4OPXC

Structure of human parp-1 bound to a dna double strand break in complex with (2r)-5-fluoro-2-methyl-2,3-dihydro-1-benzofuran-7-carboxamide
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
481
structure length
456
Chain Sequence
AAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/dna/transferase inhibitor
source organism Homo sapiens
molecule keywords Poly [ADP-ribose] polymerase 1
total genus 110
structure length 456
sequence length 481
chains with identical sequence F
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2014-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00644 PARP Poly(ADP-ribose) polymerase catalytic domain
C PF02877 PARP_reg Poly(ADP-ribose) polymerase, regulatory domain
C PF05406 WGR WGR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.142.10 Mainly Alpha Up-down Bundle Poly(ADP-ribose) Polymerase; domain 1 Poly(ADP-ribose) polymerase, regulatory domain 4opxC03
2.20.140.10 Mainly Beta Single Sheet q64v53_bacfr protein fold WGR domain 4opxC01
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 4opxC02
5C5PA 1UK1A 5FPGA 2X5YA 4M7BA 4OQBC 5AKUA 5AL5A 4DQYC 4J1ZA 4L7LA 4N4VA 4DVIA 4F1LA 5ADQA 2PAWA 4BUTA 4F1QA 4HMHA 5LX6A 4UI6A 4J3MA 4UI4A 4UUHA 4UVNA 2RF5A 4KRSA 4PNMA 4L2GA 1WOKA 2RCWA 4HL5A 4UVWA 4L33A 4UVXA 3P0PA 4TORA 1PAXA 2PQFA 4HKNA 4XHUA 3KCZA 4K4FA 4LI6A 5AL4A 3PAXA 4L2FA 5ECEA 4L0TA 2RA8A 4TKIA 4AVUA 3UH4A 1A26A 4R5WA 3MHJA 4UFYA 5C5QA 1UK0A 4ZZXA 4UVOA 4UVPA 4L70A 5ADTA 4L7RA 4KZLA 5ADRA 3SMJA 4L0BA 4TJYA 4HYFA 4J21A 5ADSA 3GEYA 3SMIA 4GV0A 4L09A 4ZZYA 4UI3A 4BJ9A 3BLJA 4UHGA 4PJVA 4U6AA 4N3RA 5ETYA 4BUFA 4PNLA 4TOSA 4TJUA 5AL1A 4UW1A 2RD6A 5A00A 4ZZZA 4PNNA 4MSKA 3W51A 3C49A 4HHYA 3UDDA 4L7UA 4L31A 4TK0A 4UI8A 4F0EA 4BU7A 4UFUA 5AL3A 3L3MA 4LI8A 4UVVA 3C4HA 3U9YA 3KR7A 4J3LA 4IUEA 4UNDA 4L0SA 4BU6A 4UX4A 4PNQA 4BU9A 3KJDA 4HLFA 4TJWA 4PNTA 3KR8A 3L3LA 4L0VA 4L2KA 4R6EA 4W5IA 3GJWA 4J22A 5AEHA 4L7PA 4UI5A 4BUEA 3HKVA 4BUXA 3SE2A 4N4TA 4L7NA 4PNRA 4MSGA 3GN7A 4L6SA 4OQAC 2EOCA 4HLMA 4TK5A 5AL2A 4AVWA 4BUWA 4BUVA 4LI7A 4PMLA 4BJBA 4BUYA 5LYHA 4UVYA 4OPXC 