V;  4HSA A;  1BJ1 V;  4HR9 A;  1S4Y B;  4KV5 A;  5BQB A;  4EDX V;  2FJG V;  1AGQ A;  3V6B A;  2QCQ A;  4WPB A;  5HHV A;  1NYS B;  1E9J A;  2ASK A;  4EC7 A;  5HK5 A;  4UI2 B;  1M4U L;  4MPL A;  4AY9 A;  5AEJ A;  5JZ7 A;  2TGI A;  5BPU A;  1HRP A;  3RJR A;  2X1W A;  4X1J A;  3BUK A;  1B8M A;  2VXS A;  1WAQ A;  1TFG A;  2QR0 C;  3P9W A;  5BQE A;  2P6A A;  5HK5 E;  2GH0 C;  1LXI A;  1HRP B;  1WQ9 B;  1VPF A;  4MQW B;  4YCG C;  2QJA A;  1M4U A;  1NYU B;  3BK3 A;  1REW A;  4LXR J;  1KAT W;  1PDG A;  1MKG A;  3EO1 C;  2ARP A; 
#chains in the Genus database with same CATH topology
 3SEK B;  1TZH V;  2ARV A;  2H64 A;  5HI3 A;  1QFW A;  5HHX A;  1HCF A;  1KLC A;  4UI0 A;  1BND A;  4UHZ A;  1TGJ A;  4N1D A;  4KXZ A;  1BTG A;  2XV7 A;  5HHC A;  5BQC A;  3QB4 A;  1XWD A;  1QFW B;  5BQ8 D;  1BND B;  4AY9 B;  2VWE A;  5HI4 A;  2BHK A;  1HD4 A;  2GYZ A;  1WWW V;  1BMP A;  1B8M B;  1NT3 A;  1MKK A;  2H62 A;  2GNN A;  1B98 A;  5HI5 A;  2KD3 A;  2IFG E;  3IJ2 A;  5BQE B;  3V2A A;  3HH2 A;  4YCI C;  2B0U A;  1DZ7 A;  3KFD A;  2R52 A;  3MJK A;  5E4G A;  2C7W A;  2QJ9 A;  2R53 A;  3E07 A;  1SG1 A;  1JPY A;  2X1X E;  4GLN E;  4QCI C;  2XAC A;  4ZFF C;  4UHY A;  1ZKZ A;  3QTK A;  4QAF C;  1TGK A;  4XPJ A;  5F3H I;  3B4V A;  3BMP A;  1B8K A;  4HQX A;  1VPP V;  1LX5 A;  1REU A;  3JVF A;  4FAO A;  3BDY V;  1FZV A;  3EVS B;  1TZI V;  1XWD B;  5HHD A;  4KZN A;  5F3B C;  2VPF A;  1QTY R;  1AOC A;  1HCN A;  1KLA A;  1KTZ A;  2QCW A;  5BQ8 A;  3S1K V;  1FLT V;  2QJB A;  2V5E B;  1FL7 A;  4UI1 A;  4MID A;  4GLS E;  1MJV A;  2GYR A;  1WQ9 A;  4ZBN A;  4MQW A;  1CZ8 V;  1WQ8 A;  4EDW V;  3S1B V;  4EFV A;  2PJY A;  1SGF B;  5FV2 V;  1BET A;  1ES7 A;  1HCN B;  5BQ8 B;  4QHU C;  4LXS J;  1FL7 B;  4EAX A;  4BV4 L;  3FUB B;  4HQU A;  2FJH V;  3MJG A;  2GOO A;  1RV6 V;  5FV1 V;  4HSA A;  1BJ1 V;  4HR9 A;  1S4Y B;  4KV5 A;  5BQB A;  4EDX V;  2FJG V;  1AGQ A;  3V6B A;  2QCQ A;  4WPB A;  5HHV A;  1NYS B;  1E9J A;  2ASK A;  4EC7 A;  5HK5 A;  4UI2 B;  1M4U L;  4MPL A;  4AY9 A;  5AEJ A;  5JZ7 A;  2TGI A;  5BPU A;  1HRP A;  3RJR A;  2X1W A;  4X1J A;  3BUK A;  1B8M A;  2VXS A;  1WAQ A;  1TFG A;  2QR0 C;  3P9W A;  5BQE A;  2P6A A;  5HK5 E;  2GH0 C;  1LXI A;  1HRP B;  1WQ9 B;  1VPF A;  4MQW B;  4YCG C;  2QJA A;  1M4U A;  1NYU B;  3BK3 A;  1REW A;  4LXR J;  1KAT W;  1PDG A;  1MKG A;  3EO1 C;  2ARP A; 
