4OQAC

Structure of human parp-1 bound to a dna double strand break in complex with (2z)-2-(2,4-dihydroxybenzylidene)-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
481
structure length
456
Chain Sequence
AAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase/dna/transferase inhibitor
molecule keywords Poly [ADP-ribose] polymerase 1
publication title Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors.
pubmed doi rcsb
source organism Homo sapiens
total genus 108
structure length 456
sequence length 481
chains with identical sequence F
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2014-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00644 PARP Poly(ADP-ribose) polymerase catalytic domain
C PF02877 PARP_reg Poly(ADP-ribose) polymerase, regulatory domain
C PF05406 WGR WGR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.142.10 Mainly Alpha Up-down Bundle Poly(ADP-ribose) Polymerase; domain 1 Poly(ADP-ribose) polymerase, regulatory domain 4oqaC03
2.20.140.10 Mainly Beta Single Sheet q64v53_bacfr protein fold WGR domain 4oqaC01
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 4oqaC02
4BUUA 4BUXA 4BUVA 4W6EA 1GS0A 4BUEA 5ADQA 3UH4A 4L70A 4UVXA 4BS4A 4UFUA 4HL5A 2X5YA 5C5QA 4L6ZA 4K4EA 4TJUA 3P0QA 3KR7A 4HLKA 4F1LA 4GV4A 3UA9A 4BUWA 3KR8A 4BU7A 4KZQA 5LX6A 5EBTA 4F0EA 4GV0A 4J21A 4LI6A 4TORA 4UVZA 4N4VA 4UUHA 4MSKA 4TK5A 5C5RA 4BUIA 4PNLA 3CE0A 2RD6A 3KCZA 4HMHA 4UI4A 2PAXA 4UI7A 4W5IA 2CR9A 3UH2A 5ECEA 4TKGA 4OA7A 4UI8A 4UI3A 4UVOA 4HHZA 3L3LA 4L7PA 5AKUA 4BUDA 5FPFA 4L7LA 4L0IA 4HLMA 5AL1A 4UVNA 1EFYA 4HHYA 4X52A 3BLJA 3PAXA 4L33A 4LI8A 4KRSA 4BUYA 4GV2A 4UI6A 3C49A 4UFYA 4DQYC 2PQFA 4PNSA 3SMJA 3U9YA 4UVTA 1UK0A 5AL4A 4PAXA 5LXPA 4UVLA 5ETYA 5A00A 4HKNA 4ZZZA 4J3LA 4L2FA 5ADSA 3GN7A 4UHGA 3MHJA 4N4TA 4OPXC 4IUEA 4L0BA 3FHBA 4BU6A 4BU5A 4HLGA 4TKIA 4PNQA 3HKVA 4KZLA 4L0TA 4TJYA 1PAXA 4J1ZA 4UXBA 3SMIA 4TJWA 4AVWA 4HKKA 4L31A 4L7NA 4UVUA 4AVUA 4BU9A 4PJVA 4I9IA 4OQAC 2RA8A 4MSGA 4GV7A 5DCZA 5C5PA 4L7RA 4BFPA 4OQBC 4J22A 4BU3A 3P0PA 5AKWA 4BUAA 2PAWA 4W5SA 4L7OA 1UK1A 4BUSA 5ADTA 1WOKA 3C4HA 