2CR9A 5EBTA 5C5RA 4L32A 4OA7A 4HKKA 4UI7A 4UVTA 2PAXA 4TKFA 4BUIA 3MHKA 4KZUA 4PY4A 4HLKA 4GV7A 3FHBA 4PJTA 4UVLA 4UVSA 3CE0A 4L6ZA 3UH2A 4BU5A 4GV2A 3GOYA 5AKWA 4W6EA 5LXPA 4L34A 4K4EA 4BFPA 4BU8A 4BUDA 4BUAA 4L10A 4UVZA 4I9IA 4W5SA 4X52A 4PAXA 4PNSA 4TKGA 3U9HA 4HKIA 4UVUA 4UXBA 4KZQA 4BUUA 5DCZA 4HHZA 4BS4A 4RV6A 4HLGA 3P0NA 3P0QA 4HLHA 4GV4A 4TVJA 3UA9A 5FPFA 1GS0A 4BUSA 1EFYA 4L0IA 4MT9A 4BU3A 4L7OA 4BJCA
chains in the Genus database with same CATH superfamily
5C5PA 2X5YA 4J1ZA 4L7LA 5FH2A 5ADQA 4BUTA 5LX6A 5FH1A 4UI4A 4PNMA 4RCGA 3DTBA 1PAXA 2RK7A 3MHJA 4UFYA 5C5QA 4GMMA 4L70A 5ADTA 2RKAA 4HYFA 3SMIA 3MOEA 4UHGA 1XKVA 5ETYA 5AL1A 4IJSA 3UDDA 4LI8A 3KR7A 4L0SA 4IUEA 3KJDA 4PNTA 1YLHA 1YTMA 4J22A 2QEWA 3HKVA 3SE2A 3GN7A 4L6SA 5AL2A 4LI7A 2GMVA 4OPXC 2CR9A 4BUIA 3MOHA 1II2A 1KHEA 4HLKA 3FHBA 2ZCIA 2OLQA 1OS1A 5AKWA 4L34A 4K4EA 4BFPA 2FAFA 2HZSA 4PNSA 4TKGA 4UXBA 4HHZA 3P0QA 3UA9A 5FPFA 1GS0A 4L0IA 4BJCA 4OQBC 2RK8A 4N4VA 2PAWA 4UUHA 1WOKA 2RCWA 4L33A 4GNOA 4UVXA 2PQFA 4HKNA 3PAXA 1M51A 4L0TA 4BHHB 1K3CA 4ZZXA 4J1JA 4UVPA 4L7RA 5ADRA 4L0BA 4L09A 4UI3A 3BLJA 4PJVA 5FH0A 4BUFA 4IDUA 5A00A 4HHYA 4UI8A 4F0EA 4UFUA 4UVVA 5FH4A 3C4HA 4BU6A 1AQ2A 3KR8A 4L0VA 5I67A 4L7PA 5FH5A 4WOUA 4OQAC 4R43A 5LYHA 4L32A 4UI7A 4UVTA 2PAXA 4GMZA 4GV7A 4WPVA 4PJTA 4UVLA 4UVSA 3CE0A 3UH2A 3GOYA 4W6EA 4BU8A 1J3BA 4GNLA 4L10A 4UVZA 4W5SA 4X52A 4KZQA 4IDXA 1KHBA 4RV6A 4HLGA 4HLHA 4TVJA 2QF2A 1KHFA 1A26A 5AKUA 5AL5A 4DQYC 1AYLA 4YW9A 1YVYA 4F1QA 4J3MA 4UVNA 4KRSA 4L2GA 4UVWA 4TORA 2RKEA 4K4FA 4LI6A 4XHUA 4TKIA 2RA8A 4BGPA 4YW8A 4R5WA 1UK0A 4UVOA 4YWBA 4TJYA 4J21A 4GV0A 4ZZYA 4BJ9A 4PNLA 4TJUA 3ZL9A 4UW1A 2RD6A 4MSKA 3C49A 3ZLAA 4WPUA 2HZMA 4WL8A 4BU7A 3L3MA 4GMWA 4YWDA 3U9YA 4J3LA 4GNQA 4UX4A 3L3LA 3DT7A 4BUEA 4BUXA 4N4TA 4L7NA 4PNRA 4GNPA 4HLMA 4TK5A 2EOCA 4BUWA 2RKDA 4PMLA 1KHGA 4BJBA 4IDUB 4OX2A 4BUYA 5C5RA 4OA7A 4KZUA 4GMUA 4JNGA 1NHXA 4WIEA 4BU5A 4GV2A 2OLRA 1OENA 4I9IA 3U9HA 4HKIA 4UVUA 3DT4A 2FAHA 4BUSA 1EFYA 4L7OA 3MOFA 4WPTA 1UK1A 5FPGA 4M7BA 4DVIA 4F1LA 2PY7X 1K3DA 4HMHA 4UI6A 2QZYA 2RF5A 4HL5A 2PXZX 2PC9A 3P0PA 3KCZA 5ECEA 5AL4A 