1LWSA

Crystal structure of the intein homing endonuclease pi-scei bound to its recognition sequence
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
454
structure length
427
Chain Sequence
CFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVFEVITFEMGQKKAPDGRIVELVKEVSKSYPISPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAVAKTVNLYSENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
publication title Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
pubmed doi rcsb
molecule keywords PI-SceI DNA recognition region top strand
total genus 92
structure length 427
sequence length 454
ec nomenclature ec 7.1.2.2: H(+)-transporting two-sector ATPase.
pdb deposition date 2002-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05203 Hom_end_hint Hom_end-associated Hint
A PF05204 Hom_end Homing endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 1lwsA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1lwsA02
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1lwsA03
4UN7G 4YHXA 1AM2A 1AF5A 5A74A 2DCHX 5A0WA 3FD2A 2LQMA 4O1RA 2EX5A 3KO2A 1MI8A 5E67A 3QQYA 3MISA 1N3EA 2JMZA 5A78A 2XE0A 2JNQA 3IFJA 5AKNA 2L8LA 2IN9A 2FLDA 1ZD7A 2KEQA 3HYIA 2IMZA 4D6NA 2VBLB 1VDEA 5A0MB 1GPPA 3OOLA 2VBLA 1P8KZ 4O1SA 4UN8A 3R7PA 3C0XA 4Z20A 5AKMA 1DQ3A 5AK9A 5E5SA 4E2TA 1T9IA 3MX9A 1UM2A 2XE0B 3E54A 1G9YA 1N3FA 4UN7A 4UNAA 4D6OA 5E5OA 2LCJA 3IGDA 4UT0A 2VBOA 2CW8A 1EF0A 3C0WA 4AAGA 4UNCA 2QOJZ 5A77A 2VS8A 1JVAA 2CW7A 1B24A 3HYJA 4AQUA 3NZMA 1ZDEA 4AAEA 2VS7A 3MXAA 3OORA 4OZ6A 4Z1ZA 2VBJA 4AAFA 4EFJA 4YISA 4UN9G 5E63A 1LWSA 1R7MA 2VBOB 3MXBB 2I3QA 2VBNB 4UN9A 3MXBA 2IN0A 1MOWA 2VBNA 1T9JA 1M5XA 3UVFA 2AB5A 2O7MA 4LQ0A 2IN8A 1LWTA 4YITA 2VBJB 4GIGA 5I0AA 4KL6A 4Z1XA 4KL5A 1BP7A 5A72A 1G9ZA 4AADA 4UN8G 3EH8A 2LWYA 2I3PA 4E2UA 4AQXA 4AABA 5K08A 1AT0A 4UNBA 5A0MA 4LOXA 1U0DA 1DFAA 1U0CA 3MIPA 5AKFA
chains in the Genus database with same CATH superfamily
4UN7G 4YHXA 1AM2A 1AF5A 5A74A 2DCHX 5A0WA 3FD2A 2LQMA 4O1RA 2EX5A 3KO2A 1MI8A 5E67A 3QQYA 3MISA 1N3EA 2JMZA 5A78A 2XE0A 2JNQA 3IFJA 5AKNA 2L8LA 2IN9A 2FLDA 1ZD7A 2KEQA 3HYIA 2IMZA 4D6NA 2VBLB 1VDEA 5A0MB 1GPPA 3OOLA 2VBLA 1P8KZ 4O1SA 4UN8A 3R7PA 3C0XA 4Z20A 5AKMA 1DQ3A 5AK9A 5E5SA 4KZSA 4E2TA 1T9IA 3MX9A 1UM2A 2XE0B 3E54A 1G9YA 1N3FA 4UN7A 4UNAA 4D6OA 5E5OA 4QFQA 2LCJA 3IGDA 4UT0A 2VBOA 2CW8A 1EF0A 3C0WA 4AAGA 2F4LA 4UNCA 2QOJZ 5A77A 2VS8A 1JVAA 2CW7A 1B24A 3HYJA 4AQUA 3NZMA 1ZDEA 4AAEA 2VS7A 3MXAA 3OORA 4OZ6A 4Z1ZA 2VBJA 4AAFA 4EFJA 4YISA 4UN9G 5E63A 1LWSA 1R7MA 2VBOB 3MXBB 2I3QA 2VBNB 4UN9A 3MXBA 2IN0A 1MOWA 2VBNA 1T9JA 1M5XA 3UVFA 2AB5A 2O7MA 4LQ0A 2IN8A 1LWTA 4YITA 2VBJB 4GIGA 5I0AA 4KL6A 4Z1XA 4KL5A 1BP7A 5A72A 1G9ZA 4AADA 4UN8G 3EH8A 2LWYA 2I3PA 4E2UA 4AQXA 4AABA 5K08A 1AT0A 4UNBA 5A0MA 4LOXA 4LX3A 1U0DA 1DFAA 1U0CA 3MIPA 5AKFA