4M7BA 4TVJA 4BUFA 2EOCA 4PNRA 3GJWA 3L3MA 4R5WA 3W51A 4L0SA 4ZZXA 4F1QA 4BUTA 2RCWA 4PJTA 4PMLA 4L7UA 4BU8A 4L34A 4UI5A 4UNDA 4PY4A 4KZUA 3KJDA 4UW1A 5ADRA 4L0VA 3P0NA 3U9HA 4UVVA 4UX4A 3SE2A 4L2KA 4MT9A 4HKIA 4TKFA 4L32A 4U6AA 4UVPA 5AEHA 1A26A 4PNTA 4TK0A 4J3MA 4L2GA 4PNMA 4HLHA 3GEYA 3MHKA 4HYFA 4N3RA 4PNNA 4TOSA 4L10A 5AL2A 4UVYA 5AL5A 4BJ9A 4UVSA 4BJCA 4DVIA 2RF5A 5AL3A 4L09A 4UVWA 3UDDA 5LYHA 4HLFA 3GOYA 4LI7A 4BJBA 4ZZYA 4XHUA 4K4FA 5FPGA 4RV6A 4L6SA 4R6EA
chains in the Genus database with same CATH superfamily
4BUUA 4BUVA 4BS4A 4HL5A 2X5YA 5C5QA 4F1LA 4KZQA 5LX6A 4J21A 4LI6A 2RD6A 1OENA 4W5IA 4UI7A 2PAXA 1OS1A 4YW9A 5AKUA 5AL1A 3BLJA 4L33A 2PC9A 2PQFA 5FH4A 4UVTA 2FAFA 4UVLA 4HKNA 4J3LA 4L2FA 5ADSA 4BU6A 4BU5A 4TKIA 4TJYA 3SMIA 4HKKA 4AVUA 4BU9A 4I9IA 4MSGA 5AKWA 4BUAA 4W5SA 2RKAA 3DTBA 4BUSA 4YWDA 1WOKA 4PNRA 3GJWA 1K3CA 4F1QA 4UI5A 4UNDA 4PY4A 3DT4A 3U9HA 4UVVA 4UX4A 2QZYA 4PNMA 3MHKA 2RKEA 4YWBA 4UVYA 5AL5A 5LYHA 1YTMA 4JNGA 4GMZA 4BJBA 4XHUA 4J1JA 5FPGA 4L0SA 4RV6A 5FPFA 4BUXA 4BUEA 3UH4A 4UVXA 2QEWA 4UFUA 4OX2A 3KR8A 1YLHA 3ZLAA 2ZCIA 4GV0A 5C5RA 4UUHA 4J1GA 4BUIA 1KHFA 2CR9A 3UH2A 4UI8A 4HHZA 4BUDA 4L7LA 4UVNA 4X52A 4HHYA 2QF1A 1XKVA 4LI8A 4WPUA 4GV2A 4UI6A 3C49A 4UFYA 2HZMA 3SMJA 2OLQA 1J3BA 1UK0A 4PAXA 5A00A 2RK7A 4L0BA 3FHBA 4KZLA 4UXBA 4AVWA 4L7NA 4UVUA 4PJVA 4GNOA 5DCZA 5FH5A 4OQBC 4J22A 3P0PA 1UK1A 4RCGA 2QEYA 4BUFA 2EOCA 2HZSA 4BUTA 2RCWA 4PJTA 4PMLA 4L7UA 4L34A 4KZUA 5ADRA 4L0VA 4WIUA 3SE2A 4L2KA 4U6AA 4UVPA 4PNNA 4L10A 4BJCA 4UVSA 2RF5A 4L09A 4UVWA 4HLFA 4K4FA 4R6EA 4R43A 4W6EA 1GS0A 5ADQA 2RKDA 3KR7A 4GV4A 4BU7A 1M51A 5EBTA 4F0EA 1KHGA 4TORA 4UVZA 4N4VA 4PNLA 4UI4A 4OA7A 4UI3A 3MOEA 4KRSA 4BUYA 3MOHA 4DQYC 3U9YA 2RK8A 4IDUA 3DT2A 3GN7A 4UHGA 4BHHB 4N4TA 4OPXC 5I67A 4YW8A 4HLGA 2QF2A 1K3DA 3HKVA 4PNQA 4L0TA 4L31A 2FAHA 2RA8A 4GMMA 4GV7A 2PY7X 4BFPA 4BU3A 2PAWA 4L7OA 5ADTA 3C4HA 4GNMA 3L3MA 4R5WA 1YVYA 4WIEA 4BU8A 4UW1A 3ZL9A 4MT9A 4TKFA 4L32A 5AEHA 1A26A 4TK0A 4J3MA 4L2GA 3GEYA 4HYFA 4TOSA 5AL2A 1NHXA 4BJ9A 3UDDA 3GOYA 4WPTA 4ZZYA 5AL4A 4L6SA 5FH3A 4IDXA 4L70A 2OLRA 1AYLA 4L6ZA 4K4EA 4TJUA 3P0QA 