1LWSA

Crystal structure of the intein homing endonuclease pi-scei bound to its recognition sequence
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
454
structure length
427
Chain Sequence
CFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAHKSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVFEVITFEMGQKKAPDGRIVELVKEVSKSYPISPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHFFDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAVAKTVNLYSENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFLAGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIYMSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQVVVHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
molecule keywords PI-SceI DNA recognition region top strand
total genus 92
structure length 427
sequence length 454
ec nomenclature ec 7.1.2.2: H(+)-transporting two-sector ATPase.
pdb deposition date 2002-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF05203 Hom_end_hint Hom_end-associated Hint
A PF05204 Hom_end Homing endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.16.10 Mainly Beta Beta Complex Endonuclease - Pi-scei; Chain A, domain 1 Hedgehog/Intein (Hint) domain 1lwsA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1lwsA02
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1lwsA03
2IMZA 2VBOA 2LCJA 4KL6A 4LQ0A 4AABA 2QOJZ 5AK9A 1M5XA 1EF0A 2VBLB 4GIGA 2O7MA 3IFJA 3KO2A 3R7PA 4D6NA 3HYIA 1VDEA 3OORA 3UVFA 4AAFA 1ZD7A 2IN9A 2VBJA 1U0DA 2CW7A 2L8LA 2VBNB 3MIPA 1R7MA 2FLDA 5AKMA 2KEQA 1AT0A 5E5SA 1P8KZ 2JNQA 4KL5A 4Z1XA 2DCHX 4AQUA 1T9IA 5E63A 2VBLA 3MXBB 3FD2A 2VS7A 2LQMA 4OZ6A 2IN0A 5K08A 5A74A 4UNBA 4O1SA 5E5OA 4UNCA 5A0MB 2JMZA 1LWTA 4EFJA 1G9ZA 5A77A 1N3EA 3QQYA 4UN8A 2VBOB 1G9YA 3MISA 4UN9A 1BP7A 5A0WA 1AM2A 4UN9G 5I0AA 4AQXA 4O1RA 3MXBA 1JVAA 5AKFA 3HYJA 1DFAA 4YITA 2VBJB 2I3QA 2LWYA 3C0XA 5A0MA 4LOXA 2IN8A 2XE0B 1B24A 3NZMA 4YISA 4Z1ZA 2VBNA 1N3FA 4YHXA 3IGDA 4UT0A 1T9JA 1GPPA 4AAGA 4AAEA 1UM2A 5AKNA 4UN8G 1U0CA 4UN7A 2CW8A 3EH8A 2EX5A 1AF5A 4UN7G 2AB5A 4Z20A 4D6OA 4AADA 3E54A 5E67A 5A78A 3MX9A 3C0WA 1MOWA 1DQ3A 4E2TA 5A72A 4UNAA 3MXAA 4E2UA 1LWSA 3OOLA 2XE0A 2VS8A 1ZDEA 1MI8A 2I3PA
chains in the Genus database with same CATH superfamily
2IMZA 2VBOA 2LCJA 4KL6A 4LQ0A 4AABA 2QOJZ 5AK9A 1M5XA 1EF0A 2VBLB 4GIGA 2O7MA 3IFJA 3KO2A 3R7PA 4D6NA 3HYIA 1VDEA 3OORA 3UVFA 4AAFA 1ZD7A 4KZSA 2IN9A 2VBJA 1U0DA 2CW7A 2L8LA 2VBNB 3MIPA 1R7MA 2FLDA 5AKMA 2KEQA 1AT0A 5E5SA 1P8KZ 2JNQA 4KL5A 4Z1XA 2DCHX 4AQUA 1T9IA 5E63A 2VBLA 3MXBB 3FD2A 2VS7A 2LQMA 4OZ6A 2IN0A 5K08A 5A74A 4UNBA 4O1SA 5E5OA 4UNCA 5A0MB 2JMZA 1LWTA 4EFJA 1G9ZA 5A77A 1N3EA 3QQYA 4UN8A 2VBOB 1G9YA 3MISA 4UN9A 1BP7A 2F4LA 5A0WA 1AM2A 4UN9G 5I0AA 4LX3A 4AQXA 4O1RA 3MXBA 1JVAA 5AKFA 3HYJA 1DFAA 4YITA 2VBJB 2I3QA 2LWYA 3C0XA 5A0MA 4LOXA 2IN8A 2XE0B 1B24A 3NZMA 4YISA 4Z1ZA 2VBNA 1N3FA 4YHXA 3IGDA 4UT0A 1T9JA 1GPPA 4AAGA 4AAEA 1UM2A 5AKNA 4UN8G 1U0CA 4UN7A 2CW8A 3EH8A 2EX5A 1AF5A 4UN7G 2AB5A 4Z20A 4D6OA 4AADA 3E54A 5E67A 5A78A 3MX9A 3C0WA 1MOWA 1DQ3A 4E2TA 5A72A 4UNAA 3MXAA 4E2UA 1LWSA 3OOLA 2XE0A 2VS8A 1ZDEA 4QFQA 1MI8A 2I3PA