4L2FA 4AVUA 3UH4A 2QEYA 4KZLA 3SMJA 4J1GA 5ADSA 3GEYA 4U6AA 4N3RA 4TOSA 2QF1A 4ZZZA 4PNNA 3W51A 4L7UA 4L31A 4TK0A 5AL3A 5FH3A 4UNDA 4BU9A 4PNQA 4TJWA 4HLFA 4W5IA 4L2KA 1YGGA 4R6EA 3GJWA 5AEHA 4UI5A 4MSGA 4AVWA 4BUVA 4GNMA 3DT2A 4UVYA 5EBTA 4HKKA 4TKFA 3MHKA 4PY4A 4L6ZA 4WIUA 5LXPA 4BUDA 4BUAA 4PAXA 4BUUA 5DCZA 4BS4A 3P0NA 4GV4A 4MT9A 4BU3A
chains in the Genus database with same CATH topology
5C5PA 2X5YA 4J1ZA 4L7LA 5FH2A 5ADQA 4BUTA 5LX6A 5FH1A 4UI4A 4PNMA 4RCGA 3DTBA 1PAXA 2RK7A 3MHJA 4UFYA 5C5QA 4GMMA 4L70A 5ADTA 2RKAA 4HYFA 3SMIA 3MOEA 4UHGA 1XKVA 5ETYA 5AL1A 3UDDA 4LI8A 3KR7A 4L0SA 4IUEA 3KJDA 4PNTA 1YLHA 1YTMA 4J22A 2QEWA 3HKVA 3SE2A 3GN7A 4L6SA 5AL2A 4LI7A 2GMVA 4OPXC 2CR9A 4BUIA 3MOHA 1II2A 1KHEA 4HLKA 3FHBA 2ZCIA 2OLQA 1OS1A 5AKWA 4L34A 4K4EA 4BFPA 2FAFA 4PNSA 4TKGA 4UXBA 4HHZA 3P0QA 3UA9A 5FPFA 1GS0A 4L0IA 4BJCA 4OQBC 2RK8A 4N4VA 2PAWA 4UUHA 1WOKA 2RCWA 4L33A 4GNOA 4UVXA 2PQFA 4HKNA 3PAXA 1M51A 4L0TA 1K3CA 4ZZXA 4UVPA 4L7RA 5ADRA 4L0BA 4L09A 4UI3A 3BLJA 4PJVA 5FH0A 4BUFA 5A00A 4HHYA 4UI8A 4F0EA 4UFUA 4UVVA 5FH4A 3C4HA 4BU6A 1AQ2A 3KR8A 4L0VA 5I67A 4L7PA 5FH5A 4WOUA 4OQAC 4R43A 5LYHA 4L32A 4UI7A 4UVTA 2PAXA 4GMZA 4GV7A 4WPVA 4PJTA 4UVLA 4UVSA 3CE0A 3UH2A 3GOYA 4W6EA 4BU8A 1J3BA 4GNLA 4L10A 4UVZA 4W5SA 4X52A 4KZQA 1KHBA 4RV6A 4HLGA 4HLHA 4TVJA 2QF2A 1KHFA 1A26A 5AKUA 5AL5A 4DQYC 1AYLA 4YW9A 1YVYA 4F1QA 4J3MA 4UVNA 4KRSA 4L2GA 4UVWA 4TORA 2RKEA 4K4FA 4LI6A 4XHUA 4TKIA 2RA8A 4YW8A 4R5WA 1UK0A 4UVOA 4YWBA 4TJYA 4J21A 4GV0A 4ZZYA 4BJ9A 4PNLA 4TJUA 4UW1A 2RD6A 4MSKA 3C49A 4WPUA 4BU7A 4WL8A 3L3MA 4GMWA 4YWDA 3U9YA 4J3LA 4GNQA 4UX4A 3L3LA 3DT7A 4BUEA 4BUXA 4N4TA 4L7NA 4PNRA 4GNPA 4HLMA 4TK5A 2EOCA 4BUWA 2RKDA 4PMLA 1KHGA 4BJBA 4OX2A 4BUYA 5C5RA 4OA7A 4KZUA 4GMUA 1NHXA 4WIEA 4BU5A 4GV2A 2OLRA 1OENA 4I9IA 3U9HA 4HKIA 4UVUA 3DT4A 2FAHA 4BUSA 1EFYA 4L7OA 3MOFA 4WPTA 1UK1A 5FPGA 4M7BA 4DVIA 4F1LA 2PY7X 1K3DA 4HMHA 4UI6A 2QZYA 2RF5A 4HL5A 2PXZX 2PC9A 3P0PA 3KCZA 5ECEA 5AL4A 4L2FA 4AVUA 3UH4A 2QEYA 4KZLA 3SMJA 5ADSA 3GEYA 4U6AA 4N3RA 4TOSA 2QF1A 4ZZZA 4PNNA 3W51A 4L7UA 4L31A 4TK0A 5AL3A 5FH3A 4UNDA 4BU9A 4PNQA 4TJWA 