1GK0A

Structure-based prediction of modifications in glutarylamidase to allow single-step enzymatic production of 7-aminocephalosporanic acid from cephalosporin c
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
153
structure length
153
Chain Sequence
QAPIAAYKPRSNEILWDGYGVPHIYGVDAPSAFYGYGWAQARSHGDNILRLYGEARGKGAEYWGPDYEQTTVWLLTNGVPERAQQWYAQQSPDFRANLDAFAAGINAYAQQNPDDISPEVRQVLPVSGADVVAHAHRLMNFLYVASPGRTLGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Pseudomonas sp.
publication title Structure-Based Prediction of Modifications in Glutarylamidase to Allow Single-Step Enzymatic Production of 7-Aminocephalosporanic Acid from Cephalosporin C.
pubmed doi rcsb
molecule keywords CEPHALOSPORIN ACYLASE
total genus 49
structure length 153
sequence length 153
chains with identical sequence C
ec nomenclature ec 3.5.1.93: Glutaryl-7-aminocephalosporanic-acid acylase.
pdb deposition date 2001-08-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.439.10 Mainly Alpha Orthogonal Bundle Penicillin Amidohydrolase; domain 1 Penicillin Amidohydrolase, domain 1 1gk0A00
1AJQA 3JTRA 4YFBA 4YFAA 1JX9A 1GK1A 1K5QA 1KEHA 4PELA 4YF9A 4M1JA 3SRBA 3ML0A 1FM2A 1FXVA 1E3AA 3L94A 1H2GA 1GK0A 1CP9A 1JW0A 2AE5A 1AI5A 2WYBA 2WYEA 4WKTA 1AJNA 4E57A 4HSTA 3K3WA 1GHDA 1PNLA 4WKUA 4WKVA 4BTHA 1GKFA 4PEMA 1AI6A 1AI4A 1K7DA 3L91A 2WYDA 4E56A 4E55A 1AJPA 1GM9A 2AE4A 1K5SA 4K2FA 1JVZA 3S8RA 4K2GA 1AI7A 3SRCA 1OR0A 2AE3A 1KECA 3JTQA 4WKSA 1GM7A 1FXHA 4HSRA 2ADVA 1PNKA 3SRAA 1GK9A 2WYCA 1PNMA 1GM8A
chains in the Genus database with same CATH superfamily
4BWCA 1AJQA 3JTRA 3FGTA 4YFBA 4YFAA 1JX9A 1GK1A 1K5QA 1KEHA 4PELA 4YF9A 4M1JA 3SRBA 3ML0A 1FM2A 1FXVA 1E3AA 3L94A 1H2GA 1GK0A 1CP9A 3FGRA 1JW0A 2AE5A 1AI5A 2WYBA 2WYEA 4WKTA 1AJNA 4E57A 4HSTA 3K3WA 1GHDA 1PNLA 4WKUA 4WKVA 4BTHA 1GKFA 4PEMA 1AI6A 1AI4A 1K7DA 3L91A 2WYDA 4E56A 4E55A 1AJPA 1GM9A 2AE4A 1K5SA 4K2FA 1JVZA 3S8RA 4K2GA 1AI7A 3SRCA 1OR0A 2AE3A 1KECA 3JTQA 4WKSA 1GM7A 1FXHA 4HSRA 2ADVA 1PNKA 3SRAA 1GK9A 2WYCA 1PNMA 1GM8A
chains in the Genus database with same CATH topology