chains in the Genus database with same CATH topology
2IMZA 2VBOA 2LCJA 4KL6A 4LQ0A 4AABA 2QOJZ 5AK9A 1M5XA 1EF0A 2VBLB 4GIGA 2O7MA 3IFJA 3KO2A 3R7PA 4D6NA 3HYIA 1VDEA 3OORA 3UVFA 4AAFA 1ZD7A 2IN9A 2VBJA 1U0DA 2CW7A 2L8LA 2VBNB 3MIPA 1R7MA 2FLDA 5AKMA 2KEQA 1AT0A 5E5SA 1P8KZ 2JNQA 4KL5A 4Z1XA 2DCHX 4AQUA 1T9IA 5E63A 2VBLA 3MXBB 3FD2A 2VS7A 2LQMA 4OZ6A 2IN0A 5K08A 5A74A 4UNBA 4O1SA 5E5OA 4UNCA 5A0MB 2JMZA 1LWTA 4EFJA 1G9ZA 5A77A 1N3EA 3QQYA 4UN8A 2VBOB 1G9YA 3MISA 4UN9A 1BP7A 5A0WA 1AM2A 4UN9G 5I0AA 4AQXA 4O1RA 3MXBA 1JVAA 5AKFA 3HYJA 1DFAA 4YITA 2VBJB 2I3QA 2LWYA 3C0XA 5A0MA 4LOXA 2IN8A 2XE0B 1B24A 3NZMA 4YISA 4Z1ZA 2VBNA 1N3FA 4YHXA 3IGDA 4UT0A 1T9JA 1GPPA 4AAGA 4AAEA 1UM2A 5AKNA 4UN8G 1U0CA 4UN7A 2CW8A 3EH8A 2EX5A 1AF5A 4UN7G 2AB5A 4Z20A 4D6OA 4AADA 3E54A 5E67A 5A78A 3MX9A 3C0WA 1MOWA 1DQ3A 4E2TA 5A72A 4UNAA 3MXAA 4E2UA 1LWSA 3OOLA 2XE0A 2VS8A 1ZDEA 1MI8A 2I3PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IMZ A;  2VBO A;  2LCJ A;  4KL6 A;  4LQ0 A;  4AAB A;  2QOJ Z;  5AK9 A;  1M5X A;  1EF0 A;  2VBL B;  4GIG A;  2O7M A;  3IFJ A;  3KO2 A;  3R7P A;  4D6N A;  3HYI A;  1VDE A;  3OOR A;  3UVF A;  4AAF A;  1ZD7 A;  2IN9 A;  2VBJ A;  1U0D A;  2CW7 A;  2L8L A;  2VBN B;  3MIP A;  1R7M A;  2FLD A;  5AKM A;  2KEQ A;  1AT0 A;  5E5S A;  1P8K Z;  2JNQ A;  4KL5 A;  4Z1X A;  2DCH X;  4AQU A;  1T9I A;  5E63 A;  2VBL A;  3MXB B;  3FD2 A;  2VS7 A;  2LQM A;  4OZ6 A;  2IN0 A;  5K08 A;  5A74 A;  4UNB A;  4O1S A;  5E5O A;  4UNC A;  5A0M B;  2JMZ A;  1LWT A;  4EFJ A;  1G9Z A;  5A77 A;  1N3E A;  3QQY A;  4UN8 A;  2VBO B;  1G9Y A;  3MIS A;  4UN9 A;  1BP7 A;  5A0W A;  1AM2 A;  4UN9 G;  5I0A A;  4AQX A;  4O1R A;  3MXB A;  1JVA A;  5AKF A;  3HYJ A;  1DFA A;  4YIT A;  2VBJ B;  2I3Q A;  2LWY A;  3C0X A;  5A0M A;  4LOX A;  2IN8 A;  2XE0 B;  1B24 A;  3NZM A;  4YIS A;  4Z1Z A;  2VBN A;  1N3F A;  4YHX A;  3IGD A;  4UT0 A;  1T9J A;  1GPP A;  4AAG A;  4AAE A;  1UM2 A;  5AKN A;  4UN8 G;  1U0C A;  4UN7 A;  2CW8 A;  3EH8 A;  2EX5 A;  1AF5 A;  4UN7 G;  2AB5 A;  4Z20 A;  4D6O A;  4AAD A;  3E54 A;  5E67 A;  5A78 A;  3MX9 A;  3C0W A;  1MOW A;  1DQ3 A;  4E2T A;  5A72 A;  4UNA A;  3MXA A;  4E2U A;  1LWS A;  3OOL A;  2XE0 A;  2VS8 A;  1ZDE A;  1MI8 A;  2I3P A; 
#chains in the Genus database with same CATH topology