4HLFA 4W5IA 4L2KA 1YGGA 4R6EA 3GJWA 5AEHA 4UI5A 4MSGA 4AVWA 4BUVA 4GNMA 3DT2A 4UVYA 5EBTA 4HKKA 4TKFA 3MHKA 4PY4A 4L6ZA 4WIUA 5LXPA 4BUDA 4BUAA 4PAXA 4BUUA 5DCZA 4BS4A 3P0NA 4GV4A 4MT9A 4BU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C5P A;  1UK1 A;  5FPG A;  2X5Y A;  4M7B A;  4OQB C;  5AKU A;  5AL5 A;  4DQY C;  4J1Z A;  4L7L A;  4N4V A;  4DVI A;  4F1L A;  5ADQ A;  2PAW A;  4BUT A;  4F1Q A;  4HMH A;  5LX6 A;  4UI6 A;  4J3M A;  4UI4 A;  4UUH A;  4UVN A;  2RF5 A;  4KRS A;  4PNM A;  4L2G A;  1WOK A;  2RCW A;  4HL5 A;  4UVW A;  4L33 A;  4UVX A;  3P0P A;  4TOR A;  1PAX A;  2PQF A;  4HKN A;  4XHU A;  3KCZ A;  4K4F A;  4LI6 A;  5AL4 A;  3PAX A;  4L2F A;  5ECE A;  4L0T A;  2RA8 A;  4TKI A;  4AVU A;  3UH4 A;  1A26 A;  4R5W A;  3MHJ A;  4UFY A;  5C5Q A;  1UK0 A;  4ZZX A;  4UVO A;  4UVP A;  4L70 A;  5ADT A;  4L7R A;  4KZL A;  5ADR A;  3SMJ A;  4L0B A;  4TJY A;  4HYF A;  4J21 A;  5ADS A;  3GEY A;  3SMI A;  4GV0 A;  4L09 A;  4ZZY A;  4UI3 A;  4BJ9 A;  3BLJ A;  4UHG A;  4PJV A;  4U6A A;  4N3R A;  5ETY A;  4BUF A;  4PNL A;  4TOS A;  4TJU A;  5AL1 A;  4UW1 A;  2RD6 A;  5A00 A;  4ZZZ A;  4PNN A;  4MSK A;  3W51 A;  3C49 A;  4HHY A;  3UDD A;  4L7U A;  4L31 A;  4TK0 A;  4UI8 A;  4F0E A;  4BU7 A;  4UFU A;  5AL3 A;  3L3M A;  4LI8 A;  4UVV A;  3C4H A;  3U9Y A;  3KR7 A;  4J3L A;  4IUE A;  4UND A;  4L0S A;  4BU6 A;  4UX4 A;  4PNQ A;  4BU9 A;  3KJD A;  4HLF A;  4TJW A;  4PNT A;  3KR8 A;  3L3L A;  4L0V A;  4L2K A;  4R6E A;  4W5I A;  3GJW A;  4J22 A;  5AEH A;  4L7P A;  4UI5 A;  4BUE A;  3HKV A;  4BUX A;  3SE2 A;  4N4T A;  4L7N A;  4PNR A;  4MSG A;  3GN7 A;  4L6S A;  4OQA C;  2EOC A;  4HLM A;  4TK5 A;  5AL2 A;  4AVW A;  4BUW A;  4BUV A;  4LI7 A;  4PML A;  4BJB A;  4BUY A;  5LYH A;  4UVY A;  4OPX C;  2CR9 A;  5EBT A;  5C5R A;  4L32 A;  4OA7 A;  4HKK A;  4UI7 A;  4UVT A;  2PAX A;  4TKF A;  4BUI A;  3MHK A;  4KZU A;  4PY4 A;  4HLK A;  4GV7 A;  3FHB A;  4PJT A;  4UVL A;  4UVS A;  3CE0 A;  4L6Z A;  3UH2 A;  4BU5 A;  4GV2 A;  3GOY A;  5AKW A;  4W6E A;  5LXP A;  4L34 A;  4K4E A;  4BFP A;  4BU8 A;  4BUD A;  4BUA A;  4L10 A;  4UVZ A;  4I9I A;  4W5S A;  4X52 A;  4PAX A;  4PNS A;  4TKG A;  3U9H A;  4HKI A;  4UVU A;  4UXB A;  4KZQ A;  4BUU A;  5DCZ A;  4HHZ A;  4BS4 A;  4RV6 A;  4HLG A;  3P0N A;  3P0Q A;  4HLH A;  4GV4 A;  4TVJ A;  3UA9 A;  5FPF A;  1GS0 A;  4BUS A;  1EFY A;  4L0I A;  4MT9 A;  4BU3 A;  4L7O A;  4BJC A; 