chains in the Genus database with same CATH topology
4UN7G 4YHXA 1AM2A 1AF5A 5A74A 2DCHX 5A0WA 3FD2A 2LQMA 4O1RA 2EX5A 3KO2A 1MI8A 5E67A 3QQYA 3MISA 1N3EA 2JMZA 5A78A 2XE0A 2JNQA 3IFJA 5AKNA 2L8LA 2IN9A 2FLDA 1ZD7A 2KEQA 3HYIA 2IMZA 4D6NA 2VBLB 1VDEA 5A0MB 1GPPA 3OOLA 2VBLA 1P8KZ 4O1SA 4UN8A 3R7PA 3C0XA 4Z20A 5AKMA 1DQ3A 5AK9A 5E5SA 4E2TA 1T9IA 3MX9A 1UM2A 2XE0B 3E54A 1G9YA 1N3FA 4UN7A 4UNAA 4D6OA 5E5OA 2LCJA 3IGDA 4UT0A 2VBOA 2CW8A 1EF0A 3C0WA 4AAGA 4UNCA 2QOJZ 5A77A 2VS8A 1JVAA 2CW7A 1B24A 3HYJA 4AQUA 3NZMA 1ZDEA 4AAEA 2VS7A 3MXAA 3OORA 4OZ6A 4Z1ZA 2VBJA 4AAFA 4EFJA 4YISA 4UN9G 5E63A 1LWSA 1R7MA 2VBOB 3MXBB 2I3QA 2VBNB 4UN9A 3MXBA 2IN0A 1MOWA 2VBNA 1T9JA 1M5XA 3UVFA 2AB5A 2O7MA 4LQ0A 2IN8A 1LWTA 4YITA 2VBJB 4GIGA 5I0AA 4KL6A 4Z1XA 4KL5A 1BP7A 5A72A 1G9ZA 4AADA 4UN8G 3EH8A 2LWYA 2I3PA 4E2UA 4AQXA 4AABA 5K08A 1AT0A 4UNBA 5A0MA 4LOXA 1U0DA 1DFAA 1U0CA 3MIPA 5AKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UN7 G;  4YHX A;  1AM2 A;  1AF5 A;  5A74 A;  2DCH X;  5A0W A;  3FD2 A;  2LQM A;  4O1R A;  2EX5 A;  3KO2 A;  1MI8 A;  5E67 A;  3QQY A;  3MIS A;  1N3E A;  2JMZ A;  5A78 A;  2XE0 A;  2JNQ A;  3IFJ A;  5AKN A;  2L8L A;  2IN9 A;  2FLD A;  1ZD7 A;  2KEQ A;  3HYI A;  2IMZ A;  4D6N A;  2VBL B;  1VDE A;  5A0M B;  1GPP A;  3OOL A;  2VBL A;  1P8K Z;  4O1S A;  4UN8 A;  3R7P A;  3C0X A;  4Z20 A;  5AKM A;  1DQ3 A;  5AK9 A;  5E5S A;  4E2T A;  1T9I A;  3MX9 A;  1UM2 A;  2XE0 B;  3E54 A;  1G9Y A;  1N3F A;  4UN7 A;  4UNA A;  4D6O A;  5E5O A;  2LCJ A;  3IGD A;  4UT0 A;  2VBO A;  2CW8 A;  1EF0 A;  3C0W A;  4AAG A;  4UNC A;  2QOJ Z;  5A77 A;  2VS8 A;  1JVA A;  2CW7 A;  1B24 A;  3HYJ A;  4AQU A;  3NZM A;  1ZDE A;  4AAE A;  2VS7 A;  3MXA A;  3OOR A;  4OZ6 A;  4Z1Z A;  2VBJ A;  4AAF A;  4EFJ A;  4YIS A;  4UN9 G;  5E63 A;  1LWS A;  1R7M A;  2VBO B;  3MXB B;  2I3Q A;  2VBN B;  4UN9 A;  3MXB A;  2IN0 A;  1MOW A;  2VBN A;  1T9J A;  1M5X A;  3UVF A;  2AB5 A;  2O7M A;  4LQ0 A;  2IN8 A;  1LWT A;  4YIT A;  2VBJ B;  4GIG A;  5I0A A;  4KL6 A;  4Z1X A;  4KL5 A;  1BP7 A;  5A72 A;  1G9Z A;  4AAD A;  4UN8 G;  3EH8 A;  2LWY A;  2I3P A;  4E2U A;  4AQX A;  4AAB A;  5K08 A;  1AT0 A;  4UNB A;  5A0M A;  4LOX A;  1U0D A;  1DFA A;  1U0C A;  3MIP A;  5AKF A; 
#chains in the Genus database with same CATH topology