4HLKA 3UA9A 4BUWA 4GNLA 4GNQA 4MSKA 4TK5A 4IDUB 3CE0A 3KCZA 4HMHA 5ECEA 4TKGA 4UVOA 4BGPA 3L3LA 4L7PA 1KHEA 4L0IA 4HLMA 1EFYA 3PAXA 4WOUA 4PNSA 5LXPA 5ETYA 4ZZZA 3MOFA 3MHJA 4IUEA 1PAXA 4J1ZA 2GMVA 4TJWA 4IJSA 4OQAC 5FH1A 5C5PA 4L7RA 1KHBA 4GNPA 4GMWA 4GMUA 4M7BA 4TVJA 4WPVA 3W51A 4ZZXA 2PXZX 5FH0A 3KJDA 3P0NA 4WL8A 4HKIA 4PNTA 4HLHA 4N3RA 5FH2A 1II2A 4DVIA 1YGGA 1AQ2A 5AL3A 4LI7A 3DT7A
chains in the Genus database with same CATH topology
4BUUA 4BUVA 4BS4A 4HL5A 2X5YA 5C5QA 4F1LA 4KZQA 5LX6A 4J21A 4LI6A 2RD6A 1OENA 4W5IA 4UI7A 2PAXA 1OS1A 4YW9A 5AKUA 5AL1A 3BLJA 4L33A 2PC9A 2PQFA 5FH4A 4UVTA 2FAFA 4UVLA 4HKNA 4J3LA 4L2FA 5ADSA 4BU6A 4BU5A 4TKIA 4TJYA 3SMIA 4HKKA 4AVUA 4BU9A 4I9IA 4MSGA 5AKWA 4BUAA 4W5SA 2RKAA 3DTBA 4BUSA 4YWDA 1WOKA 4PNRA 3GJWA 1K3CA 4F1QA 4UI5A 4UNDA 4PY4A 3DT4A 3U9HA 4UVVA 4UX4A 2QZYA 4PNMA 3MHKA 2RKEA 4YWBA 4UVYA 5AL5A 5LYHA 1YTMA 4GMZA 4BJBA 4XHUA 5FPGA 4L0SA 4RV6A 5FPFA 4BUXA 4BUEA 3UH4A 4UVXA 2QEWA 4UFUA 4OX2A 3KR8A 1YLHA 2ZCIA 4GV0A 5C5RA 4UUHA 4BUIA 1KHFA 2CR9A 3UH2A 4UI8A 4HHZA 4BUDA 4L7LA 4UVNA 4X52A 4HHYA 2QF1A 1XKVA 4LI8A 4WPUA 4GV2A 4UI6A 3C49A 4UFYA 3SMJA 2OLQA 1J3BA 1UK0A 4PAXA 5A00A 2RK7A 4L0BA 3FHBA 4KZLA 4UXBA 4AVWA 4L7NA 4UVUA 4PJVA 4GNOA 5DCZA 5FH5A 4OQBC 4J22A 3P0PA 1UK1A 4RCGA 2QEYA 4BUFA 2EOCA 4BUTA 2RCWA 4PJTA 4PMLA 4L7UA 4L34A 4KZUA 5ADRA 4L0VA 4WIUA 3SE2A 4L2KA 4U6AA 4UVPA 4PNNA 4L10A 4BJCA 4UVSA 2RF5A 4L09A 4UVWA 4HLFA 4K4FA 4R6EA 4R43A 4W6EA 1GS0A 5ADQA 2RKDA 3KR7A 4GV4A 4BU7A 1M51A 5EBTA 4F0EA 1KHGA 4TORA 4UVZA 4N4VA 4PNLA 4UI4A 4OA7A 4UI3A 3MOEA 4KRSA 4BUYA 3MOHA 4DQYC 3U9YA 2RK8A 3DT2A 3GN7A 4UHGA 4N4TA 4OPXC 5I67A 4YW8A 4HLGA 2QF2A 1K3DA 3HKVA 4PNQA 4L0TA 4L31A 2FAHA 2RA8A 4GMMA 4GV7A 2PY7X 4BFPA 4BU3A 2PAWA 4L7OA 5ADTA 3C4HA 4GNMA 3L3MA 4R5WA 1YVYA 4WIEA 4BU8A 4UW1A 4MT9A 4TKFA 4L32A 5AEHA 1A26A 4TK0A 4J3MA 4L2GA 3GEYA 4HYFA 4TOSA 5AL2A 1NHXA 4BJ9A 3UDDA 3GOYA 4WPTA 4ZZYA 5AL4A 4L6SA 5FH3A 4L70A 2OLRA 1AYLA 4L6ZA 4K4EA 4TJUA 3P0QA 4HLKA 3UA9A 4BUWA 4GNLA 4GNQA 4MSKA 4TK5A 3CE0A 3KCZA 4HMHA 5ECEA 4TKGA 4UVOA 3L3LA 4L7PA 1KHEA 4L0IA 4HLMA 1EFYA 3PAXA 4WOUA 4PNSA 5LXPA 5ETYA 