2AE3 | Genus

Total Genus 51

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	51
sequence length	159
structure length	159
Chain Sequence	QAPIAAYKPRSNEILWDGYGVPHIYGVDAPSAFYGYGWAQARSHGDNILRLYGEARGKGAEYWGPDYEQTTVWLLTNGVPERAQQWYAQQSPDFRANLDAFAAGINAYAQQNPDDISPDVRQVLPVSGADVVAHAHRLMNFLYVASPGRTLGEGDPPDL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Pseudomonas sp.
publication title	Insight into autoproteolytic activation from the structure of cephalosporin acylase: a protein with two proteolytic chemistries. pubmed doi rcsb
molecule keywords	Glutaryl 7-Aminocephalosporanic Acid Acylase
total genus	51
structure length	159
sequence length	159
ec nomenclature	ec 3.5.1.93: Glutaryl-7-aminocephalosporanic-acid acylase.
pdb deposition date	2005-07-21

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.439.10	Mainly Alpha	Orthogonal Bundle	Penicillin Amidohydrolase; domain 1	Penicillin Amidohydrolase, domain 1	2ae3A00

1K7DA 3SRAA 1PNKA 2WYEA 4M1JA 1GK0A 3L91A 4PELA 4YFBA 1FXHA 3SRCA 3SRBA 4HSRA 4WKUA 1GM8A 1AI6A 1KECA 2AE3A 4E57A 3ML0A 4BTHA 1AI5A 1AI4A 1AJNA 1AJQA 4HSTA 4E56A 1H2GA 1JW0A 1PNLA 4K2GA 1GK1A 1JX9A 4E55A 1K5SA 4WKSA 2AE4A 3JTRA 1GK9A 1OR0A 1GKFA 1GM9A 1PNMA 4WKTA 1FM2A 1GHDA 2WYDA 4PEMA 4YF9A 1FXVA 3JTQA 2AE5A 2ADVA 1KEHA 4WKVA 1E3AA 4YFAA 2WYBA 3K3WA 1K5QA 3L94A 3S8RA 1GM7A 1AI7A 1JVZA 1AJPA 2WYCA 4K2FA 1CP9A
chains in the Genus database with same CATH superfamily

1K7DA 3SRAA 1PNKA 2WYEA 4M1JA 1GK0A 3L91A 4PELA 4YFBA 1FXHA 3SRCA 3SRBA 4HSRA 4WKUA 1GM8A 1AI6A 1KECA 2AE3A 4E57A 3ML0A 4BTHA 4BWCA 1AI5A 1AI4A 1AJNA 1AJQA 4HSTA 4E56A 1H2GA 1JW0A 1PNLA 4K2GA 1GK1A 1JX9A 4E55A 1K5SA 4WKSA 2AE4A 3JTRA 1GK9A 1OR0A 1GKFA 1GM9A 1PNMA 4WKTA 1FM2A 1GHDA 2WYDA 4PEMA 4YF9A 1FXVA 3JTQA 2AE5A 2ADVA 1KEHA 4WKVA 1E3AA 3FGRA 4YFAA 2WYBA 3K3WA 1K5QA 3L94A 3S8RA 1GM7A 1AI7A 1JVZA 3FGTA 1AJPA 2WYCA 4K2FA 1CP9A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1K7D A;  3SRA A;  1PNK A;  2WYE A;  4M1J A;  1GK0 A;  3L91 A;  4PEL A;  4YFB A;  1FXH A;  3SRC A;  3SRB A;  4HSR A;  4WKU A;  1GM8 A;  1AI6 A;  1KEC A;  2AE3 A;  4E57 A;  3ML0 A;  4BTH A;  1AI5 A;  1AI4 A;  1AJN A;  1AJQ A;  4HST A;  4E56 A;  1H2G A;  1JW0 A;  1PNL A;  4K2G A;  1GK1 A;  1JX9 A;  4E55 A;  1K5S A;  4WKS A;  2AE4 A;  3JTR A;  1GK9 A;  1OR0 A;  1GKF A;  1GM9 A;  1PNM A;  4WKT A;  1FM2 A;  1GHD A;  2WYD A;  4PEM A;  4YF9 A;  1FXV A;  3JTQ A;  2AE5 A;  2ADV A;  1KEH A;  4WKV A;  1E3A A;  4YFA A;  2WYB A;  3K3W A;  1K5Q A;  3L94 A;  3S8R A;  1GM7 A;  1AI7 A;  1JVZ A;  1AJP A;  2WYC A;  4K2F A;  1CP9 A; 
#chains in the Genus database with same CATH topology
 1K7D A;  3SRA A;  1PNK A;  2WYE A;  4M1J A;  1GK0 A;  3L91 A;  4PEL A;  4YFB A;  1FXH A;  3SRC A;  3SRB A;  4HSR A;  4WKU A;  1GM8 A;  1AI6 A;  1KEC A;  2AE3 A;  4E57 A;  3ML0 A;  4BTH A;  4BWC A;  1AI5 A;  1AI4 A;  1AJN A;  1AJQ A;  4HST A;  4E56 A;  1H2G A;  1JW0 A;  1PNL A;  4K2G A;  1GK1 A;  1JX9 A;  4E55 A;  1K5S A;  4WKS A;  2AE4 A;  3JTR A;  1GK9 A;  1OR0 A;  1GKF A;  1GM9 A;  1PNM A;  4WKT A;  1FM2 A;  1GHD A;  2WYD A;  4PEM A;  4YF9 A;  1FXV A;  3JTQ A;  2AE5 A;  2ADV A;  1KEH A;  4WKV A;  1E3A A;  3FGR A;  4YFA A;  2WYB A;  3K3W A;  1K5Q A;  3L94 A;  3S8R A;  1GM7 A;  1AI7 A;  1JVZ A;  3FGT A;  1AJP A;  2WYC A;  4K2F A;  1CP9 A; 
#chains in the Genus database with same CATH homology
 1K7D A;  3SRA A;  1PNK A;  2WYE A;  4M1J A;  1GK0 A;  3L91 A;  4PEL A;  4YFB A;  1FXH A;  3SRC A;  3SRB A;  4HSR A;  4WKU A;  1GM8 A;  1AI6 A;  1KEC A;  2AE3 A;  4E57 A;  3ML0 A;  4BTH A;  1AI5 A;  1AI4 A;  1AJN A;  1AJQ A;  4HST A;  4E56 A;  1H2G A;  1JW0 A;  1PNL A;  4K2G A;  1GK1 A;  1JX9 A;  4E55 A;  1K5S A;  4WKS A;  2AE4 A;  3JTR A;  1GK9 A;  1OR0 A;  1GKF A;  1GM9 A;  1PNM A;  4WKT A;  1FM2 A;  1GHD A;  2WYD A;  4PEM A;  4YF9 A;  1FXV A;  3JTQ A;  2AE5 A;  2ADV A;  1KEH A;  4WKV A;  1E3A A;  4YFA A;  2WYB A;  3K3W A;  1K5Q A;  3L94 A;  3S8R A;  1GM7 A;  1AI7 A;  1JVZ A;  1AJP A;  2WYC A;  4K2F A;  1CP9 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2AE3A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

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