 2IMZ A;  2VBO A;  2LCJ A;  4KL6 A;  4LQ0 A;  4AAB A;  2QOJ Z;  5AK9 A;  1M5X A;  1EF0 A;  2VBL B;  4GIG A;  2O7M A;  3IFJ A;  3KO2 A;  3R7P A;  4D6N A;  3HYI A;  1VDE A;  3OOR A;  3UVF A;  4AAF A;  1ZD7 A;  4KZS A;  2IN9 A;  2VBJ A;  1U0D A;  2CW7 A;  2L8L A;  2VBN B;  3MIP A;  1R7M A;  2FLD A;  5AKM A;  2KEQ A;  1AT0 A;  5E5S A;  1P8K Z;  2JNQ A;  4KL5 A;  4Z1X A;  2DCH X;  4AQU A;  1T9I A;  5E63 A;  2VBL A;  3MXB B;  3FD2 A;  2VS7 A;  2LQM A;  4OZ6 A;  2IN0 A;  5K08 A;  5A74 A;  4UNB A;  4O1S A;  5E5O A;  4UNC A;  5A0M B;  2JMZ A;  1LWT A;  4EFJ A;  1G9Z A;  5A77 A;  1N3E A;  3QQY A;  4UN8 A;  2VBO B;  1G9Y A;  3MIS A;  4UN9 A;  1BP7 A;  2F4L A;  5A0W A;  1AM2 A;  4UN9 G;  5I0A A;  4LX3 A;  4AQX A;  4O1R A;  3MXB A;  1JVA A;  5AKF A;  3HYJ A;  1DFA A;  4YIT A;  2VBJ B;  2I3Q A;  2LWY A;  3C0X A;  5A0M A;  4LOX A;  2IN8 A;  2XE0 B;  1B24 A;  3NZM A;  4YIS A;  4Z1Z A;  2VBN A;  1N3F A;  4YHX A;  3IGD A;  4UT0 A;  1T9J A;  1GPP A;  4AAG A;  4AAE A;  1UM2 A;  5AKN A;  4UN8 G;  1U0C A;  4UN7 A;  2CW8 A;  3EH8 A;  2EX5 A;  1AF5 A;  4UN7 G;  2AB5 A;  4Z20 A;  4D6O A;  4AAD A;  3E54 A;  5E67 A;  5A78 A;  3MX9 A;  3C0W A;  1MOW A;  1DQ3 A;  4E2T A;  5A72 A;  4UNA A;  3MXA A;  4E2U A;  1LWS A;  3OOL A;  2XE0 A;  2VS8 A;  1ZDE A;  4QFQ A;  1MI8 A;  2I3P A; 
#chains in the Genus database with same CATH homology
 2IMZ A;  2VBO A;  2LCJ A;  4KL6 A;  4LQ0 A;  4AAB A;  2QOJ Z;  5AK9 A;  1M5X A;  1EF0 A;  2VBL B;  4GIG A;  2O7M A;  3IFJ A;  3KO2 A;  3R7P A;  4D6N A;  3HYI A;  1VDE A;  3OOR A;  3UVF A;  4AAF A;  1ZD7 A;  2IN9 A;  2VBJ A;  1U0D A;  2CW7 A;  2L8L A;  2VBN B;  3MIP A;  1R7M A;  2FLD A;  5AKM A;  2KEQ A;  1AT0 A;  5E5S A;  1P8K Z;  2JNQ A;  4KL5 A;  4Z1X A;  2DCH X;  4AQU A;  1T9I A;  5E63 A;  2VBL A;  3MXB B;  3FD2 A;  2VS7 A;  2LQM A;  4OZ6 A;  2IN0 A;  5K08 A;  5A74 A;  4UNB A;  4O1S A;  5E5O A;  4UNC A;  5A0M B;  2JMZ A;  1LWT A;  4EFJ A;  1G9Z A;  5A77 A;  1N3E A;  3QQY A;  4UN8 A;  2VBO B;  1G9Y A;  3MIS A;  4UN9 A;  1BP7 A;  5A0W A;  1AM2 A;  4UN9 G;  5I0A A;  4AQX A;  4O1R A;  3MXB A;  1JVA A;  5AKF A;  3HYJ A;  1DFA A;  4YIT A;  2VBJ B;  2I3Q A;  2LWY A;  3C0X A;  5A0M A;  4LOX A;  2IN8 A;  2XE0 B;  1B24 A;  3NZM A;  4YIS A;  4Z1Z A;  2VBN A;  1N3F A;  4YHX A;  3IGD A;  4UT0 A;  1T9J A;  1GPP A;  4AAG A;  4AAE A;  1UM2 A;  5AKN A;  4UN8 G;  1U0C A;  4UN7 A;  2CW8 A;  3EH8 A;  2EX5 A;  1AF5 A;  4UN7 G;  2AB5 A;  4Z20 A;  4D6O A;  4AAD A;  3E54 A;  5E67 A;  5A78 A;  3MX9 A;  3C0W A;  1MOW A;  1DQ3 A;  4E2T A;  5A72 A;  4UNA A;  3MXA A;  4E2U A;  1LWS A;  3OOL A;  2XE0 A;  2VS8 A;  1ZDE A;  1MI8 A;  2I3P A; 
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similar chains in the Genus database (?% sequence similarity)
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