2WYC | Genus

Total Genus 55

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	55
sequence length	164
structure length	164
Chain Sequence	TGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Pseudomonas aeruginosa
publication title	The Quorum-Quenching N-Acyl Homoserine Lactone Acylase Pvdq is an Ntn-Hydrolase with an Unusual Substrate-Binding Pocket pubmed doi rcsb
molecule keywords	ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT ALPHA
total genus	55
structure length	164
sequence length	164
ec nomenclature	ec 3.5.1.97: Acyl-homoserine-lactone acylase.
pdb deposition date	2009-11-16

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.439.10	Mainly Alpha	Orthogonal Bundle	Penicillin Amidohydrolase; domain 1	Penicillin Amidohydrolase, domain 1	2wycA00

1AI7A 1CP9A 1AJPA 3K3WA 1GM7A 1K5QA 4K2FA 2WYDA 4WKVA 4WKSA 2WYCA 4YF9A 1AI6A 1K5SA 1FM2A 1K7DA 1PNMA 3JTRA 1GM9A 3L94A 1AJNA 1GK9A 1JW0A 3L91A 3SRAA 3SRBA 1FXHA 1JVZA 4YFBA 1GKFA 4HSTA 1GM8A 4K2GA 4PELA 4YFAA 4M1JA 1PNLA 4HSRA 1E3AA 1GK1A 2AE4A 1FXVA 2WYEA 3ML0A 1KECA 4BTHA 4E56A 4E55A 2AE5A 2WYBA 4WKTA 4E57A 2ADVA 4WKUA 3JTQA 1GK0A 1PNKA 2AE3A 1OR0A 3S8RA 1KEHA 4PEMA 1H2GA 1AJQA 1GHDA 3SRCA 1AI4A 1JX9A 1AI5A
chains in the Genus database with same CATH superfamily

1AI7A 1CP9A 1AJPA 3K3WA 1GM7A 1K5QA 4K2FA 2WYDA 4WKVA 3FGRA 2WYCA 4WKSA 4YF9A 1AI6A 1K5SA 1FM2A 1K7DA 1PNMA 3JTRA 1GM9A 3L94A 1AJNA 1GK9A 1JW0A 3L91A 3SRAA 3SRBA 1FXHA 1JVZA 4YFBA 1GKFA 4HSTA 1GM8A 4K2GA 4PELA 4BWCA 4YFAA 4M1JA 1PNLA 4HSRA 1E3AA 1GK1A 2AE4A 1FXVA 2WYEA 3ML0A 1KECA 4BTHA 4E56A 4E55A 2AE5A 2WYBA 4WKTA 3FGTA 4E57A 2ADVA 4WKUA 3JTQA 1GK0A 1PNKA 2AE3A 1OR0A 3S8RA 1KEHA 4PEMA 1H2GA 1AJQA 1GHDA 3SRCA 1AI4A 1JX9A 1AI5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1AI7 A;  1CP9 A;  1AJP A;  3K3W A;  1GM7 A;  1K5Q A;  4K2F A;  2WYD A;  4WKV A;  4WKS A;  2WYC A;  4YF9 A;  1AI6 A;  1K5S A;  1FM2 A;  1K7D A;  1PNM A;  3JTR A;  1GM9 A;  3L94 A;  1AJN A;  1GK9 A;  1JW0 A;  3L91 A;  3SRA A;  3SRB A;  1FXH A;  1JVZ A;  4YFB A;  1GKF A;  4HST A;  1GM8 A;  4K2G A;  4PEL A;  4YFA A;  4M1J A;  1PNL A;  4HSR A;  1E3A A;  1GK1 A;  2AE4 A;  1FXV A;  2WYE A;  3ML0 A;  1KEC A;  4BTH A;  4E56 A;  4E55 A;  2AE5 A;  2WYB A;  4WKT A;  4E57 A;  2ADV A;  4WKU A;  3JTQ A;  1GK0 A;  1PNK A;  2AE3 A;  1OR0 A;  3S8R A;  1KEH A;  4PEM A;  1H2G A;  1AJQ A;  1GHD A;  3SRC A;  1AI4 A;  1JX9 A;  1AI5 A; 
#chains in the Genus database with same CATH topology
 1AI7 A;  1CP9 A;  1AJP A;  3K3W A;  1GM7 A;  1K5Q A;  4K2F A;  2WYD A;  4WKV A;  3FGR A;  2WYC A;  4WKS A;  4YF9 A;  1AI6 A;  1K5S A;  1FM2 A;  1K7D A;  1PNM A;  3JTR A;  1GM9 A;  3L94 A;  1AJN A;  1GK9 A;  1JW0 A;  3L91 A;  3SRA A;  3SRB A;  1FXH A;  1JVZ A;  4YFB A;  1GKF A;  4HST A;  1GM8 A;  4K2G A;  4PEL A;  4BWC A;  4YFA A;  4M1J A;  1PNL A;  4HSR A;  1E3A A;  1GK1 A;  2AE4 A;  1FXV A;  2WYE A;  3ML0 A;  1KEC A;  4BTH A;  4E56 A;  4E55 A;  2AE5 A;  2WYB A;  4WKT A;  3FGT A;  4E57 A;  2ADV A;  4WKU A;  3JTQ A;  1GK0 A;  1PNK A;  2AE3 A;  1OR0 A;  3S8R A;  1KEH A;  4PEM A;  1H2G A;  1AJQ A;  1GHD A;  3SRC A;  1AI4 A;  1JX9 A;  1AI5 A; 
#chains in the Genus database with same CATH homology
 1AI7 A;  1CP9 A;  1AJP A;  3K3W A;  1GM7 A;  1K5Q A;  4K2F A;  2WYD A;  4WKV A;  4WKS A;  2WYC A;  4YF9 A;  1AI6 A;  1K5S A;  1FM2 A;  1K7D A;  1PNM A;  3JTR A;  1GM9 A;  3L94 A;  1AJN A;  1GK9 A;  1JW0 A;  3L91 A;  3SRA A;  3SRB A;  1FXH A;  1JVZ A;  4YFB A;  1GKF A;  4HST A;  1GM8 A;  4K2G A;  4PEL A;  4YFA A;  4M1J A;  1PNL A;  4HSR A;  1E3A A;  1GK1 A;  2AE4 A;  1FXV A;  2WYE A;  3ML0 A;  1KEC A;  4BTH A;  4E56 A;  4E55 A;  2AE5 A;  2WYB A;  4WKT A;  4E57 A;  2ADV A;  4WKU A;  3JTQ A;  1GK0 A;  1PNK A;  2AE3 A;  1OR0 A;  3S8R A;  1KEH A;  4PEM A;  1H2G A;  1AJQ A;  1GHD A;  3SRC A;  1AI4 A;  1JX9 A;  1AI5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2WYCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

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