 4UN7 G;  4YHX A;  1AM2 A;  1AF5 A;  5A74 A;  2DCH X;  5A0W A;  3FD2 A;  2LQM A;  4O1R A;  2EX5 A;  3KO2 A;  1MI8 A;  5E67 A;  3QQY A;  3MIS A;  1N3E A;  2JMZ A;  5A78 A;  2XE0 A;  2JNQ A;  3IFJ A;  5AKN A;  2L8L A;  2IN9 A;  2FLD A;  1ZD7 A;  2KEQ A;  3HYI A;  2IMZ A;  4D6N A;  2VBL B;  1VDE A;  5A0M B;  1GPP A;  3OOL A;  2VBL A;  1P8K Z;  4O1S A;  4UN8 A;  3R7P A;  3C0X A;  4Z20 A;  5AKM A;  1DQ3 A;  5AK9 A;  5E5S A;  4KZS A;  4E2T A;  1T9I A;  3MX9 A;  1UM2 A;  2XE0 B;  3E54 A;  1G9Y A;  1N3F A;  4UN7 A;  4UNA A;  4D6O A;  5E5O A;  4QFQ A;  2LCJ A;  3IGD A;  4UT0 A;  2VBO A;  2CW8 A;  1EF0 A;  3C0W A;  4AAG A;  2F4L A;  4UNC A;  2QOJ Z;  5A77 A;  2VS8 A;  1JVA A;  2CW7 A;  1B24 A;  3HYJ A;  4AQU A;  3NZM A;  1ZDE A;  4AAE A;  2VS7 A;  3MXA A;  3OOR A;  4OZ6 A;  4Z1Z A;  2VBJ A;  4AAF A;  4EFJ A;  4YIS A;  4UN9 G;  5E63 A;  1LWS A;  1R7M A;  2VBO B;  3MXB B;  2I3Q A;  2VBN B;  4UN9 A;  3MXB A;  2IN0 A;  1MOW A;  2VBN A;  1T9J A;  1M5X A;  3UVF A;  2AB5 A;  2O7M A;  4LQ0 A;  2IN8 A;  1LWT A;  4YIT A;  2VBJ B;  4GIG A;  5I0A A;  4KL6 A;  4Z1X A;  4KL5 A;  1BP7 A;  5A72 A;  1G9Z A;  4AAD A;  4UN8 G;  3EH8 A;  2LWY A;  2I3P A;  4E2U A;  4AQX A;  4AAB A;  5K08 A;  1AT0 A;  4UNB A;  5A0M A;  4LOX A;  4LX3 A;  1U0D A;  1DFA A;  1U0C A;  3MIP A;  5AKF A; 
#chains in the Genus database with same CATH homology
 4UN7 G;  4YHX A;  1AM2 A;  1AF5 A;  5A74 A;  2DCH X;  5A0W A;  3FD2 A;  2LQM A;  4O1R A;  2EX5 A;  3KO2 A;  1MI8 A;  5E67 A;  3QQY A;  3MIS A;  1N3E A;  2JMZ A;  5A78 A;  2XE0 A;  2JNQ A;  3IFJ A;  5AKN A;  2L8L A;  2IN9 A;  2FLD A;  1ZD7 A;  2KEQ A;  3HYI A;  2IMZ A;  4D6N A;  2VBL B;  1VDE A;  5A0M B;  1GPP A;  3OOL A;  2VBL A;  1P8K Z;  4O1S A;  4UN8 A;  3R7P A;  3C0X A;  4Z20 A;  5AKM A;  1DQ3 A;  5AK9 A;  5E5S A;  4E2T A;  1T9I A;  3MX9 A;  1UM2 A;  2XE0 B;  3E54 A;  1G9Y A;  1N3F A;  4UN7 A;  4UNA A;  4D6O A;  5E5O A;  2LCJ A;  3IGD A;  4UT0 A;  2VBO A;  2CW8 A;  1EF0 A;  3C0W A;  4AAG A;  4UNC A;  2QOJ Z;  5A77 A;  2VS8 A;  1JVA A;  2CW7 A;  1B24 A;  3HYJ A;  4AQU A;  3NZM A;  1ZDE A;  4AAE A;  2VS7 A;  3MXA A;  3OOR A;  4OZ6 A;  4Z1Z A;  2VBJ A;  4AAF A;  4EFJ A;  4YIS A;  4UN9 G;  5E63 A;  1LWS A;  1R7M A;  2VBO B;  3MXB B;  2I3Q A;  2VBN B;  4UN9 A;  3MXB A;  2IN0 A;  1MOW A;  2VBN A;  1T9J A;  1M5X A;  3UVF A;  2AB5 A;  2O7M A;  4LQ0 A;  2IN8 A;  1LWT A;  4YIT A;  2VBJ B;  4GIG A;  5I0A A;  4KL6 A;  4Z1X A;  4KL5 A;  1BP7 A;  5A72 A;  1G9Z A;  4AAD A;  4UN8 G;  3EH8 A;  2LWY A;  2I3P A;  4E2U A;  4AQX A;  4AAB A;  5K08 A;  1AT0 A;  4UNB A;  5A0M A;  4LOX A;  1U0D A;  1DFA A;  1U0C A;  3MIP A;  5AKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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