1GK0A

Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin c
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
153
structure length
153
Chain Sequence
QAPIAAYKPRSNEILWDGYGVPHIYGVDAPSAFYGYGWAQARSHGDNILRLYGEARGKGAEYWGPDYEQTTVWLLTNGVPERAQQWYAQQSPDFRANLDAFAAGINAYAQQNPDDISPEVRQVLPVSGADVVAHAHRLMNFLYVASPGRTLGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Prediction of Modifications in Glutarylamidase to Allow Single-Step Enzymatic Production of 7-Aminocephalosporanic Acid from Cephalosporin C.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas sp.
molecule keywords CEPHALOSPORIN ACYLASE
total genus 49
structure length 153
sequence length 153
chains with identical sequence C
ec nomenclature ec 3.5.1.93: Glutaryl-7-aminocephalosporanic-acid acylase.
pdb deposition date 2001-08-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.439.10 Mainly Alpha Orthogonal Bundle Penicillin Amidohydrolase; domain 1 Penicillin Amidohydrolase, domain 1 1gk0A00
1AI4A 4HSRA 1AJNA 1JVZA 2AE4A 3K3WA 1K7DA 3JTQA 3JTRA 1K5QA 3L94A 4E56A 1PNLA 1FXHA 1KECA 1AJQA 2WYEA 4WKUA 4E55A 1FM2A 1GK9A 4HSTA 1AJPA 2WYDA 1K5SA 3L91A 4WKVA 2ADVA 2WYBA 2AE3A 3SRBA 1GHDA 4E57A 1FXVA 1AI5A 3S8RA 1AI6A 4BTHA 1OR0A 2WYCA 1GM9A 1JW0A 1GM7A 4YF9A 1KEHA 2AE5A 1GK1A 1PNKA 1PNMA 3SRAA 1H2GA 4YFAA 4WKTA 1GKFA 4K2GA 4PEMA 4PELA 3SRCA 3ML0A 4K2FA 1GM8A 4YFBA 1AI7A 1GK0A 4M1JA 1E3AA 1CP9A 1JX9A 4WKSA
chains in the Genus database with same CATH superfamily
1AI4A 4HSRA 1AJNA 1JVZA 2AE4A 3K3WA 1K7DA 3JTQA 3JTRA 1K5QA 3L94A 4E56A 1PNLA 1FXHA 1KECA 1AJQA 2WYEA 4WKUA 4E55A 1FM2A 1GK9A 4HSTA 1AJPA 2WYDA 1K5SA 3L91A 4WKVA 4BWCA 2ADVA 2WYBA 2AE3A 3SRBA 1GHDA 4E57A 1FXVA 1AI5A 3S8RA 1AI6A 4BTHA 1OR0A 2WYCA 1GM9A 1JW0A 1GM7A 4YF9A 1KEHA 2AE5A 1GK1A 1PNKA 3FGTA 1PNMA 3SRAA 1H2GA 4YFAA 4WKTA 1GKFA 4K2GA 3FGRA 4PEMA 4PELA 3SRCA 3ML0A 4K2FA 1GM8A 4YFBA 1AI7A 1GK0A 4M1JA 1E3AA 1CP9A 1JX9A 4WKSA
chains in the Genus database with same CATH topology
