2QFQA

E. coli epsp synthase pro101leu liganded with s3p
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
427
structure length
427
Chain Sequence
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRLLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of glyphosate tolerance resulting from mutations of Pro101 in Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords 3-phosphoshikimate 1-carboxyvinyltransferase
total genus 158
structure length 427
sequence length 427
ec nomenclature ec 2.5.1.19: 3-phosphoshikimate 1-carboxyvinyltransferase.
pdb deposition date 2007-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00275 EPSP_synthase EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 2qfqA02
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 2qfqA01
1RF4A 3R38A 3LTHA 3ZH3A 3SWEA 1Q36A 3SWQA 2Z2CA 3ISSA 2O0EA 1EYNA 3V5VA 4E7GA 2RL2A 3SPBA 4EGRA 2O0BA 1UAEA 2O0XA 3SU9A 2YVWA 5BQ2A 4N3PA 1P88A 3KQAA 2GG6A 3FJXA 3FK0A 2QFSA 1G6TA 3ROIA 3SWIA 2PQ9A 2GGDA 2BJBA 3SWAA 2O0ZA 3SWDA 5U4HA 1Q3GA 5BS5A 4E7FA 3SG1A 4EIIA 2O0DA 2GG4A 3TI2A 4ZNDA 5BUFA 4E7EA 4R7UA 1G6SA 3TR1A 3FJZA 2O15A 1X8RA 3VCYA 4GFPA 1P89A 2AAYA 2QFQA 2PQDA 2QFUA 1NAWA 3ZH4A 1EJCA 1RF5A 1DLGA 3KQJA 4E7CA 1X8TA 2GGAA 1RYWA 3SWGA 4FQDA 3KR6A 3UPKA 2QFTA 3FK1A 1MI4A 2AA9A 2PQBA 3SLHA 1YBGA 1RF6A 2PQCA 1A2NA 3NVSA 3V4TA 4E7DA 3RMTA 4E7BA 2RL1A 1EJDA
chains in the Genus database with same CATH superfamily
4O89A 1RF4A 3R38A 3LTHA 3ZH3A 3SWEA 1Q36A 3SWQA 2Z2CA 3ISSA 2O0EA 1EYNA 3V5VA 4E7GA 2RL2A 3TUXA 3SPBA 4EGRA 2O0BA 1UAEA 2O0XA 3TW3A 3SU9A 2YVWA 5BQ2A 4N3PA 1P88A 3KQAA 2GG6A 3FJXA 3FK0A 2QFSA 1G6TA 3ROIA 3SWIA 2PQ9A 2GGDA 2BJBA 3SWAA 2O0ZA 3SWDA 5U4HA 1Q3GA 1QMHA 5BS5A 4E7FA 3SG1A 4EIIA 2O0DA 2GG4A 3TI2A 4ZNDA 5BUFA 4E7EA 4R7UA 3PQVA 1G6SA 3TR1A 3FJZA 2O15A 1X8RA 3VCYA 4GFPA 1P89A 2AAYA 2QFQA 2PQDA 2QFUA 1NAWA 3ZH4A 4CLQA 1EJCA 1RF5A 1DLGA 3KQJA 4E7CA 1X8TA 2GGAA 1RYWA 3TV1A 4O8JA 3SWGA 4FQDA 3KR6A 3UPKA 2QFTA 3FK1A 1MI4A 2AA9A 2PQBA 3SLHA 1YBGA 1RF6A 2PQCA 1A2NA 3NVSA 3V4TA 4E7DA 3RMTA 4E7BA 1QMIA 2RL1A 3KGDA 3TUTA 1EJDA
chains in the Genus database with same CATH topology
1RF4A 3R38A 3LTHA 3ZH3A 3SWEA 1Q36A 3SWQA 2Z2CA 3ISSA 2O0EA 1EYNA 3V5VA 4E7GA 2RL2A 3SPBA 4EGRA 2O0BA 1UAEA 2O0XA 3SU9A 2YVWA 5BQ2A 4N3PA 1P88A 3KQAA 2GG6A 3FJXA 3FK0A 2QFSA 1G6TA 3ROIA 3SWIA 2PQ9A 2GGDA 2BJBA 3SWAA 2O0ZA 3SWDA 5U4HA 1Q3GA 5BS5A 4E7FA 3SG1A 4EIIA 2O0DA 2GG4A 3TI2A 4ZNDA 5BUFA 4E7EA 4R7UA 1G6SA 3TR1A 3FJZA 2O15A 1X8RA 3VCYA 4GFPA 1P89A 2AAYA 2QFQA 2PQDA 2QFUA 1NAWA 3ZH4A 1EJCA 1RF5A 1DLGA 3KQJA 4E7CA 1X8TA 2GGAA 1RYWA 3SWGA 4FQDA 3KR6A 3UPKA 2QFTA 3FK1A 1MI4A 2AA9A 2PQBA 3SLHA 1YBGA 1RF6A 2PQCA 1A2NA 3NVSA 3V4TA 4E7DA 3RMTA 4E7BA 2RL1A 1EJDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RF4 A;  3R38 A;  3LTH A;  3ZH3 A;  3SWE A;  1Q36 A;  3SWQ A;  2Z2C A;  3ISS