1LWSA

Crystal structure of the intein homing endonuclease pi-scei bound to its recognition sequence
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
454
structure length
427
Chain Sequence
CFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVFEVITFEMGQKKAPDGRIVELVKEVSKSYPISPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAVAKTVNLYSENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
molecule keywords PI-SceI DNA recognition region top strand
total genus 92
structure length 427
sequence length 454
ec nomenclature ec 7.1.2.2: H(+)-transporting two-sector ATPase.
pdb deposition date 2002-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05203 Hom_end_hint Hom_end-associated Hint
A PF05204 Hom_end Homing endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 1lwsA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1lwsA02
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1lwsA03
4E2UA 2CW7A 2IN9A 3IGDA 4UN9A 1DQ3A 4Z1ZA 2VBLA 3HYJA 4YISA 5A78A 4OZ6A 1ZD7A 2QOJZ 4Z1XA 2FLDA 4UNBA 1N3EA 4UN7G 1VDEA 1N3FA 4O1RA 4UN8A 3MX9A 2JMZA 2KEQA 1AM2A 5E63A 3FD2A 2VBLB 3UVFA 4EFJA 4AQUA 2I3QA 1R7MA 2LWYA 1AT0A 1U0DA 1B24A 1P8KZ 4D6OA 1UM2A 3E54A 5AKMA 4UT0A 2IN0A 5E5SA 3MIPA 2VBOA 4KL5A 2XE0A 5A0MA 4O1SA 4GIGA 4AAEA 4D6NA 2IN8A 3EH8A 2L8LA 1MI8A 2VS7A 1T9JA 3C0XA 3NZMA 4E2TA 2VBNA 1AF5A 5AK9A 4AABA 5AKNA 4UN7A 5E5OA 1DFAA 5K08A 5A72A 2O7MA 2VBOB 4AQXA 4YITA 2XE0B 2LQMA 4YHXA 4UNAA 5A0MB 3MXBA 4UN9G 3OORA 2I3PA 3R7PA 1JVAA 4UNCA 2VBJA 4Z20A 3HYIA 1BP7A 3IFJA 2EX5A 2JNQA 2CW8A 5A74A 2VBNB 1T9IA 1EF0A 5A77A 1LWTA 1U0CA 3QQYA 1M5XA 2AB5A 3OOLA 3MXAA 4LQ0A 1ZDEA 1GPPA 5A0WA 3MXBB 4UN8G 4LOXA 3KO2A 5AKFA 3MISA 4AAFA 2IMZA 2VBJB 2DCHX 4KL6A 2VS8A 1G9YA 2LCJA 5I0AA 4AADA 1G9ZA 1MOWA 4AAGA 1LWSA 5E67A 3C0WA
chains in the Genus database with same CATH superfamily
4E2UA 2CW7A 2IN9A 4QFQA 3IGDA 4UN9A 1DQ3A 4Z1ZA 2VBLA 3HYJA 4YISA 5A78A 4OZ6A 1ZD7A 2QOJZ 4Z1XA 2FLDA 4UNBA 1N3EA 4UN7G 1VDEA 1N3FA 4O1RA 4UN8A 3MX9A 2JMZA 4KZSA 2KEQA 1AM2A 5E63A 3FD2A 2VBLB 3UVFA 4EFJA 4AQUA 2I3QA 1R7MA 2LWYA 1AT0A 1U0DA 1B24A 1P8KZ 4D6OA 1UM2A 3E54A 2F4LA 5AKMA 4UT0A 2IN0A 5E5SA 3MIPA 2VBOA 4KL5A 2XE0A 5A0MA 4O1SA 4GIGA 4AAEA 4D6NA 2IN8A 3EH8A 2L8LA 1MI8A 2VS7A 1T9JA 3C0XA 3NZMA 4E2TA 2VBNA 1AF5A 5AK9A 4AABA 5AKNA 4UN7A 5E5OA 1DFAA 5K08A 5A72A 2O7MA 2VBOB 4AQXA 4YITA 2XE0B 2LQMA 4YHXA 4UNAA 5A0MB 3MXBA 4UN9G 3OORA 2I3PA 3R7PA 1JVAA 4UNCA 4LX3A 4Z20A 3HYIA 2VBJA 1BP7A 3IFJA 2EX5A 2JNQA 2CW8A 5A74A 2VBNB 1T9IA 1EF0A 5A77A 1LWTA 1U0CA 3QQYA 1M5XA 2AB5A 3OOLA 3MXAA 4LQ0A 1ZDEA 1GPPA 5A0WA 3MXBB 4UN8G 4LOXA 3KO2A 5AKFA 3MISA 4AAFA 2IMZA 2VBJB 2DCHX 4KL6A 2VS8A 1G9YA 2LCJA 5I0AA 4AADA 1G9ZA 1MOWA 4AAGA 1LWSA 5E67A 3C0WA