#chains in the Genus database with same CATH homology
 3SEK B;  1TZH V;  2ARV A;  2H64 A;  5HI3 A;  1QFW A;  5HHX A;  1HCF A;  1KLC A;  4UI0 A;  1BND A;  4UHZ A;  1TGJ A;  4N1D A;  4KXZ A;  1BTG A;  2XV7 A;  5HHC A;  5BQC A;  3QB4 A;  1XWD A;  1QFW B;  5BQ8 D;  1BND B;  4AY9 B;  2VWE A;  5HI4 A;  2BHK A;  1HD4 A;  2GYZ A;  1WWW V;  1BMP A;  1B8M B;  1NT3 A;  1MKK A;  2H62 A;  2GNN A;  1B98 A;  5HI5 A;  2KD3 A;  2IFG E;  3IJ2 A;  5BQE B;  3V2A A;  3HH2 A;  4YCI C;  2B0U A;  1DZ7 A;  3KFD A;  2R52 A;  3MJK A;  5E4G A;  2C7W A;  2QJ9 A;  2R53 A;  3E07 A;  1SG1 A;  1JPY A;  2X1X E;  4GLN E;  4QCI C;  2XAC A;  4ZFF C;  4UHY A;  1ZKZ A;  3QTK A;  4QAF C;  1TGK A;  4XPJ A;  5F3H I;  3B4V A;  3BMP A;  1B8K A;  4HQX A;  1VPP V;  1LX5 A;  1REU A;  3JVF A;  4FAO A;  3BDY V;  1FZV A;  3EVS B;  1TZI V;  1XWD B;  5HHD A;  4KZN A;  5F3B C;  2VPF A;  1QTY R;  1AOC A;  1HCN A;  1KLA A;  1KTZ A;  2QCW A;  5BQ8 A;  3S1K V;  1FLT V;  2QJB A;  2V5E B;  1FL7 A;  4UI1 A;  4MID A;  4GLS E;  1MJV A;  2GYR A;  1WQ9 A;  4ZBN A;  4MQW A;  1CZ8 V;  1WQ8 A;  4EDW V;  3S1B V;  4EFV A;  2PJY A;  1SGF B;  5FV2 V;  1BET A;  1ES7 A;  1HCN B;  5BQ8 B;  4QHU C;  4LXS J;  1FL7 B;  4EAX A;  4BV4 L;  3FUB B;  4HQU A;  2FJH V;  3MJG A;  2GOO A;  1RV6 V;  5FV1 V;  4HSA A;  1BJ1 V;  4HR9 A;  1S4Y B;  4KV5 A;  5BQB A;  4EDX V;  2FJG V;  1AGQ A;  3V6B A;  2QCQ A;  4WPB A;  5HHV A;  1NYS B;  1E9J A;  2ASK A;  4EC7 A;  5HK5 A;  4UI2 B;  1M4U L;  4MPL A;  4AY9 A;  5AEJ A;  5JZ7 A;  2TGI A;  5BPU A;  1HRP A;  3RJR A;  2X1W A;  4X1J A;  3BUK A;  1B8M A;  2VXS A;  1WAQ A;  1TFG A;  2QR0 C;  3P9W A;  5BQE A;  2P6A A;  5HK5 E;  2GH0 C;  1LXI A;  1HRP B;  1WQ9 B;  1VPF A;  4MQW B;  4YCG C;  2QJA A;  1M4U A;  1NYU B;  3BK3 A;  1REW A;  4LXR J;  1KAT W;  1PDG A;  1MKG A;  3EO1 C;  2ARP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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