4ZZZA 3MOFA 3MHJA 4IUEA 1PAXA 4J1ZA 2GMVA 4TJWA 4OQAC 5FH1A 5C5PA 4L7RA 1KHBA 4GNPA 4GMWA 4GMUA 4M7BA 4TVJA 4WPVA 3W51A 4ZZXA 2PXZX 5FH0A 3KJDA 3P0NA 4WL8A 4HKIA 4PNTA 4HLHA 4N3RA 5FH2A 1II2A 4DVIA 1YGGA 1AQ2A 5AL3A 4LI7A 3DT7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BUU A;  4BUX A;  4BUV A;  4W6E A;  1GS0 A;  4BUE A;  5ADQ A;  3UH4 A;  4L70 A;  4UVX A;  4BS4 A;  4UFU A;  4HL5 A;  2X5Y A;  5C5Q A;  4L6Z A;  4K4E A;  4TJU A;  3P0Q A;  3KR7 A;  4HLK A;  4F1L A;  4GV4 A;  3UA9 A;  4BUW A;  3KR8 A;  4BU7 A;  4KZQ A;  5LX6 A;  5EBT A;  4F0E A;  4GV0 A;  4J21 A;  4LI6 A;  4TOR A;  4UVZ A;  4N4V A;  4UUH A;  4MSK A;  4TK5 A;  5C5R A;  4BUI A;  4PNL A;  3CE0 A;  2RD6 A;  3KCZ A;  4HMH A;  4UI4 A;  2PAX A;  4UI7 A;  4W5I A;  2CR9 A;  3UH2 A;  5ECE A;  4TKG A;  4OA7 A;  4UI8 A;  4UI3 A;  4UVO A;  4HHZ A;  3L3L A;  4L7P A;  5AKU A;  4BUD A;  5FPF A;  4L7L A;  4L0I A;  4HLM A;  5AL1 A;  4UVN A;  1EFY A;  4HHY A;  4X52 A;  3BLJ A;  3PAX A;  4L33 A;  4LI8 A;  4KRS A;  4BUY A;  4GV2 A;  4UI6 A;  3C49 A;  4UFY A;  4DQY C;  2PQF A;  4PNS A;  3SMJ A;  3U9Y A;  4UVT A;  1UK0 A;  5AL4 A;  4PAX A;  5LXP A;  4UVL A;  5ETY A;  5A00 A;  4HKN A;  4ZZZ A;  4J3L A;  4L2F A;  5ADS A;  3GN7 A;  4UHG A;  3MHJ A;  4N4T A;  4OPX C;  4IUE A;  4L0B A;  3FHB A;  4BU6 A;  4BU5 A;  4HLG A;  4TKI A;  4PNQ A;  3HKV A;  4KZL A;  4L0T A;  4TJY A;  1PAX A;  4J1Z A;  4UXB A;  3SMI A;  4TJW A;  4AVW A;  4HKK A;  4L31 A;  4L7N A;  4UVU A;  4AVU A;  4BU9 A;  4PJV A;  4I9I A;  4OQA C;  2RA8 A;  4MSG A;  4GV7 A;  5DCZ A;  5C5P A;  4L7R A;  4BFP A;  4OQB C;  4J22 A;  4BU3 A;  3P0P A;  5AKW A;  4BUA A;  2PAW A;  4W5S A;  4L7O A;  1UK1 A;  4BUS A;  5ADT A;  1WOK A;  3C4H A;  4M7B A;  4TVJ A;  4BUF A;  2EOC A;  4PNR A;  3GJW A;  3L3M A;  4R5W A;  3W51 A;  4L0S A;  4ZZX A;  4F1Q A;  4BUT A;  2RCW A;  4PJT A;  4PML A;  4L7U A;  4BU8 A;  4L34 A;  4UI5 A;  4UND A;  4PY4 A;  4KZU A;  3KJD A;  4UW1 A;  5ADR A;  4L0V A;  3P0N A;  3U9H A;  4UVV A;  4UX4 A;  3SE2 A;  4L2K A;  4MT9 A;  4HKI A;  4TKF A;  4L32 A;  4U6A A;  4UVP A;  5AEH A;  1A26 A;  4PNT A;  4TK0 A;  4J3M