#chains in the Genus database with same CATH topology
 5C5P A;  2X5Y A;  4J1Z A;  4L7L A;  5FH2 A;  5ADQ A;  4BUT A;  5LX6 A;  5FH1 A;  4UI4 A;  4PNM A;  4RCG A;  3DTB A;  1PAX A;  2RK7 A;  3MHJ A;  4UFY A;  5C5Q A;  4GMM A;  4L70 A;  5ADT A;  2RKA A;  4HYF A;  3SMI A;  3MOE A;  4UHG A;  1XKV A;  5ETY A;  5AL1 A;  4IJS A;  3UDD A;  4LI8 A;  3KR7 A;  4L0S A;  4IUE A;  3KJD A;  4PNT A;  1YLH A;  1YTM A;  4J22 A;  2QEW A;  3HKV A;  3SE2 A;  3GN7 A;  4L6S A;  5AL2 A;  4LI7 A;  2GMV A;  4OPX C;  2CR9 A;  4BUI A;  3MOH A;  1II2 A;  1KHE A;  4HLK A;  3FHB A;  2ZCI A;  2OLQ A;  1OS1 A;  5AKW A;  4L34 A;  4K4E A;  4BFP A;  2FAF A;  2HZS A;  4PNS A;  4TKG A;  4UXB A;  4HHZ A;  3P0Q A;  3UA9 A;  5FPF A;  1GS0 A;  4L0I A;  4BJC A;  4OQB C;  2RK8 A;  4N4V A;  2PAW A;  4UUH A;  1WOK A;  2RCW A;  4L33 A;  4GNO A;  4UVX A;  2PQF A;  4HKN A;  3PAX A;  1M51 A;  4L0T A;  4BHH B;  1K3C A;  4ZZX A;  4J1J A;  4UVP A;  4L7R A;  5ADR A;  4L0B A;  4L09 A;  4UI3 A;  3BLJ A;  4PJV A;  5FH0 A;  4BUF A;  4IDU A;  5A00 A;  4HHY A;  4UI8 A;  4F0E A;  4UFU A;  4UVV A;  5FH4 A;  3C4H A;  4BU6 A;  1AQ2 A;  3KR8 A;  4L0V A;  5I67 A;  4L7P A;  5FH5 A;  4WOU A;  4OQA C;  4R43 A;  5LYH A;  4L32 A;  4UI7 A;  4UVT A;  2PAX A;  4GMZ A;  4GV7 A;  4WPV A;  4PJT A;  4UVL A;  4UVS A;  3CE0 A;  3UH2 A;  3GOY A;  4W6E A;  4BU8 A;  1J3B A;  4GNL A;  4L10 A;  4UVZ A;  4W5S A;  4X52 A;  4KZQ A;  4IDX A;  1KHB A;  4RV6 A;  4HLG A;  4HLH A;  4TVJ A;  2QF2 A;  1KHF A;  1A26 A;  5AKU A;  5AL5 A;  4DQY C;  1AYL A;  4YW9 A;  1YVY A;  4F1Q A;  4J3M A;  4UVN A;  4KRS A;  4L2G A;  4UVW A;  4TOR A;  2RKE A;  4K4F A;  4LI6 A;  4XHU A;  4TKI A;  2RA8 A;  4BGP A;  4YW8 A;  4R5W A;  1UK0 A;  4UVO A;  4YWB A;  4TJY A;  4J21 A;  4GV0 A;  4ZZY A;  4BJ9 A;  4PNL A;  4TJU A;  3ZL9 A;  4UW1 A;  2RD6 