2WYEA

The quorum quenching n-acyl homoserine lactone acylase pvdq is an ntn- hydrolase with an unusual substrate-binding pocket
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
164
structure length
164
Chain Sequence
TGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT ALPHA
publication title The Quorum-Quenching N-Acyl Homoserine Lactone Acylase Pvdq is an Ntn-Hydrolase with an Unusual Substrate-Binding Pocket
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 55
structure length 164
sequence length 164
ec nomenclature ec 3.5.1.97: Acyl-homoserine-lactone acylase.
pdb deposition date 2009-11-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.439.10 Mainly Alpha Orthogonal Bundle Penicillin Amidohydrolase; domain 1 Penicillin Amidohydrolase, domain 1 2wyeA00
3JTQA 3SRBA 3L91A 1JW0A 1JX9A 4E57A 1K7DA 1KECA 4K2GA 1AI6A 1GHDA 3SRCA 1GM8A 4HSRA 4WKSA 4WKTA 1PNKA 1CP9A 2WYCA 1KEHA 2WYEA 1AI7A 4HSTA 2AE4A 4WKVA 1FXVA 1GK9A 1AJNA 1GK1A 4E55A 4BTHA 4E56A 3SRAA 4M1JA 2WYBA 1H2GA 3L94A 1AI4A 1AI5A 2AE5A 1GKFA 3K3WA 4YFAA 1AJPA 3ML0A 3S8RA 1GM9A 1PNMA 1E3AA 1K5SA 1FM2A 4WKUA 4PELA 1PNLA 4YF9A 1FXHA 2AE3A 4K2FA 2ADVA 1OR0A 4PEMA 1GK0A 3JTRA 4YFBA 1AJQA 1K5QA 1GM7A 1JVZA 2WYDA
chains in the Genus database with same CATH superfamily
3JTQA 3SRBA 3L91A 1JW0A 1JX9A 4E57A 1K7DA 1KECA 4K2GA 1AI6A 1GHDA 3FGRA 3SRCA 1GM8A 4HSRA 4WKSA 4WKTA 1PNKA 1CP9A 2WYCA 1KEHA 2WYEA 1AI7A 4HSTA 2AE4A 4WKVA 1FXVA 1GK9A 1AJNA 1GK1A 4E55A 4BTHA 4E56A 3SRAA 4BWCA 4M1JA 2WYBA 1H2GA 3L94A 1AI4A 1AI5A 2AE5A 1GKFA 3K3WA 4YFAA 1AJPA 3ML0A 3S8RA 1GM9A 1PNMA 1E3AA 1K5SA 1FM2A 4WKUA 4PELA 1PNLA 4YF9A 3FGTA 1FXHA 2AE3A 4K2FA 2ADVA 1OR0A 4PEMA 1GK0A 3JTRA 4YFBA 1AJQA 1K5QA 1GM7A 1JVZA 2WYDA
chains in the Genus database with same CATH topology
3JTQA 3SRBA 3L91A 1JW0A 1JX9A 4E57A 1K7DA 1KECA 4K2GA 1AI6A 1GHDA 3SRCA 1GM8A 4HSRA 4WKSA 4WKTA 1PNKA 1CP9A 2WYCA 1KEHA 2WYEA 1AI7A 4HSTA 2AE4A 4WKVA 1FXVA 1GK9A 1AJNA 1GK1A 4E55A 4BTHA 4E56A 3SRAA 4M1JA 2WYBA 1H2GA 3L94A 1AI4A 1AI5A 2AE5A 1GKFA 3K3WA 4YFAA 1AJPA 3ML0A 3S8RA 1GM9A 1PNMA 1E3AA 1K5SA 1FM2A 4WKUA 4PELA 1PNLA 4YF9A 1FXHA 2AE3A 4K2FA 2ADVA 1OR0A 4PEMA 1GK0A 3JTRA 4YFBA 1AJQA 1K5QA 1GM7A 1JVZA 2WYDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JTQ A;  3SRB A;  3L91 A;  1JW0 A;  1JX9 A;  4E57 A;  1K7D A;  1KEC A;  4K2G A;  1AI6 A;  1GHD A;  3SRC A;  1GM8 A;  4HSR A;  4WKS A;  4WKT A;  1PNK A;  1CP9 A;  2WYC A;  1KEH A;  2WYE A;  1AI7 A;  4HST A;  2AE4 A;  4WKV A;  1FXV A;  1GK9 A;  1AJN A;  1GK1 A;  4E55 A;  4BTH A;  4E56 A;  3SRA A;  4M1J A;  2WYB A;  1H2G A;  3L94 A;  1AI4 A;  1AI5 A;  2AE5 A;  1GKF A;  3K3W A;  4YFA A;  1AJP A;  3ML0 A;  3S8R A;  1GM9 A;  1PNM A;  1E3A A;  1K5S A;  1FM2 A;  4WKU A;  4PEL A;  1PNL A;  4YF9 A;  1FXH A;  2AE3 A;  4K2F A;  2ADV A;  1OR0 A;  4PEM A;  1GK0 A;  3JTR A;  4YFB A;  1AJQ A;  1K5Q A;  1GM7 A;  1JVZ A;  2WYD A; 
#chains in the Genus database with same CATH topology
 3JTQ A;  3SRB A;  3L91 A;  1JW0 A;  1JX9 A;  4E57 A;  1K7D A;  1KEC A;  4K2G A;  1AI6 A;  1GHD A;  3FGR A;  3SRC A;  1GM8 A;  4HSR A;  4WKS A;  4WKT A;  1PNK A;  1CP9 A;  2WYC A;  1KEH A;  2WYE A;  1AI7 A;  4HST A;  2AE4 A;  4WKV A;  1FXV A;  1GK9 A;  1AJN A;  1GK1 A;  4E55 A;  4BTH A;  4E56 A;  3SRA A;  4BWC A;  4M1J A;  2WYB A;  1H2G A;  3L94 A;  1AI4 A;  1AI5 A;  2AE5 A;  1GKF A;  3K3W A;  4YFA A;  1AJP A;  3ML0 A;  3S8R A;  1GM9 A;  1PNM A;  1E3A A;  1K5S A;  1FM2 A;  4WKU A;  4PEL A;  1PNL A;  4YF9 A;  3FGT A;  1FXH A;  2AE3 A;  4K2F A;  2ADV A;  1OR0 A;  4PEM A;  1GK0 A;  3JTR A;  4YFB A;  1AJQ A;  1K5Q A;  1GM7 A;  1JVZ A;  2WYD A; 
#chains in the Genus database with same CATH homology
 3JTQ A;  3SRB A;  3L91 A;  1JW0 A;  1JX9 A;  4E57 A;  1K7D A;  1KEC A;  4K2G A;  1AI6 A;  1GHD A;  3SRC A;  1GM8 A;  4HSR A;  4WKS A;  4WKT A;  1PNK A;  1CP9 A;  2WYC A;  1KEH A;  2WYE A;  1AI7 A;  4HST A;  2AE4 A;  4WKV A;  1FXV A;  1GK9 A;  1AJN A;  1GK1 A;  4E55 A;  4BTH A;  4E56 A;  3SRA A;  4M1J A;  2WYB A;  1H2G A;  3L94 A;  1AI4 A;  1AI5 A;  2AE5 A;  1GKF A;  3K3W A;  4YFA A;  1AJP A;  3ML0 A;  3S8R A;  1GM9 A;  1PNM A;  1E3A A;  1K5S A;  1FM2 A;  4WKU A;  4PEL A;  1PNL A;  4YF9 A;  1FXH A;  2AE3 A;  4K2F A;  2ADV A;  1OR0 A;  4PEM A;  1GK0 A;  3JTR A;  4YFB A;  1AJQ A;  1K5Q A;  1GM7 A;  1JVZ A;  2WYD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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