A;  4L2G A;  4PNM A;  4HLH A;  3GEY A;  3MHK A;  4HYF A;  4N3R A;  4PNN A;  4TOS A;  4L10 A;  5AL2 A;  4UVY A;  5AL5 A;  4BJ9 A;  4UVS A;  4BJC A;  4DVI A;  2RF5 A;  5AL3 A;  4L09 A;  4UVW A;  3UDD A;  5LYH A;  4HLF A;  3GOY A;  4LI7 A;  4BJB A;  4ZZY A;  4XHU A;  4K4F A;  5FPG A;  4RV6 A;  4L6S A;  4R6E A; 
#chains in the Genus database with same CATH topology
 4BUU A;  4BUV A;  4BS4 A;  4HL5 A;  2X5Y A;  5C5Q A;  4F1L A;  4KZQ A;  5LX6 A;  4J21 A;  4LI6 A;  2RD6 A;  1OEN A;  4W5I A;  4UI7 A;  2PAX A;  1OS1 A;  4YW9 A;  5AKU A;  5AL1 A;  3BLJ A;  4L33 A;  2PC9 A;  2PQF A;  5FH4 A;  4UVT A;  2FAF A;  4UVL A;  4HKN A;  4J3L A;  4L2F A;  5ADS A;  4BU6 A;  4BU5 A;  4TKI A;  4TJY A;  3SMI A;  4HKK A;  4AVU A;  4BU9 A;  4I9I A;  4MSG A;  5AKW A;  4BUA A;  4W5S A;  2RKA A;  3DTB A;  4BUS A;  4YWD A;  1WOK A;  4PNR A;  3GJW A;  1K3C A;  4F1Q A;  4UI5 A;  4UND A;  4PY4 A;  3DT4 A;  3U9H A;  4UVV A;  4UX4 A;  2QZY A;  4PNM A;  3MHK A;  2RKE A;  4YWB A;  4UVY A;  5AL5 A;  5LYH A;  1YTM A;  4JNG A;  4GMZ A;  4BJB A;  4XHU A;  4J1J A;  5FPG A;  4L0S A;  4RV6 A;  5FPF A;  4BUX A;  4BUE A;  3UH4 A;  4UVX A;  2QEW A;  4UFU A;  4OX2 A;  3KR8 A;  1YLH A;  3ZLA A;  2ZCI A;  4GV0 A;  5C5R A;  4UUH A;  4J1G A;  4BUI A;  1KHF A;  2CR9 A;  3UH2 A;  4UI8 A;  4HHZ A;  4BUD A;  4L7L A;  4UVN A;  4X52 A;  4HHY A;  2QF1 A;  1XKV A;  4LI8 A;  4WPU A;  4GV2 A;  4UI6 A;  3C49 A;  4UFY A;  2HZM A;  3SMJ A;  2OLQ A;  1J3B A;  1UK0 A;  4PAX A;  5A00 A;  2RK7 A;  4L0B A;  3FHB A;  4KZL A;  4UXB A;  4AVW A;  4L7N A;  4UVU A;  4PJV A;  4GNO A;  5DCZ A;  5FH5 A;  4OQB C;  4J22 A;  3P0P A;  1UK1 A;  4RCG A;  2QEY A;  4BUF A;  2EOC A;  2HZS A;  4BUT A;  2RCW A;  4PJT A;  4PML A;  4L7U A;  4L34 A;  4KZU A;  5ADR A;  4L0V A;  4WIU A;  3SE2 A;  4L2K A;  4U6A A;  4UVP A;  4PNN A;  4L10 A;  4BJC A;  4UVS A;  2RF5 A;  4L09 A;  4UVW A;  4HLF A;  4K4F A;  4R6E A;  4R43 A;  4W6E A;  1GS0 A;  5ADQ A;  2RKD A;  3KR7 A;  4GV4 A;  4BU7 A;  1M51 A;  5EBT A;  4F0E A;  1KHG A;  4TOR A;  4UVZ A;  4N4V A;  4PNL A;  4UI4 A;  4OA7 A;  4UI3 A;  3MOE A;  4KRS A;  4BUY A;  3MOH