A;  4MSK A;  3C49 A;  3ZLA A;  4WPU A;  2HZM A;  4WL8 A;  4BU7 A;  3L3M A;  4GMW A;  4YWD A;  3U9Y A;  4J3L A;  4GNQ A;  4UX4 A;  3L3L A;  3DT7 A;  4BUE A;  4BUX A;  4N4T A;  4L7N A;  4PNR A;  4GNP A;  4HLM A;  4TK5 A;  2EOC A;  4BUW A;  2RKD A;  4PML A;  1KHG A;  4BJB A;  4IDU B;  4OX2 A;  4BUY A;  5C5R A;  4OA7 A;  4KZU A;  4GMU A;  4JNG A;  1NHX A;  4WIE A;  4BU5 A;  4GV2 A;  2OLR A;  1OEN A;  4I9I A;  3U9H A;  4HKI A;  4UVU A;  3DT4 A;  2FAH A;  4BUS A;  1EFY A;  4L7O A;  3MOF A;  4WPT A;  1UK1 A;  5FPG A;  4M7B A;  4DVI A;  4F1L A;  2PY7 X;  1K3D A;  4HMH A;  4UI6 A;  2QZY A;  2RF5 A;  4HL5 A;  2PXZ X;  2PC9 A;  3P0P A;  3KCZ A;  5ECE A;  5AL4 A;  4L2F A;  4AVU A;  3UH4 A;  2QEY A;  4KZL A;  3SMJ A;  4J1G A;  5ADS A;  3GEY A;  4U6A A;  4N3R A;  4TOS A;  2QF1 A;  4ZZZ A;  4PNN A;  3W51 A;  4L7U A;  4L31 A;  4TK0 A;  5AL3 A;  5FH3 A;  4UND A;  4BU9 A;  4PNQ A;  4TJW A;  4HLF A;  4W5I A;  4L2K A;  1YGG A;  4R6E A;  3GJW A;  5AEH A;  4UI5 A;  4MSG A;  4AVW A;  4BUV A;  4GNM A;  3DT2 A;  4UVY A;  5EBT A;  4HKK A;  4TKF A;  3MHK A;  4PY4 A;  4L6Z A;  4WIU A;  5LXP A;  4BUD A;  4BUA A;  4PAX A;  4BUU A;  5DCZ A;  4BS4 A;  3P0N A;  4GV4 A;  4MT9 A;  4BU3 A; 
#chains in the Genus database with same CATH homology
 5C5P A;  2X5Y A;  4J1Z A;  4L7L A;  5FH2 A;  5ADQ A;  4BUT A;  5LX6 A;  5FH1 A;  4UI4 A;  4PNM A;  4RCG A;  3DTB A;  1PAX A;  2RK7 A;  3MHJ A;  4UFY A;  5C5Q A;  4GMM A;  4L70 A;  5ADT A;  2RKA A;  4HYF A;  3SMI A;  3MOE A;  4UHG A;  1XKV A;  5ETY A;  5AL1 A;  3UDD A;  4LI8 A;  3KR7 A;  4L0S A;  4IUE A;  3KJD A;  4PNT A;  1YLH A;  1YTM A;  4J22 A;  2QEW A;  3HKV A;  3SE2 A;  3GN7 A;  4L6S A;  5AL2 A;  4LI7 A;  2GMV A;  4OPX C;  2CR9 A;  4BUI A;  3MOH A;  1II2 A;  1KHE A;  4HLK A;  3FHB A;  2ZCI A;  2OLQ A;  1OS1 A;  5AKW A;  4L34 A;  4K4E A;  4BFP A;  2FAF A;  4PNS A;  4TKG A;  4UXB A;  4HHZ A;  3P0Q A;  3UA9 A;  5FPF A;  1GS0 A;  4L0I A;  4BJC A;  4OQB C;  2RK8 A;  4N4V A;  2PAW A;  4UUH A;  1WOK A;  2RCW A;  4L33 A;  4GNO A;  4UVX A;  2PQF A;  4HKN A;  3PAX A;  1M51 A;  4L0T A;  1K3C A;  4ZZX A;  4UVP A;  