1AI4A 4HSRA 1AJNA 1JVZA 2AE4A 3K3WA 1K7DA 3JTQA 3JTRA 1K5QA 3L94A 4E56A 1PNLA 1FXHA 1KECA 1AJQA 2WYEA 4WKUA 4E55A 1FM2A 1GK9A 4HSTA 1AJPA 2WYDA 1K5SA 3L91A 4WKVA 2ADVA 2WYBA 2AE3A 3SRBA 1GHDA 4E57A 1FXVA 1AI5A 3S8RA 1AI6A 4BTHA 1OR0A 2WYCA 1GM9A 1JW0A 1GM7A 4YF9A 1KEHA 2AE5A 1GK1A 1PNKA 1PNMA 3SRAA 1H2GA 4YFAA 4WKTA 1GKFA 4K2GA 4PEMA 4PELA 3SRCA 3ML0A 4K2FA 1GM8A 4YFBA 1AI7A 1GK0A 4M1JA 1E3AA 1CP9A 1JX9A 4WKSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AI4 A;  4HSR A;  1AJN A;  1JVZ A;  2AE4 A;  3K3W A;  1K7D A;  3JTQ A;  3JTR A;  1K5Q A;  3L94 A;  4E56 A;  1PNL A;  1FXH A;  1KEC A;  1AJQ A;  2WYE A;  4WKU A;  4E55 A;  1FM2 A;  1GK9 A;  4HST A;  1AJP A;  2WYD A;  1K5S A;  3L91 A;  4WKV A;  2ADV A;  2WYB A;  2AE3 A;  3SRB A;  1GHD A;  4E57 A;  1FXV A;  1AI5 A;  3S8R A;  1AI6 A;  4BTH A;  1OR0 A;  2WYC A;  1GM9 A;  1JW0 A;  1GM7 A;  4YF9 A;  1KEH A;  2AE5 A;  1GK1 A;  1PNK A;  1PNM A;  3SRA A;  1H2G A;  4YFA A;  4WKT A;  1GKF A;  4K2G A;  4PEM A;  4PEL A;  3SRC A;  3ML0 A;  4K2F A;  1GM8 A;  4YFB A;  1AI7 A;  1GK0 A;  4M1J A;  1E3A A;  1CP9 A;  1JX9 A;  4WKS A; 
#chains in the Genus database with same CATH topology
 1AI4 A;  4HSR A;  1AJN A;  1JVZ A;  2AE4 A;  3K3W A;  1K7D A;  3JTQ A;  3JTR A;  1K5Q A;  3L94 A;  4E56 A;  1PNL A;  1FXH A;  1KEC A;  1AJQ A;  2WYE A;  4WKU A;  4E55 A;  1FM2 A;  1GK9 A;  4HST A;  1AJP A;  2WYD A;  1K5S A;  3L91 A;  4WKV A;  4BWC A;  2ADV A;  2WYB A;  2AE3 A;  3SRB A;  1GHD A;  4E57 A;  1FXV A;  1AI5 A;  3S8R A;  1AI6 A;  4BTH A;  1OR0 A;  2WYC A;  1GM9 A;  1JW0 A;  1GM7 A;  4YF9 A;  1KEH A;  2AE5 A;  1GK1 A;  1PNK A;  3FGT A;  1PNM A;  3SRA A;  1H2G A;  4YFA A;  4WKT A;  1GKF A;  4K2G A;  3FGR A;  4PEM A;  4PEL A;  3SRC A;  3ML0 A;  4K2F A;  1GM8 A;  4YFB A;  1AI7 A;  1GK0 A;  4M1J A;  1E3A A;  1CP9 A;  1JX9 A;  4WKS A; 
#chains in the Genus database with same CATH homology
 1AI4 A;  4HSR A;  1AJN A;  1JVZ A;  2AE4 A;  3K3W A;  1K7D A;  3JTQ A;  3JTR A;  1K5Q A;  3L94 A;  4E56 A;  1PNL A;  1FXH A;  1KEC A;  1AJQ A;  2WYE A;  4WKU A;  4E55 A;  1FM2 A;  1GK9 A;  4HST A;  1AJP A;  2WYD A;  1K5S A;  3L91 A;  4WKV A;  2ADV A;  2WYB A;  2AE3 A;  3SRB A;  1GHD A;  4E57 A;  1FXV A;  1AI5 A;  3S8R A;  1AI6 A;  4BTH A;  1OR0 A;  2WYC A;  1GM9 A;  1JW0 A;  1GM7 A;  4YF9 A;  1KEH A;  2AE5 A;  1GK1 A;  1PNK A;  1PNM A;  3SRA A;  1H2G A;  4YFA A;  4WKT A;  1GKF A;  4K2G A;  4PEM A;  4PEL A;  3SRC A;  3ML0 A;  4K2F A;  1GM8 A;  4YFB A;  1AI7 A;  1GK0 A;  4M1J A;  1E3A A;  1CP9 A;  1JX9 A;  4WKS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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