A;  4DQY C;  3U9Y A;  2RK8 A;  4IDU A;  3DT2 A;  3GN7 A;  4UHG A;  4BHH B;  4N4T A;  4OPX C;  5I67 A;  4YW8 A;  4HLG A;  2QF2 A;  1K3D A;  3HKV A;  4PNQ A;  4L0T A;  4L31 A;  2FAH A;  2RA8 A;  4GMM A;  4GV7 A;  2PY7 X;  4BFP A;  4BU3 A;  2PAW A;  4L7O A;  5ADT A;  3C4H A;  4GNM A;  3L3M A;  4R5W A;  1YVY A;  4WIE A;  4BU8 A;  4UW1 A;  3ZL9 A;  4MT9 A;  4TKF A;  4L32 A;  5AEH A;  1A26 A;  4TK0 A;  4J3M A;  4L2G A;  3GEY A;  4HYF A;  4TOS A;  5AL2 A;  1NHX A;  4BJ9 A;  3UDD A;  3GOY A;  4WPT A;  4ZZY A;  5AL4 A;  4L6S A;  5FH3 A;  4IDX A;  4L70 A;  2OLR A;  1AYL A;  4L6Z A;  4K4E A;  4TJU A;  3P0Q A;  4HLK A;  3UA9 A;  4BUW A;  4GNL A;  4GNQ A;  4MSK A;  4TK5 A;  4IDU B;  3CE0 A;  3KCZ A;  4HMH A;  5ECE A;  4TKG A;  4UVO A;  4BGP A;  3L3L A;  4L7P A;  1KHE A;  4L0I A;  4HLM A;  1EFY A;  3PAX A;  4WOU A;  4PNS A;  5LXP A;  5ETY A;  4ZZZ A;  3MOF A;  3MHJ A;  4IUE A;  1PAX A;  4J1Z A;  2GMV A;  4TJW A;  4IJS A;  4OQA C;  5FH1 A;  5C5P A;  4L7R A;  1KHB A;  4GNP A;  4GMW A;  4GMU A;  4M7B A;  4TVJ A;  4WPV A;  3W51 A;  4ZZX A;  2PXZ X;  5FH0 A;  3KJD A;  3P0N A;  4WL8 A;  4HKI A;  4PNT A;  4HLH A;  4N3R A;  5FH2 A;  1II2 A;  4DVI A;  1YGG A;  1AQ2 A;  5AL3 A;  4LI7 A;  3DT7 A; 
#chains in the Genus database with same CATH homology
 4BUU A;  4BUV A;  4BS4 A;  4HL5 A;  2X5Y A;  5C5Q A;  4F1L A;  4KZQ A;  5LX6 A;  4J21 A;  4LI6 A;  2RD6 A;  1OEN A;  4W5I A;  4UI7 A;  2PAX A;  1OS1 A;  4YW9 A;  5AKU A;  5AL1 A;  3BLJ A;  4L33 A;  2PC9 A;  2PQF A;  5FH4 A;  4UVT A;  2FAF A;  4UVL A;  4HKN A;  4J3L A;  4L2F A;  5ADS A;  4BU6 A;  4BU5 A;  4TKI A;  4TJY A;  3SMI A;  4HKK A;  4AVU A;  4BU9 A;  4I9I A;  4MSG A;  5AKW A;  4BUA A;  4W5S A;  2RKA A;  3DTB A;  4BUS A;  4YWD A;  1WOK A;  4PNR A;  3GJW A;  1K3C A;  4F1Q A;  4UI5 A;  4UND A;  4PY4 A;  3DT4 A;  3U9H A;  4UVV A;  4UX4 A;  2QZY A;  4PNM A;  3MHK A;  2RKE A;  4YWB A;  4UVY A;  5AL5 A;  5LYH A;  1YTM A;  4GMZ A;  4BJB A;  4XHU A;  5FPG A;  4L0S A;  4RV6 A;  5FPF A;  4BUX A;  4BUE A;  3UH4 A;  4UVX A;  2QEW A;  4UFU A;  4OX2 A;  3KR8 A;  1YLH A;  2ZCI A;  4GV0 A;  5C5R A;  4UUH A;  