chains in the Genus database with same CATH topology
4E2UA 2CW7A 2IN9A 3IGDA 4UN9A 1DQ3A 4Z1ZA 2VBLA 3HYJA 4YISA 5A78A 4OZ6A 1ZD7A 2QOJZ 4Z1XA 2FLDA 4UNBA 1N3EA 4UN7G 1VDEA 1N3FA 4O1RA 4UN8A 3MX9A 2JMZA 2KEQA 1AM2A 5E63A 3FD2A 2VBLB 3UVFA 4EFJA 4AQUA 2I3QA 1R7MA 2LWYA 1AT0A 1U0DA 1B24A 1P8KZ 4D6OA 1UM2A 3E54A 5AKMA 4UT0A 2IN0A 5E5SA 3MIPA 2VBOA 4KL5A 2XE0A 5A0MA 4O1SA 4GIGA 4AAEA 4D6NA 2IN8A 3EH8A 2L8LA 1MI8A 2VS7A 1T9JA 3C0XA 3NZMA 4E2TA 2VBNA 1AF5A 5AK9A 4AABA 5AKNA 4UN7A 5E5OA 1DFAA 5K08A 5A72A 2O7MA 2VBOB 4AQXA 4YITA 2XE0B 2LQMA 4YHXA 4UNAA 5A0MB 3MXBA 4UN9G 3OORA 2I3PA 3R7PA 1JVAA 4UNCA 2VBJA 4Z20A 3HYIA 1BP7A 3IFJA 2EX5A 2JNQA 2CW8A 5A74A 2VBNB 1T9IA 1EF0A 5A77A 1LWTA 1U0CA 3QQYA 1M5XA 2AB5A 3OOLA 3MXAA 4LQ0A 1ZDEA 1GPPA 5A0WA 3MXBB 4UN8G 4LOXA 3KO2A 5AKFA 3MISA 4AAFA 2IMZA 2VBJB 2DCHX 4KL6A 2VS8A 1G9YA 2LCJA 5I0AA 4AADA 1G9ZA 1MOWA 4AAGA 1LWSA 5E67A 3C0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4E2U A;  2CW7 A;  2IN9 A;  3IGD A;  4UN9 A;  1DQ3 A;  4Z1Z A;  2VBL A;  3HYJ A;  4YIS A;  5A78 A;  4OZ6 A;  1ZD7 A;  2QOJ Z;  4Z1X A;  2FLD A;  4UNB A;  1N3E A;  4UN7 G;  1VDE A;  1N3F A;  4O1R A;  4UN8 A;  3MX9 A;  2JMZ A;  2KEQ A;  1AM2 A;  5E63 A;  3FD2 A;  2VBL B;  3UVF A;  4EFJ A;  4AQU A;  2I3Q A;  1R7M A;  2LWY A;  1AT0 A;  1U0D A;  1B24 A;  1P8K Z;  4D6O A;  1UM2 A;  3E54 A;  5AKM A;  4UT0 A;  2IN0 A;  5E5S A;  3MIP A;  2VBO A;  4KL5 A;  2XE0 A;  5A0M A;  4O1S A;  4GIG A;  4AAE A;  4D6N A;  2IN8 A;  3EH8 A;  2L8L A;  1MI8 A;  2VS7 A;  1T9J A;  3C0X A;  3NZM A;  4E2T A;  2VBN A;  1AF5 A;  5AK9 A;  4AAB A;  5AKN A;  4UN7 A;  5E5O A;  1DFA A;  5K08 A;  5A72 A;  2O7M A;  2VBO B;  4AQX A;  4YIT A;  2XE0 B;  2LQM A;  4YHX A;  4UNA A;  5A0M B;  3MXB A;  4UN9 G;  3OOR A;  2I3P A;  3R7P A;  1JVA A;  4UNC A;  2VBJ A;  4Z20 A;  3HYI A;  1BP7 A;  3IFJ A;  2EX5 A;  2JNQ A;  2CW8 A;  5A74 A;  2VBN B;  1T9I A;  1EF0 A;  5A77 A;  1LWT A;  1U0C A;  3QQY A;  1M5X A;  2AB5 A;  3OOL A;  3MXA A;  4LQ0 A;  1ZDE A;  1GPP A;  5A0W A;  3MXB B;  4UN8 G;  4LOX A;  3KO2 A;  5AKF A;  3MIS A;  4AAF A;  2IMZ A;  2VBJ B;  2DCH X;  4KL6 A;  2VS8 A;  1G9Y A;  2LCJ A;  5I0A A;  4AAD A;  1G9Z A;  1MOW A;  4AAG A;  1LWS A;  5E67 A;  3C0W A; 
#chains in the Genus database with same CATH topology
