3LTHA

E. cloacae mura dead-end complex with unag and fosfomycin
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
419
structure length
418
Chain Sequence
MDKFRVQGPTRLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLTQLGTKVERGSVWIDASNVNNFSAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIFGLEKLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTIIENAAREPEIVDTANFLVALGAKISGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISGGKIVCRNAQPDTLDAVLAKLREAGADIETGEDWISLDMHGKRPKAVTVRTAPHPAFPTDMQAQFTLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
pubmed doi rcsb
molecule tags Transferase/antibiotic
source organism Enterobacter cloacae
molecule keywords UDP-N-acetylglucosamine 1-carboxyvinyltransferase
total genus 141
structure length 418
sequence length 419
ec nomenclature ec 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.
pdb deposition date 2010-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00275 EPSP_synthase EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 3lthA02
3.65.10.10 Alpha Beta Alpha-beta prism UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chain Enolpyruvate transferase domain 3lthA01
2GG6A 2PQ9A 2PQDA 4FQDA 3VCYA 3SWQA 5BS5A 2PQBA 2GG4A 1EYNA 1P88A 3SU9A 3V4TA 2YVWA 1G6TA 2O0DA 3FK0A 1UAEA 2RL1A 1EJDA 4E7FA 4ZNDA 3FJZA 3KR6A 3SWEA 2O15A 1DLGA 3SWAA 1RYWA 4E7GA 1P89A 3SWDA 3FJXA 4EGRA 3SWIA 1RF5A 2QFQA 4EIIA 3LTHA 4E7CA 2O0EA 2AAYA 2O0ZA 3NVSA 2Z2CA 3RMTA 3KQAA 3FK1A 3SLHA 3R38A 2QFTA 3UPKA 3ZH3A 1Q36A 2QFUA 1Q3GA 2AA9A 4E7BA 4R7UA 1A2NA 3TR1A 3SPBA 1MI4A 3ZH4A 2RL2A 3V5VA 1YBGA 3SWGA 1EJCA 4E7DA 1RF6A 5BUFA 3ROIA 4N3PA 2BJBA 2GGAA 2O0XA 4E7EA 1X8TA 2GGDA 3ISSA 2PQCA 1G6SA 5U4HA 1RF4A 3SG1A 4GFPA 5BQ2A 2QFSA 1X8RA 1NAWA 2O0BA 3KQJA 3TI2A
chains in the Genus database with same CATH superfamily
3TW3A 2GG6A 2PQ9A 3PQVA 2PQDA 4FQDA 4O8JA 3VCYA 3SWQA 5BS5A 2PQBA 2GG4A 1EYNA 1P88A 3SU9A 3V4TA 2YVWA 1G6TA 3KGDA 2O0DA 3FK0A 4O89A 1UAEA 2RL1A 1EJDA 4E7FA 4ZNDA 3FJZA 3KR6A 3TUXA 1QMHA 3SWEA 2O15A 1DLGA 3SWAA 1RYWA 4E7GA 1P89A 3SWDA 3FJXA 4EGRA 3SWIA 1RF5A 2QFQA 4EIIA 3LTHA 4E7CA 2O0EA 2AAYA 2O0ZA 3TV1A 3NVSA 2Z2CA 3RMTA 1QMIA 3FK1A 3KQAA 3SLHA 3R38A 2QFTA 3UPKA 3ZH3A 4CLQA 1Q36A 2QFUA 3TUTA 1Q3GA 2AA9A 4E7BA 4R7UA 1A2NA 3TR1A 3SPBA 1MI4A 3ZH4A 2RL2A 3V5VA 1YBGA 3SWGA 1EJCA 4E7DA 1RF6A 5BUFA 3ROIA 4N3PA 2BJBA 2GGAA 2O0XA 4E7EA 1X8TA 2GGDA 3ISSA 2PQCA 1G6SA 5U4HA 1RF4A 3SG1A 4GFPA 5BQ2A 2QFSA 1X8RA 1NAWA 2O0BA 3KQJA 3TI2A
chains in the Genus database with same CATH topology
2GG6A 2PQ9A 2PQDA 4FQDA 3VCYA 3SWQA 5BS5A 2PQBA 2GG4A 1EYNA 1P88A 3SU9A 3V4TA 2YVWA 1G6TA 2O0DA 3FK0A 1UAEA 2RL1A 1EJDA 4E7FA 4ZNDA 3FJZA 3KR6A 3SWEA 2O15A 1DLGA 3SWAA 1RYWA 4E7GA 1P89A 3SWDA 3FJXA 4EGRA 3SWIA 1RF5A 2QFQA 4EIIA 3LTHA 4E7CA 2O0EA 2AAYA 2O0ZA 3NVSA 2Z2CA 3RMTA 3KQAA 3FK1A 3SLHA 3R38A 2QFTA 3UPKA 3ZH3A 1Q36A 2QFUA 1Q3GA 2AA9A 4E7BA 4R7UA 1A2NA 3TR1A 3SPBA 1MI4A 3ZH4A 2RL2A 3V5VA 1YBGA 3SWGA 1EJCA 4E7DA 1RF6A 5BUFA 3ROIA 4N3PA 2BJBA 2GGAA 2O0XA 4E7EA 1X8TA 2GGDA 3ISSA 2PQCA 1G6SA 5U4HA 