1AJQA 3JTRA 4YFBA 4YFAA 1JX9A 1GK1A 1K5QA 1KEHA 4PELA 4YF9A 4M1JA 3SRBA 3ML0A 1FM2A 1FXVA 1E3AA 3L94A 1H2GA 1GK0A 1CP9A 1JW0A 2AE5A 1AI5A 2WYBA 2WYEA 4WKTA 1AJNA 4E57A 4HSTA 3K3WA 1GHDA 1PNLA 4WKUA 4WKVA 4BTHA 1GKFA 4PEMA 1AI6A 1AI4A 1K7DA 3L91A 2WYDA 4E56A 4E55A 1AJPA 1GM9A 2AE4A 1K5SA 4K2FA 1JVZA 3S8RA 4K2GA 1AI7A 3SRCA 1OR0A 2AE3A 1KECA 3JTQA 4WKSA 1GM7A 1FXHA 4HSRA 2ADVA 1PNKA 3SRAA 1GK9A 2WYCA 1PNMA 1GM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AJQ A;  3JTR A;  4YFB A;  4YFA A;  1JX9 A;  1GK1 A;  1K5Q A;  1KEH A;  4PEL A;  4YF9 A;  4M1J A;  3SRB A;  3ML0 A;  1FM2 A;  1FXV A;  1E3A A;  3L94 A;  1H2G A;  1GK0 A;  1CP9 A;  1JW0 A;  2AE5 A;  1AI5 A;  2WYB A;  2WYE A;  4WKT A;  1AJN A;  4E57 A;  4HST A;  3K3W A;  1GHD A;  1PNL A;  4WKU A;  4WKV A;  4BTH A;  1GKF A;  4PEM A;  1AI6 A;  1AI4 A;  1K7D A;  3L91 A;  2WYD A;  4E56 A;  4E55 A;  1AJP A;  1GM9 A;  2AE4 A;  1K5S A;  4K2F A;  1JVZ A;  3S8R A;  4K2G A;  1AI7 A;  3SRC A;  1OR0 A;  2AE3 A;  1KEC A;  3JTQ A;  4WKS A;  1GM7 A;  1FXH A;  4HSR A;  2ADV A;  1PNK A;  3SRA A;  1GK9 A;  2WYC A;  1PNM A;  1GM8 A; 
#chains in the Genus database with same CATH topology
 4BWC A;  1AJQ A;  3JTR A;  3FGT A;  4YFB A;  4YFA A;  1JX9 A;  1GK1 A;  1K5Q A;  1KEH A;  4PEL A;  4YF9 A;  4M1J A;  3SRB A;  3ML0 A;  1FM2 A;  1FXV A;  1E3A A;  3L94 A;  1H2G A;  1GK0 A;  1CP9 A;  3FGR A;  1JW0 A;  2AE5 A;  1AI5 A;  2WYB A;  2WYE A;  4WKT A;  1AJN A;  4E57 A;  4HST A;  3K3W A;  1GHD A;  1PNL A;  4WKU A;  4WKV A;  4BTH A;  1GKF A;  4PEM A;  1AI6 A;  1AI4 A;  1K7D A;  3L91 A;  2WYD A;  4E56 A;  4E55 A;  1AJP A;  1GM9 A;  2AE4 A;  1K5S A;  4K2F A;  1JVZ A;  3S8R A;  4K2G A;  1AI7 A;  3SRC A;  1OR0 A;  2AE3 A;  1KEC A;  3JTQ A;  4WKS A;  1GM7 A;  1FXH A;  4HSR A;  2ADV A;  1PNK A;  3SRA A;  1GK9 A;  2WYC A;  1PNM A;  1GM8 A; 
#chains in the Genus database with same CATH homology
 1AJQ A;  3JTR A;  4YFB A;  4YFA A;  1JX9 A;  1GK1 A;  1K5Q A;  1KEH A;  4PEL A;  4YF9 A;  4M1J A;  3SRB A;  3ML0 A;  1FM2 A;  1FXV A;  1E3A A;  3L94 A;  1H2G A;  1GK0 A;  1CP9 A;  1JW0 A;  2AE5 A;  1AI5 A;  2WYB A;  2WYE A;  4WKT A;  1AJN A;  4E57 A;  4HST A;  3K3W A;  1GHD A;  1PNL A;  4WKU A;  4WKV A;  4BTH A;  1GKF A;  4PEM A;  1AI6 A;  1AI4 A;  1K7D A;  3L91 A;  2WYD A;  4E56 A;  4E55 A;  1AJP A;  1GM9 A;  2AE4 A;  1K5S A;  4K2F A;  1JVZ A;  3S8R A;  4K2G A;  1AI7 A;  3SRC A;  1OR0 A;  2AE3 A;  1KEC A;  3JTQ A;  4WKS A;  1GM7 A;  1FXH A;  4HSR A;  2ADV A;  1PNK A;  3SRA A;  1GK9 A;  2WYC A;  1PNM A;  1GM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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