2WYDA

The quorum quenching n-acyl homoserine lactone acylase pvdq in complex with dodecanoic acid
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
164
structure length
164
Chain Sequence
TGLAADIRWTAYGVPHIRAKDERGLGYGIGYAYARDNACLLAEEIVTARGERARYFGSEGKSSAELDNLPSDIFYAWLNQPEALQAFWQAQTPAVRQLLEGYAAGFNRFLREADGKTTSCLGQPWLRAIATDDLLRLTRRLLVEGGVGQFADALVAAAPPGAEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Quorum-Quenching N-Acyl Homoserine Lactone Acylase Pvdq is an Ntn-Hydrolase with an Unusual Substrate-Binding Pocket
pubmed doi rcsb
molecule tags Hydrolase
source organism Pseudomonas aeruginosa
molecule keywords ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT ALPHA
total genus 55
structure length 164
sequence length 164
ec nomenclature ec 3.5.1.97: Acyl-homoserine-lactone acylase.
pdb deposition date 2009-11-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.439.10 Mainly Alpha Orthogonal Bundle Penicillin Amidohydrolase; domain 1 Penicillin Amidohydrolase, domain 1 2wydA00
1AI7A 1JVZA 1AI6A 1H2GA 4HSRA 1K7DA 1GK9A 1FXVA 1AJQA 1PNKA 4YFAA 2AE4A 2AE5A 2WYDA 4HSTA 4WKTA 4WKSA 1PNMA 4YF9A 1GK0A 3ML0A 1GK1A 3S8RA 4E55A 1K5SA 1AJPA 4YFBA 1FXHA 1GHDA 4PELA 1PNLA 2ADVA 1GM9A 1GM8A 3SRAA 1AI4A 4E56A 1JW0A 3JTQA 3SRCA 4BTHA 1CP9A 1KECA 4M1JA 1OR0A 3K3WA 3JTRA 4WKVA 1KEHA 4K2FA 1E3AA 1GKFA 2WYCA 2WYEA 3L94A 4K2GA 1JX9A 1GM7A 1AJNA 1K5QA 1AI5A 1FM2A 4PEMA 3SRBA 3L91A 4E57A 2AE3A 2WYBA 4WKUA
chains in the Genus database with same CATH superfamily
1AI7A 1JVZA 1AI6A 1H2GA 3FGRA 1K7DA 3FGTA 4HSRA 1GK9A 1FXVA 1AJQA 1PNKA 4YFAA 2AE4A 2AE5A 2WYDA 4HSTA 4WKTA 4WKSA 1PNMA 4YF9A 1GK0A 3ML0A 1GK1A 3S8RA 4E55A 1K5SA 1AJPA 4YFBA 1FXHA 1GHDA 4PELA 1PNLA 2ADVA 1GM9A 1GM8A 3SRAA 1AI4A 4E56A 1JW0A 3JTQA 3SRCA 4BTHA 1CP9A 1KECA 4M1JA 1OR0A 3K3WA 3JTRA 4WKVA 4BWCA 1KEHA 4K2FA 1E3AA 1GKFA 2WYCA 2WYEA 3L94A 4K2GA 1JX9A 1GM7A 1AJNA 1K5QA 1AI5A 1FM2A 4PEMA 3SRBA 3L91A 4E57A 2AE3A 2WYBA 4WKUA
chains in the Genus database with same CATH topology