A;  2O0E A;  1EYN A;  3V5V A;  4E7G A;  2RL2 A;  3SPB A;  4EGR A;  2O0B A;  1UAE A;  2O0X A;  3SU9 A;  2YVW A;  5BQ2 A;  4N3P A;  1P88 A;  3KQA A;  2GG6 A;  3FJX A;  3FK0 A;  2QFS A;  1G6T A;  3ROI A;  3SWI A;  2PQ9 A;  2GGD A;  2BJB A;  3SWA A;  2O0Z A;  3SWD A;  5U4H A;  1Q3G A;  5BS5 A;  4E7F A;  3SG1 A;  4EII A;  2O0D A;  2GG4 A;  3TI2 A;  4ZND A;  5BUF A;  4E7E A;  4R7U A;  1G6S A;  3TR1 A;  3FJZ A;  2O15 A;  1X8R A;  3VCY A;  4GFP A;  1P89 A;  2AAY A;  2QFQ A;  2PQD A;  2QFU A;  1NAW A;  3ZH4 A;  1EJC A;  1RF5 A;  1DLG A;  3KQJ A;  4E7C A;  1X8T A;  2GGA A;  1RYW A;  3SWG A;  4FQD A;  3KR6 A;  3UPK A;  2QFT A;  3FK1 A;  1MI4 A;  2AA9 A;  2PQB A;  3SLH A;  1YBG A;  1RF6 A;  2PQC A;  1A2N A;  3NVS A;  3V4T A;  4E7D A;  3RMT A;  4E7B A;  2RL1 A;  1EJD A; 
#chains in the Genus database with same CATH topology
 4O89 A;  1RF4 A;  3R38 A;  3LTH A;  3ZH3 A;  3SWE A;  1Q36 A;  3SWQ A;  2Z2C A;  3ISS A;  2O0E A;  1EYN A;  3V5V A;  4E7G A;  2RL2 A;  3TUX A;  3SPB A;  4EGR A;  2O0B A;  1UAE A;  2O0X A;  3TW3 A;  3SU9 A;  2YVW A;  5BQ2 A;  4N3P A;  1P88 A;  3KQA A;  2GG6 A;  3FJX A;  3FK0 A;  2QFS A;  1G6T A;  3ROI A;  3SWI A;  2PQ9 A;  2GGD A;  2BJB A;  3SWA A;  2O0Z A;  3SWD A;  5U4H A;  1Q3G A;  1QMH A;  5BS5 A;  4E7F A;  3SG1 A;  4EII A;  2O0D A;  2GG4 A;  3TI2 A;  4ZND A;  5BUF A;  4E7E A;  4R7U A;  3PQV A;  1G6S A;  3TR1 A;  3FJZ A;  2O15 A;  1X8R A;  3VCY A;  4GFP A;  1P89 A;  2AAY A;  2QFQ A;  2PQD A;  2QFU A;  1NAW A;  3ZH4 A;  4CLQ A;  1EJC A;  1RF5 A;  1DLG A;  3KQJ A;  4E7C A;  1X8T A;  2GGA A;  1RYW A;  3TV1 A;  4O8J A;  3SWG A;  4FQD A;  3KR6 A;  3UPK A;  2QFT A;  3FK1 A;  1MI4 A;  2AA9 A;  2PQB A;  3SLH A;  1YBG A;  1RF6 A;  2PQC A;  1A2N A;  3NVS A;  3V4T A;  4E7D A;  3RMT A;  4E7B A;  1QMI A;  2RL1 A;  3KGD A;  3TUT A;  1EJD A; 
#chains in the Genus database with same CATH homology
 1RF4 A;  3R38 A;  3LTH A;  3ZH3 A;  3SWE A;  1Q36 A;  3SWQ A;  2Z2C A;  3ISS A;  2O0E A;  1EYN A;  3V5V A;  4E7G A;  2RL2 A;  3SPB A;  4EGR A;  2O0B A;  1UAE A;  2O0X A;  3SU9 A;  2YVW A;  5BQ2 A;  4N3P A;  1P88 A;  3KQA A;  2GG6 A;  3FJX A;  3FK0 A;  2QFS A;  1G6T A;  3ROI A;  3SWI A;  2PQ9 A;  2GGD A;  2BJB A;  3SWA A;  2O0Z A;  3SWD A;  5U4H A;  1Q3G A;  5BS5 A;  4E7F A;  3SG1 A;  4EII A;  2O0D A;  2GG4 A;  3TI2 A;  4ZND A;  5BUF A;  4E7E A;  4R7U A;  1G6S A;  3TR1 A;  3FJZ A;  2O15 A;  1X8R A;  3VCY A;  4GFP A;  1P89 A;  2AAY A;  2QFQ A;  2PQD A;  2QFU A;  1NAW A;  3ZH4 A;  1EJC A;  1RF5 A;  1DLG A;  3KQJ A;  4E7C A;  1X8T A;  2GGA A;  1RYW A;  3SWG A;  4FQD A;  3KR6 A;  3UPK A;  2QFT A;  3FK1 A;  1MI4 A;  2AA9 A;  2PQB A;  3SLH A;  1YBG A;  1RF6 A;  2PQC A;  1A2N A;  3NVS A;  3V4T A;  4E7D A;  3RMT A;  4E7B A;  2RL1 A;  1EJD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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