4L7R A;  5ADR A;  4L0B A;  4L09 A;  4UI3 A;  3BLJ A;  4PJV A;  5FH0 A;  4BUF A;  5A00 A;  4HHY A;  4UI8 A;  4F0E A;  4UFU A;  4UVV A;  5FH4 A;  3C4H A;  4BU6 A;  1AQ2 A;  3KR8 A;  4L0V A;  5I67 A;  4L7P A;  5FH5 A;  4WOU A;  4OQA C;  4R43 A;  5LYH A;  4L32 A;  4UI7 A;  4UVT A;  2PAX A;  4GMZ A;  4GV7 A;  4WPV A;  4PJT A;  4UVL A;  4UVS A;  3CE0 A;  3UH2 A;  3GOY A;  4W6E A;  4BU8 A;  1J3B A;  4GNL A;  4L10 A;  4UVZ A;  4W5S A;  4X52 A;  4KZQ A;  1KHB A;  4RV6 A;  4HLG A;  4HLH A;  4TVJ A;  2QF2 A;  1KHF A;  1A26 A;  5AKU A;  5AL5 A;  4DQY C;  1AYL A;  4YW9 A;  1YVY A;  4F1Q A;  4J3M A;  4UVN A;  4KRS A;  4L2G A;  4UVW A;  4TOR A;  2RKE A;  4K4F A;  4LI6 A;  4XHU A;  4TKI A;  2RA8 A;  4YW8 A;  4R5W A;  1UK0 A;  4UVO A;  4YWB A;  4TJY A;  4J21 A;  4GV0 A;  4ZZY A;  4BJ9 A;  4PNL A;  4TJU A;  4UW1 A;  2RD6 A;  4MSK A;  3C49 A;  4WPU A;  4BU7 A;  4WL8 A;  3L3M A;  4GMW A;  4YWD A;  3U9Y A;  4J3L A;  4GNQ A;  4UX4 A;  3L3L A;  3DT7 A;  4BUE A;  4BUX A;  4N4T A;  4L7N A;  4PNR A;  4GNP A;  4HLM A;  4TK5 A;  2EOC A;  4BUW A;  2RKD A;  4PML A;  1KHG A;  4BJB A;  4OX2 A;  4BUY A;  5C5R A;  4OA7 A;  4KZU A;  4GMU A;  1NHX A;  4WIE A;  4BU5 A;  4GV2 A;  2OLR A;  1OEN A;  4I9I A;  3U9H A;  4HKI A;  4UVU A;  3DT4 A;  2FAH A;  4BUS A;  1EFY A;  4L7O A;  3MOF A;  4WPT A;  1UK1 A;  5FPG A;  4M7B A;  4DVI A;  4F1L A;  2PY7 X;  1K3D A;  4HMH A;  4UI6 A;  2QZY A;  2RF5 A;  4HL5 A;  2PXZ X;  2PC9 A;  3P0P A;  3KCZ A;  5ECE A;  5AL4 A;  4L2F A;  4AVU A;  3UH4 A;  2QEY A;  4KZL A;  3SMJ A;  5ADS A;  3GEY A;  4U6A A;  4N3R A;  4TOS A;  2QF1 A;  4ZZZ A;  4PNN A;  3W51 A;  4L7U A;  4L31 A;  4TK0 A;  5AL3 A;  5FH3 A;  4UND A;  4BU9 A;  4PNQ A;  4TJW A;  4HLF A;  4W5I A;  4L2K A;  1YGG A;  4R6E A;  3GJW A;  5AEH A;  4UI5 A;  4MSG A;  4AVW A;  4BUV A;  4GNM A;  3DT2 A;  4UVY A;  5EBT A;  4HKK A;  4TKF A;  3MHK A;  4PY4 A;  4L6Z A;  4WIU A;  5LXP A;  4BUD A;  4BUA A;  4PAX A;  4BUU A;  5DCZ A;  4BS4 A;  3P0N A;  4GV4 A;  4MT9 A;  4BU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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