1AI7A 1JVZA 1AI6A 1H2GA 4HSRA 1K7DA 1GK9A 1FXVA 1AJQA 1PNKA 4YFAA 2AE4A 2AE5A 2WYDA 4HSTA 4WKTA 4WKSA 1PNMA 4YF9A 1GK0A 3ML0A 1GK1A 3S8RA 4E55A 1K5SA 1AJPA 4YFBA 1FXHA 1GHDA 4PELA 1PNLA 2ADVA 1GM9A 1GM8A 3SRAA 1AI4A 4E56A 1JW0A 3JTQA 3SRCA 4BTHA 1CP9A 1KECA 4M1JA 1OR0A 3K3WA 3JTRA 4WKVA 1KEHA 4K2FA 1E3AA 1GKFA 2WYCA 2WYEA 3L94A 4K2GA 1JX9A 1GM7A 1AJNA 1K5QA 1AI5A 1FM2A 4PEMA 3SRBA 3L91A 4E57A 2AE3A 2WYBA 4WKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AI7 A;  1JVZ A;  1AI6 A;  1H2G A;  4HSR A;  1K7D A;  1GK9 A;  1FXV A;  1AJQ A;  1PNK A;  4YFA A;  2AE4 A;  2AE5 A;  2WYD A;  4HST A;  4WKT A;  4WKS A;  1PNM A;  4YF9 A;  1GK0 A;  3ML0 A;  1GK1 A;  3S8R A;  4E55 A;  1K5S A;  1AJP A;  4YFB A;  1FXH A;  1GHD A;  4PEL A;  1PNL A;  2ADV A;  1GM9 A;  1GM8 A;  3SRA A;  1AI4 A;  4E56 A;  1JW0 A;  3JTQ A;  3SRC A;  4BTH A;  1CP9 A;  1KEC A;  4M1J A;  1OR0 A;  3K3W A;  3JTR A;  4WKV A;  1KEH A;  4K2F A;  1E3A A;  1GKF A;  2WYC A;  2WYE A;  3L94 A;  4K2G A;  1JX9 A;  1GM7 A;  1AJN A;  1K5Q A;  1AI5 A;  1FM2 A;  4PEM A;  3SRB A;  3L91 A;  4E57 A;  2AE3 A;  2WYB A;  4WKU A; 
#chains in the Genus database with same CATH topology
 1AI7 A;  1JVZ A;  1AI6 A;  1H2G A;  3FGR A;  1K7D A;  3FGT A;  4HSR A;  1GK9 A;  1FXV A;  1AJQ A;  1PNK A;  4YFA A;  2AE4 A;  2AE5 A;  2WYD A;  4HST A;  4WKT A;  4WKS A;  1PNM A;  4YF9 A;  1GK0 A;  3ML0 A;  1GK1 A;  3S8R A;  4E55 A;  1K5S A;  1AJP A;  4YFB A;  1FXH A;  1GHD A;  4PEL A;  1PNL A;  2ADV A;  1GM9 A;  1GM8 A;  3SRA A;  1AI4 A;  4E56 A;  1JW0 A;  3JTQ A;  3SRC A;  4BTH A;  1CP9 A;  1KEC A;  4M1J A;  1OR0 A;  3K3W A;  3JTR A;  4WKV A;  4BWC A;  1KEH A;  4K2F A;  1E3A A;  1GKF A;  2WYC A;  2WYE A;  3L94 A;  4K2G A;  1JX9 A;  1GM7 A;  1AJN A;  1K5Q A;  1AI5 A;  1FM2 A;  4PEM A;  3SRB A;  3L91 A;  4E57 A;  2AE3 A;  2WYB A;  4WKU A; 
#chains in the Genus database with same CATH homology
 1AI7 A;  1JVZ A;  1AI6 A;  1H2G A;  4HSR A;  1K7D A;  1GK9 A;  1FXV A;  1AJQ A;  1PNK A;  4YFA A;  2AE4 A;  2AE5 A;  2WYD A;  4HST A;  4WKT A;  4WKS A;  1PNM A;  4YF9 A;  1GK0 A;  3ML0 A;  1GK1 A;  3S8R A;  4E55 A;  1K5S A;  1AJP A;  4YFB A;  1FXH A;  1GHD A;  4PEL A;  1PNL A;  2ADV A;  1GM9 A;  1GM8 A;  3SRA A;  1AI4 A;  4E56 A;  1JW0 A;  3JTQ A;  3SRC A;  4BTH A;  1CP9 A;  1KEC A;  4M1J A;  1OR0 A;  3K3W A;  3JTR A;  4WKV A;  1KEH A;  4K2F A;  1E3A A;  1GKF A;  2WYC A;  2WYE A;  3L94 A;  4K2G A;  1JX9 A;  1GM7 A;  1AJN A;  1K5Q A;  1AI5 A;  1FM2 A;  4PEM A;  3SRB A;  3L91 A;  4E57 A;  2AE3 A;  2WYB A;  4WKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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