1RF4A 3SG1A 4GFPA 5BQ2A 2QFSA 1X8RA 1NAWA 2O0BA 3KQJA 3TI2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GG6 A;  2PQ9 A;  2PQD A;  4FQD A;  3VCY A;  3SWQ A;  5BS5 A;  2PQB A;  2GG4 A;  1EYN A;  1P88 A;  3SU9 A;  3V4T A;  2YVW A;  1G6T A;  2O0D A;  3FK0 A;  1UAE A;  2RL1 A;  1EJD A;  4E7F A;  4ZND A;  3FJZ A;  3KR6 A;  3SWE A;  2O15 A;  1DLG A;  3SWA A;  1RYW A;  4E7G A;  1P89 A;  3SWD A;  3FJX A;  4EGR A;  3SWI A;  1RF5 A;  2QFQ A;  4EII A;  3LTH A;  4E7C A;  2O0E A;  2AAY A;  2O0Z A;  3NVS A;  2Z2C A;  3RMT A;  3KQA A;  3FK1 A;  3SLH A;  3R38 A;  2QFT A;  3UPK A;  3ZH3 A;  1Q36 A;  2QFU A;  1Q3G A;  2AA9 A;  4E7B A;  4R7U A;  1A2N A;  3TR1 A;  3SPB A;  1MI4 A;  3ZH4 A;  2RL2 A;  3V5V A;  1YBG A;  3SWG A;  1EJC A;  4E7D A;  1RF6 A;  5BUF A;  3ROI A;  4N3P A;  2BJB A;  2GGA A;  2O0X A;  4E7E A;  1X8T A;  2GGD A;  3ISS A;  2PQC A;  1G6S A;  5U4H A;  1RF4 A;  3SG1 A;  4GFP A;  5BQ2 A;  2QFS A;  1X8R A;  1NAW A;  2O0B A;  3KQJ A;  3TI2 A; 
#chains in the Genus database with same CATH topology
 3TW3 A;  2GG6 A;  2PQ9 A;  3PQV A;  2PQD A;  4FQD A;  4O8J A;  3VCY A;  3SWQ A;  5BS5 A;  2PQB A;  2GG4 A;  1EYN A;  1P88 A;  3SU9 A;  3V4T A;  2YVW A;  1G6T A;  3KGD A;  2O0D A;  3FK0 A;  4O89 A;  1UAE A;  2RL1 A;  1EJD A;  4E7F A;  4ZND A;  3FJZ A;  3KR6 A;  3TUX A;  1QMH A;  3SWE A;  2O15 A;  1DLG A;  3SWA A;  1RYW A;  4E7G A;  1P89 A;  3SWD A;  3FJX A;  4EGR A;  3SWI A;  1RF5 A;  2QFQ A;  4EII A;  3LTH A;  4E7C A;  2O0E A;  2AAY A;  2O0Z A;  3TV1 A;  3NVS A;  2Z2C A;  3RMT A;  1QMI A;  3FK1 A;  3KQA A;  3SLH A;  3R38 A;  2QFT A;  3UPK A;  3ZH3 A;  4CLQ A;  1Q36 A;  2QFU A;  3TUT A;  1Q3G A;  2AA9 A;  4E7B A;  4R7U A;  1A2N A;  3TR1 A;  3SPB A;  1MI4 A;  3ZH4 A;  2RL2 A;  3V5V A;  1YBG A;  3SWG A;  1EJC A;  4E7D A;  1RF6 A;  5BUF A;  3ROI A;  4N3P A;  2BJB A;  2GGA A;  2O0X A;  4E7E A;  1X8T A;  2GGD A;  3ISS A;  2PQC A;  1G6S A;  5U4H A;  1RF4 A;  3SG1 A;  4GFP A;  5BQ2 A;  2QFS A;  1X8R A;  1NAW A;  2O0B A;  3KQJ A;  3TI2 A; 
#chains in the Genus database with same CATH homology
 2GG6 A;  2PQ9 A;  2PQD A;  4FQD A;  3VCY A;  3SWQ A;  5BS5 A;  2PQB A;  2GG4 A;  1EYN A;  1P88 A;  3SU9 A;  3V4T A;  2YVW A;  1G6T A;  2O0D A;  3FK0 A;  1UAE A;  2RL1 A;  1EJD A;  4E7F A;  4ZND A;  3FJZ A;  3KR6 A;  3SWE A;  2O15 A;  1DLG A;  3SWA A;  1RYW A;  4E7G A;  1P89 A;  3SWD A;  3FJX A;  4EGR A;  3SWI A;  1RF5 A;  2QFQ A;  4EII A;  3LTH A;  4E7C A;  2O0E A;  2AAY A;  2O0Z A;  3NVS A;  2Z2C A;  3RMT A;  3KQA A;  3FK1 A;  3SLH A;  3R38 A;  2QFT A;  3UPK A;  3ZH3 A;  1Q36 A;  2QFU A;  1Q3G A;  2AA9 A;  4E7B A;  4R7U A;  1A2N A;  3TR1 A;  3SPB A;  1MI4 A;  3ZH4 A;  2RL2 A;  3V5V A;  1YBG A;  3SWG A;  1EJC A;  4E7D A;  1RF6 A;  5BUF A;  3ROI A;  4N3P A;  2BJB A;  2GGA A;  2O0X A;  4E7E A;  1X8T A;  2GGD A;  3ISS A;  2PQC A;  1G6S A;  5U4H A;  1RF4 A;  3SG1 A;  4GFP A;  5BQ2 A;  2QFS A;  1X8R A;  1NAW A;  2O0B A;  3KQJ A;  3TI2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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