 4E2U A;  2CW7 A;  2IN9 A;  4QFQ A;  3IGD A;  4UN9 A;  1DQ3 A;  4Z1Z A;  2VBL A;  3HYJ A;  4YIS A;  5A78 A;  4OZ6 A;  1ZD7 A;  2QOJ Z;  4Z1X A;  2FLD A;  4UNB A;  1N3E A;  4UN7 G;  1VDE A;  1N3F A;  4O1R A;  4UN8 A;  3MX9 A;  2JMZ A;  4KZS A;  2KEQ A;  1AM2 A;  5E63 A;  3FD2 A;  2VBL B;  3UVF A;  4EFJ A;  4AQU A;  2I3Q A;  1R7M A;  2LWY A;  1AT0 A;  1U0D A;  1B24 A;  1P8K Z;  4D6O A;  1UM2 A;  3E54 A;  2F4L A;  5AKM A;  4UT0 A;  2IN0 A;  5E5S A;  3MIP A;  2VBO A;  4KL5 A;  2XE0 A;  5A0M A;  4O1S A;  4GIG A;  4AAE A;  4D6N A;  2IN8 A;  3EH8 A;  2L8L A;  1MI8 A;  2VS7 A;  1T9J A;  3C0X A;  3NZM A;  4E2T A;  2VBN A;  1AF5 A;  5AK9 A;  4AAB A;  5AKN A;  4UN7 A;  5E5O A;  1DFA A;  5K08 A;  5A72 A;  2O7M A;  2VBO B;  4AQX A;  4YIT A;  2XE0 B;  2LQM A;  4YHX A;  4UNA A;  5A0M B;  3MXB A;  4UN9 G;  3OOR A;  2I3P A;  3R7P A;  1JVA A;  4UNC A;  4LX3 A;  4Z20 A;  3HYI A;  2VBJ A;  1BP7 A;  3IFJ A;  2EX5 A;  2JNQ A;  2CW8 A;  5A74 A;  2VBN B;  1T9I A;  1EF0 A;  5A77 A;  1LWT A;  1U0C A;  3QQY A;  1M5X A;  2AB5 A;  3OOL A;  3MXA A;  4LQ0 A;  1ZDE A;  1GPP A;  5A0W A;  3MXB B;  4UN8 G;  4LOX A;  3KO2 A;  5AKF A;  3MIS A;  4AAF A;  2IMZ A;  2VBJ B;  2DCH X;  4KL6 A;  2VS8 A;  1G9Y A;  2LCJ A;  5I0A A;  4AAD A;  1G9Z A;  1MOW A;  4AAG A;  1LWS A;  5E67 A;  3C0W A; 
#chains in the Genus database with same CATH homology
 4E2U A;  2CW7 A;  2IN9 A;  3IGD A;  4UN9 A;  1DQ3 A;  4Z1Z A;  2VBL A;  3HYJ A;  4YIS A;  5A78 A;  4OZ6 A;  1ZD7 A;  2QOJ Z;  4Z1X A;  2FLD A;  4UNB A;  1N3E A;  4UN7 G;  1VDE A;  1N3F A;  4O1R A;  4UN8 A;  3MX9 A;  2JMZ A;  2KEQ A;  1AM2 A;  5E63 A;  3FD2 A;  2VBL B;  3UVF A;  4EFJ A;  4AQU A;  2I3Q A;  1R7M A;  2LWY A;  1AT0 A;  1U0D A;  1B24 A;  1P8K Z;  4D6O A;  1UM2 A;  3E54 A;  5AKM A;  4UT0 A;  2IN0 A;  5E5S A;  3MIP A;  2VBO A;  4KL5 A;  2XE0 A;  5A0M A;  4O1S A;  4GIG A;  4AAE A;  4D6N A;  2IN8 A;  3EH8 A;  2L8L A;  1MI8 A;  2VS7 A;  1T9J A;  3C0X A;  3NZM A;  4E2T A;  2VBN A;  1AF5 A;  5AK9 A;  4AAB A;  5AKN A;  4UN7 A;  5E5O A;  1DFA A;  5K08 A;  5A72 A;  2O7M A;  2VBO B;  4AQX A;  4YIT A;  2XE0 B;  2LQM A;  4YHX A;  4UNA A;  5A0M B;  3MXB A;  4UN9 G;  3OOR A;  2I3P A;  3R7P A;  1JVA A;  4UNC A;  2VBJ A;  4Z20 A;  3HYI A;  1BP7 A;  3IFJ A;  2EX5 A;  2JNQ A;  2CW8 A;  5A74 A;  2VBN B;  1T9I A;  1EF0 A;  5A77 A;  1LWT A;  1U0C A;  3QQY A;  1M5X A;  2AB5 A;  3OOL A;  3MXA A;  4LQ0 A;  1ZDE A;  1GPP A;  5A0W A;  3MXB B;  4UN8 G;  4LOX A;  3KO2 A;  5AKF A;  3MIS A;  4AAF A;  2IMZ A;  2VBJ B;  2DCH X;  4KL6 A;  2VS8 A;  1G9Y A;  2LCJ A;  5I0A A;  4AAD A;  1G9Z A;  1MOW A;  4AAG A;  1LWS A;  5E67 A;  3C0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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