4BUI A;  1KHF A;  2CR9 A;  3UH2 A;  4UI8 A;  4HHZ A;  4BUD A;  4L7L A;  4UVN A;  4X52 A;  4HHY A;  2QF1 A;  1XKV A;  4LI8 A;  4WPU A;  4GV2 A;  4UI6 A;  3C49 A;  4UFY A;  3SMJ A;  2OLQ A;  1J3B A;  1UK0 A;  4PAX A;  5A00 A;  2RK7 A;  4L0B A;  3FHB A;  4KZL A;  4UXB A;  4AVW A;  4L7N A;  4UVU A;  4PJV A;  4GNO A;  5DCZ A;  5FH5 A;  4OQB C;  4J22 A;  3P0P A;  1UK1 A;  4RCG A;  2QEY A;  4BUF A;  2EOC A;  4BUT A;  2RCW A;  4PJT A;  4PML A;  4L7U A;  4L34 A;  4KZU A;  5ADR A;  4L0V A;  4WIU A;  3SE2 A;  4L2K A;  4U6A A;  4UVP A;  4PNN A;  4L10 A;  4BJC A;  4UVS A;  2RF5 A;  4L09 A;  4UVW A;  4HLF A;  4K4F A;  4R6E A;  4R43 A;  4W6E A;  1GS0 A;  5ADQ A;  2RKD A;  3KR7 A;  4GV4 A;  4BU7 A;  1M51 A;  5EBT A;  4F0E A;  1KHG A;  4TOR A;  4UVZ A;  4N4V A;  4PNL A;  4UI4 A;  4OA7 A;  4UI3 A;  3MOE A;  4KRS A;  4BUY A;  3MOH A;  4DQY C;  3U9Y A;  2RK8 A;  3DT2 A;  3GN7 A;  4UHG A;  4N4T A;  4OPX C;  5I67 A;  4YW8 A;  4HLG A;  2QF2 A;  1K3D A;  3HKV A;  4PNQ A;  4L0T A;  4L31 A;  2FAH A;  2RA8 A;  4GMM A;  4GV7 A;  2PY7 X;  4BFP A;  4BU3 A;  2PAW A;  4L7O A;  5ADT A;  3C4H A;  4GNM A;  3L3M A;  4R5W A;  1YVY A;  4WIE A;  4BU8 A;  4UW1 A;  4MT9 A;  4TKF A;  4L32 A;  5AEH A;  1A26 A;  4TK0 A;  4J3M A;  4L2G A;  3GEY A;  4HYF A;  4TOS A;  5AL2 A;  1NHX A;  4BJ9 A;  3UDD A;  3GOY A;  4WPT A;  4ZZY A;  5AL4 A;  4L6S A;  5FH3 A;  4L70 A;  2OLR A;  1AYL A;  4L6Z A;  4K4E A;  4TJU A;  3P0Q A;  4HLK A;  3UA9 A;  4BUW A;  4GNL A;  4GNQ A;  4MSK A;  4TK5 A;  3CE0 A;  3KCZ A;  4HMH A;  5ECE A;  4TKG A;  4UVO A;  3L3L A;  4L7P A;  1KHE A;  4L0I A;  4HLM A;  1EFY A;  3PAX A;  4WOU A;  4PNS A;  5LXP A;  5ETY A;  4ZZZ A;  3MOF A;  3MHJ A;  4IUE A;  1PAX A;  4J1Z A;  2GMV A;  4TJW A;  4OQA C;  5FH1 A;  5C5P A;  4L7R A;  1KHB A;  4GNP A;  4GMW A;  4GMU A;  4M7B A;  4TVJ A;  4WPV A;  3W51 A;  4ZZX A;  2PXZ X;  5FH0 A;  3KJD A;  3P0N A;  4WL8 A;  4HKI A;  4PNT A;  4HLH A;  4N3R A;  5FH2 A;  1II2 A;  4DVI A;  1YGG A;  1AQ2 A;  5AL3 A